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1. 发明公开

EP4011906A2 LACTASE ENZYMES WITH IMPROVED PROPERTIES 审中-实审转让
公开(公告)号：EP4011906A2
公开(公告)日：2022-06-15
申请号：EP21211668.5
申请日：2018-04-11
申请人： Chr. Hansen A/S
发明人： RAJ, Hans , SMITH, Pernille , ECKHARDT, Thomas , VOJINOVIC, Vojislav , SCHÖLLER, Charlotte Elisabeth Grüner , VAN DEN BRINK, Johannes Maarten
IPC分类号： C07K14/195 , C12N9/38
摘要： The present invention relates to new improved peptide or dimeric peptides exhibiting beta-galactosidase enzyme activity as well as improved methods for reducing the lactose content in compositions, such as dairy products.

2. 发明公开

EP3975732A1 COMPOSITION COMPRISING LACTOCOCCUS, METHODS AND PRODUCTS THEREOF 审中-实审转让
公开(公告)号：EP3975732A1
公开(公告)日：2022-04-06
申请号：EP20728779.8
申请日：2020-06-02
申请人： Chr. Hansen A/S
发明人： ECKHARDT, Thomas , VINDELOEV, Jannik , NIELSEN, Kristian Fog , OEREGAARD, Gunnar
IPC分类号： A23C19/00 , A23C19/032

3. 发明申请

WO2020240042A1 COMPOSITION COMPRISING LACTOCOCCUS, METHODS AND PRODUCTS THEREOF 审中-公开
公开(公告)号：WO2020240042A1
公开(公告)日：2020-12-03
申请号：PCT/EP2020/065168
申请日：2020-06-02
申请人： CHR. HANSEN A/S
发明人： ECKHARDT, Thomas , VINDELOEV, Jannik , NIELSEN, Kristian Fog , OEREGAARD, Gunnar
IPC分类号： A23C19/00 , A23C19/032
摘要： The present invention relates to Lactococcus starter cultures that are compatible with nisin-producing strains and simultaneously do not degrade nisin. The present invention defines starter cultures that can be used in combination with nisin-producing cultures, without degradation of nisin. Furthermore, it is also disclosed that starter cultures can be made by a combination of nisin-producing strains and strains containing nisin-immunity genes and/or and absent of the gene to prevent degradation of nisin.

4. 发明申请

WO2018189238A1 LACTASE ENZYMES WITH IMPROVED PROPERTIES 审中-公开
公开(公告)号：WO2018189238A1
公开(公告)日：2018-10-18
申请号：PCT/EP2018/059283
申请日：2018-04-11
申请人： CHR. HANSEN A/S
发明人： RAJ, Hans , SMITH, Pernille , ECKHARDT, Thomas , VOJINOVIC, Vojislav , SCHÖLLER, Charlotte Elisabeth Grüner , VAN DEN BRINK, Johannes Maarten
IPC分类号： C07K14/195 , C12N9/38
摘要： The present invention relates to new improved peptide or dimeric peptides exhibiting beta-galactosidase enzyme activity as well as improved methods for reducing the lactose content in compositions optionally at elevated temperatures.

5. 发明公开

EP4164399A1 METHOD OF INCREASING NISIN PRODUCTION INLACTOCOCCUS LACTIS 审中-实审
公开(公告)号：EP4164399A1
公开(公告)日：2023-04-19
申请号：EP21730625.7
申请日：2021-06-10
申请人： Chr. Hansen A/S
发明人： JANZEN, Thomas , CHRISTIANSEN, Ditte Ellegaard , MIKKELSEN, Mia Vissing , ECKHARDT, Thomas
IPC分类号： A23C19/032 , C12R1/225 , A23C9/12 , C12N15/01 , C12P21/02 , C12R1/46 , C07K14/195 , C07K14/315 , C12N1/20

6. 发明公开

EP3609909A1 LACTASE ENZYMES WITH IMPROVED ACTIVITY AT LOW TEMPERATURES 审中-公开
公开(公告)号：EP3609909A1
公开(公告)日：2020-02-19
申请号：EP18716285.4
申请日：2018-04-11
申请人： Chr. Hansen A/S
发明人： RAJ, Hans , SMITH, Pernille , ECKHARDT, Thomas , VOJINOVIC, Vojislav , SCHÖLLER, Charlotte Elisabeth Grüner , VAN DEN BRINK, Johannes Maarten
IPC分类号： C07K14/195 , C12N9/38

7. 发明公开

EP3609908A1 LACTASE ENZYMES WITH IMPROVED PROPERTIES 审中-公开
公开(公告)号：EP3609908A1
公开(公告)日：2020-02-19
申请号：EP18715743.3
申请日：2018-04-11
申请人： Chr. Hansen A/S
发明人： RAJ, Hans , SMITH, Pernille , ECKHARDT, Thomas , VOJINOVIC, Vojislav , SCHÖLLER, Charlotte Elisabeth Grüner , VAN DEN BRINK, Johannes Maarten
IPC分类号： C07K14/195 , C12N9/38

8. 发明申请

WO2021250183A1 METHOD OF INCREASING NISIN PRODUCTION IN LACTOCOCCUS LACTIS 审中-公开
公开(公告)号：WO2021250183A1
公开(公告)日：2021-12-16
申请号：PCT/EP2021/065664
申请日：2021-06-10
申请人： CHR. HANSEN A/S
发明人： JANZEN, Thomas , CHRISTIANSEN, Ditte Ellegaard , MIKKELSEN, Mia Vissing , ECKHARDT, Thomas
IPC分类号： A23C19/032 , C12R1/225 , A23C9/12 , C12N15/01 , C12P21/02 , C12R1/46 , C07K14/195 , C07K14/315 , C12N1/20 , A23V2300/21 , C12N1/205 , C12R2001/46
摘要： The present invention provides a method of increasing nisin production in nisin- producing Lactococcus lactis by inactivating the phage infection protein Pip. The invention also provides nisin-producing Lactococcus lactis in which the phage infection protein is inactivated. The nisin-producing Lactococcus lactis can be used in starter culture for manufacturing food products or other industrial applications.

9. 发明申请

WO2017037046A1 LACTOBACILLUS FERMENTUM BACTERIA WITH ANTIFUNGAL ACTIVITY 审中-公开
标题翻译：具有反真菌活性的乳杆菌酵母菌
公开(公告)号：WO2017037046A1
公开(公告)日：2017-03-09
申请号：PCT/EP2016/070381
申请日：2016-08-30
申请人： CHR. HANSEN A/S
发明人： NIELSEN, Cecilie Lykke Marvig , HORNBAEK, Tina , RASMUSSEN, Pia , POULSEN, Lone , ECKHARDT, Thomas , OEREGAARD, Gunnar , MOGHADAM, Elahe Ghanei
IPC分类号： C12N1/20 , A23C9/123 , A61K35/747 , A23L29/00 , C12R1/225
CPC分类号： C12N1/20 , A23C9/1234 , A23K10/18 , A23L33/135 , A23V2002/00 , A23Y2220/35 , A61K35/747 , C12R1/225 , A23V2200/10
摘要： The present invention relates to a bacterium of the species Lactobacillus fermentum having the ability to inhibit the growth of the fungus Penicillium solitum deposited under the accession No.: DSM32093 or the growth of the fungus Penicillium brevicompactum deposited under the accession No.: DSM32094 by at least 50%. The inhibitory activity can be determined in an assay comprising: (1) preparing a fermented milk product by: (a) inoculating a milk with the Lactobacillus fermentum in a concentration of at least 10 7 CFU/g and with a starter culture, (b) fermenting until a p H of 4.6 is reached, and (c) solidifying the fermented milk by the addition of agar; (2) generating at least one spot of the P. solitum or the P. brevicompactum on the agar solidified fermented milk with a concentration of 500 spores/spot and incubating the 1 same for 7 days at 25 °C; (3) determining the percent inhibition by determining the largest diameter of the colony formed by growth of the P. solitum or P. brevicompactum and expressing the diameter as percent of the largest diameter formed under the same conditions but in the absence of the Lactobacillus fermentum strain. The invention further relates to compositions comprising the bacterium, methods for producing fermented milk products using the bacterium and the products thus obtained.
摘要翻译：本发明涉及具有抑制根据登录号：DSM32093保藏的隐孢子虫青霉菌生长能力的发酵乳杆菌种的细菌，或以保藏号：DSM32094保藏的真菌青霉菌的生长至少50％。可以在包括以下步骤的测定中测定抑制活性：（1）通过以下步骤来制备发酵乳制品：（a）以至少107CFU / g的浓度和发酵剂培养物用发酵乳杆菌接种乳汁，（b）发酵直至达到4.6的ap H，和（c）通过加入琼脂固化发酵乳; （2）在浓度为500个孢子/斑点的琼脂凝固发酵乳上产生至少一个斑点或短枝球菌斑点，并将其在25℃下孵育7天; （3）通过确定由P.solitum或P. brevicompactum的生长形成的菌落的最大直径，并且将直径作为在相同条件下形成的最大直径的百分数来确定抑制百分比，但是在没有发酵乳杆菌的情况下应变。本发明还涉及包含该细菌的组合物，使用该细菌产生发酵乳制品的方法和由此获得的产品。

10. 发明公开

EP4011906A3 LACTASE ENZYMES WITH IMPROVED PROPERTIES 审中-实审转让
公开(公告)号：EP4011906A3
公开(公告)日：2022-09-07
申请号：EP21211668.5
申请日：2018-04-11
申请人： Chr. Hansen A/S
发明人： RAJ, Hans , SMITH, Pernille , ECKHARDT, Thomas , VOJINOVIC, Vojislav , SCHÖLLER, Charlotte Elisabeth Grüner , VAN DEN BRINK, Johannes Maarten
IPC分类号： C07K14/195 , C12N9/38
摘要： The present invention relates to new improved peptide or dimeric peptides exhibiting beta-galactosidase enzyme activity as well as improved methods for reducing the lactose content in compositions, such as dairy products.

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