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1. 发明授权

US06683095B2 CDK inhibitors having 3-hydroxychromen-4-one structure 失效
标题翻译：具有3-羟基色烯-4-酮结构的CDK抑制剂
公开(公告)号：US06683095B2
公开(公告)日：2004-01-27
申请号：US10275066
申请日：2002-11-01
申请人： Chang-Yong Hong , Jin-Ho Lee , Tae-Sik Park , Jong-Hyun Kim , Sei-Hyun Choi , Sook-Kyung Yoon , Hyun-Ho Chung , Ho-Sun Son , Eunice Eun-Kyeong Kim , Seong-Gu Ro , Shin-Wu Jeong , Dong-Myung Kim
发明人： Chang-Yong Hong , Jin-Ho Lee , Tae-Sik Park , Jong-Hyun Kim , Sei-Hyun Choi , Sook-Kyung Yoon , Hyun-Ho Chung , Ho-Sun Son , Eunice Eun-Kyeong Kim , Seong-Gu Ro , Shin-Wu Jeong , Dong-Myung Kim
IPC分类号： A61K31453
CPC分类号： C07D405/04 , C07D311/30 , C07D417/04 , C07D417/14
摘要： A novel 3-hydroxychromen-4-one derivative, pharmaceutically acceptable salt, hydrate, solvate or isomer thereof which is useful as an inhibitor for Cyclin Dependent Kinase (“CDK”) is disclosed. Further, a process for preparing the compound and a composition for suppression or treatment of cancer and diseases induced by cell proliferation such as inflammation, angiostenosis, angiogenesis, etc. is disclosed comprising the compound as an active component together with pharmaceutically acceptable carriers.
摘要翻译：公开了一种可用作细胞周期蛋白依赖性激酶（“CDK”）抑制剂的新型3-羟基色烯-4-酮衍生物，其药学上可接受的盐，水合物，溶剂合物或异构体。此外，公开了一种制备化合物的方法和用于抑制或治疗癌症的组合物以及由细胞增殖如炎症，血管狭窄症，血管发生等引起的疾病，其包括作为活性成分的化合物以及药学上可接受的载体。

2. 发明授权

US06620831B2 Indazoles substituted with 1,1-dioxoisothiazolidine useful as inhibitors of cell proliferation 失效
标题翻译：用1,1-二氧代异噻唑烷代替的吲唑可用作细胞增殖抑制剂
公开(公告)号：US06620831B2
公开(公告)日：2003-09-16
申请号：US10275176
申请日：2002-11-04
申请人： Jin-Ho Lee , Chang-Yong Hong , Tae-Sik Park , Jong-Hyun Kim , Sei-Hyun Choi , Sook-Kyung Yoon , Hyun-Ho Chung , Shin-Wu Jeong , Kwang-Yeon Hwang , Dong-Kyu Shin
发明人： Jin-Ho Lee , Chang-Yong Hong , Tae-Sik Park , Jong-Hyun Kim , Sei-Hyun Choi , Sook-Kyung Yoon , Hyun-Ho Chung , Shin-Wu Jeong , Kwang-Yeon Hwang , Dong-Kyu Shin
IPC分类号： C07D41714
CPC分类号： C07D417/04 , C07D417/14
摘要： The present invention relates to an indazole derivative, pharmaceutically acceptable salt, solvated product and isomer thereof substituted with 1,1-dioxoisothiazolidine which are useful as inhibitors for Cyclin Dependent Kinase(CDK). The present invention also relates to an agent for inhibiting and treating diseases involving cell proliferation, e.g., cancer, inflammation, restenosis, angiogenesis, etc. which comprises the compound of formula (1) as an active ingredient together with a pharmaceutically acceptable carrier.
摘要翻译：本发明涉及可用作细胞周期蛋白依赖性激酶（CDK）抑制剂的1,1-二氧代异噻唑烷取代的吲唑衍生物，药用盐，溶剂合物及其异构体。本发明还涉及包含式（1）化合物作为活性成分的药物可接受的载体的抑制和治疗涉及细胞增殖的疾病，例如癌症，炎症，再狭窄，血管发生等的药剂。

3. 发明授权

US06511978B1 Pyrrole derivatives useful for farnesyl transferase inhibitors and their preparations 失效
标题翻译：可用于法呢基转移酶抑制剂及其制剂的吡咯衍生物
公开(公告)号：US06511978B1
公开(公告)日：2003-01-28
申请号：US09958478
申请日：2001-10-11
申请人： Jong-Sung Koh , Hyun-Il Lee , You-Seung Shin , Hak-Joong Kim , Jin-Ho Lee , Jong-Hyun Kim , Hyun-Ho Chung , Shin-Wu Jeong , Tae-Saeng Choi , Jung-Kwon Yoo , Chung-Mi Kim , Kwi-Hwa Kim , Sun-Hwa Lee , Sang-Kyun Lee
发明人： Jong-Sung Koh , Hyun-Il Lee , You-Seung Shin , Hak-Joong Kim , Jin-Ho Lee , Jong-Hyun Kim , Hyun-Ho Chung , Shin-Wu Jeong , Tae-Saeng Choi , Jung-Kwon Yoo , Chung-Mi Kim , Kwi-Hwa Kim , Sun-Hwa Lee , Sang-Kyun Lee
IPC分类号： C07D40306
CPC分类号： C07D401/14 , C07D403/06 , C07D405/14 , C07D409/14
摘要： The present invention relates to a novel pyrrole derivative which shows an inhibitory activity against farnesyl transferase or pharmaceutically acceptable salts or isomers thereof; to a process for preparation of said compound; and to a pharmaceutical composition such as anti-cancer composition, etc. comprising said compound as an active ingredient together with pharmaceutically acceptable carrier.
摘要翻译：本发明涉及对法呢基转移酶或其药学上可接受的盐或异构体具有抑制活性的新型吡咯衍生物; 涉及制备所述化合物的方法; 以及包含所述化合物作为活性成分以及药学上可接受的载体的药物组合物，例如抗癌组合物等。

4. 发明申请

US20120017911A1 FILTERING FACE-PIECE RESPIRATOR HAVING FOAM SHAPING LAYER 审中-公开
标题翻译：具有泡沫形状层的过滤面罩呼吸器
公开(公告)号：US20120017911A1
公开(公告)日：2012-01-26
申请号：US12843276
申请日：2010-07-26
申请人： Dong-Il Choi , Joo-Youn Kim , Jin-Ho Lee , Seung-Joo Lee
发明人： Dong-Il Choi , Joo-Youn Kim , Jin-Ho Lee , Seung-Joo Lee
IPC分类号： A62B23/02
CPC分类号： A62B18/025 , A41D13/1146 , A62B23/025
摘要： A filtering face mask 10 that has a harness 14 and a mask body 12. The mask body 12 is structured such that a snug facial fit can be achieved without use of additional components such as an elastomeric face seal, nose foam, or nose clip. The mask body 12 includes a filtering structure 18 and a cup-shaped shaping layer 20 where the latter comprises a closed cell foam layer that has a plurality of fluid permeable openings located in it. The openings occupy at least 30% of the total surface area of the shaping layer, including a mid region of the shaping layer. The filtering structure is coextensively disposed over the shaping layer. The shaping layer 20 makes contact with the wearer's face at the mask body perimeter 19 when the respirator is being worn. Despite the open nature of the foam shaping layer over much of its surface area, the use of a foam shaping layer, in conjunction with a coextensive filtering structure, provides sufficient structural integrity or stiffness to prevent mask body collapse during respirator use while also exhibiting a low pressure drop to allow for low breathing resistance and extended wearer comfort.
摘要翻译：具有线束14和面罩主体12的过滤面罩10.面罩主体12被构造成使得可以在不使用诸如弹性体面部密封件，鼻部泡沫或鼻夹的附加部件的情况下实现舒适的面部配合。面罩主体12包括过滤结构18和杯形成形层20，其中后者包括具有多个位于其中的流体可渗透开口的闭孔泡沫层。这些开口占成形层的总表面面积的至少30％，包括成形层的中间区域。过滤结构共同设置在成形层上。当佩戴呼吸器时，成形层20在面具主体周边19处与穿着者的脸部接触。尽管泡沫成型层在其大部分表面积上具有开放性质，但是使用泡沫成形层与共延伸的过滤结构相结合，提供了足够的结构完整性或刚度，以防止呼吸器使用期间的面罩体塌陷，同时也显示出低压降以允许低呼吸阻力和延长佩戴者的舒适度。

5. 发明授权

US07718414B2 Microorganism of Enterobacteriacae genus haboring genes associated with L-carnitine biosynthesis and method of producing L-carnitine using the microorganism 有权
标题翻译：具有与L-肉碱生物合成相关的基因的肠杆菌属的微生物和使用微生物生产L-肉毒碱的方法
公开(公告)号：US07718414B2
公开(公告)日：2010-05-18
申请号：US11994969
申请日：2006-07-07
申请人： Whan-Koo Kang , Bheong-Uk Lee , Young-Hoon Park , Eun-Sung Koh , Jae-Yeong Ju , Jin-Ho Lee , Hye-Won Kim , Hye-Jin Choi
发明人： Whan-Koo Kang , Bheong-Uk Lee , Young-Hoon Park , Eun-Sung Koh , Jae-Yeong Ju , Jin-Ho Lee , Hye-Won Kim , Hye-Jin Choi
IPC分类号： C12P13/00 , C12N1/20
CPC分类号： C12N9/1007 , C12N9/0071 , C12N9/88 , C12P13/007
摘要： Provided is a microorganism that belongs to Enterobacteriacae and a method of producing L-carnitine using the same. The microorganism includes polynucleotide encoding activity of S-adenosylmethionine-6-N-iysine methyltransferase from Neurospora crassa, polynucleotide encoding activity of 6-N-trimethyllysine hydroxylase, polynucleotide encoding activity of 3-hydroxy-6-N-trimethyllysine aldolase, and polynucleotide encoding activity of γ-trimethylaminoaldehyde dehydrogenase and y-butyrobetaine hydroxylase.
摘要翻译：提供属于肠杆菌属的微生物和使用其的L-肉毒碱的生产方法。微生物包括编码来自粗糙脉孢菌的S-腺苷甲硫氨酸-6-N-依赖型甲基转移酶的活性的多核苷酸，编码6-N-三甲基赖氨酸羟化酶活性的多核苷酸，编码3-羟基-6-N-三甲基赖氨酸醛缩酶活性的多核苷酸，以及编码 γ-三甲基氨基醛脱氢酶和γ-丁基甜菜碱羟化酶的活性。

6. 发明授权

US07450186B2 Laser television 有权
标题翻译：激光电视
公开(公告)号：US07450186B2
公开(公告)日：2008-11-11
申请号：US11131852
申请日：2005-05-18
申请人： Pil-Soo Ahn , Serafimovich Pavel , Jin-Ho Lee , Yong-Kweun Mun , Byoung-Ho Cheong
发明人： Pil-Soo Ahn , Serafimovich Pavel , Jin-Ho Lee , Yong-Kweun Mun , Byoung-Ho Cheong
IPC分类号： H04N5/74
CPC分类号： H04N9/3129
摘要： A laser television including a plurality of lasers for generating different wavelengths of interferential light; a scanner for displaying color images on a screen composed from the light; and a phase diffuser positioned between the lasers and the scanner for diffusing the light from the lasers according to the light's wavelength. The phase diffuser having a boundary surface, through which the light is outputted to the scanner. The boundary surface is slanted with a predetermined angle to regulate the range of diffraction of the light according to the wavelength.
摘要翻译：一种包括用于产生不同波长的干涉光的多个激光器的激光电视机; 用于在由所述光组成的屏幕上显示彩色图像的扫描仪; 位于激光器和扫描仪之间的相位扩散器，用于根据光的波长扩散来自激光器的光。相位扩散器具有边界面，光被输出到扫描器。边界面以预定角度倾斜，以根据波长调节光的衍射范围。

7. 发明申请

US20080254365A1 NEGATIVE ACTIVE MATERIAL FOR RECHARGEABLE LITHIUM BATTERY, METHOD OF PREPARING SAME, AND RECHARGEABLE LITHIUM BATTERY INCLUDING SAME 审中-公开
标题翻译：用于可充电锂电池的负极活性材料，其制备方法和包括其的可充电锂电池
公开(公告)号：US20080254365A1
公开(公告)日：2008-10-16
申请号：US11947708
申请日：2007-11-29
申请人： Tae-Wan Kim , Joon-Sup Kim , Sung-Soo Kim , Ri-Zhu Yin , Jin-Ho Lee , Wan-Uk Choi
发明人： Tae-Wan Kim , Joon-Sup Kim , Sung-Soo Kim , Ri-Zhu Yin , Jin-Ho Lee , Wan-Uk Choi
IPC分类号： H01M4/52 , H01M4/50 , H01M4/58
CPC分类号： H01M4/485 , C01G31/006 , C01G37/006 , C01G39/006 , C01G41/006 , C01G45/1228 , C01G49/009 , C01G51/50 , C01P2002/52 , C01P2002/54 , C01P2002/74 , C01P2006/40 , H01M4/505 , H01M4/525 , H01M4/5825 , H01M10/052
摘要： Negative active materials for rechargeable lithium batteries, manufacturing methods thereof, and rechargeable lithium batteries including the negative active materials are provided. The negative active material includes a compound represented by the Formula Li1+xV1-x-yMyO2+z. In one embodiment, the compound has an average particle size ranging from about 50 nm to about 30 μm. In another embodiment, the negative active material has a ratio of (003) plane diffraction intensity to (104) plane diffraction intensity ranging from about 1:1 to about 1:0.01 when measured using a Cu K α X-ray. According to another embodiment, after five charge/discharge cycles performed at 0.5C, a specific surface area of the negative active material increases to less than about 20 times a specific surface area before the five charge/discharge cycles. The negative active materials may improve battery capacity, and cycle-life characteristics.
摘要翻译：提供了用于可再充电锂电池的负极活性材料，其制造方法和包括负极活性材料的可再充电锂电池。负极活性材料包括由式Li 1 + x 1 O 2-x M 2 O 2 O 2 + z 2表示的化合物， / SUB>。在一个实施方案中，化合物具有约50nm至约30μm的平均粒度。在另一个实施方案中，当使用CuKαX射线测量时，负极活性材料的（003）平面衍射强度与（104）平面衍射强度之比为约1:1至约1:0.01。根据另一个实施方案，在0.5℃下进行五次充电/放电循环之后，负极活性物质的比表面积在五次充电/放电循环之前增加到小于约20倍的比表面积。负极活性材料可以提高电池容量和循环寿命特性。

8. 发明申请

US20080199920A1 S-Adenosylmethionine-6-N-Lysine-Methyltransferase From Neurospora Crassa, A Gene Encoding The Same, A Vector And Host Cell Containing The Same, And Method For Producing Trimethyllysine Using The Host Cell 有权
标题翻译：来自粗糙脉孢菌的S-腺苷甲硫氨酸-6-N-赖氨酸 - 甲基转移酶，编码它的基因，含有它的载体和宿主细胞以及使用宿主细胞产生三甲基赖氨酸的方法
公开(公告)号：US20080199920A1
公开(公告)日：2008-08-21
申请号：US11994938
申请日：2006-07-07
申请人： Whan-Koo Kang , Bheong-Uk Lee , Young-Hoon Park , Eun-Sung Koh , Jae-Yeong Ju , Jin-Ho Lee , Hye-Won Kim , Hye-Jin Choi
发明人： Whan-Koo Kang , Bheong-Uk Lee , Young-Hoon Park , Eun-Sung Koh , Jae-Yeong Ju , Jin-Ho Lee , Hye-Won Kim , Hye-Jin Choi
IPC分类号： C12P13/08 , C12N9/10 , C07H21/04 , C12N15/00 , C12N1/20
CPC分类号： C12P13/08 , C12N9/1085
摘要： Provided is S-adenosylmethionine-6-N-lysine-methyl-transferase obtained from Neνrospora crassa, a polynucleotide encoding the same, a vector and host cell containing the polynucleotide, and a method of producing trimethyllysine by culturing the host cell.
摘要翻译：本发明提供从粗核粗核菌（Nenurospora crassa）获得的S-腺苷甲硫氨酸-6-N-赖氨酸甲基转移酶，其编码该多核苷酸的多核苷酸，含有多核苷酸的载体和宿主细胞，以及通过培养宿主细胞产生三甲基赖氨酸的方法。

9. 发明申请

US20080111460A1 LIGHT EMISSION DEVICE AND DISPLAY DEVICE USING THE LIGHT EMISSION DEVICE AS A LIGHT SOURCE 审中-公开
标题翻译：使用光发射装置作为光源的发光装置和显示装置
公开(公告)号：US20080111460A1
公开(公告)日：2008-05-15
申请号：US11860335
申请日：2007-09-24
申请人： Su-Joung Kang , Kyung-Sun Ryu , Jong-Hoon Shin , Jin-Ho Lee , Kyu-Won Jung , Sang-Jin Lee
发明人： Su-Joung Kang , Kyung-Sun Ryu , Jong-Hoon Shin , Jin-Ho Lee , Kyu-Won Jung , Sang-Jin Lee
IPC分类号： H01J1/88
CPC分类号： H01J63/02 , G02F1/133608 , G02F1/133611 , G02F2001/133625 , H01J63/06
摘要： A light emission device is provided having a first substrate and a second substrate facing each other with a gap therebetween. An electron emission unit is located on one side of the first substrate to emit electrons toward the second substrate. A light emission unit is located on one side of the second substrate to emit visible light by the electrons. A plurality of spacers are provided between the first substrate and the second substrate. The plurality of spacers have a height of about 5 mm-30 mm.
摘要翻译：提供了具有第一基板和第二基板的发光装置，所述第一基板和第二基板彼此面对地间隔开。电子发射单元位于第一衬底的一侧以向第二衬底发射电子。发光单元位于第二基板的一侧，以通过电子发射可见光。多个间隔件设置在第一基板和第二基板之间。多个间隔件具有约5mm至30mm的高度。

10. 发明申请

US20070267961A1 LIGHT EMISSION DEVICE AND DISPLAY DEVICE 失效
标题翻译：光发射装置和显示装置
公开(公告)号：US20070267961A1
公开(公告)日：2007-11-22
申请号：US11690083
申请日：2007-03-22
申请人： Kyung-Sun Ryu , Sang-Jin Lee , Su-Joung Kang , Jin-Ho Lee , Kyu-Won Jung , Jong-Hoon Shin , Pil-Goo Jun
发明人： Kyung-Sun Ryu , Sang-Jin Lee , Su-Joung Kang , Jin-Ho Lee , Kyu-Won Jung , Jong-Hoon Shin , Pil-Goo Jun
IPC分类号： H01J63/04
CPC分类号： H01J31/127 , H01J29/06 , H01J29/481
摘要： A light emission device and a display device using the light emission device as a light source are provided. The light emission device includes a vacuum envelope formed by first and second substrates and a sealing member, first electrodes formed on the first substrate in a first direction, an insulating layer formed on the first substrate and covering the first electrodes, second electrodes formed on the insulating layer in a second direction crossing the first direction, electron emission regions electrically connected to the first electrodes or the second electrodes, a resistive layer for covering a first surface of the insulating layer, the first surface facing the second substrate, a phosphor layer formed on the second substrate, and an anode electrode formed on the phosphor layer.
摘要翻译：提供了一种发光装置和使用该发光装置作为光源的显示装置。发光装置包括由第一和第二基板形成的真空外壳和密封构件，在第一方向上形成在第一基板上的第一电极，形成在第一基板上并覆盖第一电极的绝缘层，形成在第一基板上的第二电极在与第一方向交叉的第二方向上的绝缘层，与第一电极或第二电极电连接的电子发射区，用于覆盖绝缘层的第一表面的电阻层，与第二基板相对的第一表面，形成的荧光体层在第二基板上形成的阳极电极和形成在荧光体层上的阳极电极。

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