专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

WO2006012050A3 CONNECTION STRUCTURES FOR EXTRA-VASCULAR ELECTRODE LEAD BODY 审中-公开
标题翻译：超血管电极导联体的连接结构
公开(公告)号：WO2006012050A3
公开(公告)日：2006-11-30
申请号：PCT/US2005021413
申请日：2005-06-16
申请人： CVRX INC , ROSSING MARTIN A , BOLEA STEPHEN L , MAYER DAVID W , HJELLE AARON , CROWLEY TOM , IRWIN ERIC D
发明人： ROSSING MARTIN A , BOLEA STEPHEN L , MAYER DAVID W , HJELLE AARON , CROWLEY TOM , IRWIN ERIC D
IPC分类号： A61N1/00
CPC分类号： A61N1/3752 , A61N1/05 , A61N1/0551 , A61N1/0558 , H01R4/14 , H01R4/4863 , H01R13/5224 , H01R13/5804 , H01R2201/12
摘要： Connection structures on an extra-vascular electrode lead body improve strain relief and strengthen the transition region where electrical conductors carried by the lead body are joined to individual electrodes at the distal end of the lead. The electrodes include structure or mechanisms for externally securing the electrode assembly to a body part. A first connection structure is located on the lead body proximal the electrodes to anchor the lead body to a first anchor location in the body that generally moves in concert with the body part. A second connection structure is located on the lead body proximal to the first connection structure to anchor the lead body to a second anchor location that is at least partially independent of movement of the body part. The first and second anchor location are offset by a distance that is less than a distance between the first and second connection structures to provide strain relief for the electrodes.
摘要翻译：血管外电极导线体上的连接结构改善了应变释放并加强了由导线体携带的电导体连接到导线远端处的单独电极的过渡区域。电极包括用于将电极组件外部固定到身体部分的结构或机构。第一连接结构位于引线体上靠近电极处，以将引线体锚定到体内的第一锚定位置，该第一锚定位置通常与身体部位一致地移动。第二连接结构位于第一连接结构近端的引线主体上，以将引线主体锚定到第二锚定位置，第二锚定位置至少部分独立于主体部分的运动。第一和第二锚定位置偏移的距离小于第一和第二连接结构之间的距离，以为电极提供应力消除。

2. 发明申请

WO2006012033A2 LOCKOUT CONNECTOR ARRANGEMENT FOR IMPLANTABLE MEDICAL DEVICE 审中-公开
标题翻译：用于植入式医疗装置的闭锁连接器装置
公开(公告)号：WO2006012033A2
公开(公告)日：2006-02-02
申请号：PCT/US2005021299
申请日：2005-06-15
申请人： CVRX INC , ROSSING MARTIN A , BOLEA STEPHEN L , HJELLE AARON , HENRY JAMES T , PEDERSEN BRAD D
发明人： ROSSING MARTIN A , BOLEA STEPHEN L , HJELLE AARON , HENRY JAMES T , PEDERSEN BRAD D
IPC分类号： A61N1/375
CPC分类号： A61N1/3752
摘要： A lockout connector arrangement for implantable medical devices having at least one port for receiving a non-cardiac lead connector selectively permits only certain electrical leads to be connected to the implantable medical device. A lead connector pin of a non-cardiac lead connector is specially designed to be larger than a DF-1 lead connector pin, but smaller than an IS-1 lead connector pin. A corresponding header of implantable pulse generator has a connector port for a non-cardiac lead with a proximal-most portion that is larger than the DF-1 lead connector pin, but smaller than the IS-1 lead connector pin; and otherwise generally consistent with the other dimensions of an ISO standard IS-1 pacemaker lead connector.
摘要翻译：具有用于接纳非心脏导联连接器的至少一个端口的植入式医疗装置的锁定连接器装置选择性地仅允许某些电导线连接至植入式医疗装置。非心脏引线连接器的引脚连接器引脚特别设计为比DF-1引脚连接器引脚大，但比IS-1引脚连接器引脚小。植入式脉冲发生器的相应头部具有用于非心脏引线的连接器端口，其最近部分大于DF-1引线连接器引脚，但小于IS-1引线连接器引脚; 并且通常与ISO标准IS-1起搏器引线连接器的其他尺寸一致。

3. 发明申请

WO2006041664A2 BAROREFLEX ACTIVATION AND CARDIAC RESYNCHRONIZATION FOR HEART FAILURE TREATMENT 审中-公开
标题翻译：心脏失效治疗的BAROREFLEX激活和心脏再生
公开(公告)号：WO2006041664A2
公开(公告)日：2006-04-20
申请号：PCT/US2005034416
申请日：2005-09-23
申请人： CVRX INC , KIEVAL ROBERT S , ROSSING MARTIN A , IRWIN ERIC D , BRINTNALL JOHN R
发明人： KIEVAL ROBERT S , ROSSING MARTIN A , IRWIN ERIC D , BRINTNALL JOHN R
IPC分类号： A61N1/362
CPC分类号： A61N1/36114 , A61N1/3627
摘要： A method for treating heart failure in a patient involves activating a baroreflex system of the patient with at least one baroreflex activation device and resynchronizing the patient's heart with a cardiac resynchronization device. Activating the baroreflex system and resynchronizing the heart may be performed simultaneously or sequentially, in various embodiments. In some embodiments, one or more patient conditions are sensed, and such condition(s) may be used for setting and/or modifying the baroreflex activation and/or heart resynchronization. A device for treating heart failure includes a baroreflex activation member coupled with a cardiac resynchronization member. Some embodiments further include one or more sensors and a processor. In some embodiments, the device is fully implantable.
摘要翻译：用于治疗患者心力衰竭的方法包括用至少一个压力反射激活装置激活患者的压力反射系统，并用心脏再同步装置重新同步患者的心脏。在各种实施例中，激活压力反射系统和重新同步心脏可以同时或顺序地执行。在一些实施例中，感测到一个或多个患者状况，并且这种状况可用于设置和/或修改压力反射激活和/或心脏再同步。用于治疗心力衰竭的装置包括与心脏再同步构件连接的压力反射激活构件。一些实施例还包括一个或多个传感器和处理器。在一些实施例中，该装置是完全可植入的。

4. 发明申请

WO2006125163A3 IMPLANTABLE ELECTRODE ASSEMBLY HAVING REVERSE ELECTRODE CONFIGURATION 审中-公开
标题翻译：具有反向电极配置的可植入电极组件
公开(公告)号：WO2006125163A3
公开(公告)日：2007-04-05
申请号：PCT/US2006019470
申请日：2006-05-18
申请人： CVRX INC , HAGEN JEFFREY J , COLE MARY L , ROSSING MARTIN A
发明人： HAGEN JEFFREY J , COLE MARY L , ROSSING MARTIN A
IPC分类号： A61N1/00
CPC分类号： A61N1/05 , A61N1/0556 , A61N1/3956
摘要： Methods and apparatus for generating an electric field inside a patient include at least a first electrode and a second electrode on a common implantable substrate. Each of the electrodes has a respective proximal end and a respective distal end. Electrical energy can be applied that causes electrical current to flow simultaneously through the first and second electrodes preferentially from the proximal end of one electrode to the distal end of the other electrode.
摘要翻译：用于在患者体内产生电场的方法和装置包括在可共同植入的基底上的至少第一电极和第二电极。每个电极具有相应的近端和相应的远端。可以施加电能，其导致电流同时通过第一和第二电极从一个电极的近端到另一个电极的远端。

5. 发明申请

WO2005097256A3 STIMULUS REGIMENS FOR CARDIOVASCULAR REFLEX CONTROL 审中-公开
标题翻译：用于心脏反射控制的刺激方案
公开(公告)号：WO2005097256A3
公开(公告)日：2006-11-23
申请号：PCT/US2005011501
申请日：2005-04-04
申请人： CVRX INC , ROSSING MARTIN A , KIEVAL ROBERT S , SERDAR DAVID J , PERSSON BRUCE J
发明人： ROSSING MARTIN A , KIEVAL ROBERT S , SERDAR DAVID J , PERSSON BRUCE J
IPC分类号： A61N1/36 , A61F2/82 , A61N1/05 , A61N1/08 , A61N1/18 , A61N1/32 , A61N1/365
CPC分类号： A61N1/36114 , A61N1/0551 , A61N1/0558 , A61N1/36007 , A61N1/36117 , A61N1/3627 , A61N1/36514
摘要： Baroreflex activation is achieved by providing suitable control signals to a baroreflex activation device. A method comprises establishing a therapy interval (possibly on the order of minutes to hours, or possibly of indefinite duration), within the therapy interval, establishing a plurality of dose intervals, and generating an electrical output signal. The electrical output signal has a time dependence such that the average electrical power applied to the baroreflex activation device differs between first and second portions of at least some dose intervals. Another method comprises establishing a series of therapy interval portions, during at least some therapy intervals, establishing a plurality of burst intervals (perhaps having durations commensurate with an interval between heartbeats), and generating an electrical output signal. The electrical output signal has a time dependence such that the average electrical power applied to the baroreflex activation device differs between first and second portions of the therapy intervals and also differs between first and second portions of at least some burst intervals.
摘要翻译：通过向压力反射激活装置提供合适的控制信号来实现巴罗反射激活。一种方法包括在治疗间隔内建立治疗间隔（可能在数分钟到数小时，或者可能是不确定的持续时间），建立多个剂量间隔，以及产生电输出信号。电输出信号具有时间依赖性，使得施加到压力反射激活装置的平均电功率在至少一些剂量间隔的第一和第二部分之间不同。另一种方法包括在至少一些治疗间隔期间建立一系列治疗间隔部分，建立多个突发间隔（可能具有与心跳之间的间隔相当的持续时间），以及产生电输出信号。电输出信号具有时间依赖性，使得施加到压力反射激活装置的平均电功率在治疗间隔的第一和第二部分之间不同，并且在至少一些突发间隔的第一和第二部分之间也不同。

6. 发明申请

WO2005084389A3 EXTERNAL BAROREFLEX ACTIVATION 审中-公开
标题翻译：外部起搏器激活
公开(公告)号：WO2005084389A3
公开(公告)日：2006-11-16
申请号：PCT/US2005007237
申请日：2005-03-02
申请人： CVRX INC , KIEVAL ROBERT S , ROSSING MARTIN A
发明人： KIEVAL ROBERT S , ROSSING MARTIN A
IPC分类号： A61N1/04 , A61N1/05 , A61N1/36
CPC分类号： A61N1/36017 , A61N1/0556 , A61N1/36114
摘要： Methods and systems for external baroreflex activation allow a physician to characterize a patient's response to baroreflex activation prior to providing baroreflex activation therapy. Methods generally include applying a baroreflex activation stimulus to a patient, measuring one or more physiological parameters of the patient, and determining the extent to which the baroreflex activation causes a baroreflex response. Multiple stimuli of different intensities and/or from different locations may be compared. Systems include one or more external baroreflex activation devices (130) and one or more physiological parameter measuring devices (140). Optionally, a system may also include one or more fully or partially implantable devices for providing baroreflex activation therapy.
摘要翻译：用于外部压力反射激活的方法和系统允许医师在提供压力反射激活治疗之前表征患者对压力反射激活的反应。方法通常包括将压力反射激活刺激应用于患者，测量患者的一个或多个生理参数，以及确定压力反射激活导致压力反射反应的程度。可以比较不同强度和/或不同位置的多种刺激。系统包括一个或多个外部压力反射激活装置（130）和一个或多个生理参数测量装置（140）。任选地，系统还可以包括用于提供压力反射激活治疗的一个或多个完全或部分可植入装置。

7. 发明申请

WO2008083235A3 STIMULUS WAVEFORMS FOR BAROREFLEX ACTIVATION 审中-公开
标题翻译：刺激激活的刺激波形
公开(公告)号：WO2008083235A3
公开(公告)日：2008-09-04
申请号：PCT/US2007088974
申请日：2007-12-27
申请人： CVRX INC , CATES ADAM W , ROSSING MARTIN A
发明人： CATES ADAM W , ROSSING MARTIN A
IPC分类号： A61N1/02
CPC分类号： A61N1/0556 , A61N1/36114 , A61N1/36117
摘要： A method and apparatus for stimulation of a baroreflex system of a patient is provided. A method comprises establishing a therapy regimen including at least one pulse which includes at least two phases. Each phase has a polarity which is different than that of the other phase. The baroreflex system of the patient is activated with at least one baroreflex activation device which is responsive to the therapy regimen.
摘要翻译：提供了用于刺激患者的压力反射系统的方法和装置。一种方法包括建立包括至少一个包括至少两个相的脉冲的治疗方案。每相具有与另一相不同的极性。患者的压力反射系统通过响应于治疗方案的至少一个压力反射激活装置来激活。

8. 发明申请

WO2007114860A8 ELECTRODE STRUCTURES HAVING ANTI-INFLAMMATORY PROPERTIES AND METHODS OF USE 审中-公开
标题翻译：具有抗炎功能的电极结构和使用方法
公开(公告)号：WO2007114860A8
公开(公告)日：2008-08-07
申请号：PCT/US2006061256
申请日：2006-11-27
申请人： CVRX INC , ROSSING MARTIN A , KIEVAL ROBERT S , COLE MARY L
发明人： ROSSING MARTIN A , KIEVAL ROBERT S , COLE MARY L
IPC分类号： A61B5/04
CPC分类号： A61N1/05 , A61N1/0558 , A61N1/056 , A61N1/306
摘要： Electrode structures for implantation include an electrode, an elastic backing attached to the electrode, and a sequestered drug on the backing or the electrode which is released to control and/or limit the growth of scar tissue. The elastic backing includes a tissue contacting side which contacts a tissue structure, and an exposed side away from the tissue contacting side. The electrode structure can be used to activate baroreceptors, and the backing is elastic and can stretch and retract with the tissue structure, for example the carotid sinus. The electrode and the sequestered drug can be positioned on the tissue contacting side so the drug is released near the electrode. The backing can be made from an insulating material and limit diffusion of the drug toward the exposed side, permitting scar tissue to grow near the exposed side to maintain positioning of the electrode.
摘要翻译：用于植入的电极结构包括电极，附着到电极的弹性背衬和背衬或电极上的螯合药物，其被释放以控制和/或限制瘢痕组织的生长。弹性背衬包括接触组织结构的组织接触侧和远离组织接触侧的暴露侧。电极结构可用于激活压力感受器，并且背衬是弹性的并且可以与组织结构例如颈动脉窦一起伸展和缩回。电极和螯合药物可以定位在组织接触侧，因此药物在电极附近释放。背衬可以由绝缘材料制成并且限制药物朝向暴露侧的扩散，允许瘢痕组织在暴露侧附近生长以保持电极的定位。

9. 发明申请

WO2007118090A3 IMPLANTABLE EXTRAVASCULAR ELECTROSTIMULATION SYSTEM HAVING A RESILIENT CUFF 审中-公开
标题翻译：具有弹性模量的可植入的超静电电化学系统
公开(公告)号：WO2007118090A3
公开(公告)日：2008-11-06
申请号：PCT/US2007065880
申请日：2007-04-03
申请人： CVRX INC , ROSSING MARTIN A , COLE MARY L , SOLTIS BRIAN
发明人： ROSSING MARTIN A , COLE MARY L , SOLTIS BRIAN
IPC分类号： A61N1/05
CPC分类号： A61N1/05 , A61N1/0556
摘要： A method and device for providing stimulation to an artery for purposes of eliciting a physfalogic response. A cuff (100) having at least one electrode is provided, wherein the cuff is biased to conform to at least a portion of a vascular structure to maintain an intimate vascular structure-electrode interface. The device is selectively positioned proximate the effective position for providing stimulation to the vascular structure and the cuff is enabled to biasedly conform to at least a portion of the vascular structure. The cuff comprises includes resiliency enabling substantially normal pulsatile expansion of the artery while maintaining effective artery-electrode interface.
摘要翻译：为了引发生理反应的目的，为动脉提供刺激的方法和装置。提供具有至少一个电极的袖带（100），其中所述袖带被偏置以符合血管结构的至少一部分以维持紧密的血管结构 - 电极界面。选择性地将该装置定位在有效位置附近，以便向血管结构提供刺激，并且该袖带使得能够偏向地与至少一部分血管结构一致。袖带包括弹性，使得动脉实质上正常的脉动扩张同时保持有效的动脉 - 电极界面。

10. 发明申请

WO2007114860A3 ELECTRODE STRUCTURES HAVING ANTI-INFLAMMATORY PROPERTIES AND METHODS OF USE 审中-公开
标题翻译：具有抗炎功能的电极结构和使用方法
公开(公告)号：WO2007114860A3
公开(公告)日：2009-04-09
申请号：PCT/US2006061256
申请日：2006-11-27
申请人： CVRX INC , ROSSING MARTIN A , KIEVAL ROBERT S , COLE MARY L
发明人： ROSSING MARTIN A , KIEVAL ROBERT S , COLE MARY L
IPC分类号： A61B5/04
CPC分类号： A61N1/05 , A61N1/0558 , A61N1/056 , A61N1/306
摘要： Electrode structures for implantation include an electrode, an elastic backing attached to the electrode, and a sequestered drug on the backing or the electrode which is released to control and/or limit the growth of scar tissue. The elastic backing includes a tissue contacting side which contacts a tissue structure, and an exposed side away from the tissue contacting side. The electrode structure can be used to activate baroreceptors, and the backing is elastic and can stretch and retract with the tissue structure, for example the carotid sinus. The electrode and the sequestered drug can be positioned on the tissue contacting side so the drug is released near the electrode. The backing can be made from an insulating material and limit diffusion of the drug toward the exposed side, permitting scar tissue to grow near the exposed side to maintain positioning of the electrode.
摘要翻译：用于植入的电极结构包括电极，附着到电极的弹性背衬和背衬或电极上的螯合药物，其被释放以控制和/或限制瘢痕组织的生长。弹性背衬包括接触组织结构的组织接触侧和远离组织接触侧的暴露侧。电极结构可用于激活压力感受器，并且背衬是弹性的并且可以与组织结构例如颈动脉窦一起伸展和缩回。电极和螯合药物可以定位在组织接触侧，因此药物在电极附近释放。背衬可以由绝缘材料制成并且限制药物朝向暴露侧的扩散，允许瘢痕组织在暴露侧附近生长以保持电极的定位。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式