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1. 发明申请

WO2004024032A1 RETRIEVABLE FILTER 审中-公开
标题翻译：可检索过滤器
公开(公告)号：WO2004024032A1
公开(公告)日：2004-03-25
申请号：PCT/US2003/028679
申请日：2003-09-12
申请人： COOK INCORPORATED , WILLIAM COOK EUROPE APS
发明人： PAVCNIK, Dusan , CASE, Brian, C. , KAUFMAN, John, A. , GARRISON, Michael, L. , FLAGLE, Jacob, A.
IPC分类号： A61F2/01
CPC分类号： A61F2/01 , A61F2002/016 , A61F2230/005 , A61F2230/0067
摘要： A long-term retrievable, permanent blood filtration unit is to be implanted in a vessel of a patient's body, particularly for capturing blood clots, comprising a filter, a stent and a locking mechanism for releasably attaching the filter to the stent.
摘要翻译：将长期可回收的永久性血液过滤单元植入患者身体的容器中，特别是用于捕获血块，包括过滤器，支架和用于将过滤器可释放地附接到支架的锁定机构。

2. 发明申请

WO2004093745A1 DEVICES KITS, AND METHODS FOR PLACING MULTIPLE INTRALUMINAL MEDICAL DEVICES IN A BODY VESSEL 审中-公开
标题翻译：装置套件以及用于在身体容器中放置多个内部医疗装置的方法
公开(公告)号：WO2004093745A1
公开(公告)日：2004-11-04
申请号：PCT/US2004/012685
申请日：2004-04-23
申请人： COOK INCORPORATED , HOFFA, Andrew, K. , FLAGLE, Jacob, A. , GARRISON, Michael, L.
发明人： HOFFA, Andrew, K. , FLAGLE, Jacob, A. , GARRISON, Michael, L.
IPC分类号： A61F2/06
CPC分类号： A61F2/95 , A61F2/2412 , A61F2/2436 , A61F2/2475 , A61F2002/826
摘要： Devices, kits, and methods for delivering multiple intraluminal medical devices into a body vessel are provided.
摘要翻译：提供了将多个管腔内医疗装置输送到体内容器中的装置，试剂盒和方法。

3. 发明授权

EP1615593B1 INTRALUMINAL SUPPORT DEVICE WITH GRAFT 有权
标题翻译：与移植物INTRA LUMINALE支持装置
公开(公告)号：EP1615593B1
公开(公告)日：2010-01-06
申请号：EP04759192.0
申请日：2004-04-08
申请人： Cook Incorporated
发明人： CASE, Brian, C. , FLAGLE, Jacob, A. , PAUL, Ram, H. , HOFFA, Andrew, K. , GARRISON, Michael, L. , OBERMILLER, Joseph, F.
IPC分类号： A61F2/06 , A61F2/24
CPC分类号： A61F2/2475 , A61F2/2418 , A61F2/848 , A61F2220/0016 , A61F2220/005 , A61F2220/0058 , A61F2230/0026 , A61F2230/0054 , A61F2230/0095
摘要： Implantable medical devices comprising a support frame (710) and a graft member (718) attached to the support frame. The support frame can define one or more structural features (W1, W2) that substantially prevent migration of the graft member along the support frame.

4. 发明申请

WO2004096100A1 ARTIFICIAL VALVE PROSTHESIS WITH IMPROVED FLOW DYNAMICS 审中-公开
标题翻译：人工阀门改进流动动力学
公开(公告)号：WO2004096100A1
公开(公告)日：2004-11-11
申请号：PCT/US2004/012430
申请日：2004-04-21
申请人： COOK INCORPORATED , CASE, Brian, C. , FLAGLE, Jacob, A. , GARRISON, Michael, L. , HOFFA, Andrew, K. , SCHAEFFER, Darin, G.
发明人： CASE, Brian, C. , FLAGLE, Jacob, A. , GARRISON, Michael, L. , HOFFA, Andrew, K. , SCHAEFFER, Darin, G.
IPC分类号： A61F2/24
CPC分类号： A61F2/2418 , A61F2/2475 , A61F2002/068 , A61F2220/0008 , A61F2220/0016 , A61F2230/0054 , A61F2230/0076 , A61F2230/0078 , A61F2230/008 , A61F2250/0037 , A61F2250/0039
摘要： An expandable venous valve having a support structure (11) that configured to enlarge the area adjacent to the valve structure (12) such that the flow patterns of retrograde flow are modified in a way that facilitates the flushing of the pockets at the base of the valve area to prevent stagnation of bodily fluid, which in the venous system, can lead to thrombus formation. The enlarged pocket areas can be created by forming an artificial sinus (34) adjacent the valve structure in an unsupported section of vessel wall between two support frame section or the support frame can comprise an expanded-diameter intermediate or proximal section that forms an artificial sinus adjacent the valve structure. In another group of embodiments, the attachment pathway between opposing leaflets and the support frame and/or vessel wall comprises a proximal portion that places the leaflets in extended contact with one another and a distal portion forms a large angle with respect to the adjacent walls such that a large pocket is created at the base of the leaflets. In one embodiment, the attachment pathway extends distally along a pair of substantially parallel longitudinal attachment struts to create an extended leaflet contact area, then angles circumferentially and distally from the former along distal attachment struts to define the bottom edge of the leaflets.
摘要翻译：一种具有支撑结构（11）的可膨胀静脉瓣，所述支撑结构（11）构造成扩大邻近所述瓣膜结构（12）的区域，使得逆行流的流动模式被改变为有利于在阀门区域，以防止静脉系统中的体液停滞，可导致血栓形成。可以通过在两个支撑框架部分之间的血管壁的无支撑部分中形成邻近阀结构的人造窦（34）来产生扩大的口袋区域，或者支撑框架可以包括形成人造窦的扩张直径的中间或近端部分邻近阀门结构。在另一组实施例中，相对的小叶和支撑框架和/或血管壁之间的附接通路包括近端部分，其将小叶彼此延伸接触，并且远端部分相对于相邻壁形成大角度，在传单的底部创造了一个大口袋。在一个实施例中，附接通道沿着一对基本上平行的纵向连接支柱向远侧延伸以产生延伸的小叶接触区域，然后沿着远侧连接支柱周向地和远端地从前者角度定位以限定传单的底部边缘。

5. 发明申请

WO2004082530A2 DELIVERY SYSTEMS AND METHODS FOR DEPLOYING EXPANDABLE INTRALUMINAL MEDICAL DEVICES 审中-公开
标题翻译：用于配置可扩展的内镜医疗装置的递送系统和方法
公开(公告)号：WO2004082530A2
公开(公告)日：2004-09-30
申请号：PCT/US2004/008507
申请日：2004-03-19
申请人： COOK INCORPORATED , GARRISON, Michael, L. , CASE, Brian, C. , HOFFA, Andrew, K. , FLAGLE, Jacob, A. , PAVCNIK, Dusan
发明人： GARRISON, Michael, L. , CASE, Brian, C. , HOFFA, Andrew, K. , FLAGLE, Jacob, A. , PAVCNIK, Dusan
IPC分类号： A61F
CPC分类号： A61F2/95 , A61F2/013 , A61F2/966 , A61F2002/011 , A61F2002/015 , A61F2230/0006 , A61F2230/005
摘要： Methods and devices for delivering and deploying expandable intraluminal medical devices at a desired point of treatment within a body vessel are provided. A portion of a delivery device is spaced from an interior wall surface of the body vessel prior to deployment of the expandable intraluminal device.
摘要翻译：提供了用于在体内容器内的期望治疗点递送和部署可膨胀管腔内医疗装置的方法和装置。在部署可膨胀的管腔内装置之前，输送装置的一部分与身体血管的内壁表面间隔开。

6. 发明申请

WO2004075789A3 PROTHESIS ADAPTED FOR PLACEDd UNDER EXTERNAL IMAGING 审中-公开
公开(公告)号：WO2004075789A3
公开(公告)日：2004-09-10
申请号：PCT/US2004/005750
申请日：2004-02-26
申请人： COOK INCORPORATED , CASE, Brian, C. , FLAGLE, Jacob, A. , GARRISON, Michael, L. , HOFFA, Andrew, K. , LEONARD, Ray, II
发明人： CASE, Brian, C. , FLAGLE, Jacob, A. , GARRISON, Michael, L. , HOFFA, Andrew, K. , LEONARD, Ray, II
IPC分类号： A61F2/06
摘要： A expandable prosthesis having an imageable structure (12) comprising one or more elements (13, 14) visually distinguishable by an external (e.g., radiographic or ultrasonic) imaging system (91), the structure being located about a first axis (97) that corresponds to a structural feature (24, 82) of the prosthesis that is configured to perform a specific function particular to that axis. The imageable structure is configured to assist in the rotational orientation of the prosthesis during placement within the implantation site. In one embodiment the prosthesis comprises a venous valve that includes imageable elements or structure, such as a pair of radiopaque markers, that defines the orifice of the valve structure such that the orifice can be oriented with a particular anatomical feature under imaging, such as to align the orifice with the long axis of the vessel. In another embodiment, the imageable structure is configured to permit an aperture located about a stent graft to be oriented with a anatomical feature of the vessel, such as a branch vessel opening

7. 发明公开

EP1626681A1 IMPLANTABLE MEDICAL DEVICE WITH CONSTRAINED EXPANSION 有权
标题翻译：植入式医疗设备临时扩展
公开(公告)号：EP1626681A1
公开(公告)日：2006-02-22
申请号：EP04752669.4
申请日：2004-05-19
申请人： Cook Incorporated
发明人： OSBORNE, Thomas, A. , CASE, Brian, C. , FLAGLE, Jacob, A. , HOFFA, Andrew, K. , GARRISON, Michael, L.
IPC分类号： A61F2/24
CPC分类号： A61F2/2418 , A61F2/2475 , A61F2220/0008 , A61F2220/0016 , A61F2220/0075 , A61F2230/0026 , A61F2230/0095
摘要： Medical devices for implantation in a body vessel are provided. A medical device according to the invention comprises a support structure and one or more graft members comprising a valve portion and a constraining portion. The support structure has a first, unexpanded configuration and a second, expanded configuration. The constraining portion is adapted to substantially prevent the support structure from achieving the second, expanded configuration. The valve portion is adapted to permit fluid flow through a body vessel in a first direction and substantially prevent fluid flow through the vessel in a second, opposite direction.

8. 发明申请

WO2006050460A1 VASCULAR VALVES HAVING IMPLANTED AND TARGET CONFIGURATIONS AND METHODS OF PREPARING THE SAME 审中-公开
标题翻译：具有植入物和目标配置的血管瓣及其制备方法
公开(公告)号：WO2006050460A1
公开(公告)日：2006-05-11
申请号：PCT/US2005/039835
申请日：2005-10-27
申请人： COOK INCORPORATED , CASE, Brian, C. , FLAGLE, Jacob, A. , GARRISON, Michael, L. , OBERMILLER, F., Joseph , PAVCNIK, Dusan
发明人： CASE, Brian, C. , FLAGLE, Jacob, A. , GARRISON, Michael, L. , OBERMILLER, F., Joseph , PAVCNIK, Dusan
IPC分类号： A61F2/24
CPC分类号： A61F2/2418 , A61F2/2436 , A61F2/2475 , A61F2210/0004 , A61F2220/0016 , A61F2250/0067
摘要： Described are vascular valve devices for implantation in a patient. The vascular valve devices are designed to compensate for the retraction characteristics of a remodelable material used to form one or more leaflets. Alternatively, or in addition, the devices are designed to reduce retraction of the remodelable leaflet-forming material. Further described are methods for preparing and using these vascular valve devices.
摘要翻译：描述了用于植入患者体内的血管瓣膜装置。血管瓣膜装置被设计成补偿用于形成一个或多个传单的可重塑材料的回缩特性。或者或另外，设备被设计成减少可重塑的小叶形成材料的缩回。进一步描述了制备和使用这些血管瓣膜装置的方法。

9. 发明申请

WO2005107646A1 DELIVERY SYSTEM THAT FACILITATES VISUAL INSPECTION OF AN INTRALUMINAL MEDICAL DEVICE 审中-公开
标题翻译：有助于视觉检查医疗器械的输送系统
公开(公告)号：WO2005107646A1
公开(公告)日：2005-11-17
申请号：PCT/US2005/016109
申请日：2005-05-06
申请人： COOK INCORPORATED , FLAGLE, Jacob, A. , CASE, Brian, C. , HOFFA, Andrew, K. , GARRISON, Michael, L.
发明人： FLAGLE, Jacob, A. , CASE, Brian, C. , HOFFA, Andrew, K. , GARRISON, Michael, L.
IPC分类号： A61F2/06
CPC分类号： A61M25/0043 , A61F2/95 , A61F2250/0091 , A61M25/10 , A61M2025/1079
摘要： Delivery systems, methods of making delivery systems, and methods of treatment are provided. A delivery system according to the invention facilitates a visual inspection of an intraluminal medical device included in the delivery system.
摘要翻译：提供交付系统，交付系统的方法和处理方法。根据本发明的递送系统便于对包括在递送系统中的管腔内医疗装置的目视检查。

10. 发明申请

WO2004103222A1 IMPLANTABLE MEDICAL DEVICE WITH CONSTRAINED EXPANSION 审中-公开
标题翻译：具有约束扩张的可植入医疗装置
公开(公告)号：WO2004103222A1
公开(公告)日：2004-12-02
申请号：PCT/US2004/015692
申请日：2004-05-19
申请人： COOK INCORPORATED , OSBORNE, Thomas, A. , CASE, Brian, C. , FLAGLE, Jacob, A. , HOFFA, Andrew, K. , GARRISON, Michael, L.
发明人： OSBORNE, Thomas, A. , CASE, Brian, C. , FLAGLE, Jacob, A. , HOFFA, Andrew, K. , GARRISON, Michael, L.
IPC分类号： A61F2/24
CPC分类号： A61F2/2418 , A61F2/2475 , A61F2220/0008 , A61F2220/0016 , A61F2220/0075 , A61F2230/0026 , A61F2230/0095
摘要： Medical devices for implantation in a body vessel are provided. A medical device according to the invention comprises a support structure and one or more graft members comprising a valve portion and a constraining portion. The support structure has a first, unexpanded configuration and a second, expanded configuration. The constraining portion is adapted to substantially prevent the support structure from achieving the second, expanded configuration. The valve portion is adapted to permit fluid flow through a body vessel in a first direction and substantially prevent fluid flow through the vessel in a second, opposite direction.
摘要翻译：提供用于植入体内的医疗装置。根据本发明的医疗装置包括支撑结构和包括阀部分和约束部分的一个或多个移植部件。支撑结构具有第一，未膨胀的构造和第二扩展构型。约束部分适于基本上防止支撑结构实现第二扩张构型。阀部分适于允许流体沿第一方向流过身体容器，并且基本上防止流体沿第二相反方向流过血管。

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