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1. 发明公开

EP0821590A1 LARGE AREA SUBMUCOSAL GRAFT CONSTRUCTS AND METHOD FOR MAKING THE SAME 失效
标题翻译：粘膜下组织和方法大面积移植物及其制备
公开(公告)号：EP0821590A1
公开(公告)日：1998-02-04
申请号：EP96912588.0
申请日：1996-04-05
申请人： Patel, Umesh H. , Hiles, Michael C. , Whitson, Bryan A. , Cheng, Boyle , Badylak, Stephen F. , Kokini, Klod , Methodist Health Group, Inc. , PURDUE RESEARCH FOUNDATION
发明人： Patel, Umesh H. , Hiles, Michael C. , Whitson, Bryan A. , Cheng, Boyle , Badylak, Stephen F. , Kokini, Klod , Methodist Health Group, Inc. , PURDUE RESEARCH FOUNDATION
IPC分类号： A61L27 , A61F2 , A61K35 , A61P43
CPC分类号： A61L27/3691 , A61F2/0063 , A61K35/38 , A61L27/3629
摘要： A unitary heterolaminar tissue graft construct is prepared by fusing partially overlapped strips or sheets of submucosa tissue. The submucosa components are fused by compressing at least the overlapped positions of said strips between two surfaces under conditions that allow or promote dehydration of the compressed submucosa sheets. Three dimensional graft constructs can be prepared by using complementary non-planar compressive surfaces.

2. 发明公开

EP1051116A1 EMBOLIZATION DEVICE 有权
标题翻译： DEVICE帧内血管栓塞
公开(公告)号：EP1051116A1
公开(公告)日：2000-11-15
申请号：EP99961829.1
申请日：1999-11-24
申请人： WASHINGTON UNIVERSITY , Cook Biotech, Inc. , MED INSTITUTE, INC. , MORAN, Christopher J. , Bleyer, Mark W. , Kozma, Thomas G. , Patel, Umesh H.
发明人： MORAN, Christopher, J., M., D. , BLEYER, Mark, W. , KOZMA, Thomas, G. , PATEL, Umesh, H.
IPC分类号： A61B17/12 , A61L31/00
CPC分类号： A61K35/38 , A61B17/12022 , A61B17/12109 , A61B17/12113 , A61B17/1214 , A61B17/12145 , A61B17/1215 , A61B17/12163 , A61B17/12168 , A61B17/12172 , A61B17/12181 , A61B17/1219 , A61B90/39 , A61L31/005 , A61L31/18 , A61L2430/36
摘要： A medical device (40) including a collagenous biomaterial (10) for causing embolus and treating an aneurysm. The collagenous biomaterial (10) includes a small intestine submucosa (12) that is configured into various components (16) for causing a vascular occlusion or a packing aneurysm lumen.

3. 发明授权

EP1051116B1 EMBOLIZATION DEVICE 有权
标题翻译： DEVICE帧内血管栓塞
公开(公告)号：EP1051116B1
公开(公告)日：2008-10-08
申请号：EP99961829.1
申请日：1999-11-24
申请人： Washington University , Cook Biotech, Inc. , Med Institute, Inc. , Moran, Christopher J., M. D. , Bleyer, Mark W. , Kozma, Thomas G. , Patel, Umesh H.
发明人： MORAN, Christopher, J., M., D. , BLEYER, Mark, W. , KOZMA, Thomas, G. , PATEL, Umesh, H.
IPC分类号： A61B17/12 , A61L31/00
CPC分类号： A61K35/38 , A61B17/12022 , A61B17/12109 , A61B17/12113 , A61B17/1214 , A61B17/12145 , A61B17/1215 , A61B17/12163 , A61B17/12168 , A61B17/12172 , A61B17/12181 , A61B17/1219 , A61B90/39 , A61L31/005 , A61L31/18 , A61L2430/36
摘要： A medical device (40) including a collagenous biomaterial (10) for causing embolus and treating an aneurysm. The collagenous biomaterial (10) includes a small intestine submucosa (12) that is configured into various components (16) for causing a vascular occlusion or a packing aneurysm lumen.

4. 发明专利

DE69939685D1 未知
公开(公告)号：DE69939685D1
公开(公告)日：2008-11-20
申请号：DE69939685
申请日：1999-11-24
申请人： UNIV WASHINGTON , COOK BIOTECH INC , MED INST INC , MORAN CHRISTOPHER J , BLEYER MARK W , KOZMA THOMAS G , PATEL UMESH H
发明人： MORAN CHRISTOPHER J , BLEYER MARK W , KOZMA THOMAS G , PATEL UMESH H
IPC分类号： A61B17/12 , A61B19/00 , A61K35/38 , A61L27/36 , A61L31/00
摘要： A medical device (40) including a collagenous biomaterial (10) for causing embolus and treating an aneurysm. The collagenous biomaterial (10) includes a small intestine submucosa (12) that is configured into various components (16) for causing a vascular occlusion or a packing aneurysm lumen.

5. 发明专利

AT410119T 未知
公开(公告)号：AT410119T
公开(公告)日：2008-10-15
申请号：AT99961829
申请日：1999-11-24
申请人： UNIV WASHINGTON , COOK BIOTECH INC , MED INST INC , MORAN CHRISTOPHER J M D , BLEYER MARK W , KOZMA THOMAS G , PATEL UMESH H
发明人： MORAN CHRISTOPHER , BLEYER MARK , KOZMA THOMAS , PATEL UMESH
IPC分类号： A61B17/12 , A61B19/00 , A61K35/38 , A61L27/36 , A61L31/00
摘要： A medical device (40) including a collagenous biomaterial (10) for causing embolus and treating an aneurysm. The collagenous biomaterial (10) includes a small intestine submucosa (12) that is configured into various components (16) for causing a vascular occlusion or a packing aneurysm lumen.

6. 发明专利

AU1832700A Embolization device 未知
公开(公告)号：AU1832700A
公开(公告)日：2000-06-19
申请号：AU1832700
申请日：1999-11-24
申请人： BLEYER MARK W , COOK BIOTECH INC , KOZMA THOMAS G , MED INSTITUTE INC , MORAN CHRISTOPHER J M D , PATEL UMESH H , UNIV WASHINGTON
发明人： MORAN CHRISTOPHER J M D , BLEYER MARK W , KOZMA THOMAS G , PATEL UMESH H
IPC分类号： A61B17/12 , A61B19/00 , A61K35/38 , A61L27/36 , A61L31/00
摘要： A medical device (40) including a collagenous biomaterial (10) for causing embolus and treating an aneurysm. The collagenous biomaterial (10) includes a small intestine submucosa (12) that is configured into various components (16) for causing a vascular occlusion or a packing aneurysm lumen.

7. 发明申请

WO2010088678A3 MEDICAL BEAD PRODUCTS 审中-公开
标题翻译：医用珠品
公开(公告)号：WO2010088678A3
公开(公告)日：2011-01-20
申请号：PCT/US2010022910
申请日：2010-02-02
申请人： COOK BIOTECH INC , PATEL UMESH H , YESTREPSKY ADAM
发明人： PATEL UMESH H , YESTREPSKY ADAM
IPC分类号： A61L27/36 , A61L27/54
CPC分类号： A61L27/3633 , A61L27/54 , A61L2300/236 , A61L2300/252 , A61L2300/414 , A61L2300/416 , A61L2300/45 , A61L2300/622
摘要： Described, in certain aspects, are medical bead products including an extracellular matrix (ECM) bead comprised of reconstituted biotropic ECM material. Such an ECM bead can have a generally homogeneous network of self- assembled collagen fibers, and comprise at least one bioactive agent retained in the ECM material, wherein the bioactive agent is selected from the group consisting of a proteoglycan, a growth factor, a glycoprotein, and a glycosaminoglycan. In some forms, the ECM bead further comprises at least one additional bioactive agent disposed thereon, for example, a pharmaceutical such as an antineoplastic agent. Preferably, the ECM material comprises submucosa, for example, porcine small intestinal submucosa (SIS).
摘要翻译：在某些方面描述了医疗珠粒产品，包括由重构的生物力ECM材料组成的细胞外基质（ECM）珠粒。这样的ECM珠可以具有大体上均匀的自组装胶原纤维网，并且包含保留在ECM材料中的至少一种生物活性剂，其中生物活性剂选自蛋白多糖，生长因子，糖蛋白和糖胺聚糖。在一些形式中，ECM珠还包含至少一种另外的置于其上的生物活性剂，例如药物如抗肿瘤剂。优选地，ECM材料包括粘膜下层，例如猪小肠粘膜下层（SIS）。

8. 发明申请

WO2009086499A3 MEDICAL COMPOSITION INCLUDING AN EXTRACELLULAR MATRIX PARTICULATE 审中-公开
标题翻译：包括细胞基质颗粒的医学成分
公开(公告)号：WO2009086499A3
公开(公告)日：2010-04-15
申请号：PCT/US2008088406
申请日：2008-12-29
申请人： COOK BIOTECH INC , HOODE JASON P , PATEL UMESH H
发明人： HOODE JASON P , PATEL UMESH H
IPC分类号： A61L15/40 , A61L15/44 , A61L26/00
CPC分类号： A61L15/40 , A61L15/44 , A61L26/0057 , A61L26/0066 , A61L2300/104 , A61L2300/258 , A61L2300/404 , A61L2300/414 , A61L2300/622
摘要： Described are medical compositions including a collagenous ECM particulate dispersed in a carrier. Such medical compositions can be applied to at least a portion of a surface of a sheet of collagenous ECM material to form a medical product. Medical compositions and products as described herein find particular use in wound repair. Related methods of manufacture and use are also described.
摘要翻译：描述了包括分散在载体中的胶原性ECM颗粒的药物组合物。这样的医用组合物可以应用于胶原性ECM材料片材的至少一部分表面以形成医疗产品。如本文所述的医疗组合物和产品在伤口修复中特别有用。还描述了相关的制造和使用方法。

9. 发明申请

WO2009146369A1 DEVICES AND METHODS FOR TREATING RECTOVAGINAL AND OTHER FISTULAE 审中-公开
标题翻译：用于治疗重建和其他造影剂的装置和方法
公开(公告)号：WO2009146369A1
公开(公告)日：2009-12-03
申请号：PCT/US2009/045467
申请日：2009-05-28
申请人： COOK BIOTECH INCORPORATED , PATEL, Umesh, H. , OBERMILLER, F., Joseph
发明人： PATEL, Umesh, H. , OBERMILLER, F., Joseph
IPC分类号： A61B17/00
CPC分类号： A61B17/0057 , A61B2017/00004 , A61B2017/00641
摘要： Provided by certain aspects of the invention are methods for treating fistulae and various fistula graft assemblages useful in this regard. Illustratively, some inventive methods are useful in treating fistulae having at least a first fistula opening, a second fistula opening and a fistula tract extending therebetween. In one step, a first capping member is positioned over the first fistula opening such that a first pulling member, which extends from the first capping member, passes through the fistula tract. In another step, a second capping member is positioned over the second fistula opening such that a second pulling member, which extends from the second capping member, passes through the fistula tract. A first pulling force is applied to the first pulling member, and a second pulling force is applied to the second pulling member, for maintaining the first capping member over the first fistula opening and for maintaining the second capping member over the second fistula opening, respectively.
摘要翻译：由本发明的某些方面提供的是用于治疗瘘管和各种瘘移植物组合物的方法。说明性地，一些本发明的方法可用于治疗具有至少第一瘘开口，第二瘘开口和在其间延伸的瘘管道的瘘。在一个步骤中，第一封盖构件定位在第一瘘开口上方，使得从第一封盖构件延伸的第一牵引构件穿过瘘管道。在另一步骤中，第二封盖构件定位在第二瘘开口上方，使得从第二封盖构件延伸的第二牵引构件穿过瘘管道。第一拉力被施加到第一牵引构件，并且第二拉力施加到第二牵引构件，用于将第一封盖构件保持在第一瘘开口上方并且用于将第二封盖构件分别保持在第二瘘开口上方。

10. 发明申请

WO2008112627A2 SYSTEM AND METHOD FOR PROVIDING LOCATION-BASED TRAINING INFORMATION 审中-公开
标题翻译：用于提供基于位置的培训信息的系统和方法
公开(公告)号：WO2008112627A2
公开(公告)日：2008-09-18
申请号：PCT/US2008056399
申请日：2008-03-10
申请人： HONEYWELL INT INC , PATEL UMESH J
发明人： PATEL UMESH J
IPC分类号： H04Q7/00
CPC分类号： G06Q10/06 , G09B7/00 , H04L67/18 , H04L67/28
摘要： Training information can be presented to a person (102a-102n) based on that person's location. For example, a wireless device (108a-108n) used by an employee or trainee can receive and present training information (such as an audio or video program) based on his or her location in an industrial facility or complex. The person's location can be tracked in any suitable manner, such as by using GPS, RFID, or other tracking technology. The person's location can also be determined at the wireless device (108a-108n) or by an external system, such as the system providing the training information. When the person (102a-102n) enters a particular area, such as a specified training area in an industrial facility or complex, the person's wireless device (108a-108n) can receive training information tailored to that particular area of the industrial facility or complex.
摘要翻译：培训信息可以根据该人的位置呈现给一个人（102a-102n）。例如，雇员或受训者使用的无线设备（108a-108n）可以基于他或她在工业设施或复合体中的位置来接收和呈现培训信息（诸如音频或视频节目）。可以以任何合适的方式跟踪人员的位置，例如使用GPS，RFID或其他跟踪技术。也可以在无线设备（108a-108n）或外部系统（例如提供训练信息的系统）确定该人的位置。当人（102a-102n）进入工业设施或综合体中的指定训练区域的特定区域时，该人的无线设备（108a-108n）可以接收针对工业设施或复合体的该特定区域定制的训练信息。

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