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1. 发明申请

WO2008034914A2 A DISPENSER DEVICE FOR AND A METHOD OF DISPENSING A SUBSTANCE ONTO A SUBSTRATE 审中-公开
标题翻译：一种用于将物质分配到基板上的分配器装置和方法
公开(公告)号：WO2008034914A2
公开(公告)日：2008-03-27
申请号：PCT/EP2007/060129
申请日：2007-09-24
申请人： CLONDIAG GMBH , ERMANTRAUT, Eugen , SCHULZ, Torsten , FISCHER, Joachim , WEICHERDING, Daniel , POSER, Siegfried , KIRST, Matthias
发明人： ERMANTRAUT, Eugen , SCHULZ, Torsten , FISCHER, Joachim , WEICHERDING, Daniel , POSER, Siegfried , KIRST, Matthias
IPC分类号： G01N35/10
CPC分类号： G01N35/1011 , G01N35/028 , G01N35/109 , G01N2001/4027 , G01N2035/00158 , G01N2035/1037 , G01N2035/1039
摘要： A dispenser device (100) for dispensing a substance (101) onto a substrate (102), the dispenser device (100) comprising a gripper unit (103) adapted for gripping a container (104) including the substance (101), a first motion mechanism (116, 117) adapted for moving the gripper unit (103) and the substrate (102) relative to each other within a planar region (106), and a second motion mechanism (115, 201 to 209) adapted for moving the gripper unit (103) and the substrate (102) relative to each other in a direction (108) essentially perpendicular to the planar region (106) to thereby dispense the substance (101) to a surface portion (109) of the substrate (102), wherein the first motion mechanism (115) and the second motion mechanism (116, 117) are decoupled from one another.
摘要翻译：一种用于将物质（101）分配到衬底（102）上的分配装置（100），所述分配装置（100）包括适于夹持容器（104）的夹具单元（103），所述夹具单元包括所述物质（101），适于在平面区域（106）内相对于彼此移动所述夹持器单元（103）和所述衬底（102）的第一运动机构（116,117），以及第二运动机构 201），其适于在基本上垂直于平面区域（106）的方向（108）上相对于彼此移动夹具单元（103）和衬底（102），从而将物质（101）分配到表面部分（102）的第一运动机构（109），其中第一运动机构（115）和第二运动机构（116,117）彼此分离。

2. 发明申请

WO2008046930A1 ASSAY DEVICES AND METHODS FOR THE DETECTION OF ANALYTES 审中-公开
标题翻译：用于检测分析物的测定装置和方法
公开(公告)号：WO2008046930A1
公开(公告)日：2008-04-24
申请号：PCT/EP2007/061302
申请日：2007-10-22
申请人： CLONDIAG GMBH , ERMANTRAUT, Eugen , SCHULZ, Torsten , ELLINGER, Thomas , WEICHERDING, Daniel
发明人： ERMANTRAUT, Eugen , SCHULZ, Torsten , ELLINGER, Thomas , WEICHERDING, Daniel
IPC分类号： G01N21/64 , B01L3/00
CPC分类号： B01L3/502707 , B01L2300/0636 , B01L2300/069 , B01L2300/0877 , B01L2400/0481 , C12Q1/6834
摘要： The present invention relates to devices and methods for performing assays, especially for determining the presence and/or amount of one or more analytes. In particular, the invention relates to a device for the detection of analytes, comprising a reversibly compressible matrix located between a first surface and a second surface, wherein the second surface is located opposite to the first surface, and wherein the distance between the first surface and the second surface is variable. The invention also relates to a corresponding method using such a device for the detection of one or more species of analytes.
摘要翻译：本发明涉及用于进行测定的装置和方法，特别是用于确定一种或多种分析物的存在和/或量。特别地，本发明涉及用于检测分析物的装置，包括位于第一表面和第二表面之间的可逆压缩基质，其中第二表面位于与第一表面相对的位置，并且其中第一表面并且第二表面是可变的。本发明还涉及使用这种装置用于检测一种或多种分析物的相应方法。

3. 发明申请

WO2006056466A2 VERFAHREN ZUR ORTSSPEZIFISCHEN SYNTHESE VON BIOPOLYMEREN AUF FESTEN TRÄGERN 审中-公开
标题翻译：程序的生物聚合物在固体载体上局部特定合成
公开(公告)号：WO2006056466A2
公开(公告)日：2006-06-01
申请号：PCT/EP2005/012648
申请日：2005-11-25
申请人： CLONDIAG CHIP TECHNOLOGIES GMBH , ELLINGER, Thomas , ERMANTRAUT, Eugen , HOLZHEY, Nancy , PLENZ, Frank , SCHULZ, Torsten , TUCHSCHEERER, Jens , WEICHERDING, Daniel
发明人： ELLINGER, Thomas , ERMANTRAUT, Eugen , HOLZHEY, Nancy , PLENZ, Frank , SCHULZ, Torsten , TUCHSCHEERER, Jens , WEICHERDING, Daniel
CPC分类号： B82Y30/00 , B01J19/0046 , B01J2219/0043 , B01J2219/00659 , B01J2219/00662 , B01J2219/00675 , B01J2219/00722 , B01J2219/00725 , C40B40/06 , C40B40/10 , C40B50/14 , C40B60/14
摘要： Die Erfindung betrifft Verfahren zur ortsspezifischen Synthese von Biopolymeren wie Nukleinsäuren oder Peptiden und deren jeweiligen Derivaten auf festen Trägern, wobei die örtliche Diskriminierung der Synthese insbesondere durch Verwendung von Masken erfolgt, die wässrige Aktivierungsreagenzien für die Abspaltung von Schutzgruppen zu vorbestimmten Bereichen auf dem Träger führen.
摘要翻译：本发明涉及一种用于生物聚合物的位点特异性的合成方法，如核酸或肽和在固体载体上，其中所述合成的本地鉴别特别是通过使用掩模的情况下进行其各自的衍生物，例如，使得所述水性活化试剂用于除去保护基团，以预定区域在载体上。

4. 发明申请

WO2012072795A2 TRANSFORMATION OF MATERIAL INTO AN OPTICALLY MODULATING STATE VIA LASER RADIATION 审中-公开
标题翻译：通过激光辐射将材料转变为光调制状态
公开(公告)号：WO2012072795A2
公开(公告)日：2012-06-07
申请号：PCT/EP2011/071618
申请日：2011-12-02
申请人： ALERE TECHNOLOGIES GMBH , SCHULZ, Torsten , WEICHERDING, Daniel
发明人： SCHULZ, Torsten , WEICHERDING, Daniel
IPC分类号： B01L3/00 , G02C7/02
CPC分类号： G01N21/6402 , B01L3/502707 , B01L2300/0654 , B01L2300/168 , B41M5/24 , B41M5/26 , B41M5/267 , G02C7/021
摘要： A method for the transformation of material (e.g. plastic material) into an optically modulating state via laser radiation is described. The optically modulating state may be a state in which light is emitted at a different wavelength than it is absorbed. The plastic material to may be a thermoplastic or elastomeric material, or an organic polymer selected from the group consisting of polyethylene, polypropylene, polystyrene, polycarbonate and polycycloolefin. The laser radiation may comprise the application of an amount of energy of about 0.1 nJoule/μm 2 to about 100 μJoule/μm 2 and/or may comprise a radiation of a wavelength of about 355 nm to about 1064 nm. The optically modulating state of the plastic material may absorb light in a wavelength spectrum of about 380 nm to about 540 nm and/or a wavelength spectrum of about 635 nm to about 655 nm. The optically modulating state of the plastic material may emit light in a wavelength spectrum of about 550 nm to about 800 nm. The transformation of the plastic material may comprise the generation of optically modulating elements on the surface of said plastic material, selected from the group comprising geometrical forms, geometrical pattern, spots, dots, lines, circles, squares, characters, symbols, drawings, barcode and datamatrixcode. The material may be used as component for the manufacture of a device, microfluidic device, system, cartridge or instrument. Based on the employment of the material the usability of a device or system and/or of any procedure, function or method carried out with it or in it may be determined and/or controlled.
摘要翻译：描述了一种用于通过激光辐射将材料（例如塑料材料）转换成光学调制状态的方法。光调制状态可以是其中光以不同于被吸收的波长发射的状态。塑料材料可以是热塑性或弹性材料，或选自聚乙烯，聚丙烯，聚苯乙烯，聚碳酸酯和聚环烯烃的有机聚合物。激光辐射可以包括施加大约0.1nJoule /μm2到大约100μJoule/μm2的能量和/或可以包括波长的辐射约355nm至约1064nm。塑料材料的光学调制状态可以吸收约380nm至约540nm的波长谱和/或约635nm至约655nm的波长谱的光。塑料材料的光调制状态可以发射约550nm至约800nm的波长光谱的光。塑料材料的变换可以包括在所述塑料材料的表面上产生光调制元件，所述光调制元件选自包括几何形状，几何图案，点，点，线，圆，正方形，字符，符号，图形，条形码和数据矩阵码。该材料可以用作制造装置，微流体装置，系统，药筒或仪器的部件。基于材料的使用，可以确定和/或控制装置或系统的可用性和/或与其一起或在其中执行的任何过程，功能或方法的可用性。

5. 发明公开

EP2078189A1 ASSAY DEVICES AND METHODS FOR THE DETECTION OF ANALYTES 有权
标题翻译：测试设备和检测方法的分析物
公开(公告)号：EP2078189A1
公开(公告)日：2009-07-15
申请号：EP07821666.0
申请日：2007-10-22
申请人： Clondiag GmbH
发明人： ERMANTRAUT, Eugen , SCHULZ, Torsten , ELLINGER, Thomas , WEICHERDING, Daniel
IPC分类号： G01N21/64 , B01L3/00
CPC分类号： B01L3/502707 , B01L2300/0636 , B01L2300/069 , B01L2300/0877 , B01L2400/0481 , C12Q1/6834
摘要： The present invention relates to devices and methods for performing assays, especially for determining the presence and/or amount of one or more analytes. In particular, the invention relates to a device for the detection of analytes, comprising a reversibly compressible matrix located between a first surface and a second surface, wherein the second surface is located opposite to the first surface, and wherein the distance between the first surface and the second surface is variable. The invention also relates to a corresponding method using such a device for the detection of one or more species of analytes.

6. 发明公开

EP2064557A2 A DISPENSER DEVICE FOR AND A METHOD OF DISPENSING A SUBSTANCE ONTO A SUBSTRATE 有权
标题翻译：供给部件及方法可使物质到基板
公开(公告)号：EP2064557A2
公开(公告)日：2009-06-03
申请号：EP07820535.8
申请日：2007-09-24
申请人： Clondiag GmbH
发明人： ERMANTRAUT, Eugen , SCHULZ, Torsten , FISCHER, Joachim , WEICHERDING, Daniel , POSER, Siegfried , KIRST, Matthias
IPC分类号： G01N35/10 , G01N35/00 , G01N35/02
CPC分类号： G01N35/1011 , G01N35/028 , G01N35/109 , G01N2001/4027 , G01N2035/00158 , G01N2035/1037 , G01N2035/1039
摘要： A dispenser device (100) for dispensing a substance (101) onto a substrate (102), the dispenser device (100) comprising a gripper unit (103) adapted for gripping a container (104) including the substance (101), a first motion mechanism (116, 117) adapted for moving the gripper unit (103) and the substrate (102) relative to each other within a planar region (106), and a second motion mechanism (115, 201 to 209) adapted for moving the gripper unit (103) and the substrate (102) relative to each other in a direction (108) essentially perpendicular to the planar region (106) to thereby dispense the substance (101) to a surface portion (109) of the substrate (102), wherein the first motion mechanism (115) and the second motion mechanism (116, 117) are decoupled from one another.

7. 发明授权

EP2064557B1 A DISPENSER DEVICE FOR AND A METHOD OF DISPENSING A SUBSTANCE ONTO A SUBSTRATE 有权
标题翻译：供给部件及方法可使物质到基板
公开(公告)号：EP2064557B1
公开(公告)日：2015-09-16
申请号：EP07820535.8
申请日：2007-09-24
申请人： Clondiag GmbH
发明人： ERMANTRAUT, Eugen , SCHULZ, Torsten , FISCHER, Joachim , WEICHERDING, Daniel , POSER, Siegfried , KIRST, Matthias
IPC分类号： G01N35/10 , G01N35/00 , G01N35/02
CPC分类号： G01N35/1011 , G01N35/028 , G01N35/109 , G01N2001/4027 , G01N2035/00158 , G01N2035/1037 , G01N2035/1039

8. 发明授权

EP1814656B1 VERFAHREN ZUR ORTSSPEZIFISCHEN SYNTHESE VON BIOPOLYMEREN AUF FESTEN TRÄGERN 有权
标题翻译：程序的生物聚合物在固体载体上局部特定合成
公开(公告)号：EP1814656B1
公开(公告)日：2011-01-05
申请号：EP05814266.2
申请日：2005-11-25
申请人： Clondiag GmbH
发明人： ELLINGER, Thomas , ERMANTRAUT, Eugen , HOLZHEY, Nancy , PLENZ, Frank , SCHULZ, Torsten , TUCHSCHEERER, Jens , WEICHERDING, Daniel
IPC分类号： B01J19/00 , C40B50/14 , C40B40/06
CPC分类号： B82Y30/00 , B01J19/0046 , B01J2219/0043 , B01J2219/00659 , B01J2219/00662 , B01J2219/00675 , B01J2219/00722 , B01J2219/00725 , C40B40/06 , C40B40/10 , C40B50/14 , C40B60/14
摘要： The invention relates to a method for specifically located synthesis of biopolymers such as nucleic acids or peptides and the respective derivatives thereof on solid carriers, wherein local discrimination of synthesis is carried out particularly with the aid of masks, directing aqueous activation reagents for the cleavage of protective groups to predetermined areas on the carrier.

9. 发明授权

EP2078189B1 ASSAY DEVICES AND METHODS FOR THE DETECTION OF ANALYTES 有权
标题翻译： TESTVORRICHTUNGEN UNDOVERHORRICHTUNG ZUM NACHWEIS VON ANALYTEN
公开(公告)号：EP2078189B1
公开(公告)日：2012-10-10
申请号：EP07821666.0
申请日：2007-10-22
申请人： Clondiag GmbH
发明人： ERMANTRAUT, Eugen , SCHULZ, Torsten , ELLINGER, Thomas , WEICHERDING, Daniel
IPC分类号： G01N21/64 , B01L3/00 , C12Q1/68
CPC分类号： B01L3/502707 , B01L2300/0636 , B01L2300/069 , B01L2300/0877 , B01L2400/0481 , C12Q1/6834
摘要： The present invention relates to devices and methods for performing assays, especially for determining the presence and/or amount of one or more analytes. In particular, the invention relates to a device for the detection of analytes, comprising a reversibly compressible matrix located between a first surface and a second surface, wherein the second surface is located opposite to the first surface, and wherein the distance between the first surface and the second surface is variable. The invention also relates to a corresponding method using such a device for the detection of one or more species of analytes.
摘要翻译：本发明涉及用于进行测定的装置和方法，特别是用于确定一种或多种分析物的存在和/或量。特别地，本发明涉及用于检测分析物的装置，包括位于第一表面和第二表面之间的可逆压缩基质，其中第二表面位于与第一表面相对的位置，并且其中第一表面并且第二表面是可变的。本发明还涉及使用这种装置检测一种或多种分析物的相应方法。

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