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1. 发明申请

WO2007071584A2 USE OF TRANSMISSION DYES 审中-公开
标题翻译：使用传染性染色体
公开(公告)号：WO2007071584A2
公开(公告)日：2007-06-28
申请号：PCT/EP2006/069519
申请日：2006-12-11
申请人： CIBA SPECIALTY CHEMICALS HOLDING INC. , MÜLLER, Stefan , HAASE, Jürg , EHLIS, Thomas , KREYER, Gilbert , GIESINGER, Jochen , VOGT, Martin
发明人： MÜLLER, Stefan , HAASE, Jürg , EHLIS, Thomas , KREYER, Gilbert , GIESINGER, Jochen , VOGT, Martin
CPC分类号： C07D295/192 , A61K8/411 , A61K8/42 , A61K8/49 , A61K8/494 , A61K2800/43 , A61Q17/04
摘要： Disclosed is the use of an aqueous dispersion comprising (a) a micronized sparingly soluble organic compound which has a UV-Vis spectrum with a maximum from 380 to 420 nm; and (b) an anionic dispersing agent for protecting the human skin from browning and skin aging.
摘要翻译：公开了包含（a）微波化的微溶有机化合物的水分散体的使用，其具有最大值为380至420nm的UV-Vis光谱; 和（b）用于保护人体皮肤免于褐变和皮肤老化的阴离子分散剂。

2. 发明申请

WO2006114381A1 USE OF BENZOTRIAZOLE DERIVATIVES FOR PHOTOSTABILISATION 审中-公开
标题翻译：苯并噻唑衍生物用于光化学的用途
公开(公告)号：WO2006114381A1
公开(公告)日：2006-11-02
申请号：PCT/EP2006/061686
申请日：2006-04-20
申请人： CIBA SPECIALTY CHEMICALS HOLDING INC. , MÜLLER, Stefan , GIESINGER, Jochen , EHLIS, Thomas , HERZOG, Bernd , KÖNIG, Peter , KREYER, Gilbert , QUASS, Katja
发明人： MÜLLER, Stefan , GIESINGER, Jochen , EHLIS, Thomas , HERZOG, Bernd , KÖNIG, Peter , KREYER, Gilbert , QUASS, Katja
IPC分类号： A61K8/49 , A61Q17/04
CPC分类号： A61Q17/04 , A61K8/496 , A61K2800/52
摘要： Use of benzotriazole derivatives of formula (1), wherein R 1 is C 1 -C 30 alkyl; C 1 C 5 alkoxy; C 1 -C 5 alkoxycarbonyl; C 5 -C 7 cycloalkyl; C 6 -C 10 aryl; aralkyl; -SO 3 M; a radical of formula (1a) R 3 is hydrogen; C 1 C 5 alkyl; C 1 C 5 alkoxy; halogen, preferably Cl; or hydroxy; R 4 and R 5 are each independently of the other hydrogen; or d-C 5 alkyl; m is 1 or 2; n is O or 1 ; if m = 1 , R 2 is hydrogen; unsubstituted or phenyl-substituted d-C 1 -C 12 alkyl; or C 6 -C 10 aryl; if m = 2, R2 is the direct bond; or -(CH 2 ) P -; and p is 1 to 3; for enhancing the photostability of cosmetic or dermatologic compositons comprising at least one further organic UV absorber.
摘要翻译：式（1）的苯并三唑衍生物的用途，其中R 1是C 1 -C 30烷基; ç_{1 C _{5 烷氧基; ç_{1 -C _{5 烷氧基羰基; ç_{5 -C _{7 环烷基; ç_{6 -C _{10 芳基; 芳; -SO _{3 米; 式（1a）R 3的基团是氢; ç_{1 C _{5 烷基; ç_{1 C _{5 烷氧基; 卤素，优选Cl; 或羟基; R 4和R 5各自独立地为氢; 或C 1 -C 5烷基; m为1或2; n为0或1; 如果m = 1，R 2是氢; 未取代或苯基取代的C 1 -C 12烷基; 或C 6 -C 10芳基; 如果m = 2，则R2是直接键; 或 - （CH 2）2 - 。 p为1〜3; 用于增强包含至少一种其它有机UV吸收剂的化妆品或皮肤病学组合物的光稳定性。}}}}}}}}}}}}}

3. 发明申请

WO2006008252A1 LIGHT PROTECTING-EFFECTIVE COSMETIC OR DERMATOLOGICAL PREPARATIONS 审中-公开
标题翻译：光保护有效的化妆品或皮肤制剂
公开(公告)号：WO2006008252A1
公开(公告)日：2006-01-26
申请号：PCT/EP2005/053301
申请日：2005-07-11
申请人： CIBA SPECIALTY CHEMICALS HOLDING INC. , MÜLLER, Stefan , EHLIS, Thomas , GIESINGER, Jochen , KREYER, Gilbert
发明人： MÜLLER, Stefan , EHLIS, Thomas , GIESINGER, Jochen , KREYER, Gilbert
IPC分类号： A61K7/42
CPC分类号： A61Q17/04 , A61K8/02 , A61K9/107 , A61K2800/412
摘要： Disclosed is the use of an insoluble or sparingly soluble micronized substance class which is not a cosmetic UV absorber and which is dispersed in the oil- or water-phase of a cosmetic or dermatological composition for the enhancement of light protecting action of this cosmetic or dermatological composition comprising at least one cosmetic UV filter which is soluble in the water- or oil-phase. The cosmetic preparation according to the invention shows a remarkable increase in SPF.
摘要翻译：公开了使用不是化妆品UV吸收剂并且分散在化妆品或皮肤病学组合物的油相或水相中的不溶性或微溶的微粉化物质类，以增强该化妆品或皮肤病学的光保护作用组合物，其包含至少一种可溶于水相或油相的化妆品UV过滤器。根据本发明的化妆品显示出SPF的显着增加。

4. 发明申请

WO2005058269A1 MEROCYANINE DERIVATIVES FOR COSMETIC USE 审中-公开
标题翻译：用于化妆品使用的MEROCANANINE衍生物
公开(公告)号：WO2005058269A1
公开(公告)日：2005-06-30
申请号：PCT/EP2004/053327
申请日：2004-12-08
申请人： CIBA SPECIALTY CHEMICALS HOLDING INC. , WAGNER, Barbara , EHLIS, Thomas , MÜLLER, Stefan
发明人： WAGNER, Barbara , EHLIS, Thomas , MÜLLER, Stefan
IPC分类号： A61K7/42
CPC分类号： C07D295/116 , A61K8/41 , A61K8/44 , A61K8/46 , A61K8/494 , A61K8/81 , A61Q17/00 , A61Q17/02 , C07C225/20 , C07C229/46 , C07C255/31 , C07C317/48 , C07C2601/14 , C07C2601/16 , C07D295/155
摘要： Described are merocyanine derivatives of formula (1a) or (1b) wherein n and o are integers from 2 to 4 and aminocyclohexenone intermediates. They are used in protecting human and animal hair and skin from UV radiation.
摘要翻译：描述的是式（1a）或（1b）的部花青衍生物，其中n和o是2-4的整数和氨基环己烯酮中间体。它们用于保护人体和动物的毛发和皮肤免受紫外线辐射。

5. 发明申请

WO2004085412A2 SYMMETRICAL TRIAZINE DERIVATIVES 审中-公开
标题翻译：对称TRIAZINE衍生物
公开(公告)号：WO2004085412A2
公开(公告)日：2004-10-07
申请号：PCT/EP2004/050331
申请日：2004-03-19
申请人： CIBA SPECIALTY CHEMICALS HOLDING INC. , EHLIS, Thomas , MÜLLER, Stefan , HAYOZ, Pascal
发明人： EHLIS, Thomas , MÜLLER, Stefan , HAYOZ, Pascal
IPC分类号： C07D251/24
CPC分类号： C07D251/24 , A61K8/4966 , A61Q17/04
摘要： Disclosed is the use of the compounds of formula wherein A is a radical of formula (1a) or (1b) R, R 1 and R 5 independently from each other are hydrogen; C 1 -C 18 alkyl; or C 6 -C 12 aryl; R 2 , R 3 and R 4 independently from each other are hydrogen; or a radical of formula wherein at least one of the radicals R 2 , R 3 and R 4 are a radical of formula (1c); R 6 , R 7 , R 8 , R 9 and R 10 independently from each other are hydrogen; hydroxy; C 1 -C 18 alkyl; C 1 -C 18 alkoxy;C 6 -C 12 aryl; C 6 -C 12 aryloxy; C 1 -C 18 alkylthio; carboxy; -COOM; C 1 -C 18 alkylcarboxyl; aminocarbonyl; or mono- or di-C 1 -C 18 alkylamino; M is an alkali metal ion; x is 1 or 2; and y is a number from 2 to 10; for the protection of human and animal hair and skin against the damaging effect of UV radiation. The compounds of formula (1) are high effective UV absorbers for cosmetic formulations aund can - depending on their physical properties - be used in micronized or soluble form.
摘要翻译：公开了下式化合物的用途其中A是式（1a）或（1b）的基团，R，R 1和R 5彼此独立地是氢; C1-C18烷基; 或C6-C12芳基; R2，R3和R4彼此独立地是氢; 或下式的基团，其中基团R 2，R 3和R 4中的至少一个为式（1c）的基团; R 6，R 7，R 8，R 9和R 10彼此独立地为氢; 羟基; C1-C18烷基; C1-C18烷氧基; C 6 -C 12芳基; C6-C12aryloxy; C1-C18alkylthio; 羧基; -COOM; C1-C18alkylcarboxyl; 羰基; 或单或二C1-C18烷基氨基; M是碱金属离子; x为1或2; y为2〜10的数; 用于保护人体和动物毛发和皮肤免受紫外线辐射的破坏作用。式（1）的化合物是用于化妆品制剂的高效紫外线吸收剂，可根据其物理性质 - 以微粉化或可溶形式使用。

6. 发明申请

WO2007090832A1 HYDROXYBENZOPHENONE DERIVATIVES 审中-公开
标题翻译：羟基苯并噻吩衍生物
公开(公告)号：WO2007090832A1
公开(公告)日：2007-08-16
申请号：PCT/EP2007/051117
申请日：2007-02-06
申请人： CIBA SPECIALTY CHEMICALS HOLDING INC. , HAASE, Jürg , MÜLLER, Stefan , EHLIS, Thomas
发明人： HAASE, Jürg , MÜLLER, Stefan , EHLIS, Thomas
IPC分类号： C07F7/08 , A61Q17/04 , A61K8/58
CPC分类号： C07F7/0854 , A61K8/585 , A61Q17/04
摘要： Disclosed are hydroxyphenylbenzophenone derivatives of formula (1), wherein R 1 and R 2 independently from each other are hydrogen; C 1 -C 20 alkenyl; C 3 - C 10 cycloalkyl; or R 1 and R 2 together with the linking nitrogen atom form a 5- 6-membered heterocyclic ring; R 3 , R 4 and R 5 independently from each other are C 1 -C 4 alkyl; C 1 -C 4 alkoxy; or a radical of formula (1a) R 6 is C 1 -C 6 alkyl; and A is a straight-chain or branched C 3 -C 6 alkylene, which is optionally interrupted by one or more *-O-*, or *-O-(CO)-* groups; and m is 0; or anumber from 1 to 5. The compounds are useful as cosmetic UV filters with outstanding solubility properties in cosmetic oils.
摘要翻译：公开了式（1）的羟基苯基二苯甲酮衍生物，其中R 1和R 2彼此独立地是氢; ç_{1 -C _{20 烯基; C 3 -C 10环烷基; 或R 1和R 2与连接氮原子一起形成5-6元杂环; R 3，R 4和R 5彼此独立地是C 1 -C 4烷基， / SUB>烷基; ç_{1 -C _{4 烷氧基; 或式（1a）的基团R 6是C 1 -C 6烷基; 并且A是直链或支链C 3 -C 6亚烷基，其任选地被一个或多个* -O- *或* -O-（ CO） - *组; m为0; 或1至5的编号。该化合物可用作化妆品油中具有优异溶解性的化妆品UV过滤器。}}}}

7. 发明申请

WO2004052837A2 AMINO SUBSTITUTED HYDROXYPHENYL BENZOPHENONE DERIVATIVES 审中-公开
标题翻译：氨基取代的羟基苯并噻吩酮衍生物
公开(公告)号：WO2004052837A2
公开(公告)日：2004-06-24
申请号：PCT/EP2003/050937
申请日：2003-12-03
申请人： CIBA SPECIALTY CHEMICALS HOLDING INC. , HAASE, Jürg , EHLIS, Thomas , BORSOS, Elek , MÜLLER, Stefan
发明人： HAASE, Jürg , EHLIS, Thomas , BORSOS, Elek , MÜLLER, Stefan
IPC分类号： C07C229/52
CPC分类号： C07D295/192 , A61K8/42 , A61K8/44 , A61K8/49 , A61K8/4973 , A61Q17/04 , C07C229/52 , C07C237/32 , C07C237/34 , C07C237/40 , C07C237/42 , C07D277/46 , C07D277/66 , C07D313/12
摘要： Described are amino substituted hydroxyphenyl benzophenone derivatives of formula (I), wherein R 1 , and R 2 independently from each other are; C 1 ,-C 20 alkyl; C 2 -C 20 alkenyl; C 3 -C 10 ,cycloalkyl; C 3 -C 10 cycloalkenyl; or R 1 , and R 2 together with the linking nitogen atom form a 5- or 6-membered heterocyclic ring; n 1 is a number from 1 to 4; when n 1 =1, R 3 is a saturated or unsaturated heterocyclic radical; hydroxy-C 1 -C 5 alkyl; cyclohexyl optionally substituted with one or more C 1 ,-C 5 alkyl; phenyl optionally substituted with a heterocyclic radical, aminocarbonyl or C 1 -C 5 alkylcarboxy; wenn n 1 is 2, R 3 is an alkylene-, cycloalkylene- or alkenylene radical which is optionally substituted by a carbonyl- or carboxy group; o R 3 together with A forms a bivalent radical of the formula (Ia), wherein n 2 is a number from 1 to 3; when n 1 is 3, R 3 is an alkanetriyl radical; wenn n 1 is 4, R 3 is an alkanetetrayl radical; A is -O-; or -N(R 5 )-; and R 5 is hydrogen; C 1 -C 5 alkyl; or hydroxy-C 1 -C 5 alkyl. The compounds are useful as UV filters in sunscreen applications.
摘要翻译：描述了式（I）的氨基取代的羟基苯基二苯甲酮衍生物，其中R1和R2彼此独立地是; C1，-C20alkyl; C2-C20alkenyl; C3-C10，环烷基; C3-C10cycloalkenyl; 或R1和R2与连接的硝原子一起形成5-或6-元杂环; n1是从1到4的数字; 当n1 = 1时，R3是饱和或不饱和杂环基; 羟基C1-C5烷基; 任选被一个或多个C 1 -C 5烷基取代的环己基; 任选被杂环基取代的苯基，氨基羰基或C 1 -C 5烷基羧基; wn1是2，R3是任选被羰基或羧基取代的亚烷基，亚环烷基或亚烯基; O与A一起形成式（Ia）的二价基团，其中n2为1至3的数; 当n1为3时，R3为烷三基; wenn n1为4，R3为烷基四氢呋喃基; A为-O- 或-N（R 5） - ; R5是氢; C1-C5烷基; 或羟基-C 1 -C 5烷基。这些化合物可用作防晒霜中的紫外线过滤器。

8. 发明申请

WO2007128744A3 TRIAZINE DERIVATIVES 审中-公开
公开(公告)号：WO2007128744A3
公开(公告)日：2007-11-15
申请号：PCT/EP2007/054239
申请日：2007-05-02
申请人： CIBA SPECIALTY CHEMICALS HOLDING INC. , EHLIS, Thomas , BORSOS, Elek
发明人： EHLIS, Thomas , BORSOS, Elek
IPC分类号： C07D251/52 , C07D251/70 , A61Q17/04
摘要： Disclosed are triazine derivatives of formula (1), wherein X 1 is a bivalent radical of formula (1a) -NR 9 -A-NR 9 -; (1b); or (1c) *-O-A-O-* A and A' independently from each other are unsubstituted or substituted, straight-chain or branched C 1 -C 12 alkylene, which is optionally interrupted by C 5 -C 12 cycloalkylene, N, O or S; C 5 -C 12 cycloalkylene; biphenylene; C 6 -C 10 arylene; or C 5 -C 10 arylene-(C 1 -C 12 alkylene); R 1 is a radical of formula (1d); (1e); (1f); (1g); or (1h); R 2 and R 3 independently from each other are hydrogen; C 1 -C 12 alkyl; OR 7 ; NR 7 R 8 ; C 6 -C 10 aryl; X 2 is O, or NH; W 1 is C 1 -C 20 alkyl; or a group Sp-Sil; Sp is a straight-chain or branched saturated or single or multiple unsaturated C 3 -C 12 hydrocarbon; Sil is a silane; an oligosiloxane; or a polysiloxane moiety; and R 4 , R 5 R 6 , R 7 , R 8 and R 9 independently from each other are hydrogen; C 1 -C 12 alkyl; or C 3 -C 12 cycloalkyl.

9. 发明申请

WO2007093513A1 AROMATIC SULPHONATE FLAME RETARDANT COMPOSITIONS 审中-公开
标题翻译：芳香磺化阻燃剂组合物
公开(公告)号：WO2007093513A1
公开(公告)日：2007-08-23
申请号：PCT/EP2007/051058
申请日：2007-02-05
申请人： CIBA SPECIALTY CHEMICALS HOLDING INC. , BREINER, Christine , EHLIS, Thomas , HOCHBERG, Robert , KNIESEL, Simon
发明人： BREINER, Christine , EHLIS, Thomas , HOCHBERG, Robert , KNIESEL, Simon
IPC分类号： C08K5/42 , C08K5/00 , C08L69/00 , C08K5/3475 , C08K5/13 , C08K5/353
CPC分类号： C08K5/45 , C08K5/42 , C08L69/00 , C08L2666/18
摘要： The invention relates to flame retardant compositions, wherein salts of selected aromatic sulphonic acids are present in a polycarbonate substrate. The compositions attain the desirable V-0 rating, according to UL-94 (Underwriter's Laboratories Subject 94) and other excellent ratings in related test methods while preserving the excellent mechanical, chemical and thermal properties of polycarbonates, such as light transparency.
摘要翻译：本发明涉及阻燃组合物，其中选择的芳族磺酸的盐存在于聚碳酸酯底物中。根据UL-94（Underwriter's Laboratories Subject 94）和相关测试方法中的其它优异等级，组合物达到所需的V-0等级，同时保持聚碳酸酯的优异的机械，化学和热性能，例如光透明度。

10. 发明申请

WO2004006878A1 MEROCYANINE DERIVATIVES FOR COSMETIC USE 审中-公开
标题翻译：用于化妆品使用的MEROCANANINE衍生物
公开(公告)号：WO2004006878A1
公开(公告)日：2004-01-22
申请号：PCT/EP2003/006955
申请日：2003-07-01
申请人： CIBA SPECIALTY CHEMICALS HOLDING INC. , WAGNER, Barbara , EHLIS, Thomas , EICHIN, Kai
发明人： WAGNER, Barbara , EHLIS, Thomas , EICHIN, Kai
IPC分类号： A61K7/42
CPC分类号： C07D239/54 , A61K8/4906 , A61Q17/04 , C07C255/30 , C07C255/31 , C07C2601/16 , C07D207/20 , C07D231/36 , C07D263/14 , C07D277/10 , C07D295/145 , C07D295/155 , C07D319/06
摘要： The use is described of merocyanine derivatives of formula (1), wherein R 1 and R 2 are each independently of the other hydrogen; C 1 -C 22 alkyl; cyclo-C 3 C 8 alkyl; or unsubstituted or C 1 -C 5 alkyl- or C 1 -C 5 alkoxy-substituted C 6 -C 20 aryl; orl; or R 1 and R 2 together with the nitrogen atom linking them form a -(CH 2 ) m - ring which is uninterrupted or. interrupted by -O- or by -NH-; R 3 is a cyano group; -COOR 5 ; -CONHR 5 ; -COR 5 ; or -SO 2 R 5 ; R 4 is a cyano group; -COOR 6 ; -CONHR 6 ; -COR 6 ; or -SO 2 R 6 ; R 5 and R 6 are each independently of the other C 1 -C 22 alkyl; or unsubstituted or C 1 -C 5 alkyl substituted C 6 -C 20 aryl; or R 3 and R 4 together or R 5 and R 6 together form a 5- to 7-membered, monocyclic, carbocyclic or heterocyclic ring; Z 1 , and Z 2 are each independently of the other a -(CH 2 ),- group which is uninterrupted or interrupted by -O-, -S-, or by -NR 7 -, and/or is unsubstituted or substituted by C, 1 -C 5 alkyl; R 7 is C 1 C 5 alkyl; I is from 1 to 4; m is from 1 to 7; n is from 1 to 4; when n = 2, R 1 , R 5 or R 6 is a bivalent alkyl group; or R 1 , and R 2 together with the 2 nitrogen atoms linking them form a -(CH 2 ) m - ring; when n = 3, R 1 , R 5 or R 6 is a trivalent alkyl group; when n = 4, R 1 , R 5 or R 6 is a tetravalent alkyl group; and R 1 , and R 2 in formula (1) are not simultaneously hydrogen, in protecting human and animal hair and skin from UV radiation.
摘要翻译：描述了式（1）的部花青衍生物，其中R 1和R 2各自独立地为氢; C1-C22烷基; 环C3C8alkyl; 或未取代的或C 1 -C 5烷基 - 或C 1 -C 5烷氧基取代的C 6 -C 20芳基; ORL; 或R 1和R 2与连接它们的氮原子一起形成不间断的 - （CH 2）m - 环。被-O-或-NH-中断; R3是氰基; -COOR5; -CONHR5; -COR5; 或-SO 2 R 5; R4是氰基; -COOR6; -CONHR6; -COR 6; 或-SO 2 R 6; R 5和R 6各自独立地为C 1 -C 22烷基; 或未取代的或C 1 -C 5烷基取代的C 6 -C 20芳基; 或R 3和R 4一起或R 5和R 6一起形成5-至7-元单环，碳环或杂环; Z 1和Z 2各自独立地为不间断或被-O - ， - S-或-NR 7 - 间隔的另一个 - （CH 2） - 基，和/或未取代或被C 1〜 C 5烷基; R7是C1C5烷基; 我是从1到4; m为1〜7; n为1至4; 当n = 2时，R 1，R 5或R 6为二价烷基; 或R 1和R 2与连接它们的2个氮原子一起形成 - （CH 2）m - 环; 当n = 3时，R 1，R 5或R 6为三价烷基; 当n = 4时，R 1，R 5或R 6为四价烷基; 式（1）中的R 1和R 2不同时为氢，以保护人和动物的头发和皮肤免受UV辐射。

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