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1. 发明申请

WO2006002236A1 N- (1- (1-BENZYL -4-PHENYL-1H-IMIDAZOL-2-YL) -2,2-DYMETHYLPROPYL) BENZAMIDE DERIVATIVES AND RELATED COMPOUNDS AS KINESIN SPINDLE PROTEIN (KSP) INHIBITORS FOR THE TREATMENT OF CANCER 审中-公开
标题翻译： N-（1-（1-苄基-4-苯基-1H-咪唑-2-基）-2,2-二甲基丙基）苯甲酰胺衍生物及相关化合物作为治疗癌症的KINESIN主轴蛋白（KSP）抑制剂
公开(公告)号：WO2006002236A1
公开(公告)日：2006-01-05
申请号：PCT/US2005/022062
申请日：2005-06-20
申请人： CHIRON CORPORATION , WANG, Weibo , BARSANTI, Paul, A. , XI, Yi , BOYCE, Rustum, S. , PECCHI, Sabina , BRAMMEIER, Nathan , PHILLIPS, Megan , MENDENHALL, Kris , WAYMAN, Kelly , LAGNITON, Liana, Marie , CONSTANTINE, Ryan , YANG, Hong , MIEULI, Elizabeth , RAMURTHY, Savithri , JAZAN, Elisa , SHARMA, Anu , RAMA, Jain , SABRAMANIAN, Sharadha , RENHOWE, Paul , BAIR, Kenneth, Walter , DUHL, David , WALTER, Annette , ABRAMS, Tinya , HUH, Kay , MARTIN, Eric , KNAPP, Mark , LE, Vincent
发明人： WANG, Weibo , BARSANTI, Paul, A. , XI, Yi , BOYCE, Rustum, S. , PECCHI, Sabina , BRAMMEIER, Nathan , PHILLIPS, Megan , MENDENHALL, Kris , WAYMAN, Kelly , LAGNITON, Liana, Marie , CONSTANTINE, Ryan , YANG, Hong , MIEULI, Elizabeth , RAMURTHY, Savithri , JAZAN, Elisa , SHARMA, Anu , RAMA, Jain , SABRAMANIAN, Sharadha , RENHOWE, Paul , BAIR, Kenneth, Walter , DUHL, David , WALTER, Annette , ABRAMS, Tinya , HUH, Kay , MARTIN, Eric , KNAPP, Mark , LE, Vincent
IPC分类号： C07D233/54
CPC分类号： C07D233/54 , C07D233/24 , C07D233/64 , C07D401/04 , C07D401/06 , C07D401/12 , C07D403/04 , C07D403/12 , C07D403/14 , C07D405/06 , C07D405/12 , C07D413/06 , C07D413/12 , C07D413/14 , C07D417/04 , C07D417/06 , C07D417/12 , C07D417/14 , C07D498/10
摘要： This invention is directed to substituted imidazole compounds which modulate the activity of KSP and are useful for the treatment of cancer and are represented by the formula (I) wherein: R 1 is selected from the group consisting of aminoacyl, acylamino, carboxyl, carboxyl ester, aryl, and alkyl optionally substituted with hydroxy or halo; R 2 is selected from the group consisting of hydrogen, alkyl, and aryl; R 3 is selected from the group consisting of hydrogen and -X-A, wherein X is selected from the group consisting of-C(O)-, -C(S)-, -S(O)-, -S(O) 2 -, and -S(O)2-N(R)-, where R is hydrogen or alkyl; and A is selected from the group consisting of hydrogen, optionally substituted alkyl, optionally substituted alkoxy, optionally substituted aryl, carboxyl, carboxyl ester, aminoacyl, optionally substituted heteroaryl, optionally substituted heterocyclic, and optionally substituted cycloalkyl, wherein the optionally substituted groups are substituted with 1 to 4 substituents; R 5 is selected from the group consisting of L-A 1 , wherein L is selected from the group consisting of-S(O) q - where q is one or two, and C 1 to C 5 alkylene optionally substituted with hydroxy, halo, or acylamino; and A 1 is selected from the group consisting of aryl, substituted aryl, heteroaryl, substituted heteroaryl, heterocyclic, substituted heterocyclic, cycloalkyl, and substituted cycloalkyl; and one of either R 6 or R 7 is selected from the group consisting of heterocyclic, aryl and heteroaryl, all of which may be optionally substituted with -(R 8 ) m where R 8 is as defined herein and m is an integer from 1 to 3, and the other Of R 6 or R 7 is selected from the group consisting of hydrogen, halo, and alkyl; or R 6 and R 7 are both hydrogen; the other substituents are defined in the claims.
摘要翻译：本发明涉及调节KSP活性并且可用于治疗癌症并由式（I）表示的取代的咪唑化合物，其中：R 1选自氨基酰基酰基氨基，羧基，羧基酯，芳基和任选被羟基或卤素取代的烷基; R 2选自氢，烷基和芳基; R 3选自氢和-XA，其中X选自-C（O） - ， - C（S） - ， - S（O） - ，-S（O）2 - 和-S（O）2 -N（R） - ，其中R是氢或烷基; 并且A选自氢，任选取代的烷基，任选取代的烷氧基，任选取代的芳基，羧基，羧基酯，氨酰基，任选取代的杂芳基，任选取代的杂环和任选取代的环烷基，其中任选取代的基团被取代具有1至4个取代基; R 5选自LA 1，其中L选自-S（O）q - ，其中 q是一个或两个，并且C 1至C 5亚烷基，其任选被羟基，卤素或酰基氨基取代; 并且A 1选自芳基，取代的芳基，杂芳基，取代的杂芳基，杂环，取代的杂环，环烷基和取代的环烷基; 且R 6或R 7中的一个选自杂环，芳基和杂芳基，其全部可以任选地被 - （R' 其中R 8如本文所定义，m是1至3的整数，R 6中的另一个或R 7选自氢，卤素和烷基; 或R 6和R 7都是氢; 其它取代基在权利要求中限定。

2. 发明申请

WO2008086122A2 CYCLIZED DERIVATIVES AS EG-5 INHIBITORS 审中-公开
标题翻译：循环衍生物作为EG-5抑制剂
公开(公告)号：WO2008086122A2
公开(公告)日：2008-07-17
申请号：PCT/US2008/050149
申请日：2008-01-03
申请人： NOVARTIS AG , BOYCE, Rustum , MARTIN, Eric , WANG, Weibo , YANG, Hong , BARSANTI, Paul A.
发明人： BOYCE, Rustum , MARTIN, Eric , WANG, Weibo , YANG, Hong , BARSANTI, Paul A.
IPC分类号： C07D413/06 , C07D403/06 , A61K31/422 , A61P35/00
CPC分类号： C07D403/06 , C07D413/06
摘要： The present invention relates to new substituted imidazole compounds have the following Formula (I) and to the pharmaceutically acceptable salts, esters, or prodrugs thereof, to compositions of the compounds together with pharmaceutically acceptable carriers, and to uses of the compounds: (I).
摘要翻译：本发明涉及具有下式（I）的新的取代咪唑化合物及其药学上可接受的盐，酯或前药与化合物与药学上可接受的载体的组合物，以及该化合物的用途：（I）。

3. 发明申请

WO2018175345A1 GARMENT BUTTON WITH SLIDABLE TRACK FOR TIGHTENING AND LOOSENING OF A GARMENT 审中-公开
公开(公告)号：WO2018175345A1
公开(公告)日：2018-09-27
申请号：PCT/US2018/023181
申请日：2018-03-19
申请人： MARTIN, Eric
发明人： MARTIN, Eric
IPC分类号： A41D1/06 , A41D15/00 , A41F9/02
摘要： This invention relates to devices that adjust the fit of a garment. Previously, a fastener that allowed for customization or adjustment of sizes was needed. Embodiments of the present invention use a track (38) having a plurality of track teeth. A button has a shoe designed to removably engage with the track. A spring is operatively engaged with the shoe. A plurality of button teeth is operatively attached to the spring. When the spring is not compressed, the plurality of button teeth is designed to removably engage with the plurality of track teeth. When the spring is compressed, the plurality of button teeth is designed to disengage from the plurality of track teeth.

4. 发明申请

WO2012044299A1 THERMAL SENSING FLUID EJECTION ASSEMBLY AND METHOD 审中-公开
标题翻译：传感流体组件和方法
公开(公告)号：WO2012044299A1
公开(公告)日：2012-04-05
申请号：PCT/US2010/050853
申请日：2010-09-30
申请人： HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. , BROWNING, Robert N.K. , GARDNER, James , MARTIN, Eric , VAN BROCKLIN, Andrew L. , HUNTER, Mark
发明人： BROWNING, Robert N.K. , GARDNER, James , MARTIN, Eric , VAN BROCKLIN, Andrew L. , HUNTER, Mark
IPC分类号： B41J2/14 , B41J2/32
CPC分类号： B41J2/135 , B41J2/1408 , B41J2/14145
摘要： A fluid ejection assembly includes a fluid slot formed in a die. The assembly also includes a nozzle column is formed along a side of the fluid slot. The assembly also includes a pair of thermal sensors to measure die temperature at the middle of the nozzle column and at a first end of the nozzle column.
摘要翻译：流体喷射组件包括形成在模具中的流体槽。组件还包括沿着流体槽的一侧形成的喷嘴柱。该组件还包括一对热传感器，用于测量喷嘴列中间和喷嘴列的第一端处的模具温度。

5. 发明申请

WO2011095727A1 PROCEDE DE DEPÔT D'UN LIQUIDE SUR LE BUVANT D'UN RECIPIENT 审中-公开
标题翻译：将液体沉积在集装箱的锁定环上的方法
公开(公告)号：WO2011095727A1
公开(公告)日：2011-08-11
申请号：PCT/FR2011/050149
申请日：2011-01-26
申请人： SAINT-GOBAIN EMBALLAGE , CHAUVET, Boris , MERTZ, Frédéric , MARTIN, Eric
发明人： CHAUVET, Boris , MERTZ, Frédéric , MARTIN, Eric
IPC分类号： B05C17/02
CPC分类号： B05C17/0207
摘要： L'invention a pour objet : un procédé de dépôt d'un liquide sur le buvant d'un récipient par transfert à partir d'un rouleau dont la surface est constituée d'un tricot tubulaire à mailles cueillies ou jetées de contexture côte 2 x 1; un pot ou récipient équivalent en verre, dont le buvant comporte un revêtement de vernis, promoteur d'adhésion ou primaire de thermoscellage formé par un procédé de dépôt; un pot ou récipient équivalent comportant un opercule thermoscellé au buvant.
摘要翻译：本发明涉及一种通过从辊转移而将液体沉积到容器的锁定环上的方法，辊的表面由具有2×1肋纹理的纬针或经编针迹的管状针织物组成，一种罐或类似的玻璃容器，其锁定环包括通过沉积方法形成的釉料涂层，粘合促进剂或热封底漆，以及包括密封件的罐或类似的玻璃容器，所述密封件被热密封到锁环。

6. 发明申请

WO2010050977A1 THERMAL FLUID-EJECTION DEVICE DIE 审中-公开
标题翻译：热流体喷射装置
公开(公告)号：WO2010050977A1
公开(公告)日：2010-05-06
申请号：PCT/US2008/082112
申请日：2008-10-31
申请人： HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. , VAN BROCKLIN, Andrew L. , BAKKER, Chris , HUNTER, Mark , MARTIN, Eric
发明人： VAN BROCKLIN, Andrew L. , BAKKER, Chris , HUNTER, Mark , MARTIN, Eric
IPC分类号： B41J2/05 , B41J2/01
CPC分类号： B41J2/0458 , B41J2/04541 , B41J2/04548 , B41J2/0455
摘要： A die for a thermal drop-on-demand fluid-ejection device includes thermal firing resistors, low-side switches, and high-side switches. The thermal firing resistors are organized over resistor groups such that each thermal firing resistor is located within only one of the resistor groups. The resistor groups are lesser in number than the thermal firing resistors. Each thermal firing resistor has a first end and a second end. The low-side switches are equal in number to the thermal firing resistors. Each low-side switch connects the second end of a corresponding thermal firing resistor to a low voltage. The high-side switches are equal in number to the resistor groups. Each high-side switch connects the first ends of the thermal firing resistors of a corresponding resistor group to power providing a voltage greater than the low voltage.
摘要翻译：用于热滴式流体喷射装置的模具包括热激发电阻器，低侧开关和高侧开关。热触发电阻器组织在电阻器组上，使得每个热激发电阻器仅位于电阻器组之中。电阻组的数量比热激发电阻小。每个热激电阻器具有第一端和第二端。低边开关的数量与热激发电阻的数量相等。每个低侧开关将相应的热激发电阻器的第二端连接到低电压。高边开关的数量与电阻组数量相等。每个高侧开关将相应电阻器组的热激发电阻器的第一端连接到提供大于低电压的电压的功率。

7. 发明申请

WO2009143896A1 METHOD AND DEVICE FOR MANUFACTURING A PANEL OF LAMINATED GLASS 审中-公开
标题翻译：用于制造层压玻璃板的方法和装置
公开(公告)号：WO2009143896A1
公开(公告)日：2009-12-03
申请号：PCT/EP2008/056678
申请日：2008-05-30
申请人： AGC FLAT GLASS EUROPE SA , LUIJCKX, Antoine , LEFEVRE, Hugues , MARTIN, Eric
发明人： LUIJCKX, Antoine , LEFEVRE, Hugues , MARTIN, Eric
IPC分类号： B32B17/10 , C03C27/12
CPC分类号： B32B17/10954 , B32B17/10036 , B32B17/10174 , B32B17/10761 , B32B17/10981 , F21V33/006 , F21Y2115/10
摘要： The inventions relates to a method for manufacturing a panel of laminated glass 10 with the steps providing a first glass plate 1, providing a plastics interlayer 4, cutting the plastics interlayer 4 to a tailored sheet with dimensions which relate to the dimensions of the first glass plate 1, applying the tailored sheet of plastics interlayer 4 on the first glass plate 1, applying a second glass plate on the tailored sheet of plastics interlayer 4 and laminating the first glass plate 1, the tailored sheet of plastics interlayer 4 and the second glass plate. This is advantageous since the invention diminishes the cycle time of manufacturing a panel of laminated glass 10 and increases the yield.
摘要翻译：本发明涉及一种用于制造夹层玻璃板10的方法，其中步骤提供第一玻璃板1，提供塑料中间层4，将塑料中间层4切割成具有与第一玻璃的尺寸有关的尺寸的定制片板1，将定制的塑料中间层4应用在第一玻璃板1上，在定制的塑料中间层4上施加第二玻璃板，并将第一玻璃板1，定制的塑料中间层4和第二玻璃板盘子。这是有利的，因为本发明减少了制造夹层玻璃板10的循环时间并提高了产率。

8. 发明申请

WO2009129864A1 METHOD FOR DETECTING ELECTRICAL INHOMOGENEITIES CAUSED BY LOCAL DEFECTS IN A CONDUCTIVE LAYER AND CORRESPONDING APPARATUS 审中-公开
标题翻译：用于检测导电层和相应装置中局部缺陷引起的电气不均匀的方法
公开(公告)号：WO2009129864A1
公开(公告)日：2009-10-29
申请号：PCT/EP2008/055110
申请日：2008-04-25
申请人： AGC FLAT GLASS EUROPE SA , LUIJKX, Antoine , LEFEVRE, Hugues , MARTIN, Eric
发明人： LUIJKX, Antoine , LEFEVRE, Hugues , MARTIN, Eric
IPC分类号： G01R31/309 , G01R31/28
CPC分类号： G01R31/309 , G01R31/281
摘要： The invention relates to a method for detecting electrical inhomogeneities in a conductive layer 10 on a substrate 1 comprising the steps of heating the substrate between at least two connectors 11, 12 by applying a predetermined voltage level between the connectors 11, 12 in a predetermined direction on the substrate 1; and detecting local defects in the conductive layer 10 by determining changes in the coating temperature of the conductive layer 10 on the substrate 1. This way, a possibility for detecting electrical inhomogeneities in a conductive layer on a substrate is provided which is easy, fast and reliable.
摘要翻译：本发明涉及一种用于检测基片1上的导电层10中的电不均匀性的方法，包括以下步骤：通过在连接器11,12之间沿预定方向施加预定电压电平来在至少两个连接器11,12之间加热衬底在基板1上; 并且通过确定基板1上的导电层10的涂覆温度的变化来检测导电层10中的局部缺陷。这样，提供了检测基板上的导电层中的电不均匀性的可能性，其容易，快速和可靠。

9. 发明申请

WO2009100769A1 PICK-AND-PLACE METHOD AND CORRESPONDING PICK-AND-PLACE APPARATUS FOR MOUNTING COMPONENTS ON A SUBSTRATE 审中-公开
标题翻译：拾取和放置方法以及用于安装在基板上的组件的拾光和放置装置
公开(公告)号：WO2009100769A1
公开(公告)日：2009-08-20
申请号：PCT/EP2008/052728
申请日：2008-03-06
申请人： AGC FLAT GLASS EUROPE SA , LEFEVRE, Hugues , MARTIN, Eric
发明人： LEFEVRE, Hugues , MARTIN, Eric
IPC分类号： H05K13/04
CPC分类号： H05K13/0404
摘要： The present invention relates to a pick-and-place method and a corresponding pick-and-place apparatus for mounting electronic components, for example surface mounted device (SMD) components, on a substrate, in particular on a large-surface/large-area substrate. According to the invention, the pick-and-place apparatus comprises a material transport and support device (2), an x-y-positioning device (4) with one or several mounted electronic component mounting heads (5), wherein in at least one electronic component mounting head (5) comprises a visual system (8) for identifying form and/or position parameters of the head, substrate and/or component/s, a head rotation or translation system (10), one or several electronic component feeders (12), an electronic component mounting device (16). The apparatus also preferably has an electronic component testing device (18) for directly testing the component after mounting, and a control interface (20) for adjusting the parameters of the apparatus, in particular the form and/or position parameters of the head, substrate and/or component/s.
摘要翻译：本发明涉及一种拾取和放置方法和相应的拾取和放置装置，用于将电子部件（例如表面安装器件（SMD）部件）安装在基板上，特别是在大表面/ 区域底物。根据本发明，拾取和放置装置包括材料输送和支撑装置（2），具有一个或几个安装的电子部件安装头（5）的xy定位装置（4），其中在至少一个电子部件安装头（5）包括用于识别头部，基底和/或部件的形式和/或位置参数的视觉系统（8），头部旋转或平移系统（10），一个或多个电子部件馈送器 12），电子部件安装装置（16）。该装置还优选地具有用于在安装之后直接测试部件的电子部件测试装置（18）和用于调节装置的参数的控制接口（20），特别是头部，基板的形式和/或位置参数和/或组件。

10. 发明申请

WO2007098143A2 METHOD AND APPARATUS FOR SECURE OBJECT LABELING 审中-公开
标题翻译：用于安全对象标记的方法和设备
公开(公告)号：WO2007098143A2
公开(公告)日：2007-08-30
申请号：PCT/US2007/004342
申请日：2007-02-20
申请人： HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. , ANDERSON, Daryl E , MARTIN, Eric , VAN BROCKLIN, Andy , KOLL, Andrew
发明人： ANDERSON, Daryl E , MARTIN, Eric , VAN BROCKLIN, Andy , KOLL, Andrew
CPC分类号： G09F3/0292 , Y10T428/22 , Y10T428/24479 , Y10T428/24612
摘要： This invention relates to a label having improved security, comprising: a label substrate having a recessed portion; a layer of an energy activated material substantially located along a section of the recessed portion; and an optically transparent cover located substantially over the energy activated material such that the cover is substantially located within the recess.
摘要翻译：本发明涉及一种具有改进的安全性的标签，包括：具有凹陷部分的标签基底; 基本上沿凹陷部分的一部分设置的一层能量活化材料; 以及基本位于能量活化材料上方的光学透明盖，使得盖基本上位于凹槽内。

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