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1. 发明申请

WO2007022511A3 LISTERIA-INDUCED IMMUNORECRUITMENT AND ACTIVATION, AND METHODS OF USE THEREOF 审中-公开
标题翻译：李斯特菌诱导的免疫分泌和激活及其使用方法
公开(公告)号：WO2007022511A3
公开(公告)日：2007-09-13
申请号：PCT/US2006032648
申请日：2006-08-21
申请人： CERUS CORP , UNIV JOHNS HOPKINS , PARDOLL DREW M , SCHULICK RICHARD D , BAHJAT KEITH S , BROCKSTEDT DIRK G , DUBENSKY THOMAS W JR , GIEDLIN MARTIN A , JAIN AJAY , YOSHIMURA KIYOSHI
发明人： PARDOLL DREW M , SCHULICK RICHARD D , BAHJAT KEITH S , BROCKSTEDT DIRK G , DUBENSKY THOMAS W JR , GIEDLIN MARTIN A , JAIN AJAY , YOSHIMURA KIYOSHI
IPC分类号： A61K35/74 , A61P31/00 , A61P35/00 , A61P37/02
CPC分类号： A61K39/0011 , A61K31/675 , A61K35/13 , A61K35/74 , A61K38/193 , A61K2039/505 , A61K2039/522 , A61K2039/55522 , A61K2039/55544 , C07K16/2812 , C07K16/2815 , C12N1/36 , A61K2300/00 , A61K38/00
摘要： Provided are reagents and methods for administering an attenuated bacterium for use in treating a cancerous or infectious condition. Reagents and methods for administering an attenuated bacterium for use in inducing an immune response against a tumor, cancer cell, or infective agent are further provided. Also provided are methods of diagnosis and kits.
摘要翻译：提供了用于施用用于治疗癌症或感染症状的减毒细菌的试剂和方法。还提供了用于施用减毒细菌的试剂和方法，所述减毒细菌用于诱导针对肿瘤，癌细胞或感染剂的免疫应答。还提供了诊断和试剂盒的方法。

2. 发明专利

CA2049533A1 LPS-CONTAINING ANALGESICS AND VETERINARY ANALGESICS 未知
公开(公告)号：CA2049533A1
公开(公告)日：1992-02-21
申请号：CA2049533
申请日：1991-08-20
申请人： SOMA GENICHIRO , YOSHIMURA KIYOSHI , TSUKIOKA DAISUKI , MIZUNO DEN ICHI , OSHIMA HARUYUKI
发明人： SOMA GEN-ICHIRO , YOSHIMURA KIYOSHI , TSUKIOKA DAISUKE , MIZUNO DEN ICHI , OSHIMA HARUYUKI
IPC分类号： A61K35/74 , A61K45/00 , C12P19/04 , A61K31/70
摘要： of the disclosure An analgesic composition comprising an effective amount of at least one member of LPS whose macrophage activation ED50 is 0.4 - 100 ng/ml of culture solution in terms of its limulus testpositive LPS content observed on a sigmoid curve Prepared by determining the ability of the LPS to activate the TNF productivity of macrophage cultured in vitro, and plotting the macrophage activation ability (%) along the axis of ordinate wherein the ability is estimated to be 0 % in the case where it corresponds to the quantity of TNF produced by macrophage with no LPS added thereto, and 100 % is assigned to the macrophage activation ability which provides the maximal and constant quantity of TNF produced by the macrophage and plotting the limulus testpositive LPS content of the LPS along the axis of abscissa on a logarithmic scale, in admixture with a pharmaceutically or veterinarily acceptable carrier, such that when administered to an animal, high cholesterol level of said animal is prevented or cured; and a method of treating pain of an animal comprising administration to said animal an amount of the above composition effective to prevent or cure the pain of said animal. 77

3. 发明专利

CA2092621C STABILIZER FOR PHOSPHOLIPID VESICLES 未知
公开(公告)号：CA2092621C
公开(公告)日：2004-08-10
申请号：CA2092621
申请日：1993-03-12
申请人： SAITO AKAHISA , YOSHIMURA KIYOSHI , SUZUKI TAKANAO , TAKISADA MIKIMASA , TAKEOKA SHINJI , SAKAI HIROMI , TSUCHIDA HIDETOSHI
发明人： SAITO AKAHISA , YOSHIMURA KIYOSHI , SUZUKI TAKANAO , TAKISADA MIKIMASA , TAKEOKA SHINJI , SAKAI HIROMI , TSUCHIDA HIDETOSHI
IPC分类号： A61K9/127 , C07H15/04 , C07H15/06 , C07H15/10 , C07J17/00 , C07H13/04 , C08B37/00 , C07J41/00
摘要： An oligosaccharide lipid is provided which has 2 to 20 saccharide units, and has a hydrophobic group linked by an ether linkage to an anomer carbon on a reducing end group. A stabilizer for a phospholipid vesicle is also provided which comprises an oligosaccharide derivative having 2 to 20 saccharide units, and having a hydrophobic group linked by an amide linkage or an ether linkage to an anomer carbon on a reducing end group constituted of an aldose.

4. 发明专利

CA2092621A1 STABILIZER FOR PHOSPHOLIPID VESICLES 未知
公开(公告)号：CA2092621A1
公开(公告)日：1993-10-22
申请号：CA2092621
申请日：1993-03-12
申请人： SAITO AKAHISA , YOSHIMURA KIYOSHI , SUZUKI TAKANAO , TAKISADA MIKIMASA , TAKEOKA SHINJI , SAKAI HIROMI , TSUCHIDA HIDETOSHI
发明人： SAITO AKAHISA , YOSHIMURA KIYOSHI , SUZUKI TAKANAO , TAKISADA MIKIMASA , TAKEOKA SHINJI , SAKAI HIROMI , TSUCHIDA HIDETOSHI
IPC分类号： A61K9/127 , C07H15/04 , C07H15/06 , C07H15/10 , C07J17/00 , C07H13/04 , C08B37/00 , C07J41/00
摘要： An oligosaccharide lipid is provided which has 2 to 20 saccharide units, and has a hydrophobic group linked by an ether linkage to an anomer carbon on a reducing end group. A stabilizer for a phospholipid vesicle is also provided which comprises an oligosaccharide derivative having 2 to 20 saccharide units, and having a hydrophobic group linked by an amide linkage or an ether linkage to an anomer carbon on a reducing end group constituted of an aldose.

5. 发明专利

JP2006320593A OVERLAPPED PAD WITH TAKE-OUT HOLE OR DIAPER 审中-公开
公开(公告)号：JP2006320593A
公开(公告)日：2006-11-30
申请号：JP2005147522
申请日：2005-05-20
申请人： YOSHIMURA KIYOSHI
发明人： YOSHIMURA KIYOSHI
IPC分类号： A61F5/452 , A47K11/06 , A61F5/44 , A61F13/15
摘要： PROBLEM TO BE SOLVED: To facilitate the self-help of sanitarily exchanging a diaper by allowing feces not to easily touch skin and easily performing cleaning, so as to relieve care burden, and to provide a portable toilet for urgency in a place without toilet equipment. SOLUTION: A feces storage bag is formed of the bonded material of a flexible liquid absorbent permeable surface sheet and a liquid impermeable rear sheet. The cylinder part of the bag is accordion-folded. The hollow opening end of the part is stuck onto the inner side of the diaper with the hole, so as to obtain the diaper pad with the hole. While cleaning the feces on a buttock part or the surface of the pad, the pad is drawn out to a discharge port, and collected, discharged and closed in the shape of the reversed bag enclosed with the liquid impermeable rear sheet, without dirtying a hand. COPYRIGHT: (C)2007,JPO&INPIT

6. 发明专利

JPH0716078A LIGHTLY FRIED EGG COOKED IN FORM OF BEAN CURD AND ITS PRODUCTION 失效
公开(公告)号：JPH0716078A
公开(公告)日：1995-01-20
申请号：JP31983092
申请日：1992-11-30
申请人： YOSHIMURA KIYOSHI
发明人： YOSHIMURA KIYOSHI
IPC分类号： A23L11/00 , A23L15/00 , A23L1/32 , A23L1/20
摘要： PURPOSE:To obtain a lightly fried egg cooked in form of bean curd having excellent flavor, fragrance and pleasantness to the palate by frying egg cooked in the form of bean curd with an oil. CONSTITUTION:Hard lightly fried egg cooked in form of bean curd is coated with dogtooth violet starch, etc., and fried with a sesame oil. Egg cooked in the form of bean curd is produced hard in a completed state by stirring up egg diluted with stock for about 10 minutes while deaerating in a vadum container, removing foams, putting the deaerated egg in a basket steamer (mold), steaming, coagulating and dehydrating. The hard lightly fried egg cooked in form of bean curd is not coated with a binder for frying such as dogtooth violet starch and may be fried.

7. 发明专利

JPH0463531A WATER TANK FOR BREEDING ANIMAL AND VEGETABLE 失效
公开(公告)号：JPH0463531A
公开(公告)日：1992-02-28
申请号：JP17190090
申请日：1990-06-29
申请人： YOSHIMURA KIYOSHI
发明人： YOSHIMURA KIYOSHI
IPC分类号： A01K63/00 , A01K63/04
摘要： PURPOSE:To breed fish and small animal with little effort by connecting a water-suction pipe of a pump to a water-hole opened at a side part, etc., of a water tank, introducing air, etc., into a discharge pipe of the pump, connecting a closed air-water mixing chamber and opening an ejection port in the water tank. CONSTITUTION:Water is poured into a water tank 2 to an extent to almost submerge a water-hole in water. Water in the tank is sucked from the bottom by driving a pump 3, transferred to ejection pipes divided into two with a branch and ejected into the water tank through each ejection port to form a circulation path. The water passing through the 1st ejection pipe 5 is ejected to the upper part of a filter material through an ejection port placed in a filter 7 above the water tank, filtered and dropped from the discharging port on the water surface of the tank. When water is passed through the 2nd ejection pipe 8, air, etc., are sucked into the channel through an air hole 10 by the action of injector, joined with water and stirred. Air bubbles are discharged through an exhaust valve and water is exclusively discharged into the tank.

8. 发明专利

JPS558581A METAL MELTING FURNACE 失效
公开(公告)号：JPS558581A
公开(公告)日：1980-01-22
申请号：JP8242978
申请日：1978-07-05
申请人： YOSHIMURA KIYOSHI
发明人： YOSHIMURA KIYOSHI , HIGUCHI FUUGETSU
IPC分类号： F27B14/14 , C22C1/02

9. 发明专利

JP2001000026A LAWN MOWER AND BLADE UNIT OF LAWN MOWER 失效
公开(公告)号：JP2001000026A
公开(公告)日：2001-01-09
申请号：JP17041899
申请日：1999-06-17
申请人： YOSHIMURA KIYOSHI
发明人： YOSHIMURA KIYOSHI
IPC分类号： A01D34/53 , A01D34/02
摘要： PROBLEM TO BE SOLVED: To provide a lawn mower which can largely improve the recovery efficiency of cut lawn (wastes), and to provide the blade unit of the lawn mower. SOLUTION: A blade unit 2 is obtained by disposing blades 11 on the circumferential surface of a rotary shaft 10 and further disposing vanes 2 between the blades 11. When the blade unit 2 is rotated, a strong air flow is generated with the blades 11 and the vanes 12. Lawn wastes cut with the blades 11 and the fixed blades 13 are recovered into a recovery portion 3 by the use of the air flow.

10. 发明专利

JPH0857111A LAWN MAT 失效
公开(公告)号：JPH0857111A
公开(公告)日：1996-03-05
申请号：JP22574294
申请日：1994-08-25
申请人： YOSHIMURA KIYOSHI
发明人： YOSHIMURA KIYOSHI
IPC分类号： A01G13/00 , A63C19/00 , E01C13/00 , E01C13/08
摘要： PURPOSE: To provide a lawn mat which is placed in a golfer's walkway in a golf course and can be taken out from the ground and replaced in another place for the purpose of maintenance. CONSTITUTION: This lawn mat is made up of the first mat 11 and the second mat 21. The first and second mats are of the same shape and dimension, and the second mat 21 is overlaid on the first mat 11. Fitting depressions 23 mutually fittable are formed inn the intersections of the top side of the first mat 11 and the bottom side of the second mat 21. Holes 12 of the first mat 11 and holes 22 of the second mat 21 can be made larger than those of conventional mats. Therefore, since the amount and weight of grass which twine around the first mat 11 and the second mat 21 are low, it is easy to peel mats from the ground and replace them elsewhere.

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