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1. 发明申请

WO2011020873A1 IMPLANTABLE VASCULAR ACCESS 审中-公开
标题翻译：可植入血管通路
公开(公告)号：WO2011020873A1
公开(公告)日：2011-02-24
申请号：PCT/EP2010/062091
申请日：2010-08-19
申请人： CENDRES + MÉTAUX SA , SCHÜTZ, Daniel , GUENAT, Jean-Marc , AUDERSET, Adrian , STIEGER, Christof , FREY, Felix , HÄUSLER, Rudolf
发明人： SCHÜTZ, Daniel , GUENAT, Jean-Marc , AUDERSET, Adrian , STIEGER, Christof , FREY, Felix , HÄUSLER, Rudolf
IPC分类号： A61M1/00
CPC分类号： A61M39/0247 , A61M1/3653 , A61M1/3659 , A61M1/3661 , A61M39/26 , A61M2039/025
摘要： A transcutaneous implantable access port (1) for removal and/or return of fluids of a patient comprising: a fixation unit (3, 31, 33) adapted to be fixed to a bone (100) of the patient; a valve unit(5)comprising a sealing membrane (8) at its distal end and one or more chambers (51, 52) adjacent of said sealing membrane, the valve unit being detachably mounted on the fixation unit such that the distal end of the valve unit protrudes extracorporealy; an internal conduit (4) fluidly connectable to a vascular structure of the patient and releasably connectable to the valve unit such as to establish fluidic communication between the internal conduit and said one or more chambers; and an extracorporeal connecting member (23) having an end portion(74,75); wherein said extracorporeal connecting member is adapted to be connected to the distal end of the valve unit such that said end portion passes through said sealing membrane such as to open a fluidic passage between the connecting member and said one or several chambers and whereby said fluidic passage closes, when the connecting member is respectively connected to the access port and withdrawn therefrom. The access port disclosed herein can be used for high volume removal and/or return of blood or other fluids from the patient.
摘要翻译：一种用于移除和/或返回患者流体的经皮可植入进入口（1），包括：固定单元（3,31,33），其适于固定在患者的骨骼（100）上; 阀单元（5）在其远端包括密封膜（8）和与所述密封膜相邻的一个或多个腔室（51,52），所述阀单元可拆卸地安装在所述固定单元上，使得所述阀体阀门单元突出体外内部管道（4），其可流体地连接到患者的血管结构并且可释放地连接到所述阀单元，以便在所述内部管道和所述一个或多个腔室之间建立流体连通; 和具有端部（74,75）的体外连接构件（23）; 其中所述体外连接构件适于连接到所述阀单元的远端，使得所述端部穿过所述密封膜，以便在所述连接构件和所述一个或多个室之间打开流体通道，并且由此所述流体通道当连接构件分别连接到通道并从其中取出时关闭。本文公开的进入端口可用于来自患者的血液或其它流体的高体积移除和/或返回。

2. 发明申请

WO2011150978A1 IMPLANTED ACCESS PORT 审中-公开
标题翻译：嵌入式接口
公开(公告)号：WO2011150978A1
公开(公告)日：2011-12-08
申请号：PCT/EP2010/057860
申请日：2010-06-04
申请人： CENDRES+METAUX SA , SCHÜTZ, Daniel , GUENAT, Jean-Marc , AUDERSET, Adrian , MESSERLI, Hans , STIEGER, Christof , FREY, Felix , HÄUSLER, Rudolf
发明人： SCHÜTZ, Daniel , GUENAT, Jean-Marc , AUDERSET, Adrian , MESSERLI, Hans , STIEGER, Christof , FREY, Felix , HÄUSLER, Rudolf
IPC分类号： A61M39/02
CPC分类号： A61M39/285 , A61M39/0247 , A61M2039/0258 , A61M2039/0261 , A61M2039/0264 , A61M2039/027 , A61M2039/0276 , A61M2039/0282
摘要： An implantable access port (1) for removal and/or return of fluids to a patient, comprising: an internal conduit (3) adapted to be connected at its proximal end to the access port (1) and at its distal end to a vascular structure of the patient; an external conduit (5) adapted to be connected at its proximal end to the access port (1) and at its distal end to an extracorporeal device; and a transcutaneous coupling member (2) destined to be anchored in a tissue of the patient and comprising a first valve system (7) operable to be in an open or closed configuration to establish or block fluidic communication to and from the internal conduit (3); characterized in that the coupling member (2) further comprises a second valve system (8) adapted to be removably connected to the first valve system (7) and operable to be in an open or closed configuration to establish or block fluidic communication to and from the external conduit (5), such as to establish fluid communication between the internal and external conduits (3, 5) when the first and second valve systems (7, 8) are connected and in the open configuration.
摘要翻译：一种用于将流体去除和/或返回到患者的可植入进入口（1），包括：内部管道（3），其适于在其近端处连接到进入端口（1），并且在其远端处连接到血管患者结构; 适于在其近端处连接到进入端口（1）并且其远端处连接到体外装置的外部导管（5）; 以及旨在锚定在患者的组织中的经皮耦合构件（2），并且包括可操作以处于打开或闭合构造的第一阀系统（7），以建立或阻止与内部导管（3）的流体连通）; 其特征在于，所述联接构件（2）还包括适于可拆卸地连接到所述第一阀系统（7）并且可操作以处于打开或关闭构造的第二阀系统（8），以建立或阻止与外部管道（5），以便当第一和第二阀门系统（7,8）连接并且处于打开状态时，在内部和外部管道（3,5）之间建立流体连通。

3. 发明申请

WO2009103758A9 IMPLANTABLE ACCESS FOR REMOVAL AND/OR RETURN OF FLUIDS 审中-公开
公开(公告)号：WO2009103758A9
公开(公告)日：2009-08-27
申请号：PCT/EP2009/051967
申请日：2009-02-19
申请人： UNIVERSITAET BERN , HAEUSLER, Rudolf , FREY, Felix , STIEGER, Christof , ARNOLD, Andreas , FARESE, Stefan , UEHLINGER, Dominik
发明人： HAEUSLER, Rudolf , FREY, Felix , STIEGER, Christof , ARNOLD, Andreas , FARESE, Stefan , UEHLINGER, Dominik
IPC分类号： A61M1/00
摘要： Implantable access device (10) for removal and/or return of fluids to a patient, being an animal or human, comprising a casing (20) attached to an internal conduit (51) to be connected with a lumen of the patient, a connector (21) attached at the casing (20) and arranged for attachment of an external conduit (22) to the device (10), and an actuator unit (40) within the casing (20) to selectively allow or block the fluid communication between the internal conduit (51) and the external conduit (22); the device (10) further comprising a fixation unit (34, 35) integrated in or attached at the casing (20) arranged for fixation of the device (10) to a bone (1) of the patient; characterized in that the fixation unit (34, 35) extends axially along the longitudinal axis (100) of the device (10), and in that the internal conduit (51) comprises one or more tube lines (61, 62, 63) for a predetermined flow direction and the external conduit (22) comprises one or more separate access lines (71, 72, 73) for a predetermined flow direction.

4. 发明申请

WO2009103758A3 IMPLANTABLE ACCESS FOR REMOVAL AND/OR RETURN OF FLUIDS 审中-公开
公开(公告)号：WO2009103758A3
公开(公告)日：2009-08-27
申请号：PCT/EP2009/051967
申请日：2009-02-19
申请人： UNIVERSITAET BERN , HAEUSLER, Rudolf , FREY, Felix , STIEGER, Christof , ARNOLD, Andreas , FARESE, Stefan , UEHLINGER, Dominik
发明人： HAEUSLER, Rudolf , FREY, Felix , STIEGER, Christof , ARNOLD, Andreas , FARESE, Stefan , UEHLINGER, Dominik
IPC分类号： A61M1/00
摘要： Implantable access device (10) for removal and/or return of fluids to a patient, being an animal or human, comprising a casing (20) attached to an internal conduit (51) to be connected with a lumen of the patient, a connector (21) attached at the casing (20) and arranged for attachment of an external conduit (22) to the device (10), and an actuator unit (40) within the casing (20) to selectively allow or block the fluid communication between the internal conduit (51) and the external conduit (22); the device (10) further comprising a fixation unit (34, 35) integrated in or attached at the casing (20) arranged for fixation of the device (10) to a bone (1) of the patient; characterized in that the fixation unit (34, 35) extends axially along the longitudinal axis (100) of the device (10), and in that the internal conduit (51) comprises one or more tube lines (61, 62, 63) for a predetermined flow direction and the external conduit (22) comprises one or more separate access lines (71, 72, 73) for a predetermined flow direction.

5. 发明授权

EP2575951B1 IMPLANTED ACCESS PORT 有权
标题翻译：植入式访问端口
公开(公告)号：EP2575951B1
公开(公告)日：2015-10-07
申请号：EP10722113.7
申请日：2010-06-04
申请人： Cendres + Métaux SA
发明人： SCHÜTZ, Daniel , GUENAT, Jean-Marc , AUDERSET, Adrian , MESSERLI, Hans , STIEGER, Christof , FREY, Felix , HÄUSLER, Rudolf
IPC分类号： A61M39/02
CPC分类号： A61M39/285 , A61M39/0247 , A61M2039/0258 , A61M2039/0261 , A61M2039/0264 , A61M2039/027 , A61M2039/0276 , A61M2039/0282

6. 发明授权

EP2467177B1 Implantable vascular access 有权
标题翻译：植入血管通路
公开(公告)号：EP2467177B1
公开(公告)日：2014-12-03
申请号：EP10747184.9
申请日：2010-08-19
申请人： Cendres + Métaux SA
发明人： SCHÜTZ, Daniel , GUENAT, Jean-Marc , AUDERSET, Adrian , STIEGER, Christof , FREY, Felix , HÄUSLER, Rudolf
IPC分类号： A61M39/02 , A61M39/26 , A61M1/36
CPC分类号： A61M39/0247 , A61M1/3653 , A61M1/3659 , A61M1/3661 , A61M39/26 , A61M2039/025

7. 发明公开

EP2575951A1 IMPLANTED ACCESS PORT 有权
标题翻译：植入式访问端口
公开(公告)号：EP2575951A1
公开(公告)日：2013-04-10
申请号：EP10722113.7
申请日：2010-06-04
申请人： Cendres + Métaux SA
发明人： SCHÜTZ, Daniel , GUENAT, Jean-Marc , AUDERSET, Adrian , MESSERLI, Hans , STIEGER, Christof , FREY, Felix , HÄUSLER, Rudolf
IPC分类号： A61M39/02
CPC分类号： A61M39/285 , A61M39/0247 , A61M2039/0258 , A61M2039/0261 , A61M2039/0264 , A61M2039/027 , A61M2039/0276 , A61M2039/0282
摘要： An implantable access port (1) for removal and/or return of fluids to a patient, comprising: an internal conduit (3) adapted to be connected at its proximal end to the access port (1) and at its distal end to a vascular structure of the patient; an external conduit (5) adapted to be connected at its proximal end to the access port (1) and at its distal end to an extracorporeal device; and a transcutaneous coupling member (2) destined to be anchored in a tissue of the patient and comprising a first valve system (7) operable to be in an open or closed configuration to establish or block fluidic communication to and from the internal conduit (3); characterized in that the coupling member (2) further comprises a second valve system (8) adapted to be removably connected to the first valve system (7) and operable to be in an open or closed configuration to establish or block fluidic communication to and from the external conduit (5), such as to establish fluid communication between the internal and external conduits (3, 5) when the first and second valve systems (7, 8) are connected and in the open configuration.
摘要翻译： 1。一种用于将流体移除和/或返回到患者的可植入进入端口（1），包括：内部导管（3），其适于在其近端连接到进入端口（1）并且在其远端连接到血管病人的结构; 适于在其近端连接到所述进入端口（1）并且在其远端处连接到体外装置的外部导管（5）以及预定锚定在患者组织中并且包括第一阀系统（7）的经皮连接构件（2），所述第一阀系统（7）可操作以处于打开或关闭构型以建立或阻断流体连通至内部导管（3））; 其特征在于，所述联接构件（2）还包括第二阀系统（8），所述第二阀系统适于可拆卸地连接到所述第一阀系统（7）并且可操作以处于打开或关闭构型以建立或阻止流体通向和来自外部导管（5），例如当第一和第二阀门系统（7,8）连接并且处于打开构造时建立内部和外部导管（3,5）之间的流体连通。

8. 发明公开

EP2467177A1 IMPLANTABLE VASCULAR ACCESS 有权
标题翻译： ImplantierbarerGefäßzugang
公开(公告)号：EP2467177A1
公开(公告)日：2012-06-27
申请号：EP10747184.9
申请日：2010-08-19
申请人： Cendres + Métaux SA
发明人： SCHÜTZ, Daniel , GUENAT, Jean-Marc , AUDERSET, Adrian , STIEGER, Christof , FREY, Felix , HÄUSLER, Rudolf
IPC分类号： A61M1/00
CPC分类号： A61M39/0247 , A61M1/3653 , A61M1/3659 , A61M1/3661 , A61M39/26 , A61M2039/025
摘要： A transcutaneous implantable access port (1) for removal and/or return of fluids of a patient comprising: a fixation unit (3, 31, 33) adapted to be fixed to a bone (100) of the patient; a valve unit(5)comprising a sealing membrane (8) at its distal end and one or more chambers (51, 52) adjacent of said sealing membrane, the valve unit being detachably mounted on the fixation unit such that the distal end of the valve unit protrudes extracorporealy; an internal conduit (4) fluidly connectable to a vascular structure of the patient and releasably connectable to the valve unit such as to establish fluidic communication between the internal conduit and said one or more chambers; and an extracorporeal connecting member (23) having an end portion(74,75); wherein said extracorporeal connecting member is adapted to be connected to the distal end of the valve unit such that said end portion passes through said sealing membrane such as to open a fluidic passage between the connecting member and said one or several chambers and whereby said fluidic passage closes, when the connecting member is respectively connected to the access port and withdrawn therefrom. The access port disclosed herein can be used for high volume removal and/or return of blood or other fluids from the patient.

9. 发明申请

WO2004085731A1 PRÜFMITTEL ZUR STANDARDISIERTEN FESTSTELLUNG DER QUALITÄT EINES WASCH-, REINIGUNGS- UND/ODER TROCKNUNGSPROZESSES 审中-公开
标题翻译：测试设备标准化确定洗涤，清洁和/或干燥过程的质量
公开(公告)号：WO2004085731A1
公开(公告)日：2004-10-07
申请号：PCT/IB2004/000829
申请日：2004-03-22
申请人： EMPA TESTMATERIALIEN AG , FÄH, Daniel , FREY, Felix
发明人： FÄH, Daniel , FREY, Felix
IPC分类号： D06F39/00
CPC分类号： D06F35/005 , A47L15/42 , D06F39/00
摘要： Ein Kerngedanke der Erfindung besteht darin, ein definiertes Prüfmittel zu schaffen, auf dem entsprechende Partikel in bestimmter Dichte aufgebracht sind. Bei Waschmaschinen wird insbesondere durch die mechanische Belastung des Prüfmittels innerhalb der Trommel, beispielsweise durch Walken, Biegen oder Strecken erreicht, dass sich die Partikel von dem Prüfmittel lösen. Durch die physikalischen und/oder chemische Bearbeitung des Prüfmittels innerhalb einer Spülmaschine, beispielsweise durch unterschiedliche Wasserstrahlen mit unterschiedlichen Drücken sowie den chemischen Zusätzen wird erreicht, dass sich die Partikel von dem Prüfmittel lösen. Die Anzahl der Partikel, die nach dem Reinigungs-, Wasch- und/oder Trocknungsvorgang auf dem Prüfmittel verbleiben, ist eine Grösse, die in einem Verhältnis zur Belastung des Prüfmittels bzw. zur Reinigungsqualität und damit zur physikalischen und/oder chemischen Aktivität des Aggregats während des Reinigungs-, Wasch- und/oder Trocknungsvorgangs steht. Das Prüfmittel zur standardisierten Feststellung der Qualität eines Wasch-, Reinigungs- und/oder Trocknungsprozesses lässt sich auf jedes Aggregat anwenden, das zumin einen der gennanten Prozesse durchführt. Waschmaschine und Spülmaschine stellen somit nur eine Auswahl dar.
摘要翻译：本发明的核心思想是提供一种定义的检测设备，在一定的密度被施加到相应的颗粒。在洗衣机中尤其通过测试的机械负载实现步行，弯曲或伸展，从测试设备释放所述颗粒是指在滚筒内，例如。由测试装置在洗碗机中的物理和/或化学处理，例如通过在不同压力下的水射流不同，以及化学添加剂实现了释放来自该测试设备的颗粒。清洗，洗涤和/或干燥过程后残留在测试颗粒的数目是指，具有一定的大小，虽然在一个比对测试剂的负载或清洗质量并因此聚集体的物理和/或化学活性清洗，洗涤和/或干燥过程。测试设备用于洗涤的质量标准化的求取，清洗和/或干燥过程可以施加到每个单元，其执行在gennanten过程之一。因此洗衣机和洗碗机仅构成一个选择。

10. 发明申请

WO2009103758A2 IMPLANTABLE ACCESS FOR REMOVAL AND/OR RETURN OF FLUIDS 审中-公开
标题翻译：可移除的访问流体和/或返回流体
公开(公告)号：WO2009103758A2
公开(公告)日：2009-08-27
申请号：PCT/EP2009/051967
申请日：2009-02-19
申请人： UNIVERSITAET BERN , HAEUSLER, Rudolf , FREY, Felix
发明人： HAEUSLER, Rudolf , FREY, Felix
IPC分类号： A61M1/00
CPC分类号： A61M39/0247 , A61M1/3653 , A61M1/3655 , A61M2039/025 , A61M2039/0261 , A61M2039/027 , A61M2039/0276 , A61M2039/0282
摘要： Implantable access device (10) for removal and/or return of fluids to a patient, being an animal or human, comprising a casing (20) attached to an internal conduit (51) to be connected with a lumen of the patient, a connector (21) attached at the casing (20) and arranged for attachment of an external conduit (22) to the device (10), and an actuator unit (40) within the casing (20) to selectively allow or block the fluid communication between the internal conduit (51) and the external conduit (22); the device (10) further comprising a fixation unit (34, 35) integrated in or attached at the casing (20) arranged for fixation of the device (10) to a bone (1) of the patient; characterized in that the fixation unit (34, 35) extends axially along the longitudinal axis (100) of the device (10), and in that the internal conduit (51) comprises one or more tube lines (61, 62, 63) for a predetermined flow direction and the external conduit (22) comprises one or more separate access lines (71, 72, 73) for a predetermined flow direction.
摘要翻译：用于将流体移除和/或返回到作为动物或人的患者的可植入进入装置（10），包括附接到与患者的内腔连接的内部导管（51）的壳体（20），连接器（21），其安装在所述壳体（20）处并且被布置成用于将外部导管（22）附接到所述装置（10）;以及在所述壳体（20）内的致动器单元（40），以选择性地允许或阻止内部管道（51）和外部管道（22）; 所述装置（10）还包括集成在所述壳体（20）中或附接在所述壳体（20）上的固定单元（34,35），所述固定单元布置成用于将所述装置（10）固定到所述患者的骨头（1）其特征在于，所述固定单元（34,35）沿着所述装置（10）的纵向轴线（100）轴向延伸，并且所述内部导管（51）包括一条或多条管线（61,62,63），用于预定的流动方向，并且外部导管（22）包括用于预定流动方向的一个或多个单独的进入管线（71,72,73）。

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