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1. 发明申请

WO2011011104A1 VENTRICULAR SHUNT SYSTEM AND METHOD 审中-公开
标题翻译：通气管系统及方法
公开(公告)号：WO2011011104A1
公开(公告)日：2011-01-27
申请号：PCT/US2010/033396
申请日：2010-05-03
申请人： CARDIOMEMS, INC. , YADEV, Jay, S. , CROS, Florent
发明人： YADEV, Jay, S. , CROS, Florent
IPC分类号： A61M25/088 , A61B5/027 , A61M39/22
CPC分类号： G01F15/066 , A61B5/0031 , A61B5/031 , A61B5/05 , A61B5/076 , A61B5/6846 , A61B2560/0219 , A61B2560/0223 , A61M27/006 , G01R23/12 , G01R23/145 , H01Q7/00
摘要： A ventricular shunt systems and methods of preventing hydrocephalus are described herein. In one aspect, the ventricular shunt system has at least one pressure sensor that is configured to be selectively electromagnetically coupled to an ex-vivo source of RF energy and is variable in response to the pressure in a patient's ventricle.
摘要翻译：本文描述了心室分流系统和预防脑积水的方法。在一个方面，心室分流系统具有至少一个压力传感器，其被配置为选择性地电磁耦合到离体RF能量源，并且响应于患者心室中的压力是可变的。

2. 发明申请

WO2011060359A3 SELECTIVELY ACTUATING WIRELESS, PASSIVE IMPLANTABLE SENSOR 审中-公开
标题翻译：选择性地启动无线，被动植入式传感器
公开(公告)号：WO2011060359A3
公开(公告)日：2011-05-19
申请号：PCT/US2010/056709
申请日：2010-11-15
申请人： CARDIOMEMS, INC. , CROS, Florent
发明人： CROS, Florent
IPC分类号： A61B5/053 , A61B5/04
摘要： A wireless sensor having a primary passive electrical resonant circuit that has an intrinsic electrical property that is variable in response to a characteristic of a patient and a secondary passive electrical resonant circuit. In one aspect, the primary passive resonant circuit can be positioned into a tuned position in response to the actuation of the secondary passive electrical resonant circuit. In a further aspect, in the tuned position, the primary passive electrical resonant circuit, in response to an energizing signal produced by an ex- vivo source of RF energy, is configured to generate a sensor signal characterized by a resonant frequency that is indicative of the characteristic.
摘要翻译：具有主无源电谐振电路的无线传感器具有响应于患者和次级无源电谐振电路的特性而可变的固有电特性。在一个方面中，响应于次级无源电谐振电路的致动，初级无源谐振电路可以被定位在调谐位置中。在另一方面，在调谐位置，主无源电谐振电路响应于由射频能量的离体源产生的激励信号而被配置为产生传感器信号，该传感器信号的特征在于表示谐振频率特点。

3. 发明申请

WO2008051907A1 METHOD AND APPARATUS FOR MEASURING PRESSURE INSIDE A FLUID SYSTEM 审中-公开
标题翻译：用于测量流体内部压力的方法和装置
公开(公告)号：WO2008051907A1
公开(公告)日：2008-05-02
申请号：PCT/US2007/082092
申请日：2007-10-22
申请人： CardioMEMS, Inc. , CROS, Florent , CORCORAN, Kevin , BERR, Miguel Luis
发明人： CROS, Florent , CORCORAN, Kevin , BERR, Miguel Luis
IPC分类号： A61B5/00 , A61B5/0215 , A61B5/07
CPC分类号： A61B5/076 , A61B5/0031 , A61B5/0215
摘要： A disclosed method determines fluid pressure inside a vessel without compromising the integrity of the vessel. A sensor is positioned in operative communication with the external wall of the vessel such that expansion of the external wall of the vessel exerts a force against the sensor that is directed substantially radially outward with respect to the vessel. A substantially radially inward force is caused to be directed against the sensor in response to the substantially radially outward force exerted by the external vessel wall. The sensor can thus be used to detect the magnitude of the substantially radially outward force. A disclosed apparatus determines fluid pressure inside a vessel without compromising the integrity of the vessel. The apparatus includes a sensor and a band operatively associated with the sensor and configured to at least partially encircle the vessel so as to retain the sensor in operative communication against the external wall of the vessel.
摘要翻译：所公开的方法确定容器内的流体压力而不损害容器的完整性。传感器被定位成与容器的外壁可操作地连通，使得容器的外壁的膨胀对传感器施加相对于容器大致径向向外的力。响应于由外部血管壁施加的基本径向向外的力，基本上径向向内的力被引导抵靠传感器。因此，传感器可用于检测基本径向向外的力的大小。所公开的装置确定容器内的流体压力而不损害容器的完整性。该装置包括传感器和与传感器可操作地相关联的带，并被配置为至少部分地环绕容器，以便将传感器保持在与血管的外壁有效连通的位置。

4. 发明申请

WO2010011612A1 PHYSICAL PROPERTY SENSOR WITH ACTIVE ELECTRONIC CIRCUIT AND WIRELESS POWER AND DATA TRANSMISSION 审中-公开
标题翻译：与有源电子电路和无线供电和数据传输的物理特性传感器
公开(公告)号：WO2010011612A1
公开(公告)日：2010-01-28
申请号：PCT/US2009/051177
申请日：2009-07-20
申请人： CARDIOMEMS, INC. , PARK, Jin, Woo , CROS, Florent , ALLEN, Mark, G.
发明人： PARK, Jin, Woo , CROS, Florent , ALLEN, Mark, G.
IPC分类号： A61B5/00
CPC分类号： H02J50/00 , A61B5/0031 , A61B2560/0219 , G01K13/00 , G01L1/00 , G01L7/00 , H02J5/005 , H02J7/025
摘要： Wireless sensors configured to record and transmit data as well as sense and, optionally, actuate to monitor physical properties of an environment and, optionally, effect changes within that environment, m one aspect, the wireless sensor can have a power harvesting unit; a voltage regulation unit, a transducing oscillator unit, and a transmitting coil. The voltage regulation unit is electrically coupled to the power harvesting unit and is configured to actuate at a minimum voltage level. The transducing oscillator unit is electrically coupled to the voltage regulation unit and is configured to convert a sensed physical property into an electrical signal. Also, the transmitting coil is configured to receive the electrical signal and to transmit the electrical signal to an external antenna.
摘要翻译：被配置为记录和发送数据以及感和，可选地，致动监测的环境的物理性质和任选的无线传感器，该环境中的效果的变化，米一个方面中，无线传感器可以具有电力获取单元; 电压调节单元，换能振荡器单元，和一个发射线圈。电压调节单元电耦合到功率采集单元并且被配置为在最小电压电平下致动。转换振荡器单元电耦合到电压调节单元，并且被配置为将检测到的物理特性转换成电信号。此外，发送线圈被配置为接收电信号并将电信号发送到外部天线。

5. 发明申请

WO2006086113A3 HERMETIC CHAMBER WITH ELECTRICAL FEEDTHROUGHS 审中-公开
公开(公告)号：WO2006086113A3
公开(公告)日：2006-08-17
申请号：PCT/US2006/001095
申请日：2006-01-13
申请人： CARDIOMEMS, INC. , O'BRIAN, David , CROS, Florent , PARK, Jin Woo , FONSECA, Michael , YOU, Liang , ALLEN, Mark
发明人： O'BRIAN, David , CROS, Florent , PARK, Jin Woo , FONSECA, Michael , YOU, Liang , ALLEN, Mark
IPC分类号： G01L7/00
摘要： A pressure cavity is durable, stable, and biocompatible and configured in such a way that it constitutes pico to nanoliter-scale volume. The pressure cavity is hermetically sealed from the exterior environment while maintaining the ability to communicate with other devices. Micromachined, hermetically-sealed sensors are configured to receive power and return information through direct electrical contact with external electronics. The pressure cavity and sensor components disposed therein are hermetically sealed from the ambient in order to reduce drift and instability within the sensor. The sensor is designed for harsh and biological environments, e.g. intracorporeal implantation and in vivo use. Additionally, novel manufacturing methods are employed to construct the sensors.

6. 发明申请

WO2009146090A1 STRAIN MONITORING SYSTEM AND APPARATUS 审中-公开
标题翻译：应变监测系统和装置
公开(公告)号：WO2009146090A1
公开(公告)日：2009-12-03
申请号：PCT/US2009/039222
申请日：2009-04-01
申请人： CARDIOMEMS, INC. , KROH, Jason , CROS, Florent , COURCIMAULT, Christophe
发明人： KROH, Jason , CROS, Florent , COURCIMAULT, Christophe
IPC分类号： A61B5/00 , G01L1/20
CPC分类号： G01L9/0073 , A61B5/0031 , A61B5/076 , A61B5/1116 , A61B5/4504 , A61B5/686 , A61B17/7002 , A61B2017/00221 , A61B2560/0219 , A61B2560/0223 , A61B2562/0261 , G01F15/066 , G01L1/14 , H01Q7/00
摘要： This application relates to an apparatus and system for sensing strain on a portion of an implant positioned in a living being. In one aspect, the apparatus has at least one sensor assembly that can be mountable thereon a portion of the implant and that has a passive electrical resonant circuit that can be configured to be selectively electromagnetically coupled to an ex-vivo source of RF energy. Each sensor assembly, in response to the electromagnetic coupling, can be configured to generate an output signal characterized by a frequency that is dependent upon urged movement of a portion of the passive electrical resonant circuit and is indicative of strain applied thereon a portion of the respective sensor assembly.
摘要翻译：本申请涉及用于感测定位在生物体内的植入物的一部分上的应变的装置和系统。在一个方面，该装置具有至少一个传感器组件，其可以安装在其上的植入物的一部分上，并且具有无源电谐振电路，其可被配置为选择性地电磁耦合到离体RF能量源。响应于电磁耦合，每个传感器组件可被配置成产生一个输出信号，该输出信号的特征在于一个频率，该频率取决于无源电谐振电路的一部分被激励的移动，并且指示在其上施加相应的一部分的应变传感器组件。

7. 发明申请

WO2009146089A2 SYSTEM AND APPARATUS FOR IN-VIVO ASSESSMENT OF RELATIVE POSITION OF AN IMPLANT 审中-公开
标题翻译：用于内生植入物相对位置的体内评估的系统和装置
公开(公告)号：WO2009146089A2
公开(公告)日：2009-12-03
申请号：PCT/US2009/039220
申请日：2009-04-01
申请人： CARDIOMEMS, INC. , KROH, Jason , CROS, Florent , COURCIMAULT, Christophe
发明人： KROH, Jason , CROS, Florent , COURCIMAULT, Christophe
IPC分类号： A61B17/70 , A61F2/44 , A61B18/18
CPC分类号： G01L9/0073 , A61B5/0031 , A61B5/076 , A61B5/1116 , A61B5/4504 , A61B5/686 , A61B17/7002 , A61B2017/00221 , A61B2560/0219 , A61B2560/0223 , A61B2562/0261 , G01F15/066 , G01L1/14 , H01Q7/00
摘要： A system and apparatus for providing an in- vivo assessment of relative movement of an implant that is positioned in a living being is provided that comprises a first assembly and a second assembly that are positioned within the living being. The first assembly comprises a passive electrical resonant circuit that is configured to be selectively electromagnetically coupled to an ex-vivo source of RF energy and, in response to the electromagnetic coupling, generates an output signal characterized by a frequency that is dependent upon a distance between the first assembly and the second assembly at the time of the electromagnetic coupling.
摘要翻译：提供了一种系统和装置，用于提供定位在活体中的植入物的相对运动的体内评估，该植入物包括位于生物体内的第一组件和第二组件。第一组件包括无源电谐振电路，其被配置为选择性地电磁耦合到离体RF能量源，并且响应于电磁耦合，产生以由频率表示的频率的输出信号，该频率取决于第一组件和第二组件在电磁耦合时。

8. 发明申请

WO2007002225A2 IMPLANTABLE WIRELESS SENSOR FOR IN VIVO PRESSURE MEASUREMENT 审中-公开
标题翻译：用于体内压力测量的可植入式无线传感器
公开(公告)号：WO2007002225A2
公开(公告)日：2007-01-04
申请号：PCT/US2006/024185
申请日：2006-06-21
申请人： CARDIOMEMS, INC. , O'BRIEN, David , WHITE, Jason , FONSECA, Michael , CROS, Florent , KROH, Jason , STERN, David , ALLEN, Mark
发明人： O'BRIEN, David , WHITE, Jason , FONSECA, Michael , CROS, Florent , KROH, Jason , STERN, David , ALLEN, Mark
CPC分类号： A61B5/0031 , A61B5/0215 , A61B5/076 , A61B2560/0219 , A61B2562/028
摘要： A sensor suitable for in vivo implantation has a capacitive circuit and a three-dimensional inductor coil connected to the capacitive circuit to form an LC circuit. The LC circuit is hermetically encapsulated within an electrically insulating housing. An electrical characteristic of the LC circuit is responsive to a change in an environmental parameter.
摘要翻译：适用于体内植入的传感器具有电容电路和连接到电容电路的三维电感线圈，以形成LC电路。 LC电路气密地封装在电绝缘壳体内。 LC电路的电气特性响应于环境参数的变化。

9. 发明申请

WO2007002185A3 METHOD OF MANUFACTURING IMPLANTABLE WIRELESS SENSOR FOR IN VIVO PRESSURE MEASUREMENT 审中-公开
公开(公告)号：WO2007002185A3
公开(公告)日：2007-01-04
申请号：PCT/US2006/024126
申请日：2006-06-21
申请人： CARDIOMEMS, INC. , O'BRIEN, David , ABERCROMBIE, Matthew , FONSECA, Michael , CROS, Florent , PARK, Jin Woo , SINGH, Angad
发明人： O'BRIEN, David , ABERCROMBIE, Matthew , FONSECA, Michael , CROS, Florent , PARK, Jin Woo , SINGH, Angad
IPC分类号： A61B5/0215 , A61B5/07 , G01L9/00
摘要： A method of manufacturing a sensor for in vivo applications includes the steps of providing two wafers of an electrically insulating material. A recess is formed in the first wafer, and a capacitor plate is formed in the recess of the first wafer. A second capacitor plate is formed in a corresponding region of the second wafer, and the two wafers are affixed to one another such that the first and second capacitor plates are arranged in parallel, spaced-apart relation.

10. 发明申请

WO2006086114A3 METHOD OF MANUFACTURING A HERMETIC CHAMBER WITH ELECTRICAL FEEDTHROUGHS 审中-公开
公开(公告)号：WO2006086114A3
公开(公告)日：2006-08-17
申请号：PCT/US2006/001101
申请日：2006-01-13
申请人： CARDIOMEMS, INC. , O'BRIAN, David , CROS, Florent , PARK, Jin Woo , FONSECA, Michael , YOU, Liang , ALLEN, Mark
发明人： O'BRIAN, David , CROS, Florent , PARK, Jin Woo , FONSECA, Michael , YOU, Liang , ALLEN, Mark
IPC分类号： H01L21/66 , H01L21/00 , H01L21/44 , H01L21/50 , H01L23/02
摘要： A method of manufacturing a hermetically-sealed chamber with an electrical feedthrough includes the step of hermetically fixing an electrode to a substrate in a predetermined location on the substrate. A passage is formed through the substrate through the predetermined location such that at least a portion of the electrode is exposed to the passage. The passage is then at least partially filled with an electrically conductive material. A housing is then formed including the substrate such that the housing defines a chamber, with the electrode being disposed within the housing and the chamber being hermetically sealed. The electrode within the chamber can be placed in electrical communication with an exterior electrical component by way of the electrically conductive material in the passage.

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