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1. 发明申请

WO2008031095A1 PHYSIOLOGICAL DATA ACQUISITION AND MANAGEMENT SYSTEM FOR USE WITH AN IMPLANTED WIRELESS SENSOR 审中-公开
标题翻译：生理数据采集和管理系统，用于带有无线传感器
公开(公告)号：WO2008031095A1
公开(公告)日：2008-03-13
申请号：PCT/US2007/078027
申请日：2007-09-10
申请人： CARDIOMEMS, INC. , RUTKOWSKI, Kim , MILLER, Donald, J. , KROH, Jason , BROGDON, Shawn, Michael , MOORE, Erik
发明人： RUTKOWSKI, Kim , MILLER, Donald, J. , KROH, Jason , BROGDON, Shawn, Michael , MOORE, Erik
IPC分类号： H04B5/00 , A61B5/00 , G01R33/00 , H04B5/02
CPC分类号： H04B5/02 , A61B5/0031 , A61B2560/0219 , H04B5/0043 , H04B5/0087
摘要： Aspects and embodiments of the present invention provide a system for obtaining, processing and managing data from an implanted sensor. In some embodiments, a patient or other persons can use a flexible antenna to obtain data from the implanted sensor. The flexible antenna includes at least one transmit loop and at least one receive loop. The transmit loop is adapted to propagate energizing signals to the implanted sensor. The receive loop is adapted to detect a response signal from the implanted sensor. The transmit loop includes a capacitor formed by a discontinuous area. The capacitor is adapted to allow the loop to be tuned. The flexible antenna can communicate with a patient device that collects the data from the implanted sensor, creates a data file and transmits the data file to a remote server over a network. A physician or other authorized person may access the remote server using an access device.
摘要翻译：本发明的方面和实施例提供了一种用于从植入的传感器获得，处理和管理数据的系统。在一些实施例中，患者或其他人可以使用柔性天线从植入的传感器获得数据。柔性天线包括至少一个发射环路和至少一个接收环路。发射环路适于将激励信号传播到植入的传感器。接收环路适于检测来自植入传感器的响应信号。发射环路包括由不连续区域形成的电容器。电容器适于允许调谐环路。柔性天线可以与从植入的传感器收集数据的患者设备进行通信，创建数据文件，并通过网络将数据文件发送到远程服务器。医生或其他授权人员可以使用访问设备访问远程服务器。

2. 发明申请

WO2008031011A1 ANTENNA CABLE 审中-公开
标题翻译：天线
公开(公告)号：WO2008031011A1
公开(公告)日：2008-03-13
申请号：PCT/US2007/077847
申请日：2007-09-07
申请人： CARDIOMEMS, INC. , MILLER, Donald, J. , KROH, Jason
发明人： MILLER, Donald, J. , KROH, Jason
IPC分类号： H01B11/20
CPC分类号： H01B11/203 , H01B7/0861
摘要： Embodiments of the present invention are directed to a cable assembly that is adapted to be connected to an antenna and a base unit. The cable assembly may be relatively flat with shielding and structures to reduce ground currents or other interference. Embodiments of the cable assembly include at least two coaxial cables for transmit and receive signals that are separated to reduce crosstalk or other interference. The cable may also include one or more inner cables, such as differential or switching pairs, between the two coaxial cables to provide cables for control, power, switching, or other functions. The inner cables may be positioned in parallel to each other and to each of the coaxial cables. In some embodiments, the inner cables include a first inner cable located at a first end of the inner cables and a second inner cable located at a second end of the inner cables. One coaxial cable may be positioned adjacent and parallel to the first inner cable, which the other coaxial cable may be positioned adjacent and parallel to the second inner cable.
摘要翻译：本发明的实施例涉及一种适于连接到天线和基座单元的电缆组件。电缆组件可以相对平坦，具有屏蔽和结构以减少接地电流或其它干扰。电缆组件的实施例包括用于发射和接收被分离以减少串扰或其他干扰的信号的至少两根同轴电缆。电缆还可以包括在两个同轴电缆之间的一个或多个内部电缆，例如差分或开关对，以提供用于控制，电力，开关或其他功能的电缆。内部电缆可以彼此平行并且与各个同轴电缆定位。在一些实施例中，内部电缆包括位于内部电缆的第一端的第一内部电缆和位于内部电缆的第二端的第二内部电缆。一个同轴电缆可以被定位成与第一内部电缆相邻并平行，另一个同轴电缆可以被定位成与第二内部电缆相邻并且平行。

3. 发明申请

WO2007030489A1 PREVENTING FALSE LOCKS IN A SYSTEM THAT COMMUNICATES WITH AN IMPLANTED WIRELESS SENSOR 审中-公开
标题翻译：防止在带有无线传感器的通信系统中使用虚假锁
公开(公告)号：WO2007030489A1
公开(公告)日：2007-03-15
申请号：PCT/US2006/034641
申请日：2006-09-06
申请人： CARDIOMENS, INC. , POWERS, Richard , ELLIS, Michael, G. , KROH, Jason , MILLER, Donald, J.
发明人： POWERS, Richard , ELLIS, Michael, G. , KROH, Jason , MILLER, Donald, J.
IPC分类号： A61B5/00 , G08C17/04 , G01L9/12 , G01D5/241
CPC分类号： A61B5/02014 , A61B5/0031 , A61B5/0215 , A61B5/076 , A61B5/726 , A61B2560/0223 , G01D21/00
摘要： The present invention determines the resonant frequency of a wireless sensor by adjusting the phase and frequency of an energizing signal until the frequency of the energizing signal matches the resonant frequency of the sensor. The system energizes the sensor with a low duty cycle, gated burst of RF energy having a predetermined frequency. The system receives the ring down response of the sensor and determines the resonant frequency of the sensor, which is used to calculate a physical parameter. The system uses a pair of phase locked loops to adjust the phase and the frequency of the energizing signal. The system identifies false locks by detecting an unwanted beat frequency in the coupled signal, as well as determining whether the coupled signal exhibits pulsatile characteristics that correspond to blood pressure.
摘要翻译：本发明通过调节通电信号的相位和频率直到通电信号的频率与传感器的谐振频率相匹配来确定无线传感器的谐振频率。该系统以低占空比激励传感器，具有预定频率的RF能量门控突发。系统接收传感器的响铃响应，并确定用于计算物理参数的传感器的谐振频率。该系统使用一对锁相环来调节激励信号的相位和频率。该系统通过检测耦合信号中的不期望的拍频来识别假锁，以及确定耦合信号是否表现出对应于血压的脉动特性。

4. 发明申请

WO2007008493A1 COUPLING LOOP, CABLE ASSEMBLY AND METHOD FOR POSITIONING COUPLING LOOP 审中-公开
标题翻译：耦合环，电缆组件和定位耦合环路的方法
公开(公告)号：WO2007008493A1
公开(公告)日：2007-01-18
申请号：PCT/US2006/026015
申请日：2006-06-30
申请人： CARDIOMEMS, INC. , KROH, Jason , ELLIS, Michael , MILLER, Donald , REFERMAT, Robert
发明人： KROH, Jason , ELLIS, Michael , MILLER, Donald , REFERMAT, Robert
IPC分类号： H04B5/00 , A61B5/00 , G01R33/00
CPC分类号： A61B5/02014 , A61B5/0031 , A61B5/064 , A61B5/07 , A61B2560/0219 , H01B11/20 , H04B5/0043 , Y10S128/903
摘要： A coupling loop or antenna is provided that can be used with a system that determines the resonant frequency of a sensor by adjusting the phase and frequency of an energizing signal until the frequency of the energizing signal matches the resonant frequency of the sensor. The coupling loop includes multiple loops. Preferably two tuned loops are used for transmitting the energizing signal to the sensor and an un-tuned loop is used for receiving the sensor signal from the sensor. A cable attached to the coupling loop provides maximum isolation between the energizing signal and the sensor signal by maximizing the distance between the coaxial cables that carry the signals and maintaining the relative positions of the coaxial cables throughout the cable assembly. Orientation features on the housing for the coupling loop and the sensor are provided to assist in positioning the coupling loop relative to the sensor to maximize the coupling between the sensor signal and the coupling loop.
摘要翻译：提供耦合环路或天线，其可以与通过调节激励信号的相位和频率来确定传感器的谐振频率的系统一起使用，直到通电信号的频率与传感器的谐振频率匹配。耦合回路包括多个回路。优选地，两个调谐回路用于将激励信号传输到传感器，并且未调谐回路用于从传感器接收传感器信号。连接到耦合回路的电缆通过使承载信号的同轴电缆之间的距离最大化并且保持同轴电缆在整个电缆组件中的相对位置来提供激励信号和传感器信号之间的最大隔离。提供用于耦合回路和传感器的壳体上的定向特征以帮助相对于传感器定位耦合回路，以使传感器信号和耦合回路之间的耦合最大化。

5. 发明申请

WO2009146090A1 STRAIN MONITORING SYSTEM AND APPARATUS 审中-公开
标题翻译：应变监测系统和装置
公开(公告)号：WO2009146090A1
公开(公告)日：2009-12-03
申请号：PCT/US2009/039222
申请日：2009-04-01
申请人： CARDIOMEMS, INC. , KROH, Jason , CROS, Florent , COURCIMAULT, Christophe
发明人： KROH, Jason , CROS, Florent , COURCIMAULT, Christophe
IPC分类号： A61B5/00 , G01L1/20
CPC分类号： G01L9/0073 , A61B5/0031 , A61B5/076 , A61B5/1116 , A61B5/4504 , A61B5/686 , A61B17/7002 , A61B2017/00221 , A61B2560/0219 , A61B2560/0223 , A61B2562/0261 , G01F15/066 , G01L1/14 , H01Q7/00
摘要： This application relates to an apparatus and system for sensing strain on a portion of an implant positioned in a living being. In one aspect, the apparatus has at least one sensor assembly that can be mountable thereon a portion of the implant and that has a passive electrical resonant circuit that can be configured to be selectively electromagnetically coupled to an ex-vivo source of RF energy. Each sensor assembly, in response to the electromagnetic coupling, can be configured to generate an output signal characterized by a frequency that is dependent upon urged movement of a portion of the passive electrical resonant circuit and is indicative of strain applied thereon a portion of the respective sensor assembly.
摘要翻译：本申请涉及用于感测定位在生物体内的植入物的一部分上的应变的装置和系统。在一个方面，该装置具有至少一个传感器组件，其可以安装在其上的植入物的一部分上，并且具有无源电谐振电路，其可被配置为选择性地电磁耦合到离体RF能量源。响应于电磁耦合，每个传感器组件可被配置成产生一个输出信号，该输出信号的特征在于一个频率，该频率取决于无源电谐振电路的一部分被激励的移动，并且指示在其上施加相应的一部分的应变传感器组件。

6. 发明申请

WO2009146089A2 SYSTEM AND APPARATUS FOR IN-VIVO ASSESSMENT OF RELATIVE POSITION OF AN IMPLANT 审中-公开
标题翻译：用于内生植入物相对位置的体内评估的系统和装置
公开(公告)号：WO2009146089A2
公开(公告)日：2009-12-03
申请号：PCT/US2009/039220
申请日：2009-04-01
申请人： CARDIOMEMS, INC. , KROH, Jason , CROS, Florent , COURCIMAULT, Christophe
发明人： KROH, Jason , CROS, Florent , COURCIMAULT, Christophe
IPC分类号： A61B17/70 , A61F2/44 , A61B18/18
CPC分类号： G01L9/0073 , A61B5/0031 , A61B5/076 , A61B5/1116 , A61B5/4504 , A61B5/686 , A61B17/7002 , A61B2017/00221 , A61B2560/0219 , A61B2560/0223 , A61B2562/0261 , G01F15/066 , G01L1/14 , H01Q7/00
摘要： A system and apparatus for providing an in- vivo assessment of relative movement of an implant that is positioned in a living being is provided that comprises a first assembly and a second assembly that are positioned within the living being. The first assembly comprises a passive electrical resonant circuit that is configured to be selectively electromagnetically coupled to an ex-vivo source of RF energy and, in response to the electromagnetic coupling, generates an output signal characterized by a frequency that is dependent upon a distance between the first assembly and the second assembly at the time of the electromagnetic coupling.
摘要翻译：提供了一种系统和装置，用于提供定位在活体中的植入物的相对运动的体内评估，该植入物包括位于生物体内的第一组件和第二组件。第一组件包括无源电谐振电路，其被配置为选择性地电磁耦合到离体RF能量源，并且响应于电磁耦合，产生以由频率表示的频率的输出信号，该频率取决于第一组件和第二组件在电磁耦合时。

7. 发明申请

WO2007002225A2 IMPLANTABLE WIRELESS SENSOR FOR IN VIVO PRESSURE MEASUREMENT 审中-公开
标题翻译：用于体内压力测量的可植入式无线传感器
公开(公告)号：WO2007002225A2
公开(公告)日：2007-01-04
申请号：PCT/US2006/024185
申请日：2006-06-21
申请人： CARDIOMEMS, INC. , O'BRIEN, David , WHITE, Jason , FONSECA, Michael , CROS, Florent , KROH, Jason , STERN, David , ALLEN, Mark
发明人： O'BRIEN, David , WHITE, Jason , FONSECA, Michael , CROS, Florent , KROH, Jason , STERN, David , ALLEN, Mark
CPC分类号： A61B5/0031 , A61B5/0215 , A61B5/076 , A61B2560/0219 , A61B2562/028
摘要： A sensor suitable for in vivo implantation has a capacitive circuit and a three-dimensional inductor coil connected to the capacitive circuit to form an LC circuit. The LC circuit is hermetically encapsulated within an electrically insulating housing. An electrical characteristic of the LC circuit is responsive to a change in an environmental parameter.
摘要翻译：适用于体内植入的传感器具有电容电路和连接到电容电路的三维电感线圈，以形成LC电路。 LC电路气密地封装在电绝缘壳体内。 LC电路的电气特性响应于环境参数的变化。

8. 发明申请

WO2004014456A3 IMPLANTABLE WIRELESS SENSOR FOR BLOOD PRESSURE MEASUREMENT WITHIN AN ARTERY 审中-公开
公开(公告)号：WO2004014456A3
公开(公告)日：2004-02-19
申请号：PCT/US2003/024751
申请日：2003-08-07
申请人： CARDIOMEMS, INC. , ALLEN, Mark , FONSECA, Michael , WHITE, Jason , KROH, Jason , STERN, David
发明人： ALLEN, Mark , FONSECA, Michael , WHITE, Jason , KROH, Jason , STERN, David
IPC分类号： A61B5/02
摘要： Intra-arterial blood pressure is monitored by inserting a pressure transducer sensor (250) using a catheter (258) into an artery and then using a small, hand-held read out device to measure pressure easily, safely, inexpensively and accurately. In one aspect a sensor (250) is introduced into the body by the steps of folding or rolling the sensor into a cylinder, loading it into a catheter, and deploying into the artery by allowing it to unroll or unfold, either by itself or facilitated by the incorporation of a super-elastic allow component.

9. 发明申请

WO2003061504A1 IMPLANTABLE WIRELESS SENSOR 审中-公开
标题翻译：可植入无线传感器
公开(公告)号：WO2003061504A1
公开(公告)日：2003-07-31
申请号：PCT/US2003/002001
申请日：2003-01-22
申请人： CARDIOMEMS, INC. , FONSECA, Michael , ALLEN, Mark , STERN, David , WHITE, Jason , KROH, Jason
发明人： FONSECA, Michael , ALLEN, Mark , STERN, David , WHITE, Jason , KROH, Jason
IPC分类号： A61B19/00
CPC分类号： A61B5/03 , A61B5/0002
摘要： The progress of a endovascular aneurysm repair can be monitored by inserting a pressure transducer sensor (110) using a catheter (92) into the sac during endovascular aneurysm repair and then using a small, hand-held read out device to measure pressure easily, safely, inexpensively and accurately. In one aspect a sensor (110) is introduced into the body by the steps of folding or rolling the sensor (110) into a cylinder, loading it into a catheter (94), and deploying into the aneurysm sac by allowing it to unroll or unfold, either by itself or facilitated by the incorporation of a super-elastic alloy component.
摘要翻译：血管内动脉瘤修复的进展可以通过在血管内动脉瘤修复期间使用导管（92）插入到囊中来插入压力换能器传感器（110）来监测，然后使用小的手持式读出装置来容易地，安全地测量压力，廉价和准确。在一个方面，传感器（110）通过将传感器（110）折叠或滚动成圆柱体，将其装载到导管（94）中并通过允许其展开或展开而部署到动脉瘤囊中的步骤被引入体内自身展开或通过加入超弹性合金组分来促进。

10. 发明申请

WO2003061467A1 IMPLANTABLE WIRELESS SENSOR FOR PRESSURE MEASUREMENT WITHIN THE HEART 审中-公开
标题翻译：可植入的无线传感器用于心脏内的压力测量
公开(公告)号：WO2003061467A1
公开(公告)日：2003-07-31
申请号：PCT/US2003/002002
申请日：2003-01-22
申请人： CARDIOMEMS, INC. , ALLEN, Mark , FONSECA, Michael , STERN, David , WHITE, Jason , KROH, Jason
发明人： FONSECA, Michael , STERN, David , WHITE, Jason , KROH, Jason
IPC分类号： A61B5/0215
CPC分类号： A61B5/0031 , A61B5/0215
摘要： The progress of a endovascular cardiac repair can be monitored by inserting a pressure transducer sensor with a first layer (242), a second layer (248), and a third layer (252), using a catheter into a chamber of the heart during endovascular repair and then using a small, hand-held read out device to measure pressure easily, safely, inexpensively and accurately. The sensor contains conductive spiral coils (244) and (254) to form an LC circuit. In one aspect a sensor is introduced into the body by the steps of folding or rolling the sensor into a cylinder, loading it into a catheter, and deploying into the heart chamber by allowing it to unroll or unfold, either by itself or facilitated by the incorporation of a super-elastic alloy component.
摘要翻译：通过使用导管插入具有第一层（242），第二层（248）和第三层（252）的压力传感器传感器，可以监测血管内心脏修复的进展在血管内修复过程中进入心脏腔内，然后使用小型手持式读出装置轻松，安全，便宜和准确地测量压力。传感器包含导电螺旋线圈（244）和（254）以形成LC电路。在一个方面，通过将传感器折叠或滚动到圆柱体中，将其装载到导管中，并且通过允许其自身展开或展开到心脏腔室中来将传感器引入到身体中，掺入超弹性合金成分。

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