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1. 发明申请

WO2010122407A2 HYPOLIPAEMIC PHARMACEUTICAL COMPOSITIONS 审中-公开
标题翻译：高血压药物组合物
公开(公告)号：WO2010122407A2
公开(公告)日：2010-10-28
申请号：PCT/IB2010000898
申请日：2010-04-21
申请人： CADILA PHARMACUETICALS LTD , MODI INDRAVADN AMBALAL , KHAMAR BAKULESH MAFATLAL , GUPTA CHHITAR MAL , PURI ANJU , BHATTA RABI SANKAR , PRATAP RAM , JAIN GIRISH KUMAR , BHADAURIA SMRATI , KHANNA ASHOK KUMAR , ASTHANA OMKAR PRASAD , GHATAK ASHIM
发明人： MODI INDRAVADN AMBALAL , KHAMAR BAKULESH MAFATLAL , GUPTA CHHITAR MAL , PURI ANJU , BHATTA RABI SANKAR , PRATAP RAM , JAIN GIRISH KUMAR , BHADAURIA SMRATI , KHANNA ASHOK KUMAR , ASTHANA OMKAR PRASAD , GHATAK ASHIM
IPC分类号： A61K31/57 , A61K31/401
CPC分类号： A61K31/57 , A61K31/401
摘要： The present invention related to hypolipaemic pharmaceutical compositions comprising lipid lowering agents and BAR antagonist such as 3ß-hydroxy pregna-5,16-d?en-20-one (Herein known as 16 DP), Guggulsterones, 16 DP is also given a compound number 80/574.
摘要翻译：本发明涉及含有降血脂剂和BAR拮抗剂如3β-羟基孕烯-5,16-d-en-20-（本申请称为16DP），Guculsterones，16DP的降血脂药物组合物也给予化合物编号80/574。

2. 发明申请

WO2010122407A3 HYPOLIPAEMIC PHARMACEUTICAL COMPOSITIONS 审中-公开
标题翻译：高血压药物组合物
公开(公告)号：WO2010122407A3
公开(公告)日：2011-03-03
申请号：PCT/IB2010000898
申请日：2010-04-21
申请人： CADILA PHARMACUETICALS LTD , MODI INDRAVADN AMBALAL , KHAMAR BAKULESH MAFATLAL , GUPTA CHHITAR MAL , PURI ANJU , BHATTA RABI SANKAR , PRATAP RAM , JAIN GIRISH KUMAR , BHADAURIA SMRATI , KHANNA ASHOK KUMAR , ASTHANA OMKAR PRASAD , GHATAK ASHIM
发明人： MODI INDRAVADN AMBALAL , KHAMAR BAKULESH MAFATLAL , GUPTA CHHITAR MAL , PURI ANJU , BHATTA RABI SANKAR , PRATAP RAM , JAIN GIRISH KUMAR , BHADAURIA SMRATI , KHANNA ASHOK KUMAR , ASTHANA OMKAR PRASAD , GHATAK ASHIM
IPC分类号： C12N15/09 , C12N5/16
CPC分类号： A61K31/57 , A61K31/401
摘要： The present invention related to hypolipaemic pharmaceutical compositions comprising lipid lowering agents and BAR antagonist such as 3ß-hydroxy pregna-5,16-d?en-20-one (Herein known as 16 DP), Guggulsterones, 16 DP is also given a compound number 80/574.
摘要翻译：本发明涉及含有降血脂剂和BAR拮抗剂如3β-羟基孕烯-5,16-d-en-20-（本申请称为16DP），Guculsterones，16DP的降血脂药物组合物也给予化合物编号80/574。

3. 发明专利

AU2006238906B2 Vaccine adjuvants 未知
公开(公告)号：AU2006238906B2
公开(公告)日：2013-04-11
申请号：AU2006238906
申请日：2006-04-21
申请人： DESAI NIRAV , GHOSH PRASANTA KUMAR , KHAMAR BAKULESH MAFATLAL , MODI INDRAVADN AMBALAL , MODI RAJIV INDRAVADAN
发明人： KHAMAR BAKULESH MAFATLAL , GHOSH PRASANTA KUMAR , MODI INDRAVADN AMBALAL , MODI RAJIV INDRAVADAN , DESAI NIRAV
IPC分类号： C12N1/20 , A61K39/00
摘要： The invention relates. to a novel adjuvant

4. 发明申请

WO2006114680A2 VACCINE ADJUVANTS 审中-公开
公开(公告)号：WO2006114680A2
公开(公告)日：2006-11-02
申请号：PCT/IB2006000978
申请日：2006-04-21
申请人： KHAMAR BAKULESH MAFATLAL , MODI INDRAVADN AMBALAL CADILA , MODI RAJIV INDRAVADAN , GHOSH PRASANTA KUMAR , DESAI NIRAV
发明人： KHAMAR BAKULESH MAFATLAL , MODI INDRAVADN AMBALAL CADILA , MODI RAJIV INDRAVADAN , GHOSH PRASANTA KUMAR , DESAI NIRAV
IPC分类号： A61K39/00
CPC分类号： A61K39/39 , A61K2039/55594
摘要： The invention relates. to a novel adjuvant Mycobacterium w and or its constituents and adjuvant containing composition, which contains antigen (s) with pharmaceutical acceptable carrier and its uses. Mycobacterium w and or its constituents when administered with antigen (s) to mammal results in enhanced immunogenicity of antigen. The enhanced immunogenicity manifests as humoral responses as well as cell mediated immunity. The adjuvant effect is seen with variety of antigens in various mammals irrespective of their immune status at the time of administration of Mycobacterium w and antigen containing composition, e.g. immune naÊve or preimmunised status.
摘要翻译：本发明涉及涉及含有抗原与药学上可接受的载体及其用途的新型佐剂分枝杆菌及其组分和含佐剂的组合物。当向哺乳动物施用抗原时，分枝杆菌和/或其成分导致抗原的增强的免疫原性。增强的免疫原性表现为体液应答以及细胞介导的免疫。在施用分枝杆菌和含抗原的组合物时，各种哺乳动物中的各种抗原可以观察到佐剂效果，而不管其免疫状态如何。免疫原或免疫前状态。

5. 发明专利

GB2442408B Mycobacterium W as an adjuvant 未知
公开(公告)号：GB2442408B
公开(公告)日：2010-06-30
申请号：GB0801474
申请日：2006-04-21
申请人： CADILA PHARMACEUTICALS LTD , MODI INDRAVADN AMBALAL , MODI RAJIV INDRAVADAN , GHOSH PRASANTA KUMAR , DESAI NIRAV
发明人： KHAMAR BAKULESH MAFATLAL , MODI INDRAVADN AMBALAL , MODI RAJIV INDRAVADAN , GHOSH PRASANTA KUMAR , DESAI NIRAV
IPC分类号： A61K39/04 , A61K35/74 , A61K39/00 , A61K39/395 , A61P35/00 , A61P37/04
摘要： The invention relates to a novel adjuvant Mycobacterium w and or its constituents and adjuvant containing composition, which contains antigen(s) with pharmaceutical acceptable carrier and its uses. Mycobacterium w and or its constituents when administered with antigen(s) to mammal results in enhanced immunogenicity of antigen. The enhanced immunogenicity manifests as humoral responses as well as cell mediated immunity. The adjuvant effect is seen with variety of antigens in various mammals irrespective of their immune status at the time of administration of Mycobacterium w and antigen containing composition. e.g. immune naïve or preimmunized status.

6. 发明公开

EP1296682A4 CHEMOSENSITIZER 审中-公开
标题翻译：化学增敏剂
公开(公告)号：EP1296682A4
公开(公告)日：2004-11-10
申请号：EP01940915
申请日：2001-06-26
申请人： KHAMAR BAKULESH MAFATLAL
发明人： KHAMAR BAKULESH MAFATLAL
IPC分类号： A61K31/00 , A61K31/4525 , A61K31/445 , C07D211/16
CPC分类号： A61K31/4525
摘要： Chemotherapeutic agents are used to treat infections caused by bacteria, virus, protozoa, parasites, and various malignant diseases like cancer. The major problem associated with use of chemotherapeutic agents is resistance to chemoptherapeutic agents. Mechanisms underlying resistance to chemotherapeutic agents include inactivation/modification of antibiotic (beta-lactams, chloramphenicol), insensitive target site (beta-lactams, glycopeptides, macrolides, tetracyclines), decreased drug accumulation in the form of enhanced efflux (tetracyclines, chloroquine, macrolides, anticancer drugs), by-pass of antibiotic sensitive step (methicillin, sulphonamides) etc. The common mechanisms underlying drug resistance is to restrict concentration of drug at the site of action usually intracellular. This can be in the form or restricting the entry of the drug into the cell by various mechanisms including altered cell wall permeability. It can also be in the form of removing the drug from site of action e.g. intracellular so that therapeutic concentration are not achieved. The drugs restoring sensitiviy of chemotherapeutic agents are broadly known as chemosensitizers. Compounds belonging to a group of R-1-3-benzodiaxole are found to be chemosensitizer as per the present invention. Piperine is one such compound belonging to a group of R-1-3-benzodiaxole are found to be chemosensitizer as per the present invention. Piperine is one such compound belonging to R-1-3 benzodiaxole group. It is found to reverse resistance to chemotherapeutic agents like rifampicin at dose which is easiyl achievable after oral ingestion of the drug.

7. 发明专利

GB2392620B Use of Mycobacterium w in the treatment of obstructive lung disease 未知
公开(公告)号：GB2392620B
公开(公告)日：2005-02-16
申请号：GB0400092
申请日：2003-03-11
申请人： MODI RAJIV INDRAVADAN , KHAMAR BAKULESH MAFATLAL , CADILA PHARMACEUTICALS LTD
发明人： KHAMAR BAKULESH MAFATLAL , MODI RAJIV INDRAVADAN
IPC分类号： A61K47/20 , A61K35/74 , A61K39/04 , A61K39/39 , A61P11/00 , A61P11/06
摘要： The invention relates to process for the preparation of formulations comprising a microorganism Mycobacterium w for the management of bronchial Asthma (obstructive lung disease).

8. 发明专利

BR0303388A 未知
公开(公告)号：BR0303388A
公开(公告)日：2004-07-20
申请号：BR0303388
申请日：2003-03-11
申请人： RAJIV INDRAVADAN MODI , KHAMAR BAKULESH MAFATLAL
发明人： KHAMAR BAKULESH MAFATLAL
IPC分类号： A61K47/20 , A61K35/74 , A61K39/04 , A61K39/39 , A61P11/00 , A61P11/06 , C12N9/48 , C12N1/20
摘要： The invention relates to process for the preparation of formulations comprising a microorganism Mycobacterium w for the management of bronchial Asthma (obstructive lung disease).

9. 发明专利

AU2003208505A1 PROCESS FOR PREPARATION OF PHARMACEUTICAL COMPOSITION 未知
公开(公告)号：AU2003208505A1
公开(公告)日：2003-09-29
申请号：AU2003208505
申请日：2003-03-06
申请人： MODI RAJIV INDRAVADAN , DAVE BRIJESH , RAMANI CHANDIR CHIMANDAS , NAIK PRAFUL , KHAMAR BAKULESH MAFATLAL
发明人： KHAMAR BAKULESH MAFATLAL
IPC分类号： A61K35/74 , A61P31/06
摘要： The invention relates to the method of treating tuberculosis comprises use of a microorganism Mycobacterium w for the treatment of tuberculosis.

10. 发明专利

AU2003209544A8 Use of mycobacterium w in the treatment of asthama(obstructive lung disease) 未知
公开(公告)号：AU2003209544A8
公开(公告)日：2003-09-22
申请号：AU2003209544
申请日：2003-03-11
申请人： KHAMAR BAKULESH MAFATLAL , MODI RAJIV INDRAVADAN
发明人： KHAMAR BAKULESH MAFATLAL
IPC分类号： A61K35/74 , A61K39/00 , A61K39/04 , A61P11/06

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