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1. 发明授权

US5968802A Nuclear cyclophilin 失效
标题翻译：核亲环素
公开(公告)号：US5968802A
公开(公告)日：1999-10-19
申请号：US482728
申请日：1995-06-07
申请人： Bruce Wang , Donald Payan , Joseph Fisher
发明人： Bruce Wang , Donald Payan , Joseph Fisher
IPC分类号： C12N1/21 , C12N9/90 , C07H21/04 , C12N15/63
CPC分类号： C12N9/90
摘要： Cyclophilin-60 proteins, nucleic acids, and monoclonal antibodies are provided.
摘要翻译：提供了Cyclophilin-60蛋白，核酸和单克隆抗体。

2. 发明授权

US08330477B1 Test engine for integrated circuit chip testing 有权
标题翻译：用于集成电路芯片测试的测试引擎
公开(公告)号：US08330477B1
公开(公告)日：2012-12-11
申请号：US12352439
申请日：2009-01-12
申请人： Albert Wu , Chiping Ai , Hungchi Chen , Bruce Wang , Abdul Elaydi
发明人： Albert Wu , Chiping Ai , Hungchi Chen , Bruce Wang , Abdul Elaydi
IPC分类号： G01R31/00 , G01R31/20
CPC分类号： G01R31/2601 , G01R31/318371 , G01R31/31919 , G06F15/00 , H01L23/544 , H01L2924/0002 , H01L2924/00
摘要： Some of the embodiments of the present disclosure provide an integrated circuit (IC) chip comprising a die, a system on chip (SOC) coupled to the die, and an internal test engine included in the SOC and configured to test the die, wherein one or more components within the IC chip may be configured to be tested by an external test engine coupled to the IC chip. Other embodiments are also described and claimed.
摘要翻译：本公开的一些实施例提供了一种集成电路（IC）芯片，其包括芯片，耦合到管芯的芯片上系统（SOC）和包括在SOC中并被配置为测试裸片的内部测试引擎，其中一个 IC芯片内的多个组件可以被配置为通过耦合到IC芯片的外部测试引擎进行测试。还描述和要求保护其他实施例。

3. 发明授权

US08071324B2 Methods for diagnosing and treating kidney cancer 有权
标题翻译：肾癌诊断和治疗方法
公开(公告)号：US08071324B2
公开(公告)日：2011-12-06
申请号：US12326632
申请日：2008-12-02
申请人： Bruce Wang , Matthias Wabl
发明人： Bruce Wang , Matthias Wabl
IPC分类号： G01N33/574
CPC分类号： G01N33/57438 , C07K16/28 , C07K16/3038 , C12Q1/6886 , C12Q2600/106 , C12Q2600/156
摘要： Methods, reagents and kits for diagnosing and treating kidney cancer are disclosed. An immunoassay for detecting kidney cancer is based on the relative change of the CELSR1 protein in urine or blood compared with normal tissue. An immunohistochemical assay for detecting kidney cancer is based on the relative absence of labeled antibody binding to cancerous tissue, compared with normal tissue.
摘要翻译：公开了用于诊断和治疗肾癌的方法，试剂和试剂盒。用于检测肾癌的免疫测定是基于尿液或血液中CELSR1蛋白与正常组织相比的相对变化。与正常组织相比，用于检测肾癌的免疫组织化学测定是基于与癌组织结合的标记抗体相对不存在的。

4. 发明授权

US07488584B2 Methods for diagnosing and treating kidney and colorectal cancer 失效
标题翻译：诊断和治疗肾脏和结肠直肠癌的方法
公开(公告)号：US07488584B2
公开(公告)日：2009-02-10
申请号：US11388550
申请日：2006-03-24
申请人： Bruce Wang , Matthias Wabl
发明人： Bruce Wang , Matthias Wabl
IPC分类号： G01N33/574
CPC分类号： G01N33/57419 , G01N33/5082 , G01N33/57438 , G01N33/57492
摘要： Methods, reagents and kits for diagnosing and treating cancer such as kidney or colorectal cancer are disclosed. An immunoassay for detecting kidney or colorectal cancer is based on the relative change of the ADAMTSL4 protein in urine or blood compared with normal tissue. An immunohistochemical assay for detecting kidney or colorectal cancer is based on the relative absence of labeled antibody binding to cancerous tissue, compared with normal tissue.
摘要翻译：公开了用于诊断和治疗诸如肾或结肠直肠癌的癌症的方法，试剂和试剂盒。用于检测肾或结肠直肠癌的免疫测定是基于与正常组织相比，尿液或血液中ADAMTSL4蛋白质的相对变化。用于检测肾或结肠直肠癌的免疫组织化学测定是基于与正常组织相比，与癌组织结合的标记抗体的相对不存在。

5. 发明授权

US06108199A Modular portable personal computer having bays to receive interchangeable modules 失效
标题翻译：具有用于接收可互换模块的托架的模块化便携式个人计算机
公开(公告)号：US06108199A
公开(公告)日：2000-08-22
申请号：US958721
申请日：1997-10-23
申请人： Timothy A. Bonardi , Eric D. Fuhs , Peter A. Ojeda , Wayne L. Griffin , William C. Hallowell , John P. Wagner , Bruce Wang , Elisa E. Zappacosta
发明人： Timothy A. Bonardi , Eric D. Fuhs , Peter A. Ojeda , Wayne L. Griffin , William C. Hallowell , John P. Wagner , Bruce Wang , Elisa E. Zappacosta
IPC分类号： G06F1/16 , G06F1/18 , G06F1/20 , H05K7/10
CPC分类号： G06F1/184 , G06F1/1601 , G06F1/1616 , G06F1/1632 , G06F1/1635 , G06F1/1654 , G06F1/1656 , G06F1/1658 , G06F1/1681 , G06F1/181 , G06F1/187 , G06F1/203 , G06F2200/1612
摘要： A modular portable personal computer includes one or more flexible bays accessible from the front surface of the computer. One or more of the flexible bays may be configured as a dual functional bay to enable the bay to interchangeably receive different modular devices, such as a modular floppy disk drive or a modular battery pack. With such a configuration, the modular floppy disk drive can be removed for portable operation and an additional battery pack installed to provide increased electrical power to the portable personal computer during portable operation. The portable personal computer is also provided with a plurality of cavities formed in a bottom surface. These cavities allow for various upgrades to be made without opening the computer housing. For example, a modular hard disk drive cavity is provided on the bottom side of the personal computer. The modular hard disk drive cavity is adapted to receive a modular hard disk drive which can be relatively easily removed and installed without opening the computer housing. In addition, a cavity may be provided which is closed by an access cover which includes one or more standard in-line memory module (SIMM) sockets to enable additional SIMMS to be added without opening the computer housing. The CPU in the modular portable personal computer can also be rather easily and quickly replaced. In particular, a cavity is formed in the bottom of the portable personal computer and carries an electrical connector that is electrically connected to the mother board. A CPU mounted on a printed circuit board (PCB) is adapted to be received in the cavity. A mating connector is provided on the PCB to enable the CPU to be connected to the motherboard. An access panel provides access to the cavity to enable the CPU to be replaced without the need to open the computer housing.
摘要翻译：模块化便携式个人计算机包括可从计算机的前表面接近的一个或多个柔性托架。一个或多个柔性隔架可以被配置为双功能托架，以使托架可互换地接收不同的模块化设备，例如模块化软盘驱动器或模块化电池组。通过这样的配置，可以移除模块化软盘驱动器以进行便携式操作，并且安装附加的电池组，以在便携式操作期间向便携式个人计算机提供增加的电力。便携式个人计算机还设置有形成在底面中的多个空腔。这些空腔允许在不打开计算机外壳的情况下进行各种升级。例如，在个人计算机的底侧设置有模块化的硬盘驱动器腔。模块化硬盘驱动器腔适于接收可相对容易地移除和安装而不打开计算机外壳的模块化硬盘驱动器。此外，可以提供一个空腔，其由包括一个或多个标准的在线存储器模块（SIMM）插座的接入盖封闭，以使得能够添加附加的SIMMS而不打开计算机外壳。模块化便携式个人计算机中的CPU也可以相当容易和快速地更换。特别地，在便携式个人计算机的底部形成空腔并且承载电连接到母板的电连接器。安装在印刷电路板（PCB）上的CPU适于容纳在空腔中。在PCB上提供一个配对连接器，以使CPU能够连接到主板上。访问面板提供对腔的访问以使得CPU能够被更换，而不需要打开计算机外壳。

6. 发明授权

US5932451A Method for unbiased mRNA amplification 失效
标题翻译：无偏差mRNA扩增方法
公开(公告)号：US5932451A
公开(公告)日：1999-08-03
申请号：US974273
申请日：1997-11-19
申请人： Bruce Wang , Alicia Chung
发明人： Bruce Wang , Alicia Chung
IPC分类号： C12N15/09 , C12Q1/68 , C12P19/34
CPC分类号： C12Q1/6844 , C12N15/1096
摘要： Methods of enzymatically producing unbiased amounts of nucleic acid from mRNA are provided. In the subject methods, a sample of mRNA is converted to ds cDNA using a primer containing an RNA polymerase site and at least one priming site. The resultant ds cDNA is then asymmetrically amplified with captureable primer to produce captureable cDNA which is then converted to captured ds cDNA. The resultant ds cDNA may then be used in a number of different applications, such as in the preparation of amplified amounts of aRNA, in the preparation of cDNA probes, and the like.
摘要翻译：提供了从mRNA中提取无偏量的核酸的方法。在本方法中，使用含有RNA聚合酶位点和至少一个引物位点的引物将mRNA样品转化为ds cDNA。然后将所得的ds cDNA用可捕获的引物不对称扩增以产生可捕获的cDNA，然后将其转化为捕获的ds cDNA。然后可以在许多不同的应用中使用所得的ds cDNA，例如制备扩增量的aRNA，在cDNA探针的制备中等。

7. 发明申请

US20100041126A1 METHODS FOR DIAGNOSING AND TREATING PROSTATE CANCER 审中-公开
标题翻译：用于诊断和治疗前列腺癌的方法
公开(公告)号：US20100041126A1
公开(公告)日：2010-02-18
申请号：US12541824
申请日：2009-08-14
申请人： Bruce Wang , Matthias Wabl
发明人： Bruce Wang , Matthias Wabl
IPC分类号： C12M1/34
CPC分类号： G01N33/57434
摘要： Devices and methods for diagnosing and treating prostate cancer are disclosed. In practicing the method, a subject's body-fluid sample is assayed for GPC3 protein, and the GPC3 level observed is used in determining whether the subject has an elevated GPC3 level associated with prostate cancer. Patients with such elevated levels may be treated, in accordance with the present disclosure, with a variety of GPC3-related immunotherapy agents.
摘要翻译：公开了用于诊断和治疗前列腺癌的装置和方法。在实施该方法时，测定受试者体液样品的GPC3蛋白，并且观察到的GPC3水平用于确定受试者是否具有与前列腺癌相关的升高的GPC3水平。根据本公开，可以使用各种GPC3相关的免疫治疗剂来治疗具有这种升高水平的患者。

8. 发明授权

US07063079B2 Device for reducing the part count and package size of an in-cylinder ionization detection system by integrating the ionization detection circuit and ignition coil driver into a single package 有权
标题翻译：用于通过将电离检测电路和点火线圈驱动器集成到单个封装中来减少缸内电离检测系统的部件数量和封装尺寸的装置
公开(公告)号：US07063079B2
公开(公告)日：2006-06-20
申请号：US10458492
申请日：2003-06-11
申请人： Garlan J. Huberts , Michael T. Nation , Guoming G. Zhu , Kevin D. Moran , Bruce Wang , Kenneth L. Gould
发明人： Garlan J. Huberts , Michael T. Nation , Guoming G. Zhu , Kevin D. Moran , Bruce Wang , Kenneth L. Gould
IPC分类号： G01C23/22
CPC分类号： F02P17/12 , F01N2430/00 , F02D41/22 , F02D2041/285 , F02M26/01 , F02P3/045 , F02P3/0453 , F02P3/051 , F02P5/1506 , F02P5/1514 , F02P5/1523 , F02P5/1526 , F02P17/02 , F02P17/10 , F02P2017/125 , F02P2017/128 , Y02T10/46
摘要： Two embodiments of an integrated ionization detection circuit and ignition coil driver, an ASIC and a single electronic package, are disclosed. The apparatuses reduce the cost and complexity of an in-cylinder ionization detection system by combining like functionality into one ASIC or electronic module easing packaging constraints. In both embodiments, a current sink is used. The current sink removes noise in the form of voltage splices. The voltage spikes are high voltage, but of short duration. The current sink prevents these spikes from turning on the IGBT. However, the current sink allows the IGBT command signal to pass. This device also comprises a switch whereby ionization current and coil primary current are multiplexed.
摘要翻译：公开了集成电离检测电路和点火线圈驱动器，ASIC和单个电子封装的两个实施例。这些装置通过将类似的功能组合成一个ASIC或电子模块来降低包装限制，降低了汽缸内电离检测系统的成本和复杂性。在两个实施例中，使用电流吸收器。电流接收器以电压接头的形式去除噪声。电压尖峰是高电压，但持续时间短。电流吸收器防止这些尖峰引起IGBT。然而，电流吸收器允许IGBT命令信号通过。该装置还包括开关，其中电离电流和线圈初级电流被复用。

9. 发明授权

US5786984A Modular portable personal computer 失效
标题翻译：模块化便携式个人电脑
公开(公告)号：US5786984A
公开(公告)日：1998-07-28
申请号：US415229
申请日：1995-03-24
申请人： Timothy A. Bonardi , Eric D. Fuhs , Peter A. Ojeda , Wayne L. Griffin , William C. Hallowell , John P. Wagner , Bruce Wang , Elisa E. Zappacosta
发明人： Timothy A. Bonardi , Eric D. Fuhs , Peter A. Ojeda , Wayne L. Griffin , William C. Hallowell , John P. Wagner , Bruce Wang , Elisa E. Zappacosta
IPC分类号： G06F1/16 , G06F1/18 , G06F1/20 , H05K7/10
CPC分类号： G06F1/1601 , G06F1/1616 , G06F1/1632 , G06F1/1635 , G06F1/1654 , G06F1/1656 , G06F1/1658 , G06F1/1681 , G06F1/181 , G06F1/184 , G06F1/187 , G06F1/203 , G06F2200/1612
摘要： A modular portable personal computer includes one or more flexible bays accessible from the front surface of the computer. One or more of the flexible bays may be configured as a dual functional bay to enable the bay to interchangeably receive different modular devices, such as a modular floppy disk drive or a modular battery pack. With such a configuration, the modular floppy disk drive can be removed for portable operation and an additional battery pack installed to provide increased electrical power to the portable personal computer during portable operation. The portable personal computer is also provided with a plurality of cavities formed in a bottom surface. These cavities allow for various upgrades to be made without opening the computer housing. For example, a modular hard disk drive cavity is provided on the bottom side of the personal computer. The modular hard disk drive cavity is adapted to receive a modular hard disk drive which can be relatively easily removed and installed without opening the computer housing. In addition, a cavity may be provided which is closed by an access cover which includes one or more standard in-line memory module (SIMM) sockets to enable additional SIMMs to be added without opening the computer housing. The CPU in the modular portable personal computer can also be rather easily and quickly replaced. In particular, a cavity is formed in the bottom of the portable personal computer and carries an electrical connector that is electrically connected to the mother board. A CPU mounted on a printed circuit board (PCB) is adapted to be received in the cavity. A mating connector is provided on the PCB to enable the CPU to be connected to the motherboard. An access panel provides access to the cavity to enable the CPU to be replaced without the need to open the computer housing.
摘要翻译：模块化便携式个人计算机包括可从计算机的前表面接近的一个或多个柔性托架。一个或多个柔性隔架可以被配置为双功能托架，以使托架可互换地接收不同的模块化设备，例如模块化软盘驱动器或模块化电池组。通过这样的配置，可以移除模块化软盘驱动器以进行便携式操作，并且安装附加的电池组，以在便携式操作期间向便携式个人计算机提供增加的电力。便携式个人计算机还设置有形成在底面中的多个空腔。这些空腔允许在不打开计算机外壳的情况下进行各种升级。例如，在个人计算机的底侧设置有模块化的硬盘驱动器腔。模块化硬盘驱动器腔适于接收可相对容易地移除和安装而不打开计算机外壳的模块化硬盘驱动器。此外，可以设置一个空腔，该空腔由包括一个或多个标准的在线存储器模块（SIMM）插座的接入盖封闭，以允许在不打开计算机外壳的情况下添加附加的SIMM。模块化便携式个人计算机中的CPU也可以相当容易和快速地更换。特别地，在便携式个人计算机的底部形成空腔并且承载电连接到母板的电连接器。安装在印刷电路板（PCB）上的CPU适于容纳在空腔中。在PCB上提供一个配对连接器，以使CPU能够连接到主板上。访问面板提供对腔的访问以使得CPU能够被更换，而不需要打开计算机外壳。

10. 发明申请

US20120180847A1 METHOD FOR IMPROVING SOLAR ENERGY CONDENSATION EFFICIENCY IN SOLAR ENERGY CONDENSATION ELECTRIC POWER FACILITY 审中-公开
标题翻译：在太阳能冷凝电力设施中提高太阳能能量冷凝效率的方法
公开(公告)号：US20120180847A1
公开(公告)日：2012-07-19
申请号：US13498914
申请日：2010-04-29
申请人： Bruce Wang
发明人： Bruce Wang
IPC分类号： H01L31/052
CPC分类号： H01L31/0543 , H01L31/0547 , Y02E10/52
摘要： A method for improving the solar energy condensation efficiency in the solar energy condensation electric power facility is provided. A corresponding twice condensing prism (11) is provided under a condensing lens. A corresponding solar cell is provided under the twice condensing prism. Reflective mirrors (21) are provided around the twice condensing prism. The twice condensing prism is provided in the reflective mirrors. The central axis of the twice condensing prism and the reflective mirrors are coincided. The distance between the normal line of the plane of the light incidence of the twice condensing prism and the reflective mirrors is greater than the distance between the normal line of the plane of the light emergence of the twice condensing prism and the reflective mirrors. The method can uniform the solar energy condensation, and improve the tolerance of the twice optical system.
摘要翻译：提供了一种用于提高太阳能冷凝电力设施中的太阳能冷凝效率的方法。在聚光透镜之下设置相应的两个聚光棱镜（11）。相应的太阳能电池设置在两个聚光棱镜的下方。反射镜（21）设置在两个聚光棱镜周围。两个聚光棱镜设置在反射镜中。两个聚光棱镜和反射镜的中心轴重合。两个聚光棱镜的光入射平面的法线与反射镜之间的距离大于两个聚光棱镜和反射镜的光出射平面的法线之间的距离。该方法可以使太阳能冷凝均匀，提高两倍光学系统的公差。

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