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1. 发明申请

US20140303719A1 PERCUTANEOUSLY IMPLANTABLE ARTIFICIAL HEART VALVE SYSTEM AND ASSOCIATED METHODS AND DEVICES 审中-公开
标题翻译： PERCUTANEOUSLY可植入人造心脏瓣膜系统及相关方法和装置
公开(公告)号：US20140303719A1
公开(公告)日：2014-10-09
申请号：US14232238
申请日：2012-06-22
申请人： Brian J. Cox , Robert Rosenbluth , Paul Lubock
发明人： Brian J. Cox , Robert Rosenbluth , Paul Lubock
IPC分类号： A61F2/24
CPC分类号： A61F2/2445 , A61F2/2418 , A61F2/2427 , A61F2/2466 , A61F2220/0008 , A61F2220/0016 , A61F2230/0065 , A61F2250/006
摘要： Expandable prosthetic valve devices for repair or replacement of a native valve in a heart of a patient and associated, systems and methods are disclosed herein. An expandable prosthetic valve device configured in accordance with a particular embodiment of the present technology can include a radially-expandable support having an expandable outer wall and a lumen defined by the outer wall. The device can also include a valve in the lumen and coupled to the support and a self-expanding retainer coupled to the outer wall. The retainer can have a structural braid configured to form a first annular flange on the outer wall of the support, and an occlusive braid configured to reduce blood flow through the retainer.
摘要翻译：用于修复或更换患者心脏中的天然瓣膜的可扩展的假体瓣膜装置以及相关联的系统和方法在此公开。根据本技术的特定实施例配置的可扩张的假体瓣膜装置可以包括具有可扩张的外壁和由外壁限定的内腔的径向可扩张的支撑件。该装置还可以包括在内腔中并且联接到支撑件的阀和联接到外壁的自扩张保持器。保持器可以具有构造成在支撑体的外壁上形成第一环形凸缘的结构编织物，以及闭合编织物，其被构造成减少通过保持器的血流。

2. 发明申请

US20140343602A1 EXPANDABLE OCCLUSION DEVICE AND METHODS 审中-公开
标题翻译：可扩展的设备和方法
公开(公告)号：US20140343602A1
公开(公告)日：2014-11-20
申请号：US14239129
申请日：2012-08-17
申请人： Brian J. Cox , Paul Lubock , Richard Quick , Robert Rosenbluth
发明人： Brian J. Cox , Paul Lubock , Richard Quick , Robert Rosenbluth
IPC分类号： A61B17/00
CPC分类号： A61B17/0057 , A61B17/12113 , A61B17/12122 , A61B2017/00575 , A61B2017/00592 , A61B2017/00606 , A61B2017/00619 , A61B2017/00623 , A61B2017/00632 , A61B2017/00853 , A61B2017/00871
摘要： An occlusion device and method for occluding an undesirable passage through tissue, such as a septal defect, that provides an expandable cylinder or other structure that occludes the passage internally or by covering one or more openings to the passage. The occlusion device includes a wire lattice or mesh that expands from a contracted catheter-deliverable state to an expanded state that occludes the passage. The lattice or mesh has one or more layers, with layers that provide structural support to the device, and layers that provide a lattice braiding or pore sizes that promote further occlusion by a biological process, such as tissue ingrowth that further occludes the affected passage.
摘要翻译：一种闭塞装置和方法，用于阻塞通过诸如间隔缺损的组织的不期望的通道，其提供可在内部封闭通道或通过覆盖一个或多个开口到通道的可扩张的气缸或其他结构。闭塞装置包括从收缩的导管可输送状态扩展到闭塞通道的扩张状态的丝网或网状物。格子或网格具有一个或多个层，其中提供对该装置的结构支撑的层，以及提供格子编织或孔径的层，其通过生物过程促进进一步闭塞，例如进一步封闭受影响的通道的组织向内生长。

3. 发明申请

US20150305756A1 METHODS AND APPARATUS FOR TREATING EMBOLISM 有权
标题翻译：治疗手术的方法和装置
公开(公告)号：US20150305756A1
公开(公告)日：2015-10-29
申请号：US14646358
申请日：2013-11-20
申请人： Robert ROSENBLUTH , Brian J. COX , Paul LUBOCK , Richard QUICK
发明人： Robert F. Rosenbluth , Brian J. Cox , Paul Lubock , Richard Quick
IPC分类号： A61B17/22 , A61B17/221
CPC分类号： A61B17/320725 , A61B17/22 , A61B17/22032 , A61B17/221 , A61B17/32075 , A61B2017/00809 , A61B2017/00862 , A61B2017/00867 , A61B2017/22034 , A61B2017/22038 , A61B2017/22081 , A61B2017/22094 , A61B2017/320716 , A61B2217/005 , A61M39/04
摘要： A method and apparatus for treating a clot in the blood vessel of a patient, and particularly the treatment of a pulmonary embolism is disclosed. The treatment includes restoring flow through the clot followed by clot removal, either partially or substantially completely. The clot treatment device is expandable into the blood vessel and may contain radial extensions that assist in restoring flow as well as in removing clot material.
摘要翻译：公开了一种用于治疗患者血管中的血块，特别是治疗肺栓塞的方法和装置。治疗包括恢复血块，然后部分或基本上完全去除血块。凝块治疗装置可扩张到血管中并且可以包含有助于恢复流动以及去除凝块材料的径向延伸部。

4. 发明授权

US08652121B2 Universal medical device control console 有权
标题翻译：通用医疗器械控制台
公开(公告)号：US08652121B2
公开(公告)日：2014-02-18
申请号：US11980956
申请日：2007-10-31
申请人： Richard L. Quick , Martin V. Shabaz , James H. Dabney , Daniel Kussman , Frank R. Louw , Paul Lubock
发明人： Richard L. Quick , Martin V. Shabaz , James H. Dabney , Daniel Kussman , Frank R. Louw , Paul Lubock
IPC分类号： A61B17/00
CPC分类号： A61B10/02 , A61B5/01 , A61B5/024 , A61B10/0266 , A61B10/0283 , A61B18/14 , A61B90/06 , A61B2017/00199 , A61B2017/00225 , A61B2017/00482 , A61B2017/008 , A61B2017/00973
摘要： A control console is disclosed for controlling one or more medical devices. The control console communicates to at least one medical device, and at least one peripheral module associated with the medical device if needed. The control console has a microprocessor for processing data to direct an operation of the medical device.
摘要翻译：公开了用于控制一个或多个医疗装置的控制台。如果需要，控制台与至少一个医疗设备通信，以及与医疗设备相关联的至少一个外围模块。控制台具有用于处理数据以引导医疗设备的操作的微处理器。

5. 发明授权

US08636637B2 Methods for asymmetrical irradiation of a body cavity 有权
标题翻译：体腔不对称照射方法
公开(公告)号：US08636637B2
公开(公告)日：2014-01-28
申请号：US13571495
申请日：2012-08-10
申请人： Paul Lubock , Michael L. Jones , Frank R. Louw
发明人： Paul Lubock , Michael L. Jones , Frank R. Louw
IPC分类号： A61N5/00
CPC分类号： A61N5/1014 , A61N5/1002 , A61N5/1015 , A61N2005/1003 , A61N2005/1004 , A61N2005/1005 , A61N2005/1018 , A61N2005/1024
摘要： The disclosure describes devices and methods for asymmetrical irradiation at a body cavity or site, such as after removal of tissue, e.g. biopsy or cancer. One device includes a lumen which is off-set or off-settable from a longitudinal axis to increase the intensity of radiation received from a radiation source by a first tissue portion surrounding the body cavity and to reduce or minimize radiation received by a second tissue portion (e.g. healthy tissue) surrounding the body cavity.
摘要翻译：本公开描述了用于在体腔或部位不对称照射的装置和方法，例如在去除组织之后，例如，活检或癌症。一个装置包括从纵向轴线偏移或不可固定的内腔，以增加围绕体腔的第一组织部分从辐射源接收的辐射的强度，并且减少或最小化由第二组织部分接收的辐射（例如健康组织）。

6. 发明授权

US08626270B2 Cavity-filling biopsy site markers 有权
标题翻译：腔填充活检部位标记
公开(公告)号：US08626270B2
公开(公告)日：2014-01-07
申请号：US13495408
申请日：2012-06-13
申请人： Fred H. Burbank , Paul Lubock , Michael L. Jones
发明人： Fred H. Burbank , Paul Lubock , Michael L. Jones
IPC分类号： A61B8/00 , A61B8/14 , A61B8/08 , A61B8/12
CPC分类号： A61B8/481 , A61B6/12 , A61B8/0833 , A61B10/02 , A61B90/39 , A61B2017/00004 , A61B2090/3908 , A61B2090/392 , A61B2090/3925 , A61B2090/395 , A61B2090/3954 , A61B2090/3966 , A61B2090/3987 , A61B2090/3995 , A61K49/006 , A61K49/222 , A61M37/0069
摘要： The invention provides materials, devices and methods for marking biopsy sites for a limited time. The biopsy-marking materials are ultrasound-detectable bio-resorbable powders, with powder particles typically between about 20 microns and about 800 microns in maximum dimension, more preferably between about 300 microns and about 500 microns. The powders may be formed of polymeric materials containing cavities sized between about 10 microns and about 500 microns, and may also contain binding agents, anesthetic agents, hemostatic agents, and radiopaque markers. Devices for delivering the powders include tubes configured to contain the powders and to fit within a biopsy cannula, the powders being ejected by action of a syringe. Systems may include a tube containing powder, and a syringe containing sterile saline. The tube may be configured to fit within a biopsy cannula such as a Mammotome® or SenoCor 360™ cannula.
摘要翻译：本发明提供用于在有限时间内标记活检部位的材料，装置和方法。活检标记材料是可超声检测的生物可再吸收粉末，粉末颗粒通常在最大尺寸为约20微米至约800微米之间，更优选为约300微米至约500微米。粉末可以由含有大约10微米至约500微米的空腔的聚合材料形成，并且还可以含有粘合剂，麻醉剂，止血剂和不透射线的标记物。用于递送粉末的装置包括被配置为容纳粉末并且装配在活检插管内的管，粉末通过注射器的作用喷射。系统可以包括含有粉末的管和含有无菌盐水的注射器。管可以被配置成装配在活检插管内，例如Mammotome或SenoCor 360 TM插管。

7. 发明授权

US08622907B2 Biopsy system with integrated imaging 有权
标题翻译：活检系统具有综合成像
公开(公告)号：US08622907B2
公开(公告)日：2014-01-07
申请号：US11810425
申请日：2007-06-05
申请人： Lloyd H. Malchow , Paul Lubock , Derek Daw
发明人： Lloyd H. Malchow , Paul Lubock , Derek Daw
IPC分类号： A61B8/00
CPC分类号： A61B10/0283 , A61B8/0833 , A61B8/0841 , A61B8/4405 , A61B8/4472 , A61B2017/00199 , A61B2090/378
摘要： A biopsy system is disclosed that has a tissue removal system, an imaging system, an image display system and a common input console for these systems. The tissue removal system can have a mechanical tissue cutting blade or an electrosurgical cutting element and the tissue removal system is capable of handling both tissue cutting configurations. The imaging system is preferably an ultrasound imaging system and the image display system has a video screen for displaying diagnostic ultrasound images from an ultrasound probe. The common input console preferably has a touch screen display and a keyboard to facilitate operation of the tissue removal system, the ultrasound imaging system and the image display system from the same console.
摘要翻译：公开了一种活检系统，其具有用于这些系统的组织去除系统，成像系统，图像显示系统和公共输入控制台。组织去除系统可以具有机械组织切割刀片或电外科切割元件，并且组织去除系统能够处理组织切割构造。成像系统优选地是超声成像系统，并且图像显示系统具有用于从超声波探头显示诊断超声图像的视频屏幕。公共输入控制台优选地具有触摸屏显示器和键盘，以便于来自相同控制台的组织去除系统，超声成像系统和图像显示系统的操作。

8. 发明授权

US08447386B2 Marker or filler forming fluid 有权
标题翻译：标记或填料成型液
公开(公告)号：US08447386B2
公开(公告)日：2013-05-21
申请号：US12967639
申请日：2010-12-14
申请人： Fred H. Burbank , Michael L. Jones , Frank Louw , Paul Lubock
发明人： Fred H. Burbank , Michael L. Jones , Frank Louw , Paul Lubock
IPC分类号： A61B6/00 , A61B10/00
CPC分类号： A61B90/39 , A61B2090/3908 , A61B2090/3925 , A61B2090/3933 , A61B2090/3987 , A61K49/226
摘要： A system for at least partially filling and marking a cavity at a site within a patient's body includes a marker delivery device having a chamber configured to contain a marking substance and having a mechanism configured to expel the marking substance. A quantity of the marking substance is contained within the chamber of the marker delivery device. The marking substance is configured to at least partially fill the cavity and form therein a porous bioabsorbable body. A delivery tube is coupled in fluid communication with the chamber of the marker delivery device. The delivery tube has a distal end with a discharge port through which the marking substance is expelled. A releasable remotely detectable distal tip is coupled to the distal end of the delivery tube and is configured to be released to remain within the porous bioabsorbable body within the cavity upon the formation thereof.
摘要翻译：一种用于至少部分地填充和标记患者体内的部位的空腔的系统包括标记物输送装置，其具有被配置为容纳标记物质并具有被构造成排出标记物质的机构的室。标记物质的量被容纳在标记物输送装置的室内。标记物质构造成至少部分地填充空腔并在其中形成多孔生物可吸收体。输送管与标记物递送装置的腔室流体连通地联接。输送管具有远端，其具有排出口，排出标记物质。可释放的可远程检测的远侧末端联接到输送管的远端，并且构造成在其形成时被释放以保持在腔内的多孔生物可吸收体内。

9. 发明授权

US08292794B2 Method for maintaining access to a biopsy site 有权
标题翻译：维持进入活检部位的方法
公开(公告)号：US08292794B2
公开(公告)日：2012-10-23
申请号：US13095304
申请日：2011-04-27
申请人： Paul Lubock , Michael L. Jones
发明人： Paul Lubock , Michael L. Jones
IPC分类号： A61N5/00
CPC分类号： A61M29/02 , A61B10/0041 , A61B17/0218 , A61B90/02 , A61B2017/00557 , A61B2017/00796 , A61B2090/3908 , A61M25/10 , A61M29/00 , A61M2025/1095 , A61N5/1015
摘要： A method for maintaining access to a biopsy site within a patient, includes forming a passageway from an opening in an exterior site on the patient to a desired location for a biopsy specimen within the patient; removing a tissue specimen from the desired location thereby leaving a biopsy cavity; providing a temporary catheter having an elongate shaft, a flexible proximal shaft section, and a distal shaft section having a cavity filling member thereon; inserting the cavity filling member on the distal shaft section into the biopsy cavity; inflating the cavity filling member after inserting the cavity filling member within the biopsy cavity, but before closing the opening, using the flexible proximal shaft section; placing the flexible proximal shaft section at an intracorporeal location; and closing the opening so as to seal the passageway.
摘要翻译：一种用于维持进入患者体内的活检部位的方法，包括从病人的外部位置的开口形成通道，以在患者体内用于活检标本的期望位置; 从所需位置移除组织标本，从而留下活检腔; 提供具有细长轴，柔性近轴部分和在其上具有空腔填充构件的远端轴部分的临时导管; 将所述空腔填充构件插入所述远端轴部分到所述活检腔中; 将空腔填充构件插入到活检腔内，但是在使用柔性近端轴段关闭开口之前使空腔填充构件膨胀; 将柔性近轴部分放置在体内位置; 并关闭开口以密封通道。

10. 发明授权

US08273006B2 Tissue irradiation 有权
标题翻译：组织照射
公开(公告)号：US08273006B2
公开(公告)日：2012-09-25
申请号：US12386100
申请日：2009-04-14
申请人： Paul Lubock , Michael L. Jones
发明人： Paul Lubock , Michael L. Jones
IPC分类号： A61N5/00
CPC分类号： A61N5/1015 , A61B2017/3419 , A61N2005/1005
摘要： Devices and methods are disclosed for treatment to tissue surrounding a body cavity or other intracorporeal site, such as after removal of tissue, e.g. cancer. Such a device includes a treatment location on a distal portion of the device with one or more radiation shielding components that partially encircle a radiation source at the treatment location to control emitted radiation from the radiation source. The device minimizes radiation damage to healthy tissue surrounding the body cavity or other site while irradiating tissue not shielded by the radiation shielding components. A device embodying features of the invention can include a sealing member at a location on a shaft of the device proximal to a treatment location to seal the passageway leading to the body cavity.
摘要翻译：公开了用于治疗围绕体腔或其他体内部位的组织的装置和方法，例如在去除组织后，例如，癌症。这种装置包括在装置的远端部分上的处理位置，其中一个或多个辐射屏蔽部件在处理位置部分地环绕辐射源以控制来自辐射源的辐射。该装置最小化对体腔或其他部位周围的健康组织的辐射损伤，同时辐射未被辐射屏蔽部件屏蔽的组织。体现本发明特征的装置可包括密封构件，该密封构件位于靠近处理位置的装置的轴上的位置处，以密封通向体腔的通道。

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