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1. 发明申请

US20150305756A1 METHODS AND APPARATUS FOR TREATING EMBOLISM 有权
标题翻译：治疗手术的方法和装置
公开(公告)号：US20150305756A1
公开(公告)日：2015-10-29
申请号：US14646358
申请日：2013-11-20
申请人： Robert ROSENBLUTH , Brian J. COX , Paul LUBOCK , Richard QUICK
发明人： Robert F. Rosenbluth , Brian J. Cox , Paul Lubock , Richard Quick
IPC分类号： A61B17/22 , A61B17/221
CPC分类号： A61B17/320725 , A61B17/22 , A61B17/22032 , A61B17/221 , A61B17/32075 , A61B2017/00809 , A61B2017/00862 , A61B2017/00867 , A61B2017/22034 , A61B2017/22038 , A61B2017/22081 , A61B2017/22094 , A61B2017/320716 , A61B2217/005 , A61M39/04
摘要： A method and apparatus for treating a clot in the blood vessel of a patient, and particularly the treatment of a pulmonary embolism is disclosed. The treatment includes restoring flow through the clot followed by clot removal, either partially or substantially completely. The clot treatment device is expandable into the blood vessel and may contain radial extensions that assist in restoring flow as well as in removing clot material.
摘要翻译：公开了一种用于治疗患者血管中的血块，特别是治疗肺栓塞的方法和装置。治疗包括恢复血块，然后部分或基本上完全去除血块。凝块治疗装置可扩张到血管中并且可以包含有助于恢复流动以及去除凝块材料的径向延伸部。

2. 发明申请

US20140343602A1 EXPANDABLE OCCLUSION DEVICE AND METHODS 审中-公开
标题翻译：可扩展的设备和方法
公开(公告)号：US20140343602A1
公开(公告)日：2014-11-20
申请号：US14239129
申请日：2012-08-17
申请人： Brian J. Cox , Paul Lubock , Richard Quick , Robert Rosenbluth
发明人： Brian J. Cox , Paul Lubock , Richard Quick , Robert Rosenbluth
IPC分类号： A61B17/00
CPC分类号： A61B17/0057 , A61B17/12113 , A61B17/12122 , A61B2017/00575 , A61B2017/00592 , A61B2017/00606 , A61B2017/00619 , A61B2017/00623 , A61B2017/00632 , A61B2017/00853 , A61B2017/00871
摘要： An occlusion device and method for occluding an undesirable passage through tissue, such as a septal defect, that provides an expandable cylinder or other structure that occludes the passage internally or by covering one or more openings to the passage. The occlusion device includes a wire lattice or mesh that expands from a contracted catheter-deliverable state to an expanded state that occludes the passage. The lattice or mesh has one or more layers, with layers that provide structural support to the device, and layers that provide a lattice braiding or pore sizes that promote further occlusion by a biological process, such as tissue ingrowth that further occludes the affected passage.
摘要翻译：一种闭塞装置和方法，用于阻塞通过诸如间隔缺损的组织的不期望的通道，其提供可在内部封闭通道或通过覆盖一个或多个开口到通道的可扩张的气缸或其他结构。闭塞装置包括从收缩的导管可输送状态扩展到闭塞通道的扩张状态的丝网或网状物。格子或网格具有一个或多个层，其中提供对该装置的结构支撑的层，以及提供格子编织或孔径的层，其通过生物过程促进进一步闭塞，例如进一步封闭受影响的通道的组织向内生长。

3. 发明申请

US20110184449A1 MARKER DELIVERY DEVICE WITH OBTURATOR 审中-公开
标题翻译：带贴标机的标记装置
公开(公告)号：US20110184449A1
公开(公告)日：2011-07-28
申请号：US13079849
申请日：2011-04-05
申请人： Paul Lubock , Richard Quick
发明人： Paul Lubock , Richard Quick
IPC分类号： A61B17/34
CPC分类号： A61B17/3468 , A61B17/3498 , A61B90/39 , A61B90/40 , A61B2017/00796 , A61B2090/062 , A61B2090/3908 , A61B2090/3954 , A61B2090/3987
摘要： A marker delivery device includes an obturator having an elongated shaft, an internal lumen, a proximal end, and a substantially sealed distal end. The substantially sealed distal end is formed of a penetrable membrane. A marker delivery tube is configured to be slidably disposed within the internal lumen of the obturator. The marker delivery tube has a marker delivery lumen, a proximal end, and a distal tip. The marker delivery lumen is configured to contain one or more tissue markers. The distal tip is configured to puncture the penetrable membrane of the substantially sealed distal end of the obturator to form a passage through which the distal tip extends to facilitate delivery of the one or more tissue markers.
摘要翻译：标记输送装置包括具有细长轴，内腔，近端和基本密封的远端的闭塞器。基本密封的远端由可穿透的膜形成。标记输送管构造成可滑动地设置在闭孔器的内腔内。标记物输送管具有标记物输送腔，近端和远端。标记递送腔被配置为包含一个或多个组织标记。远侧末端构造成刺穿闭孔的基本上密封的远端的可穿透膜以形成通道，远侧末端延伸通过该通道以促进一个或多个组织标记物的递送。

4. 发明申请

US20080058675A1 Biopsy device with aperture orientation and improved tip 有权
标题翻译：具有孔径取向和改善尖端的活检装置
公开(公告)号：US20080058675A1
公开(公告)日：2008-03-06
申请号：US11981024
申请日：2007-10-31
申请人： Martin Shabaz , Richard Quick , Frank Louw , Paul Lubock , Jason Safabash
发明人： Martin Shabaz , Richard Quick , Frank Louw , Paul Lubock , Jason Safabash
IPC分类号： A61B10/02
CPC分类号： A61B10/0233 , A61B10/0275 , A61B10/0283 , A61B17/32002 , A61B17/32053 , A61B17/3417 , A61B2010/0208 , A61B2010/0225 , A61B2017/00473 , A61B2017/3405
摘要： The invention is directed to a system and device for separating and collecting a tissue specimen from a target site within a patient. The device includes a probe component which is releasably secured to the driver component. The probe component has an elongated tubular section, a penetrating distal tip and a tissue receiving aperture in the distal end of the tubular section proximal to the distal tip, and a tissue cutting member which is slidably disposed within the probe member to cut a tissue specimen drawn into the interior of the device through the aperture by applying a vacuum to the inner lumen of the tissue cutting member. The driver has drive members for operating the elements of the probe component. The tissue penetrating distal tip preferably has a triple concave curvature shape with three curved cutting edges leading to a sharp distal point.
摘要翻译：本发明涉及一种用于从患者内的目标部位分离和收集组织标本的系统和装置。该装置包括可释放地固定到驱动器部件的探针部件。探针部件具有细长的管状部分，穿透远侧末端和在远端顶端的管状部分的远端中的组织接收孔，以及组织切割构件，其可滑动地设置在探针构件内以切割组织标本通过对组织切割构件的内腔施加真空而通过孔被吸入装置的内部。驱动器具有用于操作探头部件的元件的驱动部件。组织穿透的远侧末端优选地具有三凹曲面形状，其具有三个弯曲的切割边缘，其导致尖锐的远端点。

5. 发明申请

US20080021449A1 Electrosurgical lesion location device 有权
标题翻译：电外科病变位置装置
公开(公告)号：US20080021449A1
公开(公告)日：2008-01-24
申请号：US11890329
申请日：2007-08-06
申请人： Fred Burbank , Frank Louw , Paul Lubock , Richard Quick
发明人： Fred Burbank , Frank Louw , Paul Lubock , Richard Quick
IPC分类号： A61B18/14
CPC分类号： A61B10/0266 , A61B10/02 , A61B17/00491 , A61B17/32056 , A61B17/320725 , A61B17/3417 , A61B18/14 , A61B18/1477 , A61B18/1487 , A61B18/1492 , A61B90/17 , A61B90/37 , A61B90/39 , A61B2017/3488 , A61B2018/00208 , A61B2018/00214 , A61B2018/00267 , A61B2018/00333 , A61B2018/00577 , A61B2018/00898 , A61B2018/0091 , A61B2018/00916 , A61B2018/1253 , A61B2018/126 , A61B2018/1407 , A61B2018/1425 , A61B2018/1475 , A61B2018/162 , A61B2090/3908
摘要： A device for localizing a target tissue mass in a body includes a tubular trocar portion having a distal end and a proximal end portion that is removably attachable to a handle portion. The trocar portion contains at least a first plurality of locator wires that are movable between a retracted position within the trocar and a deployed position extending radially from the trocar. The first plurality of locator wires mounted for axial movement within the trocar portion between a proximal retracted position and a deployed distal position. The second plurality of locator wires is mounted for movement between a distal retracted position and a proximal deployed position. The locator wires are electrically energized to facilitate their deployment electrosurgically.
摘要翻译：用于使身体中的目标组织块定位的装置包括管状套管针部分，其具有可拆卸地附接到手柄部分的远端和近端部分。套针针部分包含至少第一组多个定位线，其可在套管针内的缩回位置和从套管针径向延伸的展开位置之间移动。第一组多个定位线安装用于在套管针部分内在近端缩回位置和展开的远侧位置之间轴向移动。第二组多个定位线被安装用于在远端缩回位置和近端展开位置之间移动。定位器电线通电，以方便他们在电外科手术。

6. 发明申请

US20060094983A1 Methods and apparatus for securing medical instruments to desired locations in a patient's body 审中-公开
公开(公告)号：US20060094983A1
公开(公告)日：2006-05-04
申请号：US11303154
申请日：2005-12-15
申请人： Fred Burbank , Paul Lubock , Michael Jones , Richard Quick
发明人： Fred Burbank , Paul Lubock , Michael Jones , Richard Quick
IPC分类号： A61B10/00 , A61M5/178
CPC分类号： A61B10/04 , A61B10/02 , A61B10/0241 , A61B10/0266 , A61B17/00491 , A61B17/32056 , A61B17/320725 , A61B17/3417 , A61B18/12 , A61B18/14 , A61B18/1477 , A61B18/1487 , A61B18/1492 , A61B90/17 , A61B90/37 , A61B90/39 , A61B2017/320064 , A61B2017/3488 , A61B2018/00208 , A61B2018/00214 , A61B2018/00267 , A61B2018/00333 , A61B2018/00577 , A61B2018/00601 , A61B2018/00898 , A61B2018/0091 , A61B2018/00916 , A61B2018/1253 , A61B2018/126 , A61B2018/1407 , A61B2018/1425 , A61B2018/1475 , A61B2018/162 , A61B2090/3908 , A61B2090/3987 , A61B2090/3991
摘要： Devices and methods are provided for securely affixing a medical instrument to desired tissue in a patient's body, using a fixation agent. Such medical instruments may comprise localization wires or tissue acquisition instruments, such as biopsy instruments, for example. In the case of tissue acquisition instruments, the inventors have discovered significant advantages for securely affixing the distal end of the tissue acquisition instrument to a particular tissue target area. For example, such an approach permits the imaging environment to be uncoupled from the procedural environment so that expensive and often unavailable imaging equipment, such as stereotactic imaging equipment, need not be used. In a preferred embodiment, a bonding agent, such as adhesive, surgical glue, or a solvent, is used as the fixation agent.

7. 发明申请

US20050063908A1 Tissue site markers for in vivo imaging 有权
标题翻译：用于体内成像的组织位点标记
公开(公告)号：US20050063908A1
公开(公告)日：2005-03-24
申请号：US10658911
申请日：2003-09-10
申请人： Fred Burbank , Paul Lubock , Michael Jones , Richard Quick , Frank Louw , Stephen De Santis
发明人： Fred Burbank , Paul Lubock , Michael Jones , Richard Quick , Frank Louw , Stephen De Santis
IPC分类号： A61B6/00 , A61B6/12 , A61B8/08 , A61B10/00 , A61B10/02 , A61B17/00 , A61B19/00 , A61K49/00 , A61K49/04 , A61K49/22
CPC分类号： A61M37/0069 , A61B6/12 , A61B8/0833 , A61B10/02 , A61B90/39 , A61B2017/00004 , A61B2090/08021 , A61B2090/3908 , A61B2090/3925 , A61B2090/3987 , A61K49/006 , A61K49/222
摘要： The invention is directed biopsy site markers and methods of marking a biopsy site, so that the location of the biopsy cavity is readily visible by conventional imaging methods, particularly by ultrasonic imaging. The biopsy site markers of the invention have high ultrasound reflectivity, presenting a substantial acoustic signature from a small marker, so as to avoid obscuring diagnostic tissue features in subsequent imaging studies, and can be readily distinguished from biological features. The several disclosed embodiments of the biopsy site marker of the invention have a high contrast of acoustic impedance as placed in a tissue site, so as to efficiently reflect and scatter ultrasonic energy, and preferably include gas-filled internal pores. The markers may have a non-uniform surface contour to enhance the acoustic signature. The markers have a characteristic form which is recognizably artificial during medical imaging. The biopsy site marker may be accurately fixed to the biopsy site so as to resist migration from the biopsy cavity when a placement instrument is withdrawn, and when the marked tissue is subsequently moved or manipulated.
摘要翻译：本发明涉及活检部位标记和标记活组织检查部位的方法，使得活检腔的位置通过常规成像方法，特别是通过超声成像容易看到。本发明的活检部位标记物具有高的超声反射率，从小标记物呈现出实质的声学特征，以避免在随后的成像研究中掩盖诊断组织特征，并且可以容易地与生物特征区别开来。本发明的活检部位标记物的几个公开的实施方案具有放置在组织部位中的声阻抗的高对比度，以便有效地反射和散射超声能量，并且优选地包括气体填充的内部孔。标记可以具有不均匀的表面轮廓以增强声学特征。标记具有在医学成像期间可识别人造的特征形式。可以将活检部位标记物精确地固定到活检部位，以便当放置放置器械被取出时以及随后移动或操纵标记的组织时抵抗活组织腔的迁移。

8. 发明授权

US07945307B2 Marker delivery system with obturator 有权
标题翻译：带填塞器的标记输送系统
公开(公告)号：US07945307B2
公开(公告)日：2011-05-17
申请号：US11499466
申请日：2006-08-04
申请人： Paul Lubock , Richard Quick
发明人： Paul Lubock , Richard Quick
IPC分类号： A61B5/05
CPC分类号： A61B17/3468 , A61B17/3498 , A61B90/39 , A61B90/40 , A61B2017/00796 , A61B2090/062 , A61B2090/3908 , A61B2090/3954 , A61B2090/3987
摘要： A marker delivery device is described which has an obturator with an elongated shaft, an inner lumen, a proximal end, and a substantially sealed distal end. One or more tissue markers are deployed within the inner lumen of the elongated shaft of the obturator. Preferably, the tissue marker(s) is disposed within an inner lumen of a marker delivery tube which is disposed within the inner lumen of the elongated shaft of the obturator. The marker delivery tube has an opening for discharging the tissue markers into a body (e.g. biopsy) cavity. The distal tip of the marker delivery tube is configured to penetrate the substantially sealed distal end of the obturator so that tissue markers can be delivered while the obturator is in place within the body. Preferably, the obturator includes a detectable element capable of producing a relatively significant image signature during MRI.
摘要翻译：描述了一种标记输送装置，其具有带有细长轴，内腔，近端和基本密封的远端的闭塞器。一个或多个组织标记部署在闭塞器的细长轴的内腔内。优选地，组织标记设置在标记输送管的内腔内，该标记物输送管设置在闭塞器的细长轴的内腔内。标记物输送管具有用于将组织标记物排放到体内（例如活检）腔的开口。标记物输送管的远侧末端构造成穿透闭塞器的基本上密封的远端，使得组织标记物可以在闭塞器在体内就位的同时被输送。优选地，闭孔器包括能够在MRI期间产生相对显着的图像特征的可检测元件。

9. 发明申请

US20050143674A1 Methods and apparatus for securing medical instruments to desired locations in a patient's body 有权
公开(公告)号：US20050143674A1
公开(公告)日：2005-06-30
申请号：US11059992
申请日：2005-02-17
申请人： Fred Burbank , Paul Lubock , Michael Jones , Richard Quick
发明人： Fred Burbank , Paul Lubock , Michael Jones , Richard Quick
IPC分类号： A61B10/02 , A61B10/00 , A61B17/00 , A61B17/22 , A61B17/32 , A61B17/34 , A61B18/12 , A61B18/14 , A61B19/00 , A61F2/82
CPC分类号： A61B10/04 , A61B10/02 , A61B10/0241 , A61B10/0266 , A61B17/00491 , A61B17/32056 , A61B17/320725 , A61B17/3417 , A61B18/12 , A61B18/14 , A61B18/1477 , A61B18/1487 , A61B18/1492 , A61B90/17 , A61B90/37 , A61B90/39 , A61B2017/320064 , A61B2017/3488 , A61B2018/00208 , A61B2018/00214 , A61B2018/00267 , A61B2018/00333 , A61B2018/00577 , A61B2018/00601 , A61B2018/00898 , A61B2018/0091 , A61B2018/00916 , A61B2018/1253 , A61B2018/126 , A61B2018/1407 , A61B2018/1425 , A61B2018/1475 , A61B2018/162 , A61B2019/5487 , A61B2019/5491 , A61B2090/3908 , A61B2090/3991
摘要： Devices and methods are provided for securely affixing a medical instrument to desired tissue in a patient's body, using a fixation agent. Such medical instruments may comprise localization wires or tissue acquisition instruments, such as biopsy instruments, for example. In the case of tissue acquisition instruments, the inventors have discovered significant advantages for securely affixing the distal end of the tissue acquisition instrument to a particular tissue target area. For example, such an approach permits the imaging environment to be uncoupled from the procedural environment so that expensive and often unavailable imaging equipment, such as stereotactic imaging equipment, need not be used. In a preferred embodiment, a bonding agent, such as adhesive, surgical glue, or a solvent, is used as the fixation agent.

10. 发明申请

US20050065453A1 Biopsy device with selectable tissue receiving aperture orientation and site illumination 有权
标题翻译：活组织检查装置，可选择组织接收孔径取向和局部照明
公开(公告)号：US20050065453A1
公开(公告)日：2005-03-24
申请号：US10911106
申请日：2004-08-03
申请人： Martin Shabaz , Richard Quick , Frank Louw , Paul Lubock , Jason Safabash
发明人： Martin Shabaz , Richard Quick , Frank Louw , Paul Lubock , Jason Safabash
IPC分类号： A61B10/00 , A61B10/02 , A61B17/00 , A61B17/32 , A61B17/34
CPC分类号： A61B10/0275 , A61B10/0266 , A61B10/0283 , A61B17/32002 , A61B17/3417 , A61B90/30 , A61B2010/0208 , A61B2010/0225 , A61B2017/00473 , A61B2017/00486 , A61B2017/3405 , A61B2090/3908 , A61B2090/3987
摘要： The invention is directed to a system and device for separating and collecting a tissue specimen from a target site within a patient. The device includes a probe component with an elongated tubular section, a penetrating distal tip and a tissue receiving aperture in the distal end of the tubular section proximal to the distal tip, and a tissue cutting member which is slidably disposed within the probe member to cut a tissue specimen drawn into the interior of the device through the aperture by applying a vacuum to the inner lumen of the tissue cutting member. The device also has a driver component to which the probe component is releasably secured. The driver has a drive member for adjusting the orientation of the tubular section and thus the aperture therein and one or more drive members for moving the tissue cutting member within the tubular section to sever a tissue specimen from tissue extending into the interior of the tubular section through the aperture. The motion imparted to the tissue cutter is at least longitudinal and preferably is also oscillation and/or rotational to effectively separate a tissue specimen from tissue extending through the aperture in the tubular section.
摘要翻译：本发明涉及一种用于从患者内的目标部位分离和收集组织标本的系统和装置。该装置包括具有细长管状部分的探针部件，穿透远侧末端和在远端顶端的管状部分的远端中的组织接收孔，以及组织切割构件，其可滑动地设置在探针构件内以切割组织样本通过向组织切割构件的内腔施加真空而通过孔被拉入装置的内部。该装置还具有驱动器部件，探针组件可释放地固定到该部件上。驱动器具有用于调节管状部分的方向并因此调节其中的孔的驱动构件和一个或多个驱动构件，用于移动管状区段内的组织切割构件以将组织样本从延伸到管状部分内部的组织切断通过光圈。赋予组织切割器的运动至少是纵向的，并且优选也是振动和/或旋转以有效地将组织样本与延伸穿过管状部分中的孔的组织分离。

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