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1. 发明申请

US20060094983A1 Methods and apparatus for securing medical instruments to desired locations in a patient's body 审中-公开
公开(公告)号：US20060094983A1
公开(公告)日：2006-05-04
申请号：US11303154
申请日：2005-12-15
申请人： Fred Burbank , Paul Lubock , Michael Jones , Richard Quick
发明人： Fred Burbank , Paul Lubock , Michael Jones , Richard Quick
IPC分类号： A61B10/00 , A61M5/178
CPC分类号： A61B10/04 , A61B10/02 , A61B10/0241 , A61B10/0266 , A61B17/00491 , A61B17/32056 , A61B17/320725 , A61B17/3417 , A61B18/12 , A61B18/14 , A61B18/1477 , A61B18/1487 , A61B18/1492 , A61B90/17 , A61B90/37 , A61B90/39 , A61B2017/320064 , A61B2017/3488 , A61B2018/00208 , A61B2018/00214 , A61B2018/00267 , A61B2018/00333 , A61B2018/00577 , A61B2018/00601 , A61B2018/00898 , A61B2018/0091 , A61B2018/00916 , A61B2018/1253 , A61B2018/126 , A61B2018/1407 , A61B2018/1425 , A61B2018/1475 , A61B2018/162 , A61B2090/3908 , A61B2090/3987 , A61B2090/3991
摘要： Devices and methods are provided for securely affixing a medical instrument to desired tissue in a patient's body, using a fixation agent. Such medical instruments may comprise localization wires or tissue acquisition instruments, such as biopsy instruments, for example. In the case of tissue acquisition instruments, the inventors have discovered significant advantages for securely affixing the distal end of the tissue acquisition instrument to a particular tissue target area. For example, such an approach permits the imaging environment to be uncoupled from the procedural environment so that expensive and often unavailable imaging equipment, such as stereotactic imaging equipment, need not be used. In a preferred embodiment, a bonding agent, such as adhesive, surgical glue, or a solvent, is used as the fixation agent.

2. 发明申请

US20050063908A1 Tissue site markers for in vivo imaging 有权
标题翻译：用于体内成像的组织位点标记
公开(公告)号：US20050063908A1
公开(公告)日：2005-03-24
申请号：US10658911
申请日：2003-09-10
申请人： Fred Burbank , Paul Lubock , Michael Jones , Richard Quick , Frank Louw , Stephen De Santis
发明人： Fred Burbank , Paul Lubock , Michael Jones , Richard Quick , Frank Louw , Stephen De Santis
IPC分类号： A61B6/00 , A61B6/12 , A61B8/08 , A61B10/00 , A61B10/02 , A61B17/00 , A61B19/00 , A61K49/00 , A61K49/04 , A61K49/22
CPC分类号： A61M37/0069 , A61B6/12 , A61B8/0833 , A61B10/02 , A61B90/39 , A61B2017/00004 , A61B2090/08021 , A61B2090/3908 , A61B2090/3925 , A61B2090/3987 , A61K49/006 , A61K49/222
摘要： The invention is directed biopsy site markers and methods of marking a biopsy site, so that the location of the biopsy cavity is readily visible by conventional imaging methods, particularly by ultrasonic imaging. The biopsy site markers of the invention have high ultrasound reflectivity, presenting a substantial acoustic signature from a small marker, so as to avoid obscuring diagnostic tissue features in subsequent imaging studies, and can be readily distinguished from biological features. The several disclosed embodiments of the biopsy site marker of the invention have a high contrast of acoustic impedance as placed in a tissue site, so as to efficiently reflect and scatter ultrasonic energy, and preferably include gas-filled internal pores. The markers may have a non-uniform surface contour to enhance the acoustic signature. The markers have a characteristic form which is recognizably artificial during medical imaging. The biopsy site marker may be accurately fixed to the biopsy site so as to resist migration from the biopsy cavity when a placement instrument is withdrawn, and when the marked tissue is subsequently moved or manipulated.
摘要翻译：本发明涉及活检部位标记和标记活组织检查部位的方法，使得活检腔的位置通过常规成像方法，特别是通过超声成像容易看到。本发明的活检部位标记物具有高的超声反射率，从小标记物呈现出实质的声学特征，以避免在随后的成像研究中掩盖诊断组织特征，并且可以容易地与生物特征区别开来。本发明的活检部位标记物的几个公开的实施方案具有放置在组织部位中的声阻抗的高对比度，以便有效地反射和散射超声能量，并且优选地包括气体填充的内部孔。标记可以具有不均匀的表面轮廓以增强声学特征。标记具有在医学成像期间可识别人造的特征形式。可以将活检部位标记物精确地固定到活检部位，以便当放置放置器械被取出时以及随后移动或操纵标记的组织时抵抗活组织腔的迁移。

3. 发明申请

US20050090762A1 Electrosurgical biopsy device and method 有权
标题翻译：电外科活检装置及方法
公开(公告)号：US20050090762A1
公开(公告)日：2005-04-28
申请号：US10650027
申请日：2003-08-27
申请人： Fred Burbank , Paul Lubock , Michael Jones , Richard Quick
发明人： Fred Burbank , Paul Lubock , Michael Jones , Richard Quick
IPC分类号： A61B10/02 , A61B1/00 , A61B10/00 , A61B17/00 , A61B17/22 , A61B17/32 , A61B17/34 , A61B18/12 , A61B18/14 , A61B19/00
CPC分类号： A61B10/0266 , A61B10/02 , A61B17/00491 , A61B17/32056 , A61B17/320725 , A61B17/3417 , A61B18/14 , A61B18/1487 , A61B18/1492 , A61B90/17 , A61B90/37 , A61B2010/0208 , A61B2017/3488 , A61B2018/00208 , A61B2018/00214 , A61B2018/00267 , A61B2018/00333 , A61B2018/00898 , A61B2018/0091 , A61B2018/00916 , A61B2018/1253 , A61B2018/126 , A61B2018/1407 , A61B2018/1475 , A61B2018/162 , A61B2090/3908
摘要： An electrosurgical biopsy device includes a stylet and a cannula movably mounted on a base. The stylet has a shaft with a head at its distal end and a stylet ablation element extending distally from the head. The stylet shaft is disposed through the cannula for axial translation therein between withdrawn and extended positions. The cannula has an opening at its distal end and a tissue cutting element adjacent the opening. Both ablation elements are activatable with energy that ablates adjacent tissue. A translation mechanism controllably moves (a) the stylet between the withdrawn and extended positions end (b) the cannula between a proximal position and a distal position relative to the base.
摘要翻译：电外科活检装置包括探针和可移动地安装在基座上的套管。探针具有在其远端具有头部的轴和从头部向远侧延伸的探针消融元件。探针轴穿过套管设置，用于在撤回位置和伸出位置之间进行轴向平移。套管在其远端具有开口，并且与开口相邻的组织切割元件。两种消融元件都可以通过消融相邻组织的能量来激活。平移机构可以可控地移动（a）在缩回位置和延伸位置之间的探针（b）插管在相对于基座的近端位置和远端位置之间移动。

4. 发明申请

US20050143674A1 Methods and apparatus for securing medical instruments to desired locations in a patient's body 有权
公开(公告)号：US20050143674A1
公开(公告)日：2005-06-30
申请号：US11059992
申请日：2005-02-17
申请人： Fred Burbank , Paul Lubock , Michael Jones , Richard Quick
发明人： Fred Burbank , Paul Lubock , Michael Jones , Richard Quick
IPC分类号： A61B10/02 , A61B10/00 , A61B17/00 , A61B17/22 , A61B17/32 , A61B17/34 , A61B18/12 , A61B18/14 , A61B19/00 , A61F2/82
CPC分类号： A61B10/04 , A61B10/02 , A61B10/0241 , A61B10/0266 , A61B17/00491 , A61B17/32056 , A61B17/320725 , A61B17/3417 , A61B18/12 , A61B18/14 , A61B18/1477 , A61B18/1487 , A61B18/1492 , A61B90/17 , A61B90/37 , A61B90/39 , A61B2017/320064 , A61B2017/3488 , A61B2018/00208 , A61B2018/00214 , A61B2018/00267 , A61B2018/00333 , A61B2018/00577 , A61B2018/00601 , A61B2018/00898 , A61B2018/0091 , A61B2018/00916 , A61B2018/1253 , A61B2018/126 , A61B2018/1407 , A61B2018/1425 , A61B2018/1475 , A61B2018/162 , A61B2019/5487 , A61B2019/5491 , A61B2090/3908 , A61B2090/3991
摘要： Devices and methods are provided for securely affixing a medical instrument to desired tissue in a patient's body, using a fixation agent. Such medical instruments may comprise localization wires or tissue acquisition instruments, such as biopsy instruments, for example. In the case of tissue acquisition instruments, the inventors have discovered significant advantages for securely affixing the distal end of the tissue acquisition instrument to a particular tissue target area. For example, such an approach permits the imaging environment to be uncoupled from the procedural environment so that expensive and often unavailable imaging equipment, such as stereotactic imaging equipment, need not be used. In a preferred embodiment, a bonding agent, such as adhesive, surgical glue, or a solvent, is used as the fixation agent.

5. 发明申请

US20080077045A1 Tissue specimen encapsulation device and method thereof 有权
标题翻译：组织标本包封装置及其方法
公开(公告)号：US20080077045A1
公开(公告)日：2008-03-27
申请号：US11811952
申请日：2007-06-12
申请人： Fred Burbank , Richard Quick , Jacob Louw , Michael Jones , Paul Lubock
发明人： Fred Burbank , Richard Quick , Jacob Louw , Michael Jones , Paul Lubock
IPC分类号： A61B10/02
CPC分类号： A61B10/0266 , A61B10/02 , A61B17/00234 , A61B17/221 , A61B17/32056 , A61B17/320725 , A61B17/3417 , A61B18/14 , A61B18/1487 , A61B18/1492 , A61B90/37 , A61B2017/00287 , A61B2017/2212 , A61B2017/320064 , A61B2018/00214 , A61B2018/00267 , A61B2018/00333 , A61B2018/00898 , A61B2018/0091 , A61B2018/00916 , A61B2018/1253 , A61B2018/126 , A61B2018/1407 , A61B2018/1475 , A61B2018/162 , A61B2090/3908
摘要： A device for encapsulating tissue specimens includes a wand assembly, a sheath, and a guide assembly. The guide assembly pulls, draws, or otherwise moves the sheath about the tissue specimen. The wand assembly is disposed proximate to the tissue specimen, typically either adjacent or through the specimen. In an aspect of the encapsulating device, the guide assembly has sheath deployment members that are disposed about the tissue specimen. The sheath, which is attached to ends of the sheath deployment members and the wand assembly, is drawn over the tissue specimen as the sheath deployment members are pushed or pulled. The guide assembly is an arm or a housing that rotates about the tissue specimen. The sheath, which is secured at one end to the guide assembly and at another end to the wand assembly, is drawn over the tissue specimen as the guide assembly rotates.
摘要翻译：用于封装组织样本的装置包括棒组件，护套和引导组件。引导组件拉动，牵引或以其他方式使护套围绕组织标本移动。棒组件靠近组织标本设置，通常是相邻的或通过样本。在封装装置的一个方面中，引导组件具有围绕组织标本设置的护套展开部件。当护套展开构件被推动或拉动时，附接到鞘展开构件和杆组件的端部的护套被拉过组织标本。引导组件是围绕组织标本旋转的臂或壳体。当引导组件旋转时，在一端固定到引导组件并且另一端固定到杆组件的护套在组织样本上被拉伸。

6. 发明申请

US20060036165A1 Tissue site markers for in vivo imaging 有权
公开(公告)号：US20060036165A1
公开(公告)日：2006-02-16
申请号：US11238201
申请日：2005-09-29
申请人： Fred Burbank , Paul Lubock , Michael Jones , Richard Quick , Frank Louw , Stephen De Santis
发明人： Fred Burbank , Paul Lubock , Michael Jones , Richard Quick , Frank Louw , Stephen De Santis
IPC分类号： A61B6/00
CPC分类号： A61M37/0069 , A61B6/12 , A61B8/0833 , A61B10/02 , A61B90/39 , A61B2017/00004 , A61B2090/08021 , A61B2090/3908 , A61B2090/3925 , A61B2090/3987 , A61K49/006 , A61K49/222
摘要： The invention is directed biopsy site markers and methods of marking a biopsy site, so that the location of the biopsy cavity is readily visible by conventional imaging methods, particularly by ultrasonic imaging. The biopsy site markers of the invention have high ultrasound reflectivity, presenting a substantial acoustic signature from a small marker, so as to avoid obscuring diagnostic tissue features in subsequent imaging studies, and can be readily distinguished from biological features. The several disclosed embodiments of the biopsy site marker of the invention have a high contrast of acoustic impedance as placed in a tissue site, so as to efficiently reflect and scatter ultrasonic energy, and preferably include gas-filled internal pores. The markers may have a non-uniform surface contour to enhance the acoustic signature. The markers have a characteristic form which is recognizably artificial during medical imaging. The biopsy site marker may be accurately fixed to the biopsy site so as to resist migration from the biopsy cavity when a placement instrument is withdrawn, and when the marked tissue is subsequently moved or manipulated.

7. 发明申请

US20050245842A1 Methods and apparatus for securing medical instruments to desired locations in a patient's body 有权
标题翻译：将医疗器械固定在患者身体所需位置的方法和装置
公开(公告)号：US20050245842A1
公开(公告)日：2005-11-03
申请号：US11179277
申请日：2005-07-11
申请人： Fred Burbank , Paul Lubock , Michael Jones , Richard Quick
发明人： Fred Burbank , Paul Lubock , Michael Jones , Richard Quick
IPC分类号： A61B10/02 , A61B10/00 , A61B17/00 , A61B17/22 , A61B17/32 , A61B17/34 , A61B18/12 , A61B18/14 , A61B19/00 , A61F2/82
CPC分类号： A61B10/04 , A61B10/02 , A61B10/0241 , A61B10/0266 , A61B17/00491 , A61B17/32056 , A61B17/320725 , A61B17/3417 , A61B18/12 , A61B18/14 , A61B18/1477 , A61B18/1487 , A61B18/1492 , A61B90/17 , A61B90/37 , A61B90/39 , A61B2017/320064 , A61B2017/3488 , A61B2018/00208 , A61B2018/00214 , A61B2018/00267 , A61B2018/00333 , A61B2018/00577 , A61B2018/00601 , A61B2018/00898 , A61B2018/0091 , A61B2018/00916 , A61B2018/1253 , A61B2018/126 , A61B2018/1407 , A61B2018/1425 , A61B2018/1475 , A61B2018/162 , A61B2019/5487 , A61B2019/5491 , A61B2090/3908 , A61B2090/3991
摘要： Devices and methods are provided for securely affixing a medical instrument to desired tissue in a patient's body, using a fixation agent. Such medical instruments may comprise localization wires or tissue acquisition instruments, such as biopsy instruments, for example. In the case of tissue acquisition instruments, the inventors have discovered significant advantages for securely affixing the distal end of the tissue acquisition instrument to a particular tissue target area. For example, such an approach permits the imaging environment to be uncoupled from the procedural environment so that expensive and often unavailable imaging equipment, such as stereotactic imaging equipment, need not be used. In a preferred embodiment, a bonding agent, such as adhesive, surgical glue, or a solvent, is used as the fixation agent.
摘要翻译：提供了设备和方法，用于使用固定剂将医疗器械牢固地固定在患者体内的期望的组织上。这样的医疗器械可以包括定位线或组织采集器械，例如活检器械。在组织采集仪器的情况下，本发明人已经发现了将组织采集仪器的远端牢固地固定到特定组织靶区域的显着优点。例如，这种方法允许成像环境与程序环境分离，从而不需要使用诸如立体定向成像设备之类的昂贵和经常不可用的成像设备。在优选的实施方案中，使用粘合剂，例如粘合剂，手术胶或溶剂作为固定剂。

8. 发明申请

US20080021449A1 Electrosurgical lesion location device 有权
标题翻译：电外科病变位置装置
公开(公告)号：US20080021449A1
公开(公告)日：2008-01-24
申请号：US11890329
申请日：2007-08-06
申请人： Fred Burbank , Frank Louw , Paul Lubock , Richard Quick
发明人： Fred Burbank , Frank Louw , Paul Lubock , Richard Quick
IPC分类号： A61B18/14
CPC分类号： A61B10/0266 , A61B10/02 , A61B17/00491 , A61B17/32056 , A61B17/320725 , A61B17/3417 , A61B18/14 , A61B18/1477 , A61B18/1487 , A61B18/1492 , A61B90/17 , A61B90/37 , A61B90/39 , A61B2017/3488 , A61B2018/00208 , A61B2018/00214 , A61B2018/00267 , A61B2018/00333 , A61B2018/00577 , A61B2018/00898 , A61B2018/0091 , A61B2018/00916 , A61B2018/1253 , A61B2018/126 , A61B2018/1407 , A61B2018/1425 , A61B2018/1475 , A61B2018/162 , A61B2090/3908
摘要： A device for localizing a target tissue mass in a body includes a tubular trocar portion having a distal end and a proximal end portion that is removably attachable to a handle portion. The trocar portion contains at least a first plurality of locator wires that are movable between a retracted position within the trocar and a deployed position extending radially from the trocar. The first plurality of locator wires mounted for axial movement within the trocar portion between a proximal retracted position and a deployed distal position. The second plurality of locator wires is mounted for movement between a distal retracted position and a proximal deployed position. The locator wires are electrically energized to facilitate their deployment electrosurgically.
摘要翻译：用于使身体中的目标组织块定位的装置包括管状套管针部分，其具有可拆卸地附接到手柄部分的远端和近端部分。套针针部分包含至少第一组多个定位线，其可在套管针内的缩回位置和从套管针径向延伸的展开位置之间移动。第一组多个定位线安装用于在套管针部分内在近端缩回位置和展开的远侧位置之间轴向移动。第二组多个定位线被安装用于在远端缩回位置和近端展开位置之间移动。定位器电线通电，以方便他们在电外科手术。

9. 发明申请

US20050197594A1 Tissue accessing and anchoring device and method 审中-公开
标题翻译：组织进入和锚定装置和方法
公开(公告)号：US20050197594A1
公开(公告)日：2005-09-08
申请号：US11112449
申请日：2005-04-21
申请人： Fred Burbank , Paul Lubock , John Wardle , Frank Louw , Richard Quick
发明人： Fred Burbank , Paul Lubock , John Wardle , Frank Louw , Richard Quick
IPC分类号： A61B10/00 , A61B10/02 , A61B17/00 , A61B17/34 , A61B18/00 , A61B18/14 , A61B19/00 , A61B6/00
CPC分类号： A61B10/0266 , A61B6/4258 , A61B10/02 , A61B17/00491 , A61B18/1477 , A61B18/148 , A61B18/1482 , A61B18/1487 , A61B18/1815 , A61B90/39 , A61B2010/0208 , A61B2017/00115 , A61B2017/00867 , A61B2017/3488 , A61B2018/00208 , A61B2018/00273 , A61B2018/00333 , A61B2018/00577 , A61B2018/00601 , A61B2018/00916 , A61B2018/00958 , A61B2018/1407 , A61B2018/1425 , A61B2018/1475 , A61B2090/378 , A61B2090/3904 , A61B2090/3908 , A61B2090/392
摘要： The invention provides systems, methods and a node accessing and anchoring device, comprising an elongated shaft, a tissue cutting member, at least one anchoring element extending from a position at or near the distal end of the shaft; and a radiation detector. The radiation detector is effective to locate and identify sentinel lymph nodes following injection of radioactive material into a primary lesion site within a patient. The tissue cutting member, which may be activated with radio frequency energy, is effective to allow access of the elongated shaft to a sentinel lymph node. The anchoring elements are effective to anchor the device to or adjacent a sentinel lymph node accessed by the device. Anchoring elements may assume radially, longitudinally, or mixed radially and longitudinally curved or coiled configurations when deployed.
摘要翻译：本发明提供系统，方法和节点访问和锚定装置，包括细长轴，组织切割构件，至少一个锚固元件，其从所述轴的远端处或附近的位置延伸; 和辐射探测器。放射线检测器在将放射性物质注入患者的原发性病变部位之后，有效地定位和识别前哨淋巴结。可以用射频能量激活的组织切割构件有效地允许细长轴进入前哨淋巴结。锚定元件有效地将装置锚定到或邻近由装置访问的前哨淋巴结。锚定元件在展开时可以呈径向，纵向或混合的径向和纵向弯曲或卷绕构型。

10. 发明授权

US07771357B2 Devices and methods for occlusion of the uterine arteries 失效
标题翻译：用于闭塞子宫动脉的装置和方法
公开(公告)号：US07771357B2
公开(公告)日：2010-08-10
申请号：US10459342
申请日：2003-06-10
申请人： Fred Burbank , Michael Jones , Paul Lubock
发明人： Fred Burbank , Michael Jones , Paul Lubock
IPC分类号： A61B8/00 , A61B5/05 , A61B17/08
CPC分类号： A61B8/12 , A61B8/06 , A61B8/0833 , A61B17/12013 , A61B17/42 , A61B18/1485
摘要： Devices and methods are disclosed for treating a uterine disorder which receive its blood supply from a uterine artery. In particular, uterine fibroids are effectively treated by occluding the uterine arteries using trans-vaginal, trans-uterine, transrectal, or retroperitoneal approaches. The devices and methods are advantageous because the inventive procedures may be performed by a patient's gynecologist in the course of treatment, avoiding the need for referrals to specialist practitioners and for more radical treatments, such as hysterectomies. The methods include both temporary and permanent occlusion of the arteries. A cannula carries an imaging device and a member which will easily penetrate tissue, the member including a device which partially or completely, and temporarily or permanently, occludes a uterine artery.
摘要翻译：公开了用于治疗从子宫动脉接受其血液供应的子宫疾病的装置和方法。特别地，子宫肌瘤通过使用经阴道，经子宫，经直肠或腹膜后方法闭塞子宫动脉来有效治疗。所述装置和方法是有利的，因为本发明的方法可以由患者的妇科医生在治疗过程中进行，避免需要转诊给专科医师，以及进行诸如子宫切除术等更激进的治疗。这些方法包括动脉的临时和永久闭塞。套管携带成像装置和容易穿透组织的构件，该构件包括部分地或完全地暂时地或永久地阻塞子宫动脉的装置。

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