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1. 发明授权

US07766826B2 Multi-level averaging scheme for acquiring hemodynamic data 有权
标题翻译：用于获取血液动力学数据的多级平均方案
公开(公告)号：US07766826B2
公开(公告)日：2010-08-03
申请号：US10723364
申请日：2003-11-26
申请人： Brian B. Lee , Tommy D. Bennett
发明人： Brian B. Lee , Tommy D. Bennett
IPC分类号： A61B5/00
CPC分类号： A61B5/0031 , A61B5/0205 , A61B5/04325 , A61B5/145 , A61B5/14532 , G06F19/00
摘要： A system and method for storing and processing physiological data in a medical recording device that allows continuous data collection and storage of such data in multiple time-resolved levels are provided. The method includes: sampling one or more physiological signals at a selected sampling rate; deriving physiological parameter values from the sampled signal; storing the parameter values as they are determined in a temporary memory buffer for a predetermined storage interval; determining a statistical aspect of the stored parameter values upon expiration of the storage interval; and writing the statistical aspect to a long-term memory buffer. A number of long-term memory buffers may be designated for storing a statistical aspect of a physiological parameter at uniquely different time resolutions. The resolution of each long-term memory buffer is determined by the storage interval defined for an associated temporary memory buffer, which stores parameter values from which statistical aspects are computed.
摘要翻译：提供一种在医疗记录装置中存储和处理生理数据的系统和方法，其允许以多个时间分辨级别连续数据收集和存储这些数据。该方法包括：以选定的采样速率对一个或多个生理信号进行采样; 从采样信号中得到生理参数值; 将其在临时存储器缓冲器中确定的参数值存储在预定的存储间隔中; 在所述存储间隔期满时确定所存储的参数值的统计方面; 并将统计方面写入长期内存缓冲区。可以指定多个长期记忆缓冲器用于以独特的不同时间分辨率存储生理参数的统计方面。每个长期存储器缓冲器的分辨率由为关联的临时存储器缓冲器定义的存储间隔确定，其存储从其计算统计方面的参数值。

2. 发明授权

US08702604B2 Detection of waveform artifact 有权
标题翻译：检测波形伪影
公开(公告)号：US08702604B2
公开(公告)日：2014-04-22
申请号：US13017307
申请日：2011-01-31
申请人： Mustafa Karamanoglu , Karen J. Kleckner , Tommy D. Bennett
发明人： Mustafa Karamanoglu , Karen J. Kleckner , Tommy D. Bennett
IPC分类号： A61B5/00 , G06F19/00
CPC分类号： G06F19/3406 , A61B5/02116 , A61B5/02125 , A61B5/7217 , A61B5/7239 , G06K9/0053 , G16H40/63
摘要： A medical device system including a physiological sensor is configured to perform a method for detecting signal artifact in a signal waveform acquired by the sensor. A signal waveform is sensed in a patient using the physiological sensor and a fiducial point associated with the sensed waveform is identified. A point value is established using the fiducial point. Signal artifact is detected in response to the established point value and an established threshold, and at least a portion of the signal waveform is rejected in response to detecting signal artifact.
摘要翻译：包括生理传感器的医疗装置系统被配置为执行用于检测由传感器获取的信号波形中的信号伪影的方法。使用生理传感器在患者中感测到信号波形，并且识别与感测波形相关联的基准点。使用基准点建立点值。响应于建立的点值和建立的阈值检测信号伪像，并且响应于检测到信号伪影而拒绝信号波形的至少一部分。

3. 发明授权

US08585604B2 Integrated patient care 有权
标题翻译：综合病人护理
公开(公告)号：US08585604B2
公开(公告)日：2013-11-19
申请号：US12915992
申请日：2010-10-29
申请人： Tommy D. Bennett , Yong Kyun Cho , Randolph M. Biallas
发明人： Tommy D. Bennett , Yong Kyun Cho , Randolph M. Biallas
IPC分类号： A61B5/02
CPC分类号： G06F19/3481 , A61B5/0022 , A61B5/021 , A61B5/0215 , A61B5/0537 , A61B5/11 , A61B5/4836 , A61B5/4878 , A61B5/743 , A61B5/7435 , A61N1/37247 , G06F19/00 , G06F19/3456 , G06Q50/22 , G16H40/63 , G16H50/20
摘要： A therapy regimen, e.g., a contingent medication prescription, may be created and automatically distributed to a patient via an integrated patient care system. A clinician may create therapy instructions by at least associating patient conditions with one or more therapy regimens, e.g., medication prescriptions. In some examples, the integrated patient care system may present historical condition data to the clinician to aid the clinician with creating and/or updating the therapy instructions specific to the patient. A therapy module of the integrated patient care system may use the therapy instructions to automatically select a therapy regimen from the therapy instructions based on a patient condition detected based on a sensed physiological parameter. The physiological parameter of the patient may be sensed by an implanted or external sensor. In some examples, the therapy regimen can be presented to the patient according to a predetermined schedule or in response to the detected condition.
摘要翻译：可以创建治疗方案，例如或有药物处方，并通过综合的患者护理系统自动分配给患者。临床医生可以通过至少将患者状况与一种或多种治疗方案（例如药物处方）相关联来产生治疗指导。在一些示例中，综合的患者护理系统可向临床医生呈现历史状态数据，以帮助临床医生创建和/或更新患者特有的治疗指导。综合患者护理系统的治疗模块可以使用治疗指令根据基于检测到的生理参数检测到的患者状况从治疗指令中自动选择治疗方案。患者的生理参数可以通过植入或外部传感器来感测。在一些实例中，治疗方案可以根据预定的时间表或响应于检测到的病症呈现给患者。

4. 发明授权

US08554315B2 Methods of identifying and/or assessing cardiac arrhythmias using an implantable medical device 有权
标题翻译：使用可植入医疗装置识别和/或评估心律失常的方法
公开(公告)号：US08554315B2
公开(公告)日：2013-10-08
申请号：US13099547
申请日：2011-05-03
申请人： Yong K. Cho , Tommy D. Bennett , Barbro M. Kjellstrom , Susan C. Vadnais
发明人： Yong K. Cho , Tommy D. Bennett , Barbro M. Kjellstrom , Susan C. Vadnais
IPC分类号： A61B5/0452
CPC分类号： A61N1/056 , A61B5/0031 , A61B5/02028 , A61B5/0215 , A61B5/024 , A61B5/02405 , A61B5/042 , A61B5/046 , A61N1/3622 , A61N1/3627 , A61N1/37 , A61N1/3925 , G06F19/00 , G06F19/3418
摘要： Apparatus using one or more modes of statistical analysis with one or more monitored parameters of a patient's heart to identify and/or assess arrhythmias. Through use of the one or more modes of statistical analysis, a medical professional can be aided during evaluation of patient data for diagnosis of the patient. At least one of the monitored parameters may include one or more values used representatively for storage intervals of a selected length. As such, for each storage interval, a value may be determined for the one monitored parameter occurring at an upper percentile and a lower percentile. In addition, a median value may be determined for the one monitored parameter for each storage interval. Over a plurality of the storage intervals, these determined values can be used in one or more modes of statistical analysis to better identify and assess the arrhythmias.
摘要翻译：一种使用一种或多种统计分析模式的患者心脏的一个或多个监测参数来识别和/或评估心律失常的装置。通过使用一种或多种统计分析模式，可以在评估用于患者诊断的患者数据时辅助医学专业人员。所监视的参数中的至少一个可以包括代表性地用于所选长度的存储间隔的一个或多个值。因此，对于每个存储间隔，可以针对在上百分位数和下百分位数处发生的一个监视参数来确定值。此外，可以针对每个存储间隔的一个被监视的参数确定中值。在多个存储间隔中，这些确定的值可以用于一种或多种统计分析模式，以更好地识别和评估心律失常。

5. 发明授权

US08372013B2 Method and apparatus for determining a respiration parameter in a medical device 有权
标题翻译：用于确定医疗装置中的呼吸参数的方法和装置
公开(公告)号：US08372013B2
公开(公告)日：2013-02-12
申请号：US12262285
申请日：2008-10-31
申请人： Maneesh Shrivastav , Yong K. Cho , Tommy D. Bennett , Mark K. Erickson , Saul E. Greenhut , Karen J. Kleckner , Charles P. Sperling
发明人： Maneesh Shrivastav , Yong K. Cho , Tommy D. Bennett , Mark K. Erickson , Saul E. Greenhut , Karen J. Kleckner , Charles P. Sperling
IPC分类号： A61B5/0205 , A61B5/08
CPC分类号： A61B5/6846 , A61B5/0031 , A61B5/0205 , A61B5/0215 , A61B5/0816 , A61B5/4818 , A61N1/36514 , A61N1/3702 , A61N1/37258
摘要： A method of determining a respiration parameter in a medical device in which pressure signals are sensed to generate corresponding sample points, and a breath detection threshold is continuously adjusted in response to the generated sample points to generate a current adjusted breath detection threshold. A current generated sample point is compared to the current adjusted breath detection threshold, and the continuous adjusting of the breath detection threshold is suspended and the breath detection threshold is equal to the most current adjusted breath detection threshold generated prior to the suspending in response to the comparing. A next sample point, generated subsequent to the suspending, is compared to the set breath detection threshold, and the respiration parameter is determined in response to the comparing of a next sample point to the set breath detection threshold.
摘要翻译：一种确定医疗装置中的呼吸参数的方法，其中感测压力信号以产生相应的采样点，并且响应于所产生的采样点连续地调整呼吸检测阈值以产生当前调节的呼吸检测阈值。将当前生成的采样点与当前调节的呼吸检测阈值进行比较，并且暂停呼吸检测阈值的连续调整，并且呼吸检测阈值等于响应于该呼吸检测阈值之前产生的最新调整的呼吸检测阈值比较。将在悬挂之后产生的下一采样点与设定的呼吸检测阈值进行比较，并且响应于下一采样点与设定的呼吸检测阈值的比较来确定呼吸参数。

6. 发明授权

US08202223B2 Method and apparatus for determining respiratory effort in a medical device 有权
标题翻译：用于确定医疗装置中的呼吸力的方法和装置
公开(公告)号：US08202223B2
公开(公告)日：2012-06-19
申请号：US12262320
申请日：2008-10-31
申请人： Yong K. Cho , Tommy D. Bennett , Mark K. Erickson , Maneesh Shrivastav , Saul E. Greenhut , Karen J. Kleckner , Charles P. Sperling , Robert A. Corey
发明人： Yong K. Cho , Tommy D. Bennett , Mark K. Erickson , Maneesh Shrivastav , Saul E. Greenhut , Karen J. Kleckner , Charles P. Sperling , Robert A. Corey
IPC分类号： A61B5/08 , A61B5/02
CPC分类号： A61B5/6846 , A61B5/0031 , A61B5/0205 , A61B5/0215 , A61B5/0816 , A61B5/4818 , A61N1/36514 , A61N1/3702 , A61N1/37258
摘要： A method of determining respiratory effort in a medical device in which pressure signals are sensed to generate corresponding sample points, an inspiration and an expiration are detected in response to the sensed pressure signals, a breath is detected in response to the detected inspiration and the detected expiration, and the respiratory effort is determined in response to the detected breath.
摘要翻译：一种在医疗装置中确定呼吸力的方法，其中响应于检测到的压力信号检测压力信号以产生相应的采样点，吸气和呼气，响应于检测到的吸气和检测到的呼吸被检测到呼吸到期，并且响应于检测到的呼吸来确定呼吸努力。

7. 发明授权

US08152730B2 Method for continuous baroreflex sensitivity measurement 有权
标题翻译：连续压力反射灵敏度测量方法
公开(公告)号：US08152730B2
公开(公告)日：2012-04-10
申请号：US13013465
申请日：2011-01-25
申请人： Yong K. Cho , Tommy D. Bennett
发明人： Yong K. Cho , Tommy D. Bennett
IPC分类号： A61B5/02
CPC分类号： A61B5/0205 , A61B5/0215 , A61B5/024 , A61B5/0816 , A61B5/7285 , A61N1/3627 , A61N1/36521 , A61N1/368
摘要： A medical device and method for determining baroreflex sensitivity (BRS) based on one or more respiration cycles. The BRS determination may be performed continuously based on measurements of heart rate, blood pressure, and respiration cycles.
摘要翻译：一种用于根据一个或多个呼吸周期来确定压力反射灵敏度（BRS）的医疗装置和方法。可以基于心率，血压和呼吸周期的测量来连续进行BRS测定。

8. 发明申请

US20100217135A1 METHOD AND SYSTEM FOR INTERPRETING HEMODYNAMIC DATA INCORPORATING PATIENT POSTURE INFORMATION 审中-公开
标题翻译：用于解释患有病人信息的血液动力学数据的方法和系统
公开(公告)号：US20100217135A1
公开(公告)日：2010-08-26
申请号：US12714850
申请日：2010-03-01
申请人： Yong K. Cho , Yongduk Cho , Tommy D. Bennett , Mustafa Karamanoglu
发明人： Yong K. Cho , Yongduk Cho , Tommy D. Bennett , Mustafa Karamanoglu
IPC分类号： A61B5/021 , A61B5/103
CPC分类号： A61N1/3702 , A61N1/36535 , A61N1/36542
摘要： Systems and methods for improving hemodynamic data interpretation by accounting for the effects of patient posture is disclosed. In certain embodiments, a posture signal is acquired and used to categorize hemodynamic data according to posture to facilitate distinguishing posture-related changes in acquired hemodynamic data from those due to pathophysiologic changes. Posture information may be used to normalize data acquired in various postures to facilitate interpretation of such data. Baseline measurements of hemodynamic data acquired in various postures may also be used to subsequently detect changes in patient posture without the need for an implanted posture sensor.
摘要翻译：公开了通过考虑患者姿势的影响来改善血液动力学数据解释的系统和方法。在某些实施例中，获取姿势信号并用于根据姿势对血液动力学数据进行分类，以便于将所获得的血液动力学数据中的姿势相关变化与由于病理生理变化引起的姿势相关的变化区分开。姿势信息可以用于对在各种姿势中获取的数据进行归一化，以便于解释这些数据。在各种姿势中获取的血液动力学数据的基线测量也可用于随后检测患者姿势的变化，而不需要植入的姿势传感器。

9. 发明申请

US20100076322A1 METHOD AND APPARATUS FOR DETERMINING A RESPIRATION PARAMETER IN A MEDICAL DEVICE 有权
标题翻译：用于确定医疗装置中呼吸参数的方法和装置
公开(公告)号：US20100076322A1
公开(公告)日：2010-03-25
申请号：US12262285
申请日：2008-10-31
申请人： Maneesh A. Shrivastav , Yong K. Cho , Tommy D. Bennett , Mark K. Erickson , Saul E. Greenhut , Karen J. Kleckner , Charles P. Sperling
发明人： Maneesh A. Shrivastav , Yong K. Cho , Tommy D. Bennett , Mark K. Erickson , Saul E. Greenhut , Karen J. Kleckner , Charles P. Sperling
IPC分类号： A61B5/0205 , A61B5/08
CPC分类号： A61B5/6846 , A61B5/0031 , A61B5/0205 , A61B5/0215 , A61B5/0816 , A61B5/4818 , A61N1/36514 , A61N1/3702 , A61N1/37258
摘要： A method of determining a respiration parameter in a medical device in which pressure signals are sensed to generate corresponding sample points, and a breath detection threshold is continuously adjusted in response to the generated sample points to generate a current adjusted breath detection threshold. A current generated sample point is compared to the current adjusted breath detection threshold, and the continuous adjusting of the breath detection threshold is suspended and the breath detection threshold is equal to the most current adjusted breath detection threshold generated prior to the suspending in response to the comparing. A next sample point, generated subsequent to the suspending, is compared to the set breath detection threshold, and the respiration parameter is determined in response to the comparing of a next sample point to the set breath detection threshold.
摘要翻译：一种确定医疗装置中的呼吸参数的方法，其中感测压力信号以产生相应的采样点，并且响应于所产生的采样点连续地调整呼吸检测阈值以产生当前调节的呼吸检测阈值。将当前生成的采样点与当前调节的呼吸检测阈值进行比较，并且暂停呼吸检测阈值的连续调整，并且呼吸检测阈值等于响应于该呼吸检测阈值之前产生的最新调整的呼吸检测阈值比较。将在悬挂之后产生的下一采样点与设定的呼吸检测阈值进行比较，并且响应于下一采样点与设定的呼吸检测阈值的比较来确定呼吸参数。

10. 发明授权

US5320643A Automatic cardiac capture restoration and threshold-seeking method and apparatus 失效
标题翻译：自动心脏捕获恢复和阈值寻求方法和装置
公开(公告)号：US5320643A
公开(公告)日：1994-06-14
申请号：US958194
申请日：1992-10-06
申请人： Glenn M. Roline , Lucy M. Nichols , Tommy D. Bennett , David L. Thompson
发明人： Glenn M. Roline , Lucy M. Nichols , Tommy D. Bennett , David L. Thompson
IPC分类号： A61N1/365 , A61N1/37
CPC分类号： A61N1/3712 , A61N1/36564
摘要： An automatic capture restoration and threshold-seeking method and apparatus for use with a cardiac pacemaker derives control signals for restoring cardiac capture from a cardiac pressure sensor. The pressure sensor also provides input control signals for a threshold-seeking apparatus. Both pulse width and amplitude thresholds can be changed contemporaneously during both capture restoration and threshold seeking.
摘要翻译：与心脏起搏器一起使用的自动捕获恢复和阈值寻求方法和装置导出用于从心脏压力传感器恢复心脏捕获的控制信号。压力传感器还为阈值寻求装置提供输入控制信号。在捕获恢复和阈值寻找期间，脉冲宽度和幅度阈值均可同时改变。

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