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1. 发明授权

US07884984B2 Multicolor holographic replication by masking 有权
标题翻译：通过掩蔽进行多色全息复制
公开(公告)号：US07884984B2
公开(公告)日：2011-02-08
申请号：US12080620
申请日：2008-04-04
申请人： Brett Ronald Nelson , Michael G. Fickes
发明人： Brett Ronald Nelson , Michael G. Fickes
IPC分类号： G03H1/20 , G03H1/26 , G02B5/32
CPC分类号： G03H1/202 , G03H2001/2263 , G03H2001/2271 , G03H2001/2655 , G03H2222/13 , G03H2222/18 , G03H2223/12 , Y10S359/90
摘要： A multicolor hologram (e.g., a two-color hologram) is replicated (copied) into a photosensitive layer by masking to produce a copy (replicate) of the hologram in a manner such that the copy is an accurate and true replication of the hologram (e.g., master hologram), and the copy is characterized to possess a high brightness level and color fidelity comparable to that of the multicolor hologram that was replicated. Both flood and scan modes can be employed in the replication.
摘要翻译：通过掩蔽将多色全息图（例如，双色全息图）复制（复制）到感光层中，以产生全息图的复制（复制），使得该拷贝是全息图的精确和真实的复制（例如，主全息图），并且复印件的特征在于具有与复制的多色全息图相当的高亮度水平和色彩保真度。冗余和扫描模式都可以在复制中使用。

2. 发明授权

US08045245B2 Multicolor holgraphic replication by masking 有权
标题翻译：通过掩蔽进行多色全复制
公开(公告)号：US08045245B2
公开(公告)日：2011-10-25
申请号：US13021885
申请日：2011-02-07
申请人： Brett Ronald Nelson , Michael G. Fickes
发明人： Brett Ronald Nelson , Michael G. Fickes
IPC分类号： G03H1/20 , G03H1/26 , G02B5/32
CPC分类号： G03H1/202 , G03H2001/2263 , G03H2001/2271 , G03H2001/2655 , G03H2222/13 , G03H2222/18 , G03H2223/12 , Y10S359/90
摘要： A multicolor hologram (e.g., a two-color hologram) is replicated (copied) into a photosensitive layer by masking to produce a copy (replicate) of the hologram in a manner such that the copy is an accurate and true replication of the hologram (e.g., master hologram) and the copy is characterized to possess a high brightness level and color fidelity comparable to that of the multicolor hologram that was replicated. Both flood and scan modes can be employed in the replication.
摘要翻译：通过掩蔽将多色全息图（例如，双色全息图）复制（复制）到感光层中，以产生全息图的复制（复制），使得该拷贝是全息图的精确和真实的复制（例如，主全息图），并且复印件的特征在于具有与复制的多色全息图相当的高亮度水平和色彩保真度。冗余和扫描模式都可以在复制中使用。

3. 发明申请

US20090244666A1 Multicolor holographic replication by masking 有权
标题翻译：通过掩蔽进行多色全息复制
公开(公告)号：US20090244666A1
公开(公告)日：2009-10-01
申请号：US12080620
申请日：2008-04-04
申请人： Brett Ronald Nelson , Michael G. Fickes
发明人： Brett Ronald Nelson , Michael G. Fickes
IPC分类号： G03H1/20
CPC分类号： G03H1/202 , G03H2001/2263 , G03H2001/2271 , G03H2001/2655 , G03H2222/13 , G03H2222/18 , G03H2223/12 , Y10S359/90
摘要： A method is provided for replicating (copying) a multicolor hologram (e.g., a two-color hologram) into a photosensitive layer by masking to produce a copy (replicate) of the hologram in a manner such that the copy is an accurate and true replication of the hologram (e.g., master hologram) and the copy is characterized to possess a high brightness level and color fidelity comparable to that of the multicolor hologram that was replicated.
摘要翻译：提供了一种用于通过掩蔽将多色全息图（例如双色全息图）复制（复制）到感光层中以产生全息图的复制（复制）的方式，使得该拷贝是精确和真实的复制的全息图（例如，主全息图），并且该拷贝的特征在于具有与复制的多色全息图相当的高亮度水平和色彩保真度。

4. 发明申请

US20110249307A1 HOLOGRAM AND ASSOCIATED METHODS OF FABRICATION THEREOF AND USE IN SECURITY/AUTHENTICATION APPLICATIONS 审中-公开
标题翻译： HOLOGRAM及其相关制造方法及其在安全/认证应用中的使用
公开(公告)号：US20110249307A1
公开(公告)日：2011-10-13
申请号：US12899908
申请日：2010-10-07
申请人： Brett Ronald Nelson , Michael G. Fickes
发明人： Brett Ronald Nelson , Michael G. Fickes
IPC分类号： G03H1/02 , G03F7/20
CPC分类号： G03H1/0011 , G03H1/02 , G03H1/0248 , G03H1/202 , G03H1/22 , G03H2001/0216 , G03H2001/2263 , G03H2222/10 , G03H2222/34 , G03H2223/14
摘要： A hologram (and related hologram element) contains and exhibits a holographic image when illuminated and viewed on angle and with the holographic image gradually fading when viewed increasingly off angle in 1st-3rd directions. This hologram also contains and exhibits a monochrome wash surface that obscures (partially or totally) the holographic image when viewed in a 4th direction as the hologram is increasingly rotated off angle in a 4th direction through a range of angles. The hologram can be fabricated with a variety of color choices for the monochrome wash surface. The hologram is useful in security and authentication applications and is used in a method provided herein for authentication of an article.
摘要翻译：全息图（和相关的全息元件）当照射并且在角度上观看并且全息图像（和相关的全息元件）在第1 - 3个方向上越来越远离角度时逐渐衰减，逐渐衰减。当全息图在第四方向上通过角度范围越来越多地旋转偏离角度时，该全息图还包含并表现出从第四方向观察时遮蔽（部分或全部）全息图像的单色洗涤表面。全息图可以用单色洗涤表面的各种颜色选择来制作。全息图在安全和认证应用中是有用的，并且在本文提供的用于认证物品的方法中使用。

5. 发明授权

US4452879A Preparation of ozone resistant printing plates 失效
标题翻译：防臭印版的制备
公开(公告)号：US4452879A
公开(公告)日：1984-06-05
申请号：US531992
申请日：1983-09-13
申请人： Michael G. Fickes , Peter F. Warfield
发明人： Michael G. Fickes , Peter F. Warfield
IPC分类号： G03C11/00 , G03F7/00 , G03F7/027 , G03F7/40 , G03C5/00
CPC分类号： G03F7/40 , G03F7/027
摘要： Process for improving ozone resistance of photosensitive flexographic relief printing plates prepared from at least 30% by weight of a block copolymer as defined, at least 1% by weight of at least one addition polymerizable ethylenically unsaturated compound, and a polymerization initiator wherein there is applied to the dry relief surface of said plates a solvent solution containing at least 1% by weight of a nickel or zinc dialkyldithiocarbamate compound where alkyl is from 1 to 4 carbon atoms. The treated plates which possess improved ozone resistance are useful for flexographic printing.
摘要翻译：由至少30重量％的至少1重量％的至少一种可加聚的烯键式不饱和化合物的嵌段共聚物和聚合引发剂制备的感光柔版印刷印版的耐臭氧性的方法，其中应用在所述板的干浮雕表面上，含有至少1重量％的烷基为1至4个碳原子的二烷基二硫代氨基甲酸镍或锌的溶剂溶液。具有改善的耐臭氧性的处理板可用于柔性版印刷。

6. 发明授权

US4304843A Dry toner with improved toning uniformity 失效
标题翻译：干调色剂具有改善的调色均匀性
公开(公告)号：US4304843A
公开(公告)日：1981-12-08
申请号：US091889
申请日：1979-11-07
申请人： Charles W. Manger , Michael G. Fickes , John W. Long
发明人： Charles W. Manger , Michael G. Fickes , John W. Long
IPC分类号： G03F7/28 , G03C5/24
CPC分类号： G03F7/28
摘要： Toner particles of an intimate mixture of 25 to 75% by weight of substantially colorless, inert, nonelectroscopic spheroidal-shape polymer particles of size distribution in the range of greater than 5 to less than 60 .mu.m, not more than 15% of the polymer particles being less than 10 .mu.m or greater than 50 .mu.m equivalent spherical diameter, and 75 to 25% by weight of colorant particles having a size distribution within the range of 0.2 to 30 .mu.m and not more than 50% of the colorant particles being less than 1 .mu.m particle size. Ionic copolymer spheroidal particles are preferred. The toner particles are useful for color development of tacky areas by depositing and distributing the toner particles by means of a pad, including an applicator apparatus comprising a housing for toner, a free moving weight in the housing for agitating the toner, means to release toner from the housing, and at least two hinged pads mounted on the housing.
摘要翻译： 25至75重量％的基本上无色，惰性的非电光球形聚合物颗粒的均匀混合物的调色剂颗粒，其尺寸分布在大于5至小于60μm的范围内，不超过15％的聚合物颗粒小于10微米或大于50μm的当量球形直径，和75至25重量％的着色剂颗粒，其尺寸分布在0.2至30微米范围内且不超过50％的着色剂颗粒粒径小于1μm。离子共聚物球形颗粒是优选的。调色剂颗粒可用于通过用垫沉积和分配调色剂颗粒来显色粘性区域，包括涂布装置，包括用于调色剂的壳体，用于搅拌调色剂的壳体中的自由移动重量，用于释放调色剂的装置以及至少两个安装在壳体上的铰接垫。

7. 发明授权

US5188863A Direct effect master/stamper for optical recording 失效
标题翻译：直接效应主/压模用于光学记录
公开(公告)号：US5188863A
公开(公告)日：1993-02-23
申请号：US628889
申请日：1990-12-18
申请人： Martinus J. M. de Graaf , Michael G. Fickes , George H. Johnson , Howard E. Simmons, III
发明人： Martinus J. M. de Graaf , Michael G. Fickes , George H. Johnson , Howard E. Simmons, III
IPC分类号： B29C59/02 , B29D17/00 , G11B7/26
CPC分类号： B29D17/005 , G11B7/263 , B29C59/02
摘要： A method for making optical recording media in which the optically readable information is embossed therein by means of an information master recording which is directly usable as a stamper.
摘要翻译：一种制造光学记录介质的方法，其中通过可直接用作压模的信息主记录将光学可读信息压印在其中。

8. 发明授权

US4215193A Dry toner process with improved toning uniformity for color developing an imaged tacky and nontacky surface 失效
标题翻译：干调色剂工艺具有改进的调色均匀性，用于彩色显影成像的粘性和非粘性表面
公开(公告)号：US4215193A
公开(公告)日：1980-07-29
申请号：US963083
申请日：1978-11-22
申请人： Charles W. Manger , Michael G. Fickes , John W. Long
发明人： Charles W. Manger , Michael G. Fickes , John W. Long
IPC分类号： G03G9/08 , G03F7/28 , G03G9/087 , G03G9/09 , G03G15/01 , G03C5/24
CPC分类号： G03F7/28
摘要： Toner particles of an intimate mixture of 25 to 75% by weight of substantially colorless, inert, nonelectroscopic spheroidal-shape polymer particles of size distribution in the range of greater than 5 to less than 60 .mu.m, not more than 15% of the polymer particles being less than 10 .mu.m or greater than 50 .mu.m equivalent spherical diameter, and 75 to 25% by weight of colorant particles having a size distribution within the range of 0.2 to 30 .mu.m and not more than 50% of the colorant particles being less than 1 .mu.m particle size. Ionic copolymer spheroidal particles are preferred. The toner particles are useful for color development of tacky areas by depositing and distributing the toner particles by means of a pad, including an applicator apparatus comprising a housing for toner, a free moving weight in the housing for agitating the toner, means to release toner from the housing, and at least two hinged pads mounted on the housing.
摘要翻译： 25至75重量％的基本上无色，惰性的非电光球形聚合物颗粒的均匀混合物的调色剂颗粒，其尺寸分布在大于5至小于60μm的范围内，不超过15％的聚合物颗粒小于10微米或大于50μm的当量球形直径，和75至25重量％的着色剂颗粒，其尺寸分布在0.2至30微米范围内且不超过50％的着色剂颗粒粒径小于1μm。离子共聚物球形颗粒是优选的。调色剂颗粒可用于通过用垫沉积和分配调色剂颗粒来显色粘性区域，包括涂布装置，包括用于调色剂的壳体，用于搅拌调色剂的壳体中的自由移动重量，用于释放调色剂的装置以及至少两个安装在壳体上的铰接垫。

9. 发明授权

US08399468B2 Octahydro-pyrrolo[3,4-B]pyrrole derivatives 有权
标题翻译：八氢吡咯并[3,4-B]吡咯衍生物
公开(公告)号：US08399468B2
公开(公告)日：2013-03-19
申请号：US12715660
申请日：2010-03-02
申请人： Marlon D. Cowart , Chen Zhao , Minghua Sun , Lawrence A. Black , Guo Zhu Zheng , Robert J. Gregg , Geoff G. Z. Zhang , Ahmad Y. Sheikh , Xiaochun Lou , Rodger F. Henry , David M. Barnes , Lawrence Kolaczkowski , Anthony R. Haight , Sou-Jen Chang , Steven J. Wittenberger , Michael G. Fickes
发明人： Marlon D. Cowart , Chen Zhao , Minghua Sun , Lawrence A. Black , Guo Zhu Zheng , Robert J. Gregg , Geoff G. Z. Zhang , Ahmad Y. Sheikh , Xiaochun Lou , Rodger F. Henry , David M. Barnes , Lawrence Kolaczkowski , Anthony R. Haight , Sou-Jen Chang , Steven J. Wittenberger , Michael G. Fickes
IPC分类号： A61K31/501 , C07D403/10
CPC分类号： C07D487/04
摘要： Octahydro-pyrrolo[3,4-b]pyrrole derivatives are useful in treating conditions or disorders prevented by or ameliorated by histamine-3 receptor ligands. Octahydro-pyrrolo[3,4-b]pyrrole compounds, methods for using such compounds, compositions for making them, and processes for preparing such compounds are disclosed herein.
摘要翻译：八氢吡咯并[3,4-b]吡咯衍生物可用于治疗组胺-3受体配体预防或改善的病症或病症。八氢吡咯并[3,4-b]吡咯化合物，使用这些化合物的方法，制备它们的组合物和制备这些化合物的方法在本文中公开。

10. 发明申请

US20100297194A1 FORMULATION FOR ORAL ADMINISTRATION OF APOPTOSIS PROMOTER 审中-公开
标题翻译：制剂推荐药物的口服制剂
公开(公告)号：US20100297194A1
公开(公告)日：2010-11-25
申请号：US12770299
申请日：2010-04-29
申请人： Nathaniel Catron , Michael G. Fickes , Cristina M. Fischer , Rajeev Gokhale , Anthony R. Haight , Katherine Heemstra , David Hill , Martin Knobloch , Drazen Kostelac , Justin S. Lafountaine , Yanxia Li , Bernd Liepold , Kennan Marsh , Jonathan M. Miller , Claudia Packhaeuser , Yeshwant D. Sanzgiri , Eric A. Schmitt , Yi Shi , Norbert Steiger , Ping Tong , Huailiang Wu , Geoff G.Z. Zhang , Deliang Zhou
发明人： Nathaniel Catron , Michael G. Fickes , Cristina M. Fischer , Rajeev Gokhale , Anthony R. Haight , Katherine Heemstra , David Hill , Martin Knobloch , Drazen Kostelac , Justin S. Lafountaine , Yanxia Li , Bernd Liepold , Kennan Marsh , Jonathan M. Miller , Claudia Packhaeuser , Yeshwant D. Sanzgiri , Eric A. Schmitt , Yi Shi , Norbert Steiger , Ping Tong , Huailiang Wu , Geoff G.Z. Zhang , Deliang Zhou
IPC分类号： A61K31/5377 , A61K33/04 , A61K9/14 , A61P35/00
CPC分类号： A61K31/5377 , A61K9/08 , A61K9/10 , A61K9/146 , A61K9/2054 , A61K9/2077 , A61K9/4858 , A61K9/4866
摘要： An orally deliverable pharmaceutical composition comprises as a sole or first active ingredient a compound of Formula I defined herein or a pharmaceutically acceptable salt thereof, for example ABT-263 free base or ABT-263 bis-HCl salt, dispersed, in a free base equivalent amount of at least about 2.5% by weight of the composition, in a pharmaceutically acceptable carrier; wherein said active ingredient is in solid-state form and/or the composition further comprises, dispersed in the carrier, a pharmaceutically acceptable heavier-chalcogen antioxidant in an amount effective to inhibit oxidation of the active ingredient at a thioether linkage thereof. The composition is suitable for oral administration to a subject in need thereof for treatment of a disease characterized by overexpression of one or more anti-apoptotic Bcl-2 family proteins, for example cancer.
摘要翻译：可口服递送的药物组合物包含作为唯一或第一活性成分的本文定义的式I化合物或其药学上可接受的盐，例如ABT-263游离碱或ABT-263双-HCl盐，以游离碱当量至少约2.5重量％的组合物，在药学上可接受的载体中; 其中所述活性成分是固态形式和/或所述组合物还包含以有效抑制活性成分在其硫醚键的氧化的量分散在载体中的药学上可接受的较重硫族元素抗氧化剂。该组合物适合于有需要的受试者的口服给药，用于治疗以一种或多种抗凋亡Bcl-2家族蛋白（例如癌症）过表达为特征的疾病。

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