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1. 发明授权

US5788689A Prosthetic heart valve rotator tool 失效
标题翻译：假心脏心脏旋转器工具
公开(公告)号：US5788689A
公开(公告)日：1998-08-04
申请号：US594972
申请日：1996-01-31
申请人： Bob Allan , Kimberly A. Anderson , William R. Holmberg , Kurt D. Krueger , Michael J. Girard , Thomas G. Schoon , Gary G. Rushmeyer
发明人： Bob Allan , Kimberly A. Anderson , William R. Holmberg , Kurt D. Krueger , Michael J. Girard , Thomas G. Schoon , Gary G. Rushmeyer
IPC分类号： A61F2/24 , A61B17/00
CPC分类号： A61F2/2427
摘要： A prosthetic heart valve rotator tool operates in the small chest cavity available to the surgeon, having parts that can be easily assembled and disassembled, allowing it to be cleaned and sterilized for repeated use.
摘要翻译：假体心脏瓣膜旋转器工具在外科医生可用的小胸腔中操作，具有易于组装和拆卸的部件，允许其被清洁和消毒以重复使用。

2. 发明授权

US06176877B1 Two piece prosthetic heart valve 失效
标题翻译：两片假体心脏瓣膜
公开(公告)号：US06176877B1
公开(公告)日：2001-01-23
申请号：US09062822
申请日：1998-04-20
申请人： Eric S. Buchanan , Bob Allan , Michael J. Girard , William R. Holmberg , Kimberly A. Anderson
发明人： Eric S. Buchanan , Bob Allan , Michael J. Girard , William R. Holmberg , Kimberly A. Anderson
IPC分类号： A61F224
CPC分类号： A61F2/2427 , A61B17/064 , A61B17/068 , A61B17/072 , A61B17/1155 , A61B2017/0649 , A61B2017/07214 , A61F2/2409 , A61F2250/006
摘要： A prosthetic heart valve for implantation in a heart includes an outer orifice ring for coupling to a tissue annulus of a heart. An inner orifice ring includes at least one leaflet occluder carried in a lumen of the inner orifice ring which is movable between an open position, which allows blood flow through the lumen, and a closed position which blocks blood flow through the lumen. The inner orifice ring is adapted to be coupled to the outer orifice ring after the outer orifice ring has been attached to the tissue annulus.
摘要翻译：用于植入心脏的假心脏瓣膜包括用于联接到心脏组织环的外孔环。内孔环包括携带在内孔环的内腔中的至少一个小叶闭塞器，其能够在允许血液流过内腔的打开位置和阻断通过管腔的血液流动的关闭位置之间移动。在外孔环已经附着到组织环之后，内孔环适于联接到外孔环。

3. 发明授权

US5814101A Holder for heart valve prosthesis 失效
标题翻译：心脏瓣膜假体支架
公开(公告)号：US5814101A
公开(公告)日：1998-09-29
申请号：US719568
申请日：1996-09-25
申请人： Margaret A. Wallner , David R. Elizondo , Kimberly A. Anderson , Guy P. Vanney , Kurt D. Krueger , Michael J. Girard , Stephen A. Petersen , Darrin J. Bergman , Terry L. Shepherd
发明人： Margaret A. Wallner , David R. Elizondo , Kimberly A. Anderson , Guy P. Vanney , Kurt D. Krueger , Michael J. Girard , Stephen A. Petersen , Darrin J. Bergman , Terry L. Shepherd
IPC分类号： A61F2/24 , A61M5/00
CPC分类号： A61F2/2427
摘要： A holder for engaging a heart valve prosthesis during implantation includes a holder body and stem. The stem is adapted to receive a handle used to manipulate the prostheses during implantation. The stem is moveable between a standard implantation position and a low profile delivery position.
摘要翻译：在植入期间用于接合心脏瓣膜假体的保持器包括保持器主体和杆。杆适于在植入期间接收用于操纵假体的手柄。杆可在标准植入位置和低轮廓输送位置之间移动。

4. 发明授权

US5843179A Suture guard for prosthetic heart valve 失效
标题翻译：假体心脏瓣膜缝合护罩
公开(公告)号：US5843179A
公开(公告)日：1998-12-01
申请号：US734360
申请日：1996-10-21
申请人： Guy P. Vanney , Deborah A. Loch , Kimberly A. Anderson , Susan M. Mulvaney , Kurt D. Krueger , Michael J. Girard
发明人： Guy P. Vanney , Deborah A. Loch , Kimberly A. Anderson , Susan M. Mulvaney , Kurt D. Krueger , Michael J. Girard
IPC分类号： A61F2/24
CPC分类号： A61F2/2409
摘要： A heart valve prosthesis for use in a heart includes an orifice defining a lumen therethrough for blood flow. An occluder is carried in the orifice and is movable between an open position which allows blood flow through the lumen and a closed position in which flow through the lumen is blocked. A suture cuff coupled to the orifice extends around an outer circumference of the orifice and is used for attaching the heart valve to a heart tissue annulus using sutures. The sutures are knotted proximate the suture cuff to secure the cuff to the annulus. A suture guard is coupled to the suture cuff and is movable between an open position in which the suture knot is exposed and a closed position in which the suture, suture knot and suture cuff are covered.
摘要翻译：在心脏中使用的心脏瓣膜假体包括限定用于血液流动的腔的孔。封堵器被携带在孔口中，并且可以在允许血液流过管腔的打开位置和闭合位置之间移动，在关闭位置，流过管腔的流动被阻塞。联接到孔的缝合箍围绕孔的外周延伸，并且用于使用缝线将心脏瓣膜附接到心脏组织环。缝合线缝合在缝合袖口附近，以将袖带固定在环状物上。缝合线保护件联接到缝合箍上，并且可以在其中暴露缝合线的打开位置和闭合位置之间移动，缝合线，缝线结和缝合箍被覆盖在闭合位置。

5. 发明授权

US5776187A Combined holder tool and rotator for a prosthetic heart valve 失效
标题翻译：用于假体心脏瓣膜的组合支架工具和旋转器
公开(公告)号：US5776187A
公开(公告)日：1998-07-07
申请号：US692396
申请日：1996-08-05
申请人： Kurt D. Krueger , Averdon M. DeLeon , William S. Nettekoven , Kimberly A. Anderson , Michael J. Girard
发明人： Kurt D. Krueger , Averdon M. DeLeon , William S. Nettekoven , Kimberly A. Anderson , Michael J. Girard
IPC分类号： A61F2/24
CPC分类号： A61F2/2427
摘要： The invention relates to a holder/rotator device which may be used to hold and then rotate a heart valve prosthesis during implantation of the heart valve prosthesis. The device comprises holder/rotator which includes a post and a rotator head, and a handle. The rotator head comprises a gripping surface of a material which engages and grips the surface of the heart valve prosthesis and facilitates the smooth rotation of the valve.
摘要翻译：本发明涉及一种保持器/转子装置，其可用于在心脏瓣膜假体植入期间保持心脏瓣膜假体并随后旋转心脏瓣膜假体。该装置包括保持器/旋转器，其包括柱和旋转头以及手柄。旋转头包括与心脏瓣膜假体接合并夹紧心脏瓣膜假体的表面并有助于瓣膜平滑旋转的材料的抓握表面。

6. 发明授权

US5876436A Rotatable cuff assembly for a heart valve prosthesis 失效
标题翻译：用于心脏瓣膜假体的可旋转袖带组件
公开(公告)号：US5876436A
公开(公告)日：1999-03-02
申请号：US799289
申请日：1997-02-13
申请人： Guy P. Vanney , Michael J. Girard , William R. Kramlinger , Jonas A. Runquist , Kimberly A. Anderson , Scott D. Moore , Bob Allan , James E. Graf
发明人： Guy P. Vanney , Michael J. Girard , William R. Kramlinger , Jonas A. Runquist , Kimberly A. Anderson , Scott D. Moore , Bob Allan , James E. Graf
IPC分类号： A61F2/24
CPC分类号： A61F2/2409 , Y10S623/90
摘要： The invention provides a sewing cuff assembly for mounting to the body of a heart valve prosthesis. The sewing cuff assembly comprises a resiliently deformed spring for exerting a force directed toward the orifice structure. When a torque is applied to the valve, the force results in a rotation-resisting torque sufficient to resist rotation during normal operation of the valve after implantation but low enough to permit assisted rotation, as during surgery.
摘要翻译：本发明提供了一种用于安装到心脏瓣膜假体的身体的缝合袖带组件。缝合袖带组件包括弹性变形的弹簧，用于施加指向孔结构的力。当扭矩施加到阀门时，力将导致旋转阻力转矩足以在植入后阀门的正常操作期间抵抗旋转，但足够低以允许辅助旋转，如在手术期间。

7. 发明授权

US5735842A Low profile manipulators for heart valve prostheses 失效
标题翻译：用于心脏瓣膜假体的低调操纵器
公开(公告)号：US5735842A
公开(公告)日：1998-04-07
申请号：US526530
申请日：1995-09-11
申请人： Kurt D. Krueger , Michael J. Girard , Guy P. Vanney
发明人： Kurt D. Krueger , Michael J. Girard , Guy P. Vanney
IPC分类号： A61M1/10 , A61F2/24 , A61B17/00
CPC分类号： A61F2/2427
摘要： A manipulable low profile heart valve holder that can be pivotally attached to a handle that permits the heart valve holder and a retained heart valve prosthesis to be manipulated remotely during implantation. The heart valve holder is pivotable from a position wherein the plane of the orifice of a retained heart valve is parallel to the axis of the handle, to a second position wherein the plane of the retained heart valve is substantially 90.degree. to the axis of the handle. This pivoting arrangement particularly aids in manipulation of the heart valve prosthesis during implantation using trocars for access to the body cavity. Manipulation is accomplished by having controllable elements on the handle and retained on the exterior of the patient. Manipulation of the heart valve holder also may be done through separate instruments operating through separate trocars.
摘要翻译：可操纵的低轮廓心脏瓣膜保持器，其可枢转地附接到手柄，其允许在植入期间远程操作心脏瓣膜保持器和保留的心脏瓣膜假体。心脏瓣膜保持器可从保持的心脏瓣膜的孔的平面平行于手柄的轴线的位置枢转到第二位置，其中保留的心脏瓣膜的平面基本上相对于处理。该枢转装置特别有助于在植入期间使用套管针进入体腔的操纵心脏瓣膜假体。通过在手柄上具有可控元件并保留在患者的外部来实现操作。心脏瓣膜支架的操作也可以通过使用单独的套管针操作的单独的器械完成。

8. 发明授权

US5843178A Suture guard for annuloplasty ring 失效
标题翻译：缝合护环用于瓣环成形术环
公开(公告)号：US5843178A
公开(公告)日：1998-12-01
申请号：US666254
申请日：1996-06-20
申请人： Guy P. Vanney , Kurt D. Krueger , Michael J. Girard
发明人： Guy P. Vanney , Kurt D. Krueger , Michael J. Girard
IPC分类号： A61F2/24
CPC分类号： A61F2/2445
摘要： An annuloplasty prosthesis ring for implantation proximate a heart valve orifice includes a core having a size and shape to generally conform to the heart valve orifice. A sheath formed about the core is adapted for receiving a suture therethrough to attach the annuloplasty ring to the heart valve orifice. The suture is knotted on a knot surface of the sheath to form a suture knot thereon. A moveable suture guard is provided which is moveable between an open position in which the knot surface and suture knot are exposed and a closed position in which the knot surface and the suture knot carried on the knot surface are covered.
摘要翻译：用于在心脏瓣膜孔附近植入的瓣膜成形假体环包括具有大体上符合心脏瓣膜孔的尺寸和形状的芯。形成在芯周围的护套适于接收穿过其中的缝合线，以将瓣环成形术环附接到心脏瓣膜孔。将缝合线打结在护套的结表面上以在其上形成缝合结。提供可移动的缝合线保护装置，其可以在打结位置和打结位置之间移动，其中结表面和缝线结被暴露在一个打开位置和闭合位置，其中结表面和缝合结被承载在结表面上。

9. 发明授权

US5571175A Suture guard for prosthetic heart valve 失效
标题翻译：假体心脏瓣膜缝合护罩
公开(公告)号：US5571175A
公开(公告)日：1996-11-05
申请号：US487497
申请日：1995-06-07
申请人： Guy Vanney , Kurt D. Krueger , Michael J. Girard
发明人： Guy Vanney , Kurt D. Krueger , Michael J. Girard
IPC分类号： A61F2/24
CPC分类号： A61F2/2409
摘要： An artificial heart valve prosthesis for use in a heart includes an orifice defining a lumen therethrough for blood flow. An occluder is carried in the orifice and is movable between an open position which allows blood flow through the lumen and a closed position in which flow through the lumen is blocked. A suture cuff coupled to the orifice extends around an outer circumference of the orifice and is used for attaching the heart valve to a heart tissue annulus using sutures. The sutures are knotted proximate the suture cuff to secure the cuff to the annulus. A suture guard is coupled to the suture cuff and is movable between an open position in which the suture knot is exposed and a closed position in which the suture, suture knot and suture cuff are covered.
摘要翻译：在心脏中使用的人造心脏瓣膜假体包括限定用于血液流动的腔的孔。封堵器被携带在孔口中，并且可以在允许血液流过管腔的打开位置和闭合位置之间移动，在关闭位置，流过管腔的流动被阻塞。联接到孔的缝合箍围绕孔的外周延伸，并且用于使用缝线将心脏瓣膜附接到心脏组织环。缝合线缝合在缝合袖口附近，以将袖带固定在环状物上。缝合线保护件联接到缝合箍上，并且可以在其中暴露缝合线的打开位置和闭合位置之间移动，缝合线，缝线结和缝合箍被覆盖在闭合位置。

10. 发明授权

US09744031B2 Prosthetic heart valve and endoprosthesis comprising a prosthetic heart valve and a stent 有权
公开(公告)号：US09744031B2
公开(公告)日：2017-08-29
申请号：US13114582
申请日：2011-05-24
申请人： Michael J. Girard , Randy Lane , Arnulf Mayer
发明人： Michael J. Girard , Randy Lane , Arnulf Mayer
IPC分类号： A61F2/24
CPC分类号： A61F2/2412 , A61F2/2418 , A61F2220/0025 , A61F2220/0075 , A61F2240/001
摘要： The invention relates to a prosthetic heart valve (100) for an endoprosthesis (1) used in the treatment of a stenotic cardiac valve and/or a cardiac valve insufficiency. The prosthetic heart valve (100) comprises of a plurality of leaflets (102), which consist of a natural and/or synthetic material and have a first opened position for opening the heart chamber and a second closed position for closing the heart chamber, the leaflets (102) being able to switch between their first and second position in response to the blood flow through the heart. In addition, the prosthetic heart valve (100) comprises a leaflet support portion (103), consisting of biological and/or synthetic material for mounting of the prosthetic heart valve (100) to a stent (10), and a bendable transition area (104) which forms a junction between the leaflets (102) and the leaflet support portion (103), the transition area (104) progressing essentially in a U-shaped manner similar to a cusp shape of a natural aortic or pulmonary heart valve for reducing tissue stresses during opening and closing motion of the leaflets (102). The invention further relates to an endoprosthesis (1) comprising a prosthetic heart valve (100) and a stent (10).

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