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1. 发明授权

US08444606B2 Injection device 有权
标题翻译：注射装置
公开(公告)号：US08444606B2
公开(公告)日：2013-05-21
申请号：US12618318
申请日：2009-11-13
申请人： Bo Radmer , Claus Schmidt Moller , Lars Morch Groth , Klaus Thogersen
发明人： Bo Radmer , Claus Schmidt Moller , Lars Morch Groth , Klaus Thogersen
IPC分类号： A61M5/00
CPC分类号： A61M5/31545 , A61M5/24 , A61M5/31528 , A61M5/31535 , A61M5/31541 , A61M5/31548 , A61M5/3155 , A61M5/31551 , A61M5/31558 , A61M5/31585 , A61M2005/2407 , A61M2005/3125 , A61M2005/3126
摘要： The invention concerns an injection device for apportioning set doses of a drug from a reservoir to a subject. The injection device comprises a housing having an interior thread formed as an outwardly pointing thread carried on an upstanding tower centrally located in the pen shaped device. This outwardly pointing thread forms a first thread connection with the interior thread of the rotatable scale drum. The injection device further comprises a driver for moving the piston rod forward when moved axially. The driver operates the piston rod through a second thread connection having a pitch different than the first thread connection.
摘要翻译：本发明涉及一种用于将药物的设定剂量从储存器分配给受试者的注射装置。注射装置包括具有内螺纹的壳体，内螺纹形成为位于笔形装置中心的直立塔上的向外指向的线。这个向外指向的螺纹形成与可旋转标尺滚筒的内螺纹的第一螺纹连接。注射装置还包括用于当轴向移动时将活塞杆向前移动的驱动器。驾驶员通过具有不同于第一螺纹连接的间距的第二螺纹连接器来操作活塞杆。

2. 发明申请

US20080287883A1 Injection Device 审中-公开
标题翻译：注射装置
公开(公告)号：US20080287883A1
公开(公告)日：2008-11-20
申请号：US11791397
申请日：2005-11-29
申请人： Bo Radmer , Claus Schmidt Moller , Lars Morch Groth , Klaus Thogersen
发明人： Bo Radmer , Claus Schmidt Moller , Lars Morch Groth , Klaus Thogersen
IPC分类号： A61M5/31
CPC分类号： A61M5/31545 , A61M5/24 , A61M5/31528 , A61M5/31535 , A61M5/31541 , A61M5/31548 , A61M5/3155 , A61M5/31551 , A61M5/31558 , A61M5/31585 , A61M2005/2407 , A61M2005/3125 , A61M2005/3126
摘要： The application concerns an injection device for apportioning set doses of a drug from a reservoir (40) to a subject. The injection device comprises a housing having an interior thread (101,112) formed as an outwardly pointing thread (101,112) carried on an upstanding tower centrally located in the pen shaped device. This outwardly pointing thread (101,112) forms a first thread connection with the interior thread of the rotatable scale drum (90). The injection device further comprises a driver (70) for moving the piston rod (120) forward when moved axially. The driver (70) operates the piston rod (120) through a second thread connection having a pitch different than the first thread connection.
摘要翻译：该应用涉及用于将药物的设定剂量从储存器（40）分配给受试者的注射装置。注射装置包括具有内螺纹（101,112）的外壳，内螺纹（101,112）形成为在位于笔形装置中心的直立塔上承载的向外指向的螺纹（101,112）。该向外指向的线（101,112）与可旋转刻度盘（90）的内螺纹形成第一螺纹连接。注射装置还包括用于当轴向移动时将活塞杆（120）向前移动的驱动器（70）。驱动器（70）通过具有不同于第一螺纹连接的间距的第二螺纹连接来操作活塞杆（120）。

3. 发明授权

US07686786B2 Dial-down mechanism for wind-up pen 有权
标题翻译：卷帘笔拨号机构
公开(公告)号：US07686786B2
公开(公告)日：2010-03-30
申请号：US11665486
申请日：2005-10-20
申请人： Claus Schmidt Moller , Christian Peter Enggaard , Bo Radmer , Tom Hede Markussen
发明人： Claus Schmidt Moller , Christian Peter Enggaard , Bo Radmer , Tom Hede Markussen
IPC分类号： A61M5/20
CPC分类号： A61M5/14566 , A61M5/20 , A61M5/31535 , A61M5/3155 , A61M5/31553 , A61M5/31583 , A61M5/31586 , A61M5/31593 , A61M2005/202
摘要： The present invention relates to a dial-down mechanism for an injection device comprising a torsion spring for assisting injection of a dose of medicament from the injection device, the dial-down mechanism comprising dial-up cam arranged to receive and engage with a dial-up key, wherein the dial-up cam and the dial-up key are adapted to, upon rotation of a dose setting member in a first direction, cooperate to strain the torsion spring of the injection device, and a dial-down cam arranged to receive and engage with a dial-down key, wherein the dial-down cam and the dial-down key are adapted to, upon rotation of the dose setting member in a second direction, cooperate to release the torsion spring of the injection device, the second rotation direction being opposite to the first rotation direction.
摘要翻译：本发明涉及一种用于注射装置的减速机构，其包括用于辅助从注射装置喷射剂量的药物的扭转弹簧，所述减速机构包括拨号凸轮，所述拨盘凸轮布置成接收和接合拨号装置，其中所述拨号凸轮和所述拨号键适于在剂量设定构件沿第一方向旋转时协作以使所述注射装置的扭转弹簧变形，并且所述拨号凸轮被布置成接收和接合拨号键，其中拨号凸轮和拨号键适于在剂量设定构件沿第二方向旋转时协作以释放注射装置的扭转弹簧，第二旋转方向与第一旋转方向相反。

4. 再颁专利

USRE41956E1 Dose setting limiter 有权
标题翻译：剂量设定限制器
公开(公告)号：USRE41956E1
公开(公告)日：2010-11-23
申请号：US11122211
申请日：2005-05-04
申请人： Peter Christian Klitgaard , Steffen Hansen , Bo Radmer , Claus Schmidt Moller
发明人： Peter Christian Klitgaard , Steffen Hansen , Bo Radmer , Claus Schmidt Moller
IPC分类号： A61M5/00 , A61M5/178 , A61M5/315
CPC分类号： A61M5/31585 , A61M5/24 , A61M5/31511 , A61M5/31525 , A61M5/31535 , A61M5/31541 , A61M5/31551 , A61M5/31553 , A61M5/31555 , A61M5/31568 , A61M5/31575 , A61M5/3158 , A61M2005/3125 , A61M2005/3126 , A61M2005/31518 , A61M2005/3152
摘要： A limiting mechanism which prevents the setting of a dose, which exceeds the amount of liquid left in a cartridge of an injection device, is disclosed. The injection device is the type where a dose is set by rotating a dose setting member relative to a driver and away from a fixed stop in the injection device. The dose setting member interfaces the driver such that the dose setting member can be rotated in one direction without rotating the driver. The dose is injected by rotating back the dose setting member which during the backward rotation carries the driver with it. Rotating the driver causes the piston rod to move forward inside the cartridge and expel some of the liquid contained in the cartridge. The driver is provided with a track having a length which is related to the total amount of liquid in the cartridge and which track is engaged by a track follower coupled to the dose setting member to follow rotation of this dose setting member. Each time a dose is set and injected, the track follower moves further into the track. When the track follower reaches the end of the track the dose setting member can not be rotated further, and a dose larger than the remaining liquid in the cartridge cannot be set.
摘要翻译：公开了一种限制机构，其防止剂量的设定超过注射装置的药筒中残留的液体量。注射装置是通过相对于驾驶员旋转剂量设定构件并远离注射装置中的固定止动件来设定剂量的类型。剂量设定部件使驱动器接合，使得剂量设定部件能够在一个方向上旋转而不使驾驶员旋转。通过旋转剂量设定构件来注射剂量，在剂量设定构件中，在反向旋转期间携带驾驶员。旋转驱动器使得活塞杆在筒内向前移动并排出容纳在盒中的一些液体。驱动器设置有具有与筒中的液体总量相关的长度的轨道，并且轨道由耦合到剂量设定构件的轨道从动件接合以跟随该剂量设定构件的旋转。每次设定和注入剂量时，跟踪跟随器进一步移动到轨道中。当轨道跟随器到达轨迹的末端时，剂量设定构件不能进一步旋转，并且不能设置大于盒中剩余液体的剂量。

5. 发明申请

US20090012479A1 Injection Device with an End of Dose Feedback Mechanism 有权
标题翻译：注射装置结束剂量反馈机制
公开(公告)号：US20090012479A1
公开(公告)日：2009-01-08
申请号：US11813389
申请日：2006-01-20
申请人： Claus Schmidt Moller , Bo Radmer , Lars Ulrik Nielsen , Christian Peter Engaard
发明人： Claus Schmidt Moller , Bo Radmer , Lars Ulrik Nielsen , Christian Peter Engaard
IPC分类号： A61M5/315
CPC分类号： A61M5/3157 , A61M5/20 , A61M5/24 , A61M5/31535 , A61M5/3155 , A61M5/31551 , A61M5/31561 , A61M5/31585 , A61M2205/581 , A61M2205/582
摘要： An injection device with a dose delivering mechanism being adapted to provide a non-visual, e.g. audible and/or tactile, feedback signal when a set dose has been at least substantially injected. A first and a second part of the injection device are adapted to perform a relative rotational movement with respect to each other. The relative rotational movement causes at least two parts of the injection device to abut or engage, and this abutment or engagement causes the non-visual feedback signal to be generated. A very distinct and precise feedback is provided as compared to prior art axial solutions because the generation of the feedback signal is initiated by the relative rotational movement. Feedback signal may be generated by a change in a rotational velocity of at least one part, e.g. by changing the pitch of a threaded portion or by engaging a non-rotating part and a rotating part, thereby causing the non-rotating part to start rotating. May alternatively be generated by building up and releasing a tension. The injection device is suitable for injecting insulin.
摘要翻译：具有剂量递送机构的注射装置适于提供非视觉的，例如，当至少基本上注入了设定的剂量时，可听和/或触觉的反馈信号。注射装置的第一和第二部分适于执行相对于彼此的相对旋转运动。相对旋转运动导致注射装置的至少两个部分邻接或接合，并且该邻接或接合导致产生非视觉反馈信号。与现有技术的轴向解决方案相比，提供了非常独特和精确的反馈，因为反馈信号的产生是由相对旋转运动引起的。反馈信号可以通过至少一个部分的旋转速度的变化来产生，例如，通过改变螺纹部分的间距或通过接合非旋转部分和旋转部分，从而使非旋转部分开始旋转。或者可以通过建立和释放紧张而产生。注射装置适用于注射胰岛素。

6. 发明申请

US20080147005A1 Dial-Down Mechanism for Wind-Up Pen 有权
标题翻译：卷绕笔的拨号机制
公开(公告)号：US20080147005A1
公开(公告)日：2008-06-19
申请号：US11665486
申请日：2005-10-20
申请人： Claus Schmidt Moller , Christian Peter Enggard , Bo Radmer , Tom Hede Markussen
发明人： Claus Schmidt Moller , Christian Peter Enggard , Bo Radmer , Tom Hede Markussen
IPC分类号： A61M5/142 , A61M5/315
CPC分类号： A61M5/14566 , A61M5/20 , A61M5/31535 , A61M5/3155 , A61M5/31553 , A61M5/31583 , A61M5/31586 , A61M5/31593 , A61M2005/202
摘要： The present invention relates to a dial-down mechanism for an injection device comprising a torsion spring for assisting injection of a dose of medicament from the injection device, the dial-down mechanism comprising dial-up cam arranged to receive and engage with a dial-up key, wherein the dial-up cam and the dial-up key are adapted to, upon rotation of a dose setting member in a first direction, cooperate to strain the torsion spring of the injection device, and a dial-down cam arranged to receive and engage with a dial-down key, wherein the dial-down cam and the dial-down key are adapted to, upon rotation of the dose setting member in a second direction, cooperate to release the torsion spring of the injection device, the second rotation direction being opposite to the first rotation direction.
摘要翻译：本发明涉及一种用于注射装置的减速机构，其包括用于辅助从注射装置喷射剂量的药物的扭转弹簧，所述减速机构包括拨号凸轮，所述拨盘凸轮布置成接收和接合拨号装置，其中所述拨号凸轮和所述拨号键适于在剂量设定构件沿第一方向旋转时协作以使所述注射装置的扭转弹簧变形，并且所述拨号凸轮被布置成接收和接合拨号键，其中拨号凸轮和拨号键适于在剂量设定构件沿第二方向旋转时协作以释放注射装置的扭转弹簧，第二旋转方向与第一旋转方向相反。

7. 发明授权

US09457154B2 Injection device with an end of dose feedback mechanism 有权
标题翻译：注射装置结束剂量反馈机制
公开(公告)号：US09457154B2
公开(公告)日：2016-10-04
申请号：US11813389
申请日：2006-01-20
申请人： Claus Schmidt Moller , Bo Radmer , Lars Ulrik Nielsen , Christian Peter Engaard
发明人： Claus Schmidt Moller , Bo Radmer , Lars Ulrik Nielsen , Christian Peter Engaard
IPC分类号： A61M5/315 , A61M5/24 , A61M5/20
CPC分类号： A61M5/3157 , A61M5/20 , A61M5/24 , A61M5/31535 , A61M5/3155 , A61M5/31551 , A61M5/31561 , A61M5/31585 , A61M2205/581 , A61M2205/582
摘要： An injection device with a dose delivering mechanism being adapted to provide a non-visual, e.g. audible and/or tactile, feedback signal when a set dose has been at least substantially injected. A first and a second part of the injection device are adapted to perform a relative rotational movement with respect to each other. The relative rotational movement causes at least two parts of the injection device to abut or engage, and this abutment or engagement causes the non-visual feedback signal to be generated. A very distinct and precise feedback is provided as compared to prior art axial solutions because the generation of the feedback signal is initiated by the relative rotational movement. Feedback signal may be generated by a change in a rotational velocity of at least one part, e.g. by changing the pitch of a threaded portion or by engaging a non-rotating part and a rotating part, thereby causing the non-rotating part to start rotating. May alternatively be generated by building up and releasing a tension. The injection device is suitable for injecting insulin.
摘要翻译：具有剂量递送机构的注射装置适于提供非视觉的，例如，当至少基本上注入了设定的剂量时，可听和/或触觉的反馈信号。注射装置的第一和第二部分适于执行相对于彼此的相对旋转运动。相对旋转运动导致注射装置的至少两个部分邻接或接合，并且该邻接或接合导致产生非视觉反馈信号。与现有技术的轴向解决方案相比，提供了非常独特和精确的反馈，因为反馈信号的产生是由相对旋转运动引起的。反馈信号可以通过至少一个部分的旋转速度的变化来产生，例如，通过改变螺纹部分的间距或通过接合非旋转部分和旋转部分，从而使非旋转部分开始旋转。或者可以通过建立和释放紧张而产生。注射装置适用于注射胰岛素。

8. 发明申请

US20090054851A1 DOSE SETTING ELEMENT FOR AN INJECTION DEVICE AND HAVING A DOSE SETTING LIMITING MECHANISM 审中-公开
标题翻译：用于注射装置并具有剂量设定限制机构的剂量设定元件
公开(公告)号：US20090054851A1
公开(公告)日：2009-02-26
申请号：US11816435
申请日：2006-02-14
申请人： Bo Radmer , Claus Schmidt Moller
发明人： Bo Radmer , Claus Schmidt Moller
IPC分类号： A61M5/315
CPC分类号： A61M5/31541 , A61M5/31535
摘要： A dose setting element for an injection device, comprising a first part being adapted to rotate during setting of a dose, and a second part being adapted to engage with the first part. Each time the first part has been rotated through a first specific angle the second part is caused to rotate through a second specific angle being smaller than the first specific angle. Keeps track of the total dose set since a cartridge was inserted. When the second part has been rotated a predefined number of times is abuts a stop, thereby preventing further dose setting. Prevents setting of a dose beyond an amount remaining in the cartridge. It is not necessary that part of the limiting mechanism travels a distance corresponding to the total dose due to the two separate parts. This allows the dose setting element and injection device to be small as compared to prior art dose limiting mechanisms. Further, an injection device comprising the dose setting element. Suitable for self-injection, e.g. of insulin.
摘要翻译：一种用于注射装置的剂量设定元件，包括适于在剂量设定期间旋转的第一部分，以及适于与第一部分接合的第二部分。每当第一部分已经旋转第一特定角度时，使第二部分旋转超过小于第一特定角度的第二特定角度。跟踪插入墨盒后的总剂量。当第二部分被旋转时，预定义的次数与停止相关，从而防止进一步的剂量设定。防止剂量超过墨盒中剩余的量。由于两个分开的部分，限制机构的部分不需要相当于总剂量的距离。与现有技术的剂量限制机制相比，这允许剂量设定元件和注射装置小。此外，一种包括剂量设定元件的注射装置。适合自身注射，例如的胰岛素。

9. 发明授权

US11273261B2 Injection device for performing medical injections 有权
公开(公告)号：US11273261B2
公开(公告)日：2022-03-15
申请号：US12865048
申请日：2009-01-20
申请人： Bo Radmer , Jakob Oest Wielandt , Frank Andreas Jespersen , Tom Hede Markussen , Jacob Kollerup Jensen
发明人： Bo Radmer , Jakob Oest Wielandt , Frank Andreas Jespersen , Tom Hede Markussen , Jacob Kollerup Jensen
IPC分类号： A61M5/31 , A61M5/24 , A61M5/315
摘要： The present invention concerns a prefilled injection device having a container and a dose setting mechanism encapsulated inside a housing. The injection device incorporates an axial variable connection such that a distance between a distal end of a piston rod and a plunger is minimized preferably to zero.

10. 发明授权

US09132239B2 Dial-down mechanism for wind-up pen 有权
标题翻译：卷帘笔拨号机构
公开(公告)号：US09132239B2
公开(公告)日：2015-09-15
申请号：US13124995
申请日：2009-10-21
申请人： Claus Schmidt Møller , Tom Hede Markussen , Bo Radmer , Christian Peter Enggaard
发明人： Claus Schmidt Møller , Tom Hede Markussen , Bo Radmer , Christian Peter Enggaard
IPC分类号： A61M5/00 , A61M5/315 , A61M5/20
CPC分类号： A61M5/31525 , A61M5/20 , A61M5/31553 , A61M5/3156
摘要： The present invention relates to a dial-down mechanism for an injection device comprising a torsion spring for assisting injection of a dose of medicament from the injection device, the dial-down mechanism comprising a ratchet arm (21) engaging a ring element (10) and a reset element (30) which acts on a knob located on the periphery of the ratchet arm (21) to move the ratchet arm (21) out of engagement with the ring element (10) in order to allow the set dose to be reduced.
摘要翻译：本发明涉及一种用于注射装置的减速机构，其包括用于辅助从注射装置喷射剂量的药物的扭转弹簧，所述减速机构包括接合环形元件（10）的棘轮臂（21）以及作用在位于所述棘轮臂（21）的周边上的旋钮上的复位元件（30），以使所述棘轮臂（21）与所述环形元件（10）脱离接合，以允许所述设定剂量为减少

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