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1. 发明申请

US20050149084A1 Ablation burr 审中-公开
标题翻译：消融毛刺
公开(公告)号：US20050149084A1
公开(公告)日：2005-07-07
申请号：US11070446
申请日：2005-03-01
申请人： Bill Kanz , Denise Drummond , Robert Barry , Paul Hirst , Mark Wyzgala , Gary Swinford , Edward Wulfman , Tom Clement , Tom Kadavy
发明人： Bill Kanz , Denise Drummond , Robert Barry , Paul Hirst , Mark Wyzgala , Gary Swinford , Edward Wulfman , Tom Clement , Tom Kadavy
IPC分类号： A61B17/00 , A61B17/22 , A61B17/32
CPC分类号： A61B17/320758 , A61B17/320725 , A61B2017/003 , A61B2017/00557 , A61B2017/00867 , A61B2017/320004 , A61B2017/320733 , A61B2017/320766
摘要： A catheter including an elongate drive shaft having a proximal end and a distal end, an ablation burr disposed at the distal end expandable between a first position and a second position, wherein in the second position has a greater transverse dimension than in the first position. The catheter of the present invention can include a mechanism for positioning the burr eccentrically within a vessel lumen. In this context, expansion means that the burr can ablate a lumen having a larger diameter than the diameter of the lumen of the guide catheter to which the device is advanced.
摘要翻译：包括具有近端和远端的细长驱动轴的导管，设置在远端的消融毛刺可在第一位置和第二位置之间扩张，其中在第二位置具有比在第一位置更大的横向尺寸。本发明的导管可以包括用于将毛刺偏心地定位在血管腔内的机构。在这种情况下，膨胀意味着毛刺可以烧蚀具有比该装置前进的导管的内腔直径更大的直径的内腔。

2. 发明授权

US06596005B1 Steerable ablation burr 失效
标题翻译：可导向消融毛刺
公开(公告)号：US06596005B1
公开(公告)日：2003-07-22
申请号：US09670416
申请日：2000-09-26
申请人： Bill Kanz , Denise Drummond , Robert Barry , Paul A. Hirst , Mark Wyzgala , Gary Swinford , Edward Wulfman , Tom Clement , Tom Kadavy
发明人： Bill Kanz , Denise Drummond , Robert Barry , Paul A. Hirst , Mark Wyzgala , Gary Swinford , Edward Wulfman , Tom Clement , Tom Kadavy
IPC分类号： A61D102
CPC分类号： A61B17/320758 , A61B17/320725 , A61B2017/003 , A61B2017/00557 , A61B2017/00867 , A61B2017/320004 , A61B2017/320733 , A61B2017/320766
摘要： A catheter including an elongate drive shaft having a proximal end and a distal end, an ablation burr disposed at the distal end expandable between a first position and a second position, wherein in the second position has a greater transverse dimension than in the first position. The catheter of the present invention can include a mechanism for positioning the burr eccentrically within a vessel lumen. In this context, expansion means that the burr can ablate a lumen having a larger diameter than the diameter of the lumen of the guide catheter to which the device is advanced.
摘要翻译：包括具有近端和远端的细长驱动轴的导管，设置在远端的消融毛刺可在第一位置和第二位置之间扩张，其中在第二位置具有比在第一位置更大的横向尺寸。本发明的导管可以包括用于将毛刺偏心地定位在血管腔内的机构。在这种情况下，膨胀意味着毛刺可以烧蚀具有比该装置前进的导管的内腔直径更大的直径的内腔。

3. 发明授权

US6146395A Ablation burr 失效
标题翻译：消融毛刺
公开(公告)号：US6146395A
公开(公告)日：2000-11-14
申请号：US262502
申请日：1999-03-04
申请人： Bill Kanz , Denise Drummond , Robert Barry , Paul A. Hirst , Mark Wyzgala , Gary Swinford , Edward Wulfman , Tom Clement , Tom Kadavy
发明人： Bill Kanz , Denise Drummond , Robert Barry , Paul A. Hirst , Mark Wyzgala , Gary Swinford , Edward Wulfman , Tom Clement , Tom Kadavy
IPC分类号： A61B17/00 , A61B17/22 , A61B17/32 , A61B1/02
CPC分类号： A61B17/320758 , A61B17/320725 , A61B2017/003 , A61B2017/00557 , A61B2017/00867 , A61B2017/320004 , A61B2017/320733 , A61B2017/320766
摘要： A catheter including an elongate drive shaft having a proximal end and a distal end, an ablation burr disposed at the distal end which can be drawn proximally to engage with a burr deflector surface of the drive shaft in order to be displaced transversely to remove plaque.
摘要翻译：包括具有近端和远端的细长驱动轴的导管，设置在远端处的消融毛刺，其可以向近侧拉伸以与驱动轴的毛刺偏转器表面接合，以横向移位以去除斑块。

4. 发明授权

US06096054A Expandable atherectomy burr and method of ablating an occlusion from a patient's blood vessel 失效
标题翻译：可扩展的粥样斑块切除术和从患者血管中消除闭塞的方法
公开(公告)号：US06096054A
公开(公告)日：2000-08-01
申请号：US178449
申请日：1998-10-23
申请人： Mark Wyzgala , Donald Baumgarten , Lucas S. Gordon , Eric B. Hamilton , Matt Hefner , Tom Hiblar , Edward Wulfman
发明人： Mark Wyzgala , Donald Baumgarten , Lucas S. Gordon , Eric B. Hamilton , Matt Hefner , Tom Hiblar , Edward Wulfman
IPC分类号： A61B17/00 , A61B17/22 , A61B17/32
CPC分类号： A61B17/320725 , A61B17/320758 , A61B2017/00557 , A61B2017/00867 , A61B2017/320004 , A61B2017/320733
摘要： An atherectomy burr has an operating diameter that is larger than the diameter of a catheter in which the burr is routed. The burr may include a polymeric balloon that is coated with an abrasive and that expands when the burr is rotated. Alternatively, the burr may include a polymeric tube that is coated with an abrasive and secured to the proximal end of the burr. When the burr is rotated, the polymeric tube expands by centrifugal force. Alternatively, the burr may comprise a metallic strip wound over a mandrel. When the strip is tightly coiled to the mandrel, its outer diameter decreases. The outer diameter of the burr increases as the metallic strip expands. In addition, the burr can be formed as a wire spring wound over a drive tube. The distal end of the spring is coupled to a nose cone that can move within a distal lumen in the drive tube. The maximum expansion of the burr is controlled by the distance that the nose cone can be retracted into the lumen. In addition, the present invention includes a burr having an indexable outer diameter. Various indexing mechanisms are disclosed for selectively increasing or decreasing the distance between a proximal and distal end of the burr. As the length of the burr changes, the outer diameter of a number of cutting blades is changed to allow a physician to create different sized lumens in a patient's vessel.
摘要翻译：粥样斑块切除术毛刺的操作直径大于其中布置毛刺的导管的直径。毛刺可以包括涂覆有磨料的聚合物气球，并且当毛刺旋转时膨胀。或者，毛刺可以包括涂覆有研磨剂并固定到毛刺的近端的聚合物管。当毛刺旋转时，聚合物管通过离心力膨胀。或者，毛刺可以包括缠绕在心轴上的金属条。当条带紧紧地卷绕到心轴上时，其外径减小。毛边的外径随着金属条扩张而增加。此外，毛刺可以形成为卷绕在驱动管上的线弹簧。弹簧的远端联接到能够在驱动管内远端管腔内移动的鼻锥体。毛刺的最大膨胀由鼻锥可以缩回到内腔的距离来控制。此外，本发明包括具有可转位外径的毛刺。公开了用于选择性地增加或减小毛刺的近端和远端之间的距离的各种分度机构。随着毛刺的长度改变，许多切割刀片的外径被改变以允许医师在患者的血管中产生不同大小的腔。

5. 发明授权

US06416526B1 Expandable atherectomy burr 失效
标题翻译：扩张性粥样斑块切除术
公开(公告)号：US06416526B1
公开(公告)日：2002-07-09
申请号：US09589861
申请日：2000-06-08
申请人： Mark Wyzgala , Donald Baumgarten , Lucas S. Gordon , Eric B. Hamilton , Matt Hefner , Tom Hiblar , Edward Wulfman
发明人： Mark Wyzgala , Donald Baumgarten , Lucas S. Gordon , Eric B. Hamilton , Matt Hefner , Tom Hiblar , Edward Wulfman
IPC分类号： A61B1732
CPC分类号： A61B17/320725 , A61B17/320758 , A61B2017/00557 , A61B2017/00867 , A61B2017/320004 , A61B2017/320733
摘要： An atherectomy burr has an operating diameter that is larger than the diameter of a catheter in which the burr is routed. The burr may include a polymeric balloon that is coated with an abrasive and that expands when the burr is rotated. Alternatively, the burr may include a polymeric tube that is coated with an abrasive and secured to the proximal end of the burr. When the burr is rotated, the polymeric tube expands by centrifugal force. Alternatively, the burr may comprise a metallic strip wound over a mandrel. When the strip is tightly coiled to the mandrel, its outer diameter decreases. The outer diameter of the burr increases as the metallic strip expands. In addition, the burr can be formed as a wire spring wound over a drive tube. The distal end of the spring is coupled to a nose cone that can move within a distal lumen in the drive tube. The maximum expansion of the burr is controlled by the distance that the nose cone can be retracted into the lumen. In addition, the present invention includes a burr having an indexable outer diameter. Various indexing mechanisms are disclosed for selectively increasing or decreasing the distance between a proximal and distal end of the burr. As the length of the burr changes, the outer diameter of a number of cutting blades is changed to allow a physician to create different sized lumens in a patient's vessel.
摘要翻译：粥样斑块切除术毛刺的操作直径大于其中布置毛刺的导管的直径。毛刺可以包括涂覆有磨料的聚合物气球，并且当毛刺旋转时膨胀。或者，毛刺可以包括涂覆有研磨剂并固定到毛刺的近端的聚合物管。当毛刺旋转时，聚合物管通过离心力膨胀。或者，毛刺可以包括缠绕在心轴上的金属条。当条带紧紧地卷绕到心轴上时，其外径减小。毛边的外径随着金属条扩张而增加。此外，毛刺可以形成为卷绕在驱动管上的线弹簧。弹簧的远端联接到能够在驱动管内远端管腔内移动的鼻锥体。毛刺的最大膨胀由鼻锥可以缩回到内腔的距离来控制。此外，本发明包括具有可转位外径的毛刺。公开了用于选择性地增加或减小毛刺的近端和远端之间的距离的各种分度机构。随着毛刺的长度改变，许多切割刀片的外径被改变以允许医师在患者的血管中产生不同大小的腔。

6. 发明授权

US6156048A Atherectomy device for reducing damage to vessels and/or in-vivo stents 失效
公开(公告)号：US6156048A
公开(公告)日：2000-12-05
申请号：US365188
申请日：1999-08-02
申请人： Edward Wulfman , Lucas Gordon , Robert Barry , Brandon Shuman , David Dillard , Verivada Chandrasekaran
发明人： Edward Wulfman , Lucas Gordon , Robert Barry , Brandon Shuman , David Dillard , Verivada Chandrasekaran
IPC分类号： A61B17/32 , A61B17/22
CPC分类号： A61B17/320758 , A61B2017/320004
摘要： An atherectomy device that may reduce the risk of damage to a vessel wall. One rotatable atherectomy burr has a recessed material removal portion lying between less abrasive proximal and distal shoulders. The shoulders can have a straight, rounded or elliptical taper. The shoulders can perform a cam action when the burr is canted is a vessel, as when passing the burr and guide wire through a tortuous, stenosed vessel path. The shoulders act to align the burr with the path through the vessel, presenting the less abrasive shoulders to the vessel wall while presenting the abrasive portion to a stenosis.

7. 发明授权

US6015420A Atherectomy device for reducing damage to vessels and/or in-vivo stents 失效
标题翻译：用于减少对血管和/或体内支架的损伤的动脉粥样硬化切除装置
公开(公告)号：US6015420A
公开(公告)日：2000-01-18
申请号：US35734
申请日：1998-03-05
申请人： Edward Wulfman , Lucas Gordon , Robert Barry , Brandon Shuman , David Dillard , Verivada Chandrasekaran
发明人： Edward Wulfman , Lucas Gordon , Robert Barry , Brandon Shuman , David Dillard , Verivada Chandrasekaran
IPC分类号： A61B17/32 , A61B17/22
CPC分类号： A61B17/320758 , A61B2017/320004
摘要： An atherectomy device that may reduce the risk of damage to a vessel wall. One rotatable atherectomy burr has a recessed material removal portion lying between less abrasive proximal and distal shoulders. The shoulders can have a straight, rounded or elliptical taper. The shoulders can perform a cam action when the burr is canted is a vessel, as when passing the burr and guide wire through a tortuous, stenosed vessel path. The shoulders act to align the burr with the path through the vessel, presenting the less abrasive shoulders to the vessel wall while presenting the abrasive portion to a stenosis.
摘要翻译：可以减少损伤血管壁的风险的粥样斑块切除装置。一个可旋转的粥样斑块切除术毛刺具有凹陷的材料去除部分，位于不太磨蚀的近端和远端之间。肩部可以有一个直的圆形或椭圆形的锥形。当毛刺倾斜是船只时，肩膀可以执行凸轮动作，当通过毛刺和引导线通过曲折，狭窄的血管路径时。肩部的作用是将毛刺与通过血管的路径对齐，将较小的磨砂肩膀呈现在血管壁上，同时使研磨部分呈狭窄。

8. 发明授权

US06258109B1 Guidewire bearing to prevent darting 失效
标题翻译：导丝轴承，防止飞镖
公开(公告)号：US06258109B1
公开(公告)日：2001-07-10
申请号：US09656339
申请日：2000-09-06
申请人： Robert Lawrence Barry , Matt Hefner , Tom Hiblar , Joseph Pearce , Natalya Peskin , Edward Wulfman
发明人： Robert Lawrence Barry , Matt Hefner , Tom Hiblar , Joseph Pearce , Natalya Peskin , Edward Wulfman
IPC分类号： A61B1722
CPC分类号： A61B17/320758 , A61B2017/320004
摘要： A guide wire for use in atherectomy procedures has a bearing with a static member fixedly secured to the guide wire and a dynamic member rotatably engaged to the static member. The dynamic member can rotate with an atherectomy burr if the burr engages the bearing.
摘要翻译：用于粥样斑块切除术的导丝具有固定在引导线上的静止部件和与该静止部件可旋转接合的动力部件的轴承。如果毛刺接合轴承，动态构件可以用粥状斑切除术毛发旋转。

9. 发明授权

US06299623B1 Atherectomy burr including a bias wire 有权
标题翻译：动脉粥样硬化斑块包括偏心线
公开(公告)号：US06299623B1
公开(公告)日：2001-10-09
申请号：US09589993
申请日：2000-06-08
申请人： Edward Wulfman
发明人： Edward Wulfman
IPC分类号： A61B1722
CPC分类号： A61B17/320758 , A61B2017/22039 , A61B2017/320004
摘要： An ablation device (10) includes a drive shaft (12) and an ablation burr (14) secured to the distal end of the drive shaft thereto. A guide wire (18) extends through the drive shaft and the ablation burr. To direct the ablation burr laterally within a patient's vessel, the atherectomy device includes one or more bias wires (30) that extend generally parallel to and spaced from the longitudinal axis of the drive shaft such that engagement of the bias wires against an obstruction in a patient's vessel will force the ablation burr to move laterally within a patient's blood vessel. To rotate the bias wires in a patient's blood vessel, the bias wire may be coupled to a catheter surrounding the drive shaft. Alternatively, the catheter is designed to engage the bias wires when the drive shaft is retracted into the catheter. The bias wires will then rotate as the catheter is rotated.
摘要翻译：消融装置（10）包括固定到驱动轴的远端的驱动轴（12）和消融毛刺（14）。引导线（18）延伸穿过驱动轴和消融毛刺。为了将消融毛刺横向地引导到患者的血管内，动脉粥样斑块切除装置包括一个或多个偏置线（30），该偏置线大致平行于驱动轴的纵向轴线延伸并且与驱动轴的纵向轴线间隔开，使得偏置线与阻塞患者的血管将迫使消融毛刺在患者的血管内横向移动。为了使患者血管中的偏置线旋转，偏置线可以联接到围绕驱动轴的导管。或者，当驱动轴缩回到导管中时，导管被设计成接合偏置线。然后当导管旋转时，偏置线将旋转。

10. 发明授权

US06800083B2 Compressible atherectomy burr 有权
标题翻译：可压缩粥样斑块切除术
公开(公告)号：US06800083B2
公开(公告)日：2004-10-05
申请号：US09829486
申请日：2001-04-09
申请人： Thomas J. Hiblar , Robert L. Barry , Edward Wulfman , Zihong Guo , Verivada Chandru Chandrasekaran
发明人： Thomas J. Hiblar , Robert L. Barry , Edward Wulfman , Zihong Guo , Verivada Chandru Chandrasekaran
IPC分类号： A61B1732
CPC分类号： A61B17/320758 , A61B17/320725 , A61B2017/320004
摘要： A rotational ablation atherectomy device including a flexible drive shaft and a compressible burr that may be inserted and extracted from a patient using a catheter having a diameter that is smaller than the operational diameter of the burr. In one embodiment, the burr includes a nose portion coupled to the drive shaft and one or more flexible abrasive disks disposed rearwardly from the nose portion. The flexible disks are foldable to be slidably received within a catheter. In another embodiment, the burr includes a support member coupled to the drive shaft, the support member having a resilient panel that spirals outwardly, forming a generally cylindrical ablation surface. The flexible panel can be elastically urged toward the support member and slidably inserted into the catheter. In a third embodiment, the burr includes a plurality of struts that are coupled to the drive shaft. An elastically compressible body disposed between the struts permits the struts to flex inwardly to reduce the burr diameter. In another embodiment, the burr includes a plurality of flexible wires attached at proximal and distal ends to the drive shaft. An abrasive sheath is disposed over the wires. The wires can be bent inwardly to compress the burr and re-expanded by rotation of the burr. In another embodiment, the burr comprises a nose portion and a resilient shell having a compressible, larger diameter abrasive section disposed at the proximal end of the nose portion.
摘要翻译：包括柔性驱动轴和可压缩毛刺的旋转消融粥样斑块切除装置，其可以使用直径小于毛刺的操作直径的导管从患者插入和拔出。在一个实施例中，毛刺包括联接到驱动轴的鼻部和从鼻部向后设置的一个或多个柔性研磨盘。柔性盘可折叠成可滑动地容纳在导管内。在另一个实施例中，毛刺包括联接到驱动轴的支撑构件，支撑构件具有向外螺旋的弹性面板，形成大致圆柱形的烧蚀表面。柔性面板可以弹性地推向支撑构件并且可滑动地插入导管中。在第三实施例中，毛刺包括联接到驱动轴的多个支柱。设置在支柱之间的可弹性压缩体允许支柱向内弯曲以减小毛刺直径。在另一个实施例中，毛刺包括在近端和远端附接到驱动轴的多个柔性线。研磨护套设置在电线上。电线可以向内弯曲以压缩毛刺并通过毛刺的旋转而重新膨胀。在另一个实施例中，毛刺包括鼻部和弹性壳，弹性壳具有设置在鼻部的近端的可压缩的较大直径的研磨部。

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