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    • 1. 发明授权
    • Compressible atherectomy burr
    • 可压缩粥样斑块切除术
    • US06800083B2
    • 2004-10-05
    • US09829486
    • 2001-04-09
    • Thomas J. HiblarRobert L. BarryEdward WulfmanZihong GuoVerivada Chandru Chandrasekaran
    • Thomas J. HiblarRobert L. BarryEdward WulfmanZihong GuoVerivada Chandru Chandrasekaran
    • A61B1732
    • A61B17/320758A61B17/320725A61B2017/320004
    • A rotational ablation atherectomy device including a flexible drive shaft and a compressible burr that may be inserted and extracted from a patient using a catheter having a diameter that is smaller than the operational diameter of the burr. In one embodiment, the burr includes a nose portion coupled to the drive shaft and one or more flexible abrasive disks disposed rearwardly from the nose portion. The flexible disks are foldable to be slidably received within a catheter. In another embodiment, the burr includes a support member coupled to the drive shaft, the support member having a resilient panel that spirals outwardly, forming a generally cylindrical ablation surface. The flexible panel can be elastically urged toward the support member and slidably inserted into the catheter. In a third embodiment, the burr includes a plurality of struts that are coupled to the drive shaft. An elastically compressible body disposed between the struts permits the struts to flex inwardly to reduce the burr diameter. In another embodiment, the burr includes a plurality of flexible wires attached at proximal and distal ends to the drive shaft. An abrasive sheath is disposed over the wires. The wires can be bent inwardly to compress the burr and re-expanded by rotation of the burr. In another embodiment, the burr comprises a nose portion and a resilient shell having a compressible, larger diameter abrasive section disposed at the proximal end of the nose portion.
    • 包括柔性驱动轴和可压缩毛刺的旋转消融粥样斑块切除装置,其可以使用直径小于毛刺的操作直径的导管从患者插入和拔出。 在一个实施例中,毛刺包括联接到驱动轴的鼻部和从鼻部向后设置的一个或多个柔性研磨盘。 柔性盘可折叠成可滑动地容纳在导管内。 在另一个实施例中,毛刺包括联接到驱动轴的支撑构件,支撑构件具有向外螺旋的弹性面板,形成大致圆柱形的烧蚀表面。 柔性面板可以弹性地推向支撑构件并且可滑动地插入导管中。 在第三实施例中,毛刺包括联接到驱动轴的多个支柱。 设置在支柱之间的可弹性压缩体允许支柱向内弯曲以减小毛刺直径。 在另一个实施例中,毛刺包括在近端和远端附接到驱动轴的多个柔性线。 研磨护套设置在电线上。 电线可以向内弯曲以压缩毛刺并通过毛刺的旋转而重新膨胀。 在另一个实施例中,毛刺包括鼻部和弹性壳,弹性壳具有设置在鼻部的近端的可压缩的较大直径的研磨部。
    • 7. 发明授权
    • Light transmission system for photoreactive therapy
    • 用于光反应治疗的光传输系统
    • US08235975B2
    • 2012-08-07
    • US13274192
    • 2011-10-14
    • James C. ChenSteven R. DalyZihong GuoLlew KeltnerJeffrey R. Storm
    • James C. ChenSteven R. DalyZihong GuoLlew KeltnerJeffrey R. Storm
    • A61B18/18
    • A61N5/062A61B50/30A61N5/0601A61N2005/0645A61N2005/0652
    • A light transmission system to provide photodynamic treatment to a patient includes a single use integrated control module and catheter assembly having a plurality of light emitting diodes (LEDs) to transmit light toward target cells within a patient. The integrated light catheter and control module are used in combination with a light activated drug. Selected operating parameters may be programmed into the control module, or it may be wirelessly programmable in situ prior to use to allow user flexibility to tailor treatment for a particular patient or condition. Among the features that prevent reuse are that the control module lacks access to recharge the power source, and it may include a deactivation module that destroys circuitry or software when triggered. To prevent patient interference when in use, the control module may also be configured to selectively deactivate.
    • 向患者提供光动力治疗的光传输系统包括具有多个发光二极管(LED)的单次使用的集成控制模块和导管组件,以将光传送到患者体内的靶细胞。 集成光导管和控制模块与光活化药物组合使用。 所选择的操作参数可以被编程到控制模块中,或者可以在使用之前在现场进行无线可编程,以允许用户灵活地为特定患者或病症定制治疗。 防止重用的功能之一是控制模块缺少对电源进行再充电的功能,并且可能包括在触发时破坏电路或软件的停用模块。 为了在使用时防止患者干扰,控制模块还可以被配置为选择性地停用。
    • 8. 发明申请
    • LIGHT TRANSMISSION SYSTEM FOR PHOTOREACTIVE THERAPY
    • 用于光敏治疗的光传输系统
    • US20120089207A1
    • 2012-04-12
    • US13274192
    • 2011-10-14
    • James C. ChenSteven R. DalyZihong GuoLlew KeltnerJeffrey R. Storm
    • James C. ChenSteven R. DalyZihong GuoLlew KeltnerJeffrey R. Storm
    • A61N5/06
    • A61N5/062A61B50/30A61N5/0601A61N2005/0645A61N2005/0652
    • A light transmission system to provide photodynamic treatment to a patient includes a single use integrated control module and catheter assembly having a plurality of light emitting diodes (LEDs) to transmit light toward target cells within a patient. The integrated light catheter and control module are used in combination with a light activated drug. Selected operating parameters may be programmed into the control module, or it may be wirelessly programmable in situ prior to use to allow user flexibility to tailor treatment for a particular patient or condition. Among the features that prevent reuse are that the control module lacks access to recharge the power source, and it may include a deactivation module that destroys circuitry or software when triggered. To prevent patient interference when in use, the control module may also be configured to selectively deactivate.
    • 向患者提供光动力治疗的光传输系统包括具有多个发光二极管(LED)的单次使用的集成控制模块和导管组件,以将光传送到患者体内的靶细胞。 集成光导管和控制模块与光活化药物组合使用。 所选择的操作参数可以被编程到控制模块中,或者可以在使用之前在现场进行无线可编程,以允许用户灵活地为特定患者或病症定制治疗。 防止重用的功能之一是控制模块缺少对电源进行再充电的功能,并且可能包括在触发时破坏电路或软件的停用模块。 为了在使用时防止患者干扰,控制模块还可以被配置为选择性地停用。