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1. 发明授权

US06878358B2 Process for removing mercury from flue gases 有权
标题翻译：从烟道气中去除汞的工艺
公开(公告)号：US06878358B2
公开(公告)日：2005-04-12
申请号：US10430088
申请日：2003-05-06
申请人： Bernhard Vosteen , Joachim Beyer , Theodore-Gerhard Bonkhofer , Olaf Fleth , Andrea Wieland , Andreas Pohontsch , Rico Kanefke , Ewa Standau , Claus Mueller , Michael Nolte , Heinz Koeser
发明人： Bernhard Vosteen , Joachim Beyer , Theodore-Gerhard Bonkhofer , Olaf Fleth , Andrea Wieland , Andreas Pohontsch , Rico Kanefke , Ewa Standau , Claus Mueller , Michael Nolte , Heinz Koeser
IPC分类号： B01D53/64 , B01D53/00 , C22B43/00
CPC分类号： B01D53/64
摘要： Process for removing mercury from flue gases of high-temperature plants, in particular power stations and waste incineration plants in which a bromine compound is fed to the multistage furnace and/or the flue gas in a plant section downstream of the furnace, the temperature during contact of the bromine compound with the flue gas being at least 500° C., preferably at least 800° C. The combustion is carried out in the presence of a sulphur compound, in particular sulphur dioxide. Subsequently to the furnace, the flue gas is subjected to an optional multistage cleanup for removing mercury from the flue gas, which cleanup comprises a wet scrubber and/or a dry cleanup.
摘要翻译：在高温设备，特别是发电厂和废物焚烧厂的烟道气中除去汞的方法，其中溴化合物被送入炉内下游的一个工厂段中的多级炉和/或烟道气，溴化合物与烟道气的接触为至少500℃，优选至少800℃。燃烧在硫化合物，特别是二氧化硫的存在下进行。在炉后，对废气进行可选的多级清理以从烟道气中去除汞，该净化包括湿式洗涤器和/或干式清洗。

2. 发明申请

US20130303514A1 2-METHOXY-PYRIDIN-4-YL-DERIVATIVES 有权
标题翻译： 2-甲氧基 - 吡啶-4-基衍生物
公开(公告)号：US20130303514A1
公开(公告)日：2013-11-14
申请号：US13980764
申请日：2012-01-18
申请人： Martin Bolli , Cyrille Lescop , Boris Mathys , Keith Morrison , Claus Mueller , Oliver Nayler , Beat Steiner
发明人： Martin Bolli , Cyrille Lescop , Boris Mathys , Keith Morrison , Claus Mueller , Oliver Nayler , Beat Steiner
IPC分类号： C07D413/14 , C07D413/04
CPC分类号： C07D413/14 , C07D413/04
摘要： The invention relates to pyridine derivatives of Formula (I) wherein A, R1, R2, R3, and R4 are as described in the description, their preparation and their use as pharmaceutically active compounds. Said compounds particularly act as immunomodulating agents.
摘要翻译：本发明涉及式（I）的吡啶衍生物，其中A，R 1，R 2，R 3和R 4如说明书中所述，其制备及其作为药物活性化合物的用途。所述化合物特别充当免疫调节剂。

3. 发明授权

US08410151B2 Aminomethyl benzene derivatives 失效
标题翻译：氨甲基苯衍生物
公开(公告)号：US08410151B2
公开(公告)日：2013-04-02
申请号：US12920574
申请日：2009-03-03
申请人： Martin Bolli , Cyrille Lescop , Boris Mathys , Claus Mueller , Oliver Nayler , Beat Steiner
发明人： Martin Bolli , Cyrille Lescop , Boris Mathys , Claus Mueller , Oliver Nayler , Beat Steiner
IPC分类号： A61K31/4245 , C07D271/06
CPC分类号： C07D271/06
摘要： The invention relates to novel aminomethyl benzene derivatives, their preparation and their use as pharmaceutically active compounds. Said compounds particularly act as immunomodulating agents.
摘要翻译：本发明涉及新型氨基甲基苯衍生物，其制备及其作为药物活性化合物的用途。所述化合物特别充当免疫调节剂。

4. 发明授权

US08273779B2 Thiazolidin 4-one derivatives 有权
标题翻译：噻唑烷-4-酮衍生物
公开(公告)号：US08273779B2
公开(公告)日：2012-09-25
申请号：US12496945
申请日：2009-07-02
申请人： Christoph Binkert , Martin Bolli , Boris Mathys , Claus Mueller , Michael Scherz , Oliver Nayler
发明人： Christoph Binkert , Martin Bolli , Boris Mathys , Claus Mueller , Michael Scherz , Oliver Nayler
IPC分类号： A61K31/41 , A01N43/82 , C07D277/00 , C07D327/04 , C07D343/00
CPC分类号： C07D277/54 , A61K31/426 , C07D277/20 , C07D277/42 , C07D417/06
摘要： The invention relates to pharmaceutical compositions containing at least one thiazolidin-4-one derivative to prevent or treat disorders associated with an activated immune system. Furthermore, the invention relates to novel thiazolidin-4-one derivatives notably for use as pharmaceutically active compounds. Said compounds particularly act also as immunosuppressive agents.
摘要翻译：本发明涉及含有至少一种噻唑烷-4-酮衍生物以预防或治疗与活化的免疫系统相关的疾病的药物组合物。此外，本发明涉及特别用作药物活性化合物的新型噻唑烷-4-酮衍生物。所述化合物还特别用作免疫抑制剂。

5. 发明申请

US20120195930A1 NOVEL PYRIDINE DERIVATIVES 失效
标题翻译：新型吡啶衍生物
公开(公告)号：US20120195930A1
公开(公告)日：2012-08-02
申请号：US13438657
申请日：2012-04-03
申请人： Martin Bolli , David Lehmann , Boris Mathys , Claus Mueller , Oliver Nayler , Beat Steiner , Jörg Velker
发明人： Martin Bolli , David Lehmann , Boris Mathys , Claus Mueller , Oliver Nayler , Beat Steiner , Jörg Velker
IPC分类号： A61K31/4439 , A61P37/06 , A61P25/00 , A61P17/00 , A61P17/06 , A61P1/00 , A61P29/00 , C07D413/14 , A61P19/02
CPC分类号： C07D409/06 , C07D413/14
摘要： The invention relates to novel pyridine derivatives, their preparation and their use as pharmaceutically active compounds. Said compounds particularly act as immunosuppressive agents.
摘要翻译：本发明涉及新颖的吡啶衍生物，其制备及其作为药物活性化合物的用途。所述化合物特别充当免疫抑制剂。

6. 发明申请

US20110028448A1 PYRIDINE COMPOUNDS 审中-公开
标题翻译：吡啶化合物
公开(公告)号：US20110028448A1
公开(公告)日：2011-02-03
申请号：US12920569
申请日：2009-03-03
申请人： Martin Bolli , Cyrille Lescop , Boris Mathys , Claus Mueller , Oliver Nayler , Beat Steiner
发明人： Martin Bolli , Cyrille Lescop , Boris Mathys , Claus Mueller , Oliver Nayler , Beat Steiner
IPC分类号： A61K31/4439 , C07D413/04 , C07D413/14 , A61P11/06 , A61P29/00 , A61P17/06 , A61P25/00 , A61P3/10 , A61P35/00 , A61P35/04
CPC分类号： C07D413/04
摘要： The invention relates to pyridine compounds, their preparation and their use as pharmaceutically active compounds. Said compounds particularly act as immunomodulating agents.
摘要翻译：本发明涉及吡啶化合物，其制备及其作为药物活性化合物的用途。所述化合物特别充当免疫调节剂。

7. 发明申请

US20100240717A1 NOVEL THIOPHENE DERIVATIVES AS S1P1/EDG1 RECEPTOR AGONISTS 有权
标题翻译：新型的THIOPHENE衍生物作为S1P1 / EDG1受体激动剂
公开(公告)号：US20100240717A1
公开(公告)日：2010-09-23
申请号：US12160520
申请日：2007-01-10
申请人： Martin Boli , David Lehmann , Boris Mathys , Claus Mueller , Oliver Nayler , Beat Steiner , Jörg Velker
发明人： Martin Boli , David Lehmann , Boris Mathys , Claus Mueller , Oliver Nayler , Beat Steiner , Jörg Velker
IPC分类号： A61K31/381 , C07D333/22 , C07D413/04 , C07D333/24 , A61K31/4245 , A61P37/00 , A61P29/00 , A61P17/00 , A61P11/06 , A61P3/10
CPC分类号： C07D333/22 , C07D413/04
摘要： The invention relates to thiophene derivatives of formula (I)/their preparation and their use as pharmaceutically active compounds. Said compounds particularly act as immunosuppressive agents wherein: A represents *—CO—CH═CH—, *—CO—CH2CH2—, *—CO—CH2—NH—, wherein the sterisks indicate the bond that is linked to the thiophene group of Formula (I), and R1-R3 are as defined in the claims.
摘要翻译：本发明涉及式（I）的噻吩衍生物/其制备及其作为药物活性化合物的用途。所述化合物特别充当免疫抑制剂，其中：A表示* -CO-CH = CH-，* -CO-CH 2 CH 2 - ，* -CO-CH 2 -NH-，其中所述甾体表示与噻吩基团连接的键式（I）和R 1 -R 3如权利要求中所定义。

8. 发明授权

US07750040B2 Thiophene derivatives 失效
标题翻译：噻吩衍生物
公开(公告)号：US07750040B2
公开(公告)日：2010-07-06
申请号：US11572801
申请日：2005-07-20
申请人： Martin Bolli , Daniel Bur , Martine Clozel , Walter Fischli , David Lehmann , Boris Mathys , Claus Mueller , Oliver Nayler , Michael Scherz , Thomas Weller
发明人： Martin Bolli , Daniel Bur , Martine Clozel , Walter Fischli , David Lehmann , Boris Mathys , Claus Mueller , Oliver Nayler , Michael Scherz , Thomas Weller
IPC分类号： A61K31/381 , C07D333/78
CPC分类号： C07D333/78 , C07D409/12
摘要： The invention relates to novel thiophene derivatives, their preparation and their use as pharmaceutically active compounds. Said compounds particularly act as immunosuppressive agents.
摘要翻译：本发明涉及新的噻吩衍生物，其制备及其作为药物活性化合物的用途。所述化合物特别充当免疫抑制剂。

9. 发明申请

US20090041607A1 Method for the production of a sealing segment, and sealing segment to be use in compressor and turbine components 审中-公开
标题翻译：用于生产密封段的方法和用于压缩机和涡轮机部件的密封段
公开(公告)号：US20090041607A1
公开(公告)日：2009-02-12
申请号：US12224681
申请日：2007-02-27
申请人： Reinhold Meier , Claus Mueller , Franz Prieschl , Siegfried Sikorski
发明人： Reinhold Meier , Claus Mueller , Franz Prieschl , Siegfried Sikorski
IPC分类号： B22F5/04
CPC分类号： B22F5/009 , B22F3/225 , B22F7/062 , B22F2998/10 , B28B1/002 , B28B1/24 , C04B35/638 , C04B37/021 , C04B2235/6027 , C04B2237/34 , C04B2237/341 , C04B2237/36 , C04B2237/361 , C04B2237/363 , C04B2237/40 , F23R2900/00018 , B22F3/1021
摘要： A method is provided for producing a sealing segment for use in compressor and turbine components, by powder injection molding, the method comprising the following steps: a) preparing a first homogeneous mixture of a metal powder or a mixture of metal powders or a ceramic powder or a mixture of ceramic powders and at least one binding agent; b) producing a first molded article by injection molding the first mixture; c) preparing a second homogeneous mixture of a metal powder or a mixture of metal powders or a ceramic powder or a mixture of ceramic powders and at least one binding agent, the second mixture being selected to exhibit a lower abrasion resistance than the first mixture following a subsequent joint sintering process; d) producing a second molded article as a rub strip by injection molding the second mixture; and e) joining the first and second molded articles to produce the sealing segment. A sealing segment is also provided for use in compressor and turbine components, composed of at least one first molded article as a base element and at least one second molded article having lower abrasion resistance than the first molded article, as a rub strip, the first and the second molded articles each being produced by powder injection molding.
摘要翻译：提供一种通过粉末注射成型制造用于压缩机和涡轮机部件的密封段的方法，该方法包括以下步骤：a）制备金属粉末或金属粉末或陶瓷粉末的混合物的第一均匀混合物或陶瓷粉末和至少一种粘合剂的混合物; b）通过注塑第一混合物制备第一模塑制品; c）制备金属粉末或金属粉末或陶瓷粉末或陶瓷粉末和至少一种粘合剂的混合物的混合物的第二均匀混合物，选择第二混合物以显示比第一混合物更低的耐磨性随后的联合烧结工艺; d）通过注射第二混合物制备作为摩擦条的第二模塑制品; 和e）连接第一和第二模制品以产生密封段。还提供一种用于压缩机和涡轮机部件的密封部分，其由至少一个第一模制品作为基础元件和至少一个具有比第一模塑制品低的耐磨性的第二模制品作为摩擦条，第一并且第二模制品各自通过粉末注射成型制造。

10. 发明授权

US07375227B2 Quinoline derivatives 失效
标题翻译：喹啉衍生物
公开(公告)号：US07375227B2
公开(公告)日：2008-05-20
申请号：US10501054
申请日：2002-12-02
申请人： Hamed Aissaoui , Christoph Binkert , Martine Clozel , Boris Mathys , Claus Mueller , Oliver Nayler , Michael Scherz , Jörg Velker , Thomas Weller
发明人： Hamed Aissaoui , Christoph Binkert , Martine Clozel , Boris Mathys , Claus Mueller , Oliver Nayler , Michael Scherz , Jörg Velker , Thomas Weller
IPC分类号： C07D215/38 , C07D215/44
CPC分类号： C07D471/04 , C07D401/12 , C07D401/14
摘要： The invention relates to novel 1-pyridin-4-yl urea derivatives and related compounds and their use as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including processes for the preparation of the compounds, pharmaceutical compositions containing one or more of those compounds and especially their use as neurohormonal antagonists.
摘要翻译：本发明涉及新颖的1-吡啶-4-基脲衍生物及其相关化合物及其在制备药物组合物中作为活性成分的用途。本发明还涉及包括制备化合物的方法，含有一种或多种这些化合物的药物组合物，特别是其作为神经激素拮抗剂的用途的相关方面。

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