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1. 发明申请

US20080262324A1 Measurement Head For Non-Invasive Blood Analysis 失效
标题翻译：非侵入性血液分析测量头
公开(公告)号：US20080262324A1
公开(公告)日：2008-10-23
申请号：US11568743
申请日：2005-05-03
申请人： Marjolein Van Der Voort , Bernardus Leonardus Gerardus Bakker , Gerald Lucassen , Hendrikus Antonius Cornelus Maria Compen , Michael Cornelis Van Beek , Wouter Harry Jacinth Rensen
发明人： Marjolein Van Der Voort , Bernardus Leonardus Gerardus Bakker , Gerald Lucassen , Hendrikus Antonius Cornelus Maria Compen , Michael Cornelis Van Beek , Wouter Harry Jacinth Rensen
IPC分类号： A61B5/00
CPC分类号： A61B5/0059 , A61B5/0062 , A61B5/68 , A61B5/6843
摘要： The present invention provides an efficient approach of attaching and fixing a measurement head for a spectroscopic system to a variety of different parts of the skin of a patient. The measurement head preferably features a compact design providing a flexible handling and offering a huge variety of application areas taking into account the plurality of properties of various portions of the skin. Furthermore, the measurement head features a robust and uncomplicated optical design not requiring a lateral shifting of the optical axis of the objective. Such transverse relative movements between the objective and a capillary vessel in the skin are preferably performed by mechanically shifting the skin with respect to the objective of the measurement head. Moreover, the measurement head is adapted to host one or more pressure sensors measuring the contact pressure between the measurement head and the skin. This pressure information can further be exploited in order to calibrate the spectroscopic analysis means, to regulate the contact pressure within predefined margins specifying an optimum range of contact pressure for spectroscopic examination of capillary vessels.
摘要翻译：本发明提供了将用于分光系统的测量头附接和固定到患者皮肤的各种不同部分的有效方法。测量头优选地具有紧凑的设计，提供灵活的处理，并且考虑到皮肤的各个部分的多个性质，提供了各种各样的应用领域。此外，测量头具有坚固且不复杂的光学设计，不需要物镜的光轴的横向偏移。物体和皮肤中的毛细血管之间的这种横向相对移动优选通过相对于测量头的目标机械地移动皮肤来执行。此外，测量头适于承载测量测量头与皮肤之间的接触压力的一个或多个压力传感器。可以进一步利用该压力信息来校准光谱分析装置，以调节预定余量内的接触压力，从而规定用于毛细血管的光谱检查的最佳接触压力范围。

2. 发明授权

US08406835B2 Probe head for spectroscopic analysis of a fluid 失效
标题翻译：用于流体光谱分析的探头
公开(公告)号：US08406835B2
公开(公告)日：2013-03-26
申请号：US11568363
申请日：2005-02-14
申请人： Gerhardus Wilhelmus Lucassen , Wouter Harry Jacinth Rensen , Michael Cornelis Van Beek , Marjolein Van Der Voort , Bernardus Leonardus Gerardus Bakker
发明人： Gerhardus Wilhelmus Lucassen , Wouter Harry Jacinth Rensen , Michael Cornelis Van Beek , Marjolein Van Der Voort , Bernardus Leonardus Gerardus Bakker
IPC分类号： A61B5/1455 , A61B5/00 , G02B6/44
CPC分类号： A61B5/0059 , A61B5/489 , A61B2562/0242
摘要： A spectroscopic system for determining a property of a fluid flowing through a volume of interest underneath the surface of the skin of a patient is described. The spectroscopic system comprises: a probe head having an objective for directing an excitation beam into the volume of interest and for collecting return radiation from the volume of interest; a base station having a spectroscopic analysis unit and a power supply; and a cable connecting the probe head and the base station for transmission of the return radiation from the probe head to the base station and for providing the probe head with power from the power supply of the base station.
摘要翻译：描述了用于确定流过患者皮肤表面下方的感兴趣体积的流体的性质的光谱系统。分光系统包括：探头，其具有用于将激发光束引导到感兴趣体积中并用于从感兴趣体积收集返回辐射的目标; 具有光谱分析单元和电源的基站; 以及连接探头和基站的电缆，用于将返回辐射从探头传输到基站，并为探头提供来自基站的电源的电力。

3. 发明授权

US07817268B2 Alignment system for spectroscopic analysis 失效
标题翻译：光谱分析校准系统
公开(公告)号：US07817268B2
公开(公告)日：2010-10-19
申请号：US11574161
申请日：2005-08-24
申请人： Bernardus Leonardus Gerardus Bakker , Michael Cornelis Van Beek , Gérald Lucassen , Marjolein Van Der Voort , Wouter Harry Jacinth Rensen
发明人： Bernardus Leonardus Gerardus Bakker , Michael Cornelis Van Beek , Gérald Lucassen , Marjolein Van Der Voort , Wouter Harry Jacinth Rensen
IPC分类号： G01J3/30
CPC分类号： G01J3/02 , G01J1/4228 , G01J3/0229 , G01J3/0289
摘要： The present invention provides a spectroscopic system as well as a method of autonomous tuning of a spectroscopic system and a corresponding computer program product. By detecting the position of return radiation in a transverse plane of an aperture of a spectroscopic analysis unit, a control signal can be generated that allows to drive servo driven translation or tilting stages of optical components. In this way a transverse misalignment of a spectroscopic system can be effectively detected. Generally, a plurality of different detection schemes are realizable allowing for an autonomous tuning of the spectroscopic system and for autonomous elimination of misalignment of a spectroscopic system.
摘要翻译：本发明提供一种光谱系统以及自动调谐光谱系统和相应的计算机程序产品的方法。通过检测光谱分析单元的孔径的横向平面中的返回辐射的位置，可以产生允许驱动光学部件的伺服驱动的平移或倾斜级的控制信号。以这种方式，可以有效地检测光谱系统的横向偏移。通常，多个不同的检测方案是可实现的，允许分光系统的自主调谐并且用于自动消除光谱系统的未对准。

4. 发明授权

US07557916B2 Spectroscopic system with multiple probes 失效
标题翻译：具有多个探针的光谱系统
公开(公告)号：US07557916B2
公开(公告)日：2009-07-07
申请号：US11570137
申请日：2005-06-22
申请人： Bernardus Leonardus Gerardus Bakker , Michael Cornelis Van Beek
发明人： Bernardus Leonardus Gerardus Bakker , Michael Cornelis Van Beek
IPC分类号： G01J3/30
CPC分类号： G01N21/65 , G01N2021/653 , G01N2021/655
摘要： The present invention provides a spectroscopic system for non invasive spectral analysis of substances or biological structures (114, 116) that are located in a plurality of various volumes of interest (110, 112). The inventive spectroscopic system makes use of a multiplicity of various probe heads (106, 108) that are connected to a base station (100) providing a spectroscopic light source (104) and spectroscopic analysis means (102) . By additionally implementing a coupling unit (132) the present invention allows to realize a spectroscopic analysis environment that makes spectroscopic analysis available in a variety of different locations, e.g. various rooms of a hospital.
摘要翻译：本发明提供了一种用于对位于多个不同感兴趣体积（110,112）中的物质或生物结构（114,116）进行无创光谱分析的光谱系统。本发明的光谱系统利用连接到提供分光光源（104）的基站（100）和光谱分析装置（102）的多个各种探头（106,108）。通过附加地实现耦合单元（132），本发明允许实现使得光谱分析在各种不同位置（例如，一间医院的各种房间。

5. 发明申请

US20080129991A1 Alignment System for Spectroscopic Analysis 失效
标题翻译：光谱分析校准系统
公开(公告)号：US20080129991A1
公开(公告)日：2008-06-05
申请号：US11574161
申请日：2005-08-24
申请人： Bernardus Leonardus Gerardus Bakker , Michael Cornelis Van Beek , Gerald Lucassen , Marjolein Van Der Voort , Wouter Harry Jacinth Rensen
发明人： Bernardus Leonardus Gerardus Bakker , Michael Cornelis Van Beek , Gerald Lucassen , Marjolein Van Der Voort , Wouter Harry Jacinth Rensen
IPC分类号： G01J3/44
CPC分类号： G01J3/02 , G01J1/4228 , G01J3/0229 , G01J3/0289
摘要： The present invention provides a spectroscopic system as well as a method of autonomous tuning of a spectroscopic system and a corresponding computer program product. By detecting the position of return radiation in a transverse plane of an aperture of a spectroscopic analysis unit, a control signal can be generated that allows to drive servo driven translation or tilting stages of optical components. In this way a transverse misalignment of a spectroscopic system can be effectively detected. Generally, a plurality of different detection schemes are realizable allowing for an autonomous, tuning of the spectroscopic system and for autonomous elimination of misalignment of a spectroscopic system.
摘要翻译：本发明提供一种光谱系统以及自动调谐光谱系统和相应的计算机程序产品的方法。通过检测光谱分析单元的孔径的横向平面中的返回辐射的位置，可以产生允许驱动光学部件的伺服驱动的平移或倾斜级的控制信号。以这种方式，可以有效地检测光谱系统的横向偏移。通常，多个不同的检测方案是可实现的，允许对分光系统进行自主调谐，并自动消除光谱系统的未对准。

6. 发明授权

US07511812B2 Aberration correction for spectroscopic analysis 有权
标题翻译：光谱分析的畸变校正
公开(公告)号：US07511812B2
公开(公告)日：2009-03-31
申请号：US11570133
申请日：2005-06-13
申请人： Michael Cornelis Van Beek , Wouter Rensen , Gerald Lucassen , Marjolein Van Der Voort , Bernardus Leonardus Gerardus Bakker
发明人： Michael Cornelis Van Beek , Wouter Rensen , Gerald Lucassen , Marjolein Van Der Voort , Bernardus Leonardus Gerardus Bakker
IPC分类号： G01J3/30
CPC分类号： G02B27/0025 , G01J3/02 , G01J3/0208 , G01J3/021 , G01J3/28
摘要： A spectroscopic system which determines a property of a biological structure in a volume of interest of a person includes a low cost objective lens for directing an excitation beam into a volume of interest and for collecting return radiation from the volume of interest. After detection of the return radiation and generation of spectroscopic signals, a correction unit performs a compensation for aberrations of the spectroscopic signals introduced by the low cost objective lens. Since the aberrations of the objective lens strongly depend on the lateral distance of the volume of interest from the optical axis of the objective lens, the correction unit uses a correction table providing an assignment between correction values and various lateral positions of the volume of interest.
摘要翻译：确定人的感兴趣体积的生物结构的性质的光谱系统包括用于将激发光束引导到感兴趣体积中并用于从感兴趣体积收集返回辐射的低成本物镜。在检测到返回辐射和产生分光信号之后，校正单元对由低成本物镜引入的分光信号的像差进行补偿。由于物镜的像差强烈地取决于物镜的光轴的感兴趣的体积的横向距离，所以校正单元使用校正表，该校正表提供校正值与感兴趣体积的各个横向位置之间的分配。

7. 发明申请

US20080062401A1 Spectroscopic System With Multiple Probes 失效
标题翻译：多探针光谱系统
公开(公告)号：US20080062401A1
公开(公告)日：2008-03-13
申请号：US11570137
申请日：2005-06-22
申请人： Bernardus Leonardus Gerardus Bakker , Michael Cornelis Van Beek
发明人： Bernardus Leonardus Gerardus Bakker , Michael Cornelis Van Beek
IPC分类号： G01N21/25 , G02B6/42 , G06F19/00
CPC分类号： G01N21/65 , G01N2021/653 , G01N2021/655
摘要： The present invention provides a spectroscopic system for non invasive spectral analysis of substances or biological structures (114, 116) that are located in a plurality of various volumes of interest (110, 112). The inventive spectroscopic system makes use of a multiplicity of various probe heads (106, 108) that are connected to a base station (100) providing a spectroscopic light source (104) and spectroscopic analysis means (102) . By additionally implementing a coupling unit (132) the present invention allows to realize a spectroscopic analysis environment that makes spectroscopic analysis available in a variety of different locations, e.g. various rooms of a hospital.
摘要翻译：本发明提供了一种用于对位于多个不同感兴趣体积（110,112）中的物质或生物结构（114,116）进行无创光谱分析的光谱系统。本发明的光谱系统利用连接到提供分光光源（104）的基站（100）和光谱分析装置（102）的多个各种探头（106,108）。通过附加地实现耦合单元（132），本发明允许实现使得光谱分析在各种不同位置（例如，一间医院的各种房间。

8. 发明申请

US20080215038A1 Hair Removing System 有权
标题翻译：脱毛系统
公开(公告)号：US20080215038A1
公开(公告)日：2008-09-04
申请号：US11996318
申请日：2006-07-21
申请人： Bernardus Leonardus Gerardus Bakker , Robbert Adrianus Maria Van Hal , Rieko Verhagen
发明人： Bernardus Leonardus Gerardus Bakker , Robbert Adrianus Maria Van Hal , Rieko Verhagen
IPC分类号： A61B18/18 , A61B17/50 , A61B19/00
CPC分类号： A61B18/203 , A61B18/20 , A61B2018/00452 , A61B2018/00476 , A61B2018/00904
摘要： The invention relates to a system and method for removing hair The system comprises a hair detection device and a hair-removing device (20). Since 3D information on hairs (32) is required, but due to the very dispersed presence of, e.g., human hairs (32) on skin (30), known detection devices are too slow, the invention provides a combination of two image sensors. A first image sensor (12) produces a first image, based on which a selected part is imaged with a second image sensor (14) that provides the required 3D position information with which the hair-removing device (20) can remove the hair Thus, optimum use may be made of both fast but less accurate image sensors, such as (2D) CCDs or CMOS sensors, and accurate but slow sensors such as 3D scanning sensors.
摘要翻译：本发明涉及一种用于去毛发的系统和方法。该系统包括毛发检测装置和脱毛装置（20）。由于需要关于毛发（32）的3D信息，而是由于例如皮肤（30）上的人类毛发（32）的非常分散的存在，已知的检测装置太慢，本发明提供了两个图像传感器的组合。第一图像传感器（12）产生第一图像，基于该第一图像，通过第二图像传感器（14）对所选择的部分进行成像，第二图像传感器提供所需的3D位置信息，毛发去除装置（20）可以通过该位置信息去除头发。因此，可以最佳地使用诸如（2D）CCD或CMOS传感器的快速但不精确的图像传感器，以及诸如3D扫描传感器的精确但缓慢的传感器。

9. 发明授权

US07517344B2 Device for treating human skin by means of radiation 有权
标题翻译：用于通过辐射处理人体皮肤的装置
公开(公告)号：US07517344B2
公开(公告)日：2009-04-14
申请号：US10536242
申请日：2003-10-31
申请人： Robbert Adrianus Maria Van Hal , Bernardus Leonardus Gerardus Bakker , Paul Anton Josef Ackermans
发明人： Robbert Adrianus Maria Van Hal , Bernardus Leonardus Gerardus Bakker , Paul Anton Josef Ackermans
IPC分类号： A61B18/18
CPC分类号： A61B18/203 , A61B2018/00005 , A61B2018/00452 , A61B2018/1807
摘要： The invention relates to a device (1) for treating human skin by means of radiation. The device comprises a housing (3) with a radiation exit opening (13). A radiation source (9) is accommodated in the housing. Radiation generated by the radiation source propagates from the radiation source towards the radiation exit opening via a radiation path (15) comprising a radiation filter having a predetermined transmission spectrum. According to the invention the radiation filter comprises a reflecting surface (23) via which the radiation propagating along the radiation path (15) is reflected. The reflecting surface has a coating which provides the reflecting surface with a reflection spectrum substantially matching the predetermined transmission spectrum. An advantage is that the reflection surface can be optimally and uniformly cooled, so that the heat generated as a result of the absorption of part of the radiation by the radiation filter can be effectively transmitted to a cooling system (25) of the device (1). In a particular embodiment the device (1) is an epilator for removing hairs from the human skin and the radiation source (9) is a flash lamp. The radiation path (15) is enclosed by a channel (17) having a bend (19) and having an inner wall (21) on which the reflecting surface (23) is provided.
摘要翻译：本发明涉及一种用于通过辐射处理人体皮肤的装置（1）。该装置包括具有辐射出口（13）的壳体（3）。辐射源（9）容纳在壳体中。由辐射源产生的辐射经由包括具有预定透射光谱的辐射滤光片的辐射路径（15）从辐射源向辐射出口开口传播。根据本发明，辐射过滤器包括反射表面（23），沿着辐射路径（15）传播的辐射被反射。反射面具有使反射面具有基本上与预定透射光谱相一致的反射光谱的涂层。优点在于反射面可以被最佳和均匀地冷却，使得由辐射过滤器吸收一部分辐射而产生的热能被有效地传递到装置（1）的冷却系统（25））。在特定实施例中，装置（1）是用于从人体皮肤去除头发的脱毛器，并且辐射源（9）是闪光灯。辐射路径（15）由具有弯曲部（19）的通道（17）包围，并具有设置有反射面（23）的内壁（21）。

10. 发明授权

US09283038B2 Hair removing system 有权
标题翻译：脱毛系统
公开(公告)号：US09283038B2
公开(公告)日：2016-03-15
申请号：US11996318
申请日：2006-07-21
申请人： Bernardus Leonardus Gerardus Bakker , Robbert Adrianus Maria Van Hal , Rieko Verhagen
发明人： Bernardus Leonardus Gerardus Bakker , Robbert Adrianus Maria Van Hal , Rieko Verhagen
IPC分类号： A61B18/20 , A61B18/00
CPC分类号： A61B18/203 , A61B18/20 , A61B2018/00452 , A61B2018/00476 , A61B2018/00904
摘要： The invention relates to a system and method for removing hair. The system comprises a hair detection device and a hair-removing device (20). Since 3D information on hairs (32) is required, but due to the very dispersed presence of, e.g., human hairs (32) on skin (30), known detection devices are too slow, the invention provides a combination of two image sensors. A first image sensor (12) produces a first image, based on which a selected part is imaged with a second image sensor (14) that provides the required 3D position information with which the hair-removing device (20) can remove the hair. Thus, optimum use may be made of both fast but less accurate image sensors, such as (2D) CCDs or CMOS sensors, and accurate but slow sensors such as 3D scanning sensors.
摘要翻译：本发明涉及一种去除毛发的系统和方法。该系统包括毛发检测装置和脱毛装置（20）。由于需要关于毛发（32）的3D信息，而是由于例如皮肤（30）上的人类毛发（32）的非常分散的存在，已知的检测装置太慢，本发明提供了两个图像传感器的组合。第一图像传感器（12）产生第一图像，基于该第一图像，通过第二图像传感器（14）对所选择的部分进行成像，第二图像传感器提供所需的3D位置信息，毛发去除装置（20）可以通过该位置信息去除头发。因此，可以最佳地使用诸如（2D）CCD或CMOS传感器的快速但不精确的图像传感器，以及诸如3D扫描传感器的精确但缓慢的传感器。

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