专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

US20060223131A1 Protein arrays and methods of use thereof 审中-公开
标题翻译：蛋白质阵列及其使用方法
公开(公告)号：US20060223131A1
公开(公告)日：2006-10-05
申请号：US11229258
申请日：2005-09-15
申请人： Barry Schweitzer , James Ball , Paul Predki , Fang Zhou , Gregory Michaud
发明人： Barry Schweitzer , James Ball , Paul Predki , Fang Zhou , Gregory Michaud
IPC分类号： G01N33/53 , G06Q10/00 , C12M1/34
CPC分类号： C12Q1/00 , B01J2219/00387 , B01J2219/00497 , B01J2219/00527 , B01J2219/00585 , B01J2219/00596 , B01J2219/00605 , B01J2219/0061 , B01J2219/00612 , B01J2219/00626 , B01J2219/0063 , B01J2219/00637 , B01J2219/00641 , B01J2219/00659 , B01J2219/00693 , B01J2219/00725 , G01N33/552 , G01N33/6842 , G01N33/6845 , G06Q50/22 , Y02A90/22
摘要： The present invention provides human protein arrays that include at least 1000 human proteins. In another embodiment, the present invention provides a method for identifying a substrate of an enzyme, comprising contacting the enzyme with a positionally addressable array comprising at least 100 proteins immobilized on functionalized glass surface, and identifying a protein on the positionally addressable array that is bound and/or modified by the enzyme, wherein a binding or modifying of the protein by the enzyme indicates that the protein is a substrate for the enzyme. In additional embodiments, provided herein are methods for making an array of at least 1000 human proteins under non-denaturing conditions, including human proteins that are difficult to express and/or difficult to isolate in a non-denatured state.
摘要翻译：本发明提供了包含至少1000种人蛋白质的人类蛋白质阵列。在另一个实施方案中，本发明提供了一种用于鉴定酶底物的方法，包括使酶与包含至少100个固定在官能化玻璃表面上的蛋白质的位置可寻址阵列接触，以及鉴定结合位置可寻址阵列上的蛋白质和/或由酶修饰，其中酶的蛋白质的结合或修饰表明蛋白质是酶的底物。在另外的实施方案中，本文提供了在非变性条件下制备至少1000种人类蛋白质的阵列的方法，包括在非变性状态下难以表达和/或难以分离的人类蛋白质。

2. 发明申请

US20110034350A1 Protein Arrays and Methods of Use Thereof 审中-公开
标题翻译：蛋白质阵列及其使用方法
公开(公告)号：US20110034350A1
公开(公告)日：2011-02-10
申请号：US12768198
申请日：2010-04-27
申请人： Barry Schweitzer , James Ball , Paul F. Predki , Fang X. Zhou , Gregory A. Michaud
发明人： Barry Schweitzer , James Ball , Paul F. Predki , Fang X. Zhou , Gregory A. Michaud
IPC分类号： C40B50/06
CPC分类号： C12Q1/00 , B01J2219/00387 , B01J2219/00497 , B01J2219/00527 , B01J2219/00585 , B01J2219/00596 , B01J2219/00605 , B01J2219/0061 , B01J2219/00612 , B01J2219/00626 , B01J2219/0063 , B01J2219/00637 , B01J2219/00641 , B01J2219/00659 , B01J2219/00693 , B01J2219/00725 , G01N33/552 , G01N33/6842 , G01N33/6845 , G06Q50/22 , Y02A90/22
摘要： The present invention provides human protein arrays that include at least 1000 human proteins. In another embodiment, the present invention provides a method for identifying a substrate of an enzyme, comprising contacting the enzyme with a positionally addressable array comprising at least 100 proteins immobilized on functionalized glass surface, and identifying a protein on the positionally addressable array that is bound and/or modified by the enzyme, wherein a binding or modifying of the protein by the enzyme indicates that the protein is a substrate for the enzyme. In additional embodiments, provided herein are methods for making an array of at least 1000 human proteins under non-denaturing conditions, including human proteins that are difficult to express and/or difficult to isolate in a non-denatured state.
摘要翻译：本发明提供了包含至少1000种人蛋白质的人类蛋白质阵列。在另一个实施方案中，本发明提供了一种用于鉴定酶底物的方法，包括使酶与包含至少100个固定在官能化玻璃表面上的蛋白质的位置可寻址阵列接触，以及鉴定结合位置可寻址阵列上的蛋白质和/或由酶修饰，其中酶的蛋白质的结合或修饰表明蛋白质是酶的底物。在另外的实施方案中，本文提供了在非变性条件下制备至少1000种人类蛋白质的阵列的方法，包括在非变性状态下难以表达和/或难以分离的人类蛋白质。

3. 发明申请

US20070060797A1 Automatic parameter status on an implantable medical device system 有权
标题翻译：可植入医疗设备系统上的自动参数状态
公开(公告)号：US20070060797A1
公开(公告)日：2007-03-15
申请号：US11217028
申请日：2005-08-31
申请人： James Ball , Sean McAdams , Chris House
发明人： James Ball , Sean McAdams , Chris House
IPC分类号： A61B5/00 , A61B5/05 , A61N1/00
CPC分类号： A61N1/37252 , A61B5/0002 , A61B5/0031 , A61B5/4875 , A61B5/686 , A61B5/6869 , A61B5/746 , A61N1/36 , A61N1/3702 , G06F19/00 , G06F19/34 , G06F19/3418 , G08B21/0211 , G16H40/40
摘要： A method and apparatus for providing status of a parameter that includes detecting an alert level of a parameter monitored by an implanted medical device, transmitting data corresponding to the detected alert level from the implanted medical device to an external monitor, scheduling a follow-up interrogation session after receiving transmitted data corresponding to the detected alert level, and retrieving updated data from the implanted medical device corresponding to the monitored parameter during the follow-up interrogation session.
摘要翻译：一种用于提供参数状态的方法和装置，包括检测由植入的医疗设备监测的参数的警报级别，将与检测到的警报级别相对应的数据从植入的医疗设备发送到外部监视器，调度后续询问在接收到与检测到的警报级别相对应的发送数据之后，会话，以及在后续询问会话期间从与所监视的参数相对应的植入的医疗设备检索更新的数据。

4. 发明申请

US20060245951A1 Multilayer valve structures, methods of making, and pumps using same 审中-公开
标题翻译：多层阀结构，制造方法和使用相同的泵
公开(公告)号：US20060245951A1
公开(公告)日：2006-11-02
申请号：US11104661
申请日：2005-04-13
申请人： James Ball
发明人： James Ball
IPC分类号： F04B17/00
CPC分类号： F04B53/1037 , F04B53/1087
摘要： A multilayer valve subassembly (50) comprises an interface layer (60) having an interface layer flap (62, 64); a cover layer (70) having a cover layer flap (72, 74); and, an intermediate layer (80) positioned between the interface layer and the cover layer. The intermediate layer (80) has an intermediate layer flap (82, 84) essentially aligned with the interface layer flap and the cover layer flap. A first bond (102) adheres the cover layer (70) to the interface layer (60); a flap bond (92, 94) seals the interface layer flap (82, 84) between the cover layer flap (72, 74) and the interface layer flap (62, 64) and thereby forms a multilayer valve flap (52, 54) which is insulated from fluid which travels through the valve. In an example embodiment, the each of the interface layer flap, the cover layer flap, and the interface layer flap has a substantially U-shape. Preferably the interface layer is not in contact with the first bond or the second bond and has a size that permits the interface layer to float in a sandwich pocket formed between the interface layer and the cover layer.
摘要翻译：多层阀子组件（50）包括具有界面层翼片（62,64）的界面层（60）; 具有覆盖层翼片（72,74）的覆盖层（70）; 以及位于界面层和覆盖层之间的中间层（80）。中间层（80）具有基本上与界面层翼片和覆盖层翼片对准的中间层翼片（82,84）。第一接合（102）将覆盖层（70）粘合到界面层（60）上; 翼片接合（92,94）密封覆盖层翼片（72,74）和界面层翼片（62,64）之间的界面层翼片（82,84），从而形成多层瓣膜（52,54）其与穿过阀门的流体绝缘。在示例性实施例中，界面层翼片，覆盖层翼片和界面层翼片中的每一个具有大致U形。优选地，界面层不与第一接合或第二接合接触，并且具有允许界面层漂浮在形成在界面层和覆盖层之间的夹层袋中的尺寸。

5. 发明授权

US4687040A Adjusting device for a slat blind 失效
标题翻译：平板盲板调整装置
公开(公告)号：US4687040A
公开(公告)日：1987-08-18
申请号：US840643
申请日：1986-03-17
申请人： James Ball
发明人： James Ball
IPC分类号： E06B9/264 , E06B9/32 , E06B3/32
CPC分类号： E06B9/32 , E06B9/264 , E06B2009/2646
摘要： A mechanism for adjusting the tilt angle of slats of a slat blind positioned between the panes of glass of a sealed window unit is described. The mechanism is sealed about an aperture through one of the panes and includes a flexible cable within a flexible tube extending from the mechanism to the control mechanism for the blind. The flexible tube maintains the window seal and the cable enables torque to be transmitted from the mechanism to the tilt control mechanism of the blind, thereby allowing direct external mechanical control of the tilt angle of the slats without breaking the hermetic seal for the window.
摘要翻译：描述了一种用于调节位于密封窗单元的玻璃板之间的板条盲板的倾斜角度的机构。机构通过一个窗格围绕孔密封，并且在柔性管内包括柔性电缆，柔性管从机构延伸到盲人的控制机构。柔性管保持窗口密封，并且电缆使扭矩能够从机构传递到盲板的倾斜控制机构，从而允许对板条的倾斜角的直接外部机械控制，而不破坏窗户的气密密封。

6. 发明申请

US20110318820A1 Immobilized Buffer Particles and Uses Thereof 审中-公开
标题翻译：固定缓冲颗粒及其用途
公开(公告)号：US20110318820A1
公开(公告)日：2011-12-29
申请号：US13172048
申请日：2011-06-29
申请人： Wolfgang Hinz , David Light , Todd Rearick , James Ball
发明人： Wolfgang Hinz , David Light , Todd Rearick , James Ball
IPC分类号： C12M1/34
CPC分类号： C12Q1/6874 , G01N27/4145
摘要： The disclosure relates to novel particle compositions and methods of making said compositions having applications in nucleic acid analysis, as well as apparatuses and systems for the same.
摘要翻译：本公开涉及新型颗粒组合物和制备所述组合物在核酸分析中的应用的方法，以及用于其的装置和系统。

7. 发明申请

US20070250130A1 Remote Communication System with Availability Indicator for an Implantable Medical Device 有权
标题翻译：具有可植入医疗设备可用性指示器的远程通信系统
公开(公告)号：US20070250130A1
公开(公告)日：2007-10-25
申请号：US11380139
申请日：2006-04-25
申请人： James Ball , Robert Ryan
发明人： James Ball , Robert Ryan
IPC分类号： A61N1/00
CPC分类号： A61N1/37282
摘要： A medical information communication system and corresponding methods are described. The system can permit monitoring the performance of an implantable medical device (IMD) implanted within a body of a patient, monitoring the health of the patient, and/or remotely delivering a therapy to the patient through the IMD. The IMD can be capable of bidirectional communication with a clinician. Further, the system can comprise a communication availability indicator to indicate whether the IMD is available for communication.
摘要翻译：描述医疗信息通信系统及相应的方法。该系统可以允许监测植入在患者身体内的可植入医疗装置（IMD）的性能，监测患者的健康，和/或通过IMD远程地向患者传递治疗。 IMD能够与临床医生进行双向通信。此外，系统可以包括用于指示IMD是否可用于通信的通信可用性指示符。

8. 发明授权

US06270706B1 Methods of forming or treating an article or preform 失效
标题翻译：形成或处理制品或预成型件的方法
公开(公告)号：US06270706B1
公开(公告)日：2001-08-07
申请号：US09065519
申请日：1998-04-24
申请人： James Ball
发明人： James Ball
IPC分类号： D01D109
CPC分类号： E04C3/29
摘要： A method of forming or treating an article or preform (10) and an article or preform made according to the method are provided. The method includes the step of providing around at least part of the article or preform (10) a generally tubular element (14) whose effective cross-section tends to reduce on extension, and applying an extension load to the tubular element (14) thereby to apply a compression load to the exterior of the article or preform to aid consolidation thereof.
摘要翻译：提供了一种形成或处理根据该方法制造的制品或预成型件（10）和制品或预制件的方法。该方法包括提供物品或预成型件（10）的至少一部分的大致管状元件（14）的步骤，其有效横截面在延伸时倾向于减小，并且将延伸载荷施加到管状元件（14），从而将压缩载荷施加到制品或预成型件的外部以辅助其固结。

9. 发明申请

US20060017576A1 Alert system and method for an implantable medical device 有权
标题翻译：可植入医疗器械的警戒系统和方法
公开(公告)号：US20060017576A1
公开(公告)日：2006-01-26
申请号：US10977242
申请日：2004-10-29
申请人： Paul Gordon , Javaid Masoud , James Ball , Holly Vitense , James Willenbring , John Vandnacker , Sean McAdams , Dean Hooper
发明人： Paul Gordon , Javaid Masoud , James Ball , Holly Vitense , James Willenbring , John Vandnacker , Sean McAdams , Dean Hooper
IPC分类号： G08B23/00
CPC分类号： A61N1/37282 , A61B5/0031 , A61B5/746 , A61N1/37247 , A61N1/37258 , G06F19/00 , G06F19/3418 , G06Q50/22 , G06Q50/24 , G16H40/63 , Y10S707/99939
摘要： An alert system for alerting a clinician to an occurrence of an event detected by an implantable medical device includes a monitor and a patient management network. The implantable medical device includes a means for detecting the occurrence of the event and initiating a wireless transmission of data related to the event. The monitor is configured to receive the wireless transmission of data and transfer the data. The patient management network is configured to receive the data and store the data on a data storage device. The patient management network includes a web presentation service for creating a website from the data stored on the data storage device, the website configured to alert the clinician to the occurrence of the event.
摘要翻译：用于警告临床医生发生由可植入医疗装置检测到的事件的警报系统包括监视器和患者管理网络。可植入医疗装置包括用于检测事件的发生和发起与事件有关的数据的无线传输的装置。监视器被配置为接收数据的无线传输并传送数据。患者管理网络被配置为接收数据并将数据存储在数据存储设备上。患者管理网络包括用于从存储在数据存储设备上的数据创建网站的网络呈现服务，网站被配置为警告临床医生发生事件。

10. 发明申请

US20060231238A1 Integrated thermal exchange systems and methods of fabricating same 审中-公开
标题翻译：集成热交换系统及其制造方法
公开(公告)号：US20060231238A1
公开(公告)日：2006-10-19
申请号：US11104668
申请日：2005-04-13
申请人： James Ball
发明人： James Ball
IPC分类号： H05K7/20
CPC分类号： G06F1/20 , F28D1/0325 , F28D1/0408 , F28D15/00 , F28D2021/0031 , F28F3/02 , F28F2270/00 , H01L23/467 , H01L23/473 , H01L2924/0002 , H01L2924/00
摘要： Thermal exchange systems integrate a thermal transfer unit (22); a fluid cooling assembly (24); a pump (26); and a fan (28). The thermal transfer unit (22) interfaces with a body to be thermally conditioned and transfers thermal energy to a fluid. The fluid cooling assembly (24) cools the fluid obtained from the thermal transfer unit. The fan (28) directs air around the fluid cooling assembly (24). The pump (26) circulates fluid in a circuit comprising the pump (26), the fluid cooling assembly (2), and the thermal transfer unit (22). In one aspect of integrated system technology, the fan (28) and the circuit are compactly arranged and substantially situated entirely within a footprint (33) of a module housing (30). As another technological aspect, the fluid cooling assembly (24) comprises plural thermal dissipation plates (45) which are laminated together. In an example, non-limiting mode, the plural thermal dissipation plates (45) have features formed thereon by etching or stamping. Such features which may be etched or stamped can include one or more of an aperture (53/64) for defining a fluid inlet channel; a fluid return aperture (55); a thermal dissipation fin (67); a fluid return region (65) which is substantially surrounded by a lamination contact surface through which the thermal dissipation plate (45) is in contact with an adjacent thermal dissipation plate.
摘要翻译：热交换系统集成热转印单元（22）; 流体冷却组件（24）; 泵（26）; 和风扇（28）。热转印单元（22）与待热处理的主体相接触，并将热能传递给流体。流体冷却组件（24）冷却从热转印单元获得的流体。风扇（28）引导空气围绕流体冷却组件（24）。泵（26）在包括泵（26），流体冷却组件（2）和热转印单元（22）的回路中循环流体。在集成系统技术的一个方面，风扇（28）和电路紧凑地布置并且基本上完全位于模块壳体（30）的占地面积（33）内。作为另一技术方面，流体冷却组件（24）包括层叠在一起的多个散热板（45）。在非限制模式的示例中，多个散热板（45）具有通过蚀刻或冲压在其上形成的特征。可以蚀刻或冲压的这些特征可以包括用于限定流体入口通道的孔（53/64）中的一个或多个; 流体返回孔（55）; 散热片（67）; 流体返回区域（65），其基本上被散热板（45）与相邻的散热板接触的层叠接触表面围绕。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式