专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

WO2011041680A3 COMPOSITIONS AND METHODS OF PROPHYLAXIS FOR CONTACT DERMATITIS 审中-公开
标题翻译：用于接触剂的丙烯酸酯的组合物和方法
公开(公告)号：WO2011041680A3
公开(公告)日：2011-08-18
申请号：PCT/US2010051125
申请日：2010-10-01
申请人： BRIGHAM & WOMENS HOSPITAL , GEN HOSPITAL CORP , KARP JEFFREY M , VEMULA PRAVEEN KUMAR , ANDERSON RICHARD ROX
发明人： KARP JEFFREY M , VEMULA PRAVEEN KUMAR , ANDERSON RICHARD ROX
IPC分类号： A61K9/00 , A61K9/06 , A61K9/50 , A61K47/30 , A61K47/44 , A61P17/00
CPC分类号： A61K47/02 , A61K9/0014 , A61K47/10 , Y10T428/2982
摘要： The present invention relates to compositions and methods for inhibiting metal exposure to tissues.
摘要翻译：本发明涉及抑制金属暴露于组织的组合物和方法。

2. 发明申请

WO2008005402A3 DEVICE AND METHOD FOR WIDE- FIELD AND HIGH RESOLUTION IMAGING OF TISSUE 审中-公开
标题翻译：用于组织的宽场和高分辨率成像的装置和方法
公开(公告)号：WO2008005402A3
公开(公告)日：2008-04-10
申请号：PCT/US2007015277
申请日：2007-06-29
申请人： GEN HOSPITAL CORP , YAROSLAVSKY ANNA M , WEBB ROBERT H , ANDERSON RICHARD ROX
发明人： YAROSLAVSKY ANNA N , WEBB ROBERT H , ANDERSON RICHARD ROX
IPC分类号： A61B8/14
CPC分类号： G02B21/0024 , A61B5/0068 , A61B5/0071 , A61B5/444
摘要： A device for wide-field and high resolution imaging of an object surface includes first and second imaging modalities, a lens associated with the second imaging modality. The first imaging modality has a high resolution imaging means with a first observation line. The second imaging modality is arranged in an image plane at a first angle with respect to an object plane and has a second observation line and a wider imaging field than the first imaging modality. The lens associated with the second imaging modality is arranged in a lens plane at a second angle with respect to the object plane, where the second angle being equal to about one-half of the first angle. The first and second imaging modalities are mutually arranged such that the first and second optical axes intersect at a point on the object plane.
摘要翻译：一种用于对象表面的宽视野和高分辨率成像的设备包括第一成像模态和第二成像模态，与第二成像模态相关联的透镜。第一成像模式具有带有第一观察线的高分辨率成像装置。第二成像模态相对于物平面以第一角度布置在像平面中，并且具有比第一成像模态更宽的第二观察线和更宽的成像场。与第二成像模态相关联的透镜相对于物平面以第二角度布置在透镜平面中，其中第二角度等于第一角度的大约一半。第一成像模态和第二成像模态被相互布置为使得第一光轴和第二光轴在物平面上的点处相交。

3. 发明申请

WO2010017477A3 METHOD AND APPARATUS FOR DERMATOLOGICAL HYPOPIGMENTATION 审中-公开
标题翻译：用于血液透析的方法和装置
公开(公告)号：WO2010017477A3
公开(公告)日：2010-07-08
申请号：PCT/US2009053153
申请日：2009-08-07
申请人： GEN HOSPITAL CORP , ANDERSON RICHARD ROX , MANSTEIN DIETER
发明人： ANDERSON RICHARD ROX , MANSTEIN DIETER
IPC分类号： A61F7/00 , A61H39/04
CPC分类号： A61B18/0218 , A61B2017/00747 , A61B2018/00005 , A61B2018/00458 , A61B2018/0047 , A61B2018/00577 , A61B2018/00714 , A61B2018/00815 , A61B2018/00821 , A61B2018/0237 , A61B2018/0293 , A61B2018/143 , A61F7/00 , A61F7/0085 , A61F7/10 , A61F2007/0052 , A61F2007/0056 , A61F2007/0063 , A61F2007/0075 , A61F2007/0086 , A61F2007/0087 , A61F2007/0089 , A61F2007/0095 , A61F2007/0096 , A61F2007/0292
摘要： Exemplary embodiments of the present disclosure provide method and apparatus for effecting (e.g., lightening) an appearance of skin by cooling or freezing small separated surface regions of the skin to produce regions of local hypopigmentation. The width of the regions can be, for example, smaller than about 1 mm or 0.5 mm, and a distance between these frozen regions can be greater than about 3 times the width of the regions. An exemplary apparatus can be provided that includes a plurality of spatially-separated thermally conductive arrangements that can be affixed or otherwise coupled to a base. For example, the conductive arrangements can be regions of conductive material provided in or proximal to a thermal insulator, or thermally conductive protrusions affixed to the base. The conductive arrangements can be cooled and then contacted with the skin surface to produce the small regions of hypopigmentation.
摘要翻译：本公开的示例性实施方案提供了通过冷却或冷冻皮肤的小分离表面区域来实现（例如，减轻）皮肤外观的方法和装置，以产生局部色素沉着的区域。区域的宽度可以例如小于约1mm或0.5mm，并且这些冻结区域之间的距离可以大于区域宽度的约3倍。可以提供一种示例性装置，其包括可以固定或以其他方式耦合到基座的多个空间分离的导热装置。例如，导电布置可以是设置在绝热体中或靠近热绝缘体的导电材料区域，或者固定到基底的导热突起。导电布置可以被冷却，然后与皮肤表面接触以产生色素减少的小区域。

4. 发明申请

WO2007103721A3 SYSTEM AND METHOD FOR PROVIDING CELL SPECIFIC LASER THERAPY OF ATHEROSCLEROTIC PLAQUES BY TARGETING LIGHT ABSORBERS IN MACROPHAGES 审中-公开
标题翻译：用于通过将光吸收剂靶向在宏观物体中提供细胞特异性激光治疗动脉粥样硬化斑块的系统和方法
公开(公告)号：WO2007103721A3
公开(公告)日：2007-11-08
申请号：PCT/US2007063058
申请日：2007-03-01
申请人： GEN HOSPITAL CORP , NADKARNI SEEMANTINI K , TEARNEY GUILLERMO J , BOUMA BRETT E , VAKOC BENJAMIN J , ANDERSON RICHARD ROX
发明人： NADKARNI SEEMANTINI K , TEARNEY GUILLERMO J , BOUMA BRETT E , VAKOC BENJAMIN J , ANDERSON RICHARD ROX
IPC分类号： A61N5/06
CPC分类号： A61B18/245 , A61N5/0601 , A61N5/062
摘要： An apparatus and method according to the present invention can be provided, e.g., for a cell specific laser therapy of atherosclerotic plaques, particularly to systems and methods for targeting endogenous light absorbers present within plaque macrophages and exogenous nanoparticle targeting. In one exemplary embodiment, an electro-magnetic radiation can be forwarded to an anatomical structure. The electro-magnetic radiation may have at least one property configured to (a) modify at least one characteristic of at least one first cell, and (b) minimize any modification of and/or modify at least one characteristic of at least second cell. The first and second cells may be different from one another, the characteristics of the first and second cells can be different from one another, and the first cell and/or the second cell may have at least one macrophage feature, and the characteristic of the at least one first cell and/or the at least one second cell can be temperature. According to still another exemplary embodiment, a location associated with the first cell and the second cell can be determined. For example, the electro-magnetic radiation can be forwarded in a vicinity of the location.
摘要翻译：可以提供根据本发明的设备和方法，例如用于动脉粥样硬化斑块的细胞特异性激光治疗，特别是用于靶向存在于斑块巨噬细胞内的内源光吸收剂和外源纳米颗粒靶向的系统和方法。在一个示例性实施例中，电磁辐射可被转发至解剖结构。电磁辐射可以具有至少一种性质，其被配置为（a）修改至少一个第一电池的至少一个特性，并且（b）最小化至少第二电池的任何修改和/或修改至少一个特性。第一和第二细胞可以彼此不同，第一和第二细胞的特征可以彼此不同，并且第一细胞和/或第二细胞可以具有至少一个巨噬细胞特征，并且第一和第二细胞的特征至少一个第一电池和/或至少一个第二电池可以是温度。根据又一示例性实施例，可以确定与第一小区和第二小区相关联的位置。例如，可以在该位置附近发送电磁辐射。

5. 发明申请

WO2005046620A3 VARIABLE APPEARANCE TISSUE MARKINGS 审中-公开
标题翻译：可变外观组织标记
公开(公告)号：WO2005046620A3
公开(公告)日：2006-08-03
申请号：PCT/US2004038484
申请日：2004-11-12
申请人： GEN HOSPITAL CORP , FREEDOM 2 LLC , ANDERSON RICHARD ROX , MLYNARCZYK-EVANS SUSANNA K , DRILL CRAIG A
发明人： ANDERSON RICHARD ROX , MLYNARCZYK-EVANS SUSANNA K , DRILL CRAIG A
IPC分类号： B01D39/18 , A61F13/00 , A61K20060101 , C09D1/00 , C09D4/00 , C09D5/00 , C09D11/00
CPC分类号： C09D11/50
摘要： The present invention provides particles that create permanent tissue marking, including, but not limited to, tattoos, that have variable appearance properties. Also, the present invention provides methods for producing, implanting altering and removing these variable appearance tissue markings.
摘要翻译：本发明提供了产生永久性组织标记的颗粒，其包括但不限于具有可变外观性质的纹身。此外，本发明提供了用于制造，植入改变和去除这些可变外观组织标记的方法。

6. 发明申请

WO2005046576A2 MAGNETIC INK TISSUE MARKINGS 审中-公开
标题翻译：磁性墨水组织标记
公开(公告)号：WO2005046576A2
公开(公告)日：2005-05-26
申请号：PCT/US2004025585
申请日：2004-08-06
申请人： GEN HOSPITAL CORP , ANDERSON RICHARD ROX , KHAN MISBAH H
发明人： ANDERSON RICHARD ROX , KHAN MISBAH H
IPC分类号： C09D11/02 , H01F1/44 , A61K
CPC分类号： C09D11/02 , H01F1/445
摘要： The invention provides tissue markings (such as tattoos) comprising particles, e.g., magnetite, and methods for making and altering, e.g., removing them.
摘要翻译：本发明提供了包括颗粒的组织标记（例如纹身），例如磁铁矿，以及用于制造和改变例如去除它们的方法。

7. 发明申请

WO03078596A2 METHODS AND DEVICES FOR SELECTIVE DISRUPTION OF FATTY TISSUE BY CONTROLLED COOLING 审中-公开
标题翻译：通过控制冷却选择性破坏脂肪组织的方法和装置
公开(公告)号：WO03078596A2
公开(公告)日：2003-09-25
申请号：PCT/US0308014
申请日：2003-03-17
申请人： GEN HOSPITAL CORP , ANDERSON RICHARD ROX , MANSTEIN DIETER
发明人： ANDERSON RICHARD ROX , MANSTEIN DIETER
IPC分类号： C12N5/06 , A61B18/02 , A61F7/00 , A61F7/10 , A61H23/02 , C12N
CPC分类号： A61F7/00 , A61B5/415 , A61B5/6804 , A61B18/02 , A61B2018/0237 , A61B2018/0262 , A61F7/10 , A61F2007/0054 , A61F2007/0056 , A61F2007/0075 , A61F2007/0082 , A61F2007/0094 , A61F2007/0096 , A61F2007/0239 , A61F2007/029 , A61H23/00
摘要： The present invention relates to methods for use in the selective disruption of lipid-rich cells by controlled cooling. The present invention further relates to a device for use in carrying out the methods for selective disruption of lipid-rich cells by controlled cooling.
摘要翻译：本发明涉及用于通过受控冷却选择性破坏富含脂质细胞的方法。本发明还涉及一种用于实施通过受控冷却选择性破坏富含脂质细胞的方法的装置。

8. 发明申请

WO2007047726A3 NON-INVASIVE TREATMENT OF FASCIA 审中-公开
标题翻译：非侵入性处理的FASCIA
公开(公告)号：WO2007047726A3
公开(公告)日：2007-08-02
申请号：PCT/US2006040641
申请日：2006-10-18
申请人： GEN HOSPITAL CORP , ANDERSON RICHARD ROX , VOSBURGH KIRBY , PARRISH JOHN A
发明人： ANDERSON RICHARD ROX , VOSBURGH KIRBY , PARRISH JOHN A
IPC分类号： A61B8/00 , A61H1/00
CPC分类号： A61N7/00 , A61B8/06 , A61B8/13 , A61B8/14 , A61B2090/378 , A61N7/02
摘要： Various methods and devices for minimally invasive treatment and prevention of conditions of the fascia are provided. In one aspect, a method includes providing an acoustic wave source effective to deliver a focused acoustic wave to a target site within a patient's body, and focusing an acoustic wave through a patient's skin such that at least one location in the patient's fascia is fenestrated in a desired pattern.
摘要翻译：提供了用于微创治疗和预防筋膜状况的各种方法和装置。在一个方面，一种方法包括提供有效地将聚焦声波传递到患者体内的目标部位并且将声波聚焦通过患者皮肤的声波源，使得患者的筋膜中的至少一个位置在所需的图案。

9. 发明申请

WO2005096766A3 METHODS AND APPARATUS FOR TREATMENT OF OCULAR MELANOSIS 审中-公开
标题翻译：用于治疗眼球炎的方法和装置
公开(公告)号：WO2005096766A3
公开(公告)日：2005-12-22
申请号：PCT/US2005011438
申请日：2005-04-04
申请人： GEN HOSPITAL CORP , ANDERSON RICHARD ROX , AKITA HIROTAKA
发明人： ANDERSON RICHARD ROX , AKITA HIROTAKA
IPC分类号： A61B18/20 , A61F9/009 , A61N5/067
CPC分类号： A61F9/009 , A61B18/203 , A61B2018/00452 , A61F9/008 , A61F2009/00865
摘要： The invention entails a novel system and method for modifying scleral pigmentation. More particularly, the invention entails a novel system and method for treating Ocular Melanosis (OM). The invention contemplates a system and method for treating OM that uses lasers with modified pulse widths and low power to whiten the sclera without causing damage to the retina. Ultimately, a system has been developed that uses of low laser pulse fluences considerably less than those used for treating nevus of Ota on the skin. The system limits the risk of retinal injury by use of (a) a small exposure spot size and (b) a high numerical aperture (NA) optical beam with fluences of between about 0.5 J/cm and 5.0 J/Am , significantly lower than many currently available laser treatments. In a preferred embodiment, the system of the invention uses a laser with a wavelength in the visible and near-infrared spectrum and a pulse width from about 1 ns - 100 microseconds.
摘要翻译：本发明涉及一种用于改善巩膜色素沉着的新型系统和方法。更具体地说，本发明需要一种治疗眼部黑色素瘤（OM）的新型系统和方法。本发明考虑了一种用于治疗OM的系统和方法，其使用具有修改的脉冲宽度和低功率的激光来增加巩膜而不会对视网膜造成损害。最终，已经开发了一种使用低激光脉冲通量的系统，其显着小于用于治疗皮肤上的Ota痣的那些。该系统通过使用（a）小的曝光光斑尺寸和（b）具有约0.5J / cm 2和5.0J / Am 2之间的通量的高数值孔径（NA）光束来限制视网膜损伤的风险， 2>，显着低于许多目前可用的激光治疗。在优选实施例中，本发明的系统使用具有可见光和近红外光谱波长的激光，脉冲宽度约为1ns-100微秒。

10. 发明申请

WO2010120769A2 METHOD AND APPARATUS FOR MULTIMODAL IMAGING OF BIOLOGICAL TISSUE 审中-公开
标题翻译：用于生物组织多成像成像的方法和装置
公开(公告)号：WO2010120769A2
公开(公告)日：2010-10-21
申请号：PCT/US2010030880
申请日：2010-04-13
申请人： GEN HOSPITAL CORP , YAROSLAVSKY ANNA N , SALOMATINA ELENA , ANDERSON RICHARD ROX
发明人： YAROSLAVSKY ANNA N , SALOMATINA ELENA , ANDERSON RICHARD ROX
IPC分类号： G01N21/25 , G01N21/64 , G01N33/483
CPC分类号： G01N21/6456 , G01N21/6445
摘要： The present invention is directed to a novel multi- wavelength imaging method and apparatus that enables rapid imaging of tissue regions with accurate identification of tissue types within the region. Optical properties, such as co- polarized or cross-polarized fluorescence or reflectance intensity, optical density and/or reflectance, can be determined at a plurality of locations within the tissue region for each wavelength. Said properties at the two wavelengths, including calculated derivatives of the optical property with respect to wavelength, can be analyzed to image tissue structures and identify tissue types within the tissue region more accurately than can be achieved based on properties measured at a single wavelength.
摘要翻译：本发明涉及一种新颖的多波长成像方法和装置，其能够通过准确识别该区域内的组织类型来快速成像组织区域。可以在针对每个波长的组织区域内的多个位置处确定光学性质，例如共极化或交叉极化荧光或反射强度，光密度和/或反射率。可以分析在两个波长处的所述性质，包括相对于波长的光学性质的计算导数，以便比基于在单个波长测量的性质可以更精确地识别组织结构并识别组织区域内的组织类型。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式