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1. 发明申请

WO2013056379A1 SYSTEM FOR NONINVASIVE OPTICAL MEASUREMENTS OF PHYSIOLOGICAL PROPERTIES IN TISSUE 审中-公开
标题翻译：非组织光学测量系统在组织中的生理特性
公开(公告)号：WO2013056379A1
公开(公告)日：2013-04-25
申请号：PCT/CH2011/000247
申请日：2011-10-19
申请人： BIOVOTION AG , ZAKHAROV, Pavel , TALARY, Mark , CADUFF, Andreas
发明人： ZAKHAROV, Pavel , TALARY, Mark , CADUFF, Andreas
IPC分类号： A61B5/1455
CPC分类号： A61B5/0295 , A61B5/02416 , A61B5/1107 , A61B5/14551 , A61B5/721 , G06F19/00
摘要： Embodiments of the present invention comprise systems and methods for noninvasive measurements of physiological properties of tissue. The system comprises a light emitter, an optical detector, a mechanical sensor and a processor. The light emitter is capable of emitting light of at least two different wavelengths and comprises at least one light source. The processor is capable of evaluating physiological properties of the tissues from measurements of the optical and the mechanical sensor. More precisely, the processor is capable of evaluating physiological properties of venous blood by using data measured by the mechanical sensor and the optical detector. For example, the oxygenation of venous blood can be measured. Furthermore, the systems can optionally comprise a light emitter which emits three wavelengths and/or the light emitter and the optical detector are arranged in reflection geometry and are located at a distance of at most 10 mm from each other.
摘要翻译：本发明的实施例包括用于非侵入性测量组织生理特性的系统和方法。该系统包括光发射器，光学检测器，机械传感器和处理器。光发射器能够发射至少两个不同波长的光，并且包括至少一个光源。处理器能够通过光学和机械传感器的测量来评估组织的生理特性。更准确地说，处理器能够通过使用由机械传感器和光学检测器测量的数据来评估静脉血的生理特性。例如，可以测量静脉血的氧合。此外，系统可以可选地包括发射三个波长的光发射器和/或光发射器，并且光学检测器以反射几何形状布置并且位于彼此至多10mm的距离处。

2. 发明申请

WO2009152625A1 METHOD AND DEVICE FOR CHARACTERIZING THE EFFECT OF A SKIN TREATMENT AGENT ON SKIN 审中-公开
标题翻译：用于表征皮肤治疗剂对皮肤的影响的方法和装置
公开(公告)号：WO2009152625A1
公开(公告)日：2009-12-23
申请号：PCT/CH2008/000276
申请日：2008-06-18
申请人： SOLIANIS HOLDING AG , MEGEJ, Alexander , CADUFF, Andreas , TALARY, Mark
发明人： MEGEJ, Alexander , CADUFF, Andreas , TALARY, Mark
IPC分类号： G01B7/26 , A61B5/103 , G01N27/00 , H01P3/00 , A61B18/18 , G01R27/26 , A61B5/00 , A61B5/053 , A61K49/00
CPC分类号： H01P11/003 , A61B5/0507 , A61B5/0531 , A61B5/442 , G01B7/26
摘要： In a method for characterizing skin treatment agent, a device having several sets (5) of electrodes is applied to the skin. The electrode sets have differing electrode distances (W), such that fields having different reach can be generated. Inverse profiling is used to calculate the dielectric permittivities of individual skin layers, which in turn allows to observe the water transport mechanism in the skin. These transport mechanisms can be used to assess the effect of the agent on the skin. An advantageous device for implementing this method comprises coplanar waveguides for generating the fields.
摘要翻译：在用于表征皮肤处理剂的方法中，将具有几组（5）电极的装置施加到皮肤上。电极组具有不同的电极距离（W），使得可以产生具有不同范围的场。反向轮廓用于计算各皮肤层的介电常数，从而可以观察皮肤中的水分输送机制。这些运输机制可用于评估药剂对皮肤的影响。用于实现该方法的有利装置包括用于产生场的共面波导。

3. 发明申请

WO2009152624A1 DEVICE AND METHOD FOR DETERMINING AT LEAST ONE CHARACTERIZING PARAMETER OF MULTILAYER BODY TISSUE 审中-公开
标题翻译：用于确定多层体表组织的一个特征参数的装置和方法
公开(公告)号：WO2009152624A1
公开(公告)日：2009-12-23
申请号：PCT/CH2008/000275
申请日：2008-06-18
申请人： SOLIANIS HOLDING AG , MEGEJ, Alexander , CADUFF, Andreas , TALARY, Mark
发明人： MEGEJ, Alexander , CADUFF, Andreas , TALARY, Mark
IPC分类号： A61B5/00
CPC分类号： A61B5/1495 , A61B5/0507 , A61B5/0537 , A61B5/14532 , A61B5/4869
摘要： A device for the non-invasive measurement of a glucose level, body hydration or another characterizing parameter of body tissue comprises at least two coplanar waveguides (5) arranged on a common support (3). An AC signal is applied to the first ends of the coplanar waveguides (5), and the signal arriving at the second end is measured. The coplanar waveguides (5) have differing gap widths (W), such that their electric fields have different reach into the body tissue. This allows obtain depth resolved information about the permittivities of individual tissue layers and to obtain more accurate results.
摘要翻译：用于非侵入性测量葡萄糖水平，身体水合或身体组织的另一特征参数的装置包括布置在公共支撑件（3）上的至少两个共面波导（5）。将AC信号施加到共面波导（5）的第一端，并且测量到达第二端的信号。共面波导（5）具有不同的间隙宽度（W），使得它们的电场具有与身体组织不同的距离。这可以获得关于单个组织层的介电常数的深度解析信息并获得更准确的结果。

4. 发明公开

EP2768391A1 SYSTEM FOR NONINVASIVE OPTICAL MEASUREMENTS OF PHYSIOLOGICAL PROPERTIES IN TISSUE 有权转让
标题翻译： SYSTEM FOR组织的非侵入光学测量生理学特性
公开(公告)号：EP2768391A1
公开(公告)日：2014-08-27
申请号：EP11773662.9
申请日：2011-10-19
申请人： Biovotion AG
发明人： ZAKHAROV, Pavel , TALARY, Mark , CADUFF, Andreas
IPC分类号： A61B5/1455
CPC分类号： A61B5/0295 , A61B5/02416 , A61B5/1107 , A61B5/14551 , A61B5/721 , G06F19/00
摘要： Embodiments of the present invention comprise systems and methods for noninvasion measurements of physiological properties of tissues. The system comprises a light emitter, an optical detector, a mechanical sensor and a processor. The light emitter is capable of emitting light of at least two different wavelengths and comprises at least one light source. The processor is capable of evaluating physiological properties of the tissues from measurements of the optical and the mechanical sensor. More precisely, the processor is capable of evaluating physiological properties of venous blood by using data measured by the mechanical sensor and the optical detector. For example, the oxygenation of venous blood can be measured. Furthermore, the systems can optionally comprise a light emitter which emits three wavelengths and/or the light emitter and the optical detector are arranged in reflection geometry and are located at a distance of at most 10 mm from each other.

5. 发明授权

EP2321613B1 METHOD FOR CHARACTERIZING THE EFFECT OF A SKIN TREATMENT AGENT ON SKIN 有权转让
公开(公告)号：EP2321613B1
公开(公告)日：2019-09-04
申请号：EP08757269.9
申请日：2008-06-18
申请人： Biovotion AG
发明人： MEGEJ, Alexander , CADUFF, Andreas , TALARY, Mark
IPC分类号： G01B7/26 , A61B5/103 , G01N27/00 , H01P3/00 , A61B18/18 , G01R27/26 , A61B5/00 , A61B5/053 , A61K49/00

6. 发明授权

EP2768391B1 METHOD FOR NONINVASIVE OPTICAL MEASUREMENTS OF PHYSIOLOGICAL PROPERTIES IN TISSUE 有权转让
公开(公告)号：EP2768391B1
公开(公告)日：2019-05-01
申请号：EP11773662.9
申请日：2011-10-19
申请人： Biovotion AG
发明人： ZAKHAROV, Pavel , TALARY, Mark , CADUFF, Andreas
IPC分类号： A61B5/1455

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