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1. 发明申请

WO0021558A9 REVERSAL OF VIRAL-INDUCED SYSTEMIC SHOCK AND RESPIRATORY DISTRESS BY BLOCKADE OF THE LYMPHOTOXIN BETA PATHWAY 审中-公开
标题翻译：病毒诱发的系统性震颤和呼吸道感染的反应
公开(公告)号：WO0021558A9
公开(公告)日：2001-05-25
申请号：PCT/US9923477
申请日：1999-10-08
申请人： BIOGEN INC , UNIV EMORY , BROWNING JEFF , PUGLIELLI MARYANN , AHMED RAFI
发明人： BROWNING JEFF , PUGLIELLI MARYANN , AHMED RAFI
IPC分类号： A61K45/00 , A61K38/00 , A61K38/17 , A61K38/19 , A61K38/22 , A61K39/395 , A61P31/12 , C07K16/24 , C07K16/28
CPC分类号： C07K16/241 , A61K38/1793 , A61K38/191 , A61K2039/505 , C07K16/242 , C07K16/2866 , C07K2319/30
摘要： This invention provides methods of inducing an antiviral response in an individual comprising administering to the individual an effective amount of a LT-B blocking agent and a pharmaceutically acceptable carrier. In particular this invention provides methods for treating viral-induced systemic shock and respiratory distress.
摘要翻译：本发明提供在个体中诱导抗病毒应答的方法，包括向个体施用有效量的LT-B封闭剂和药学上可接受的载体。特别地，本发明提供了治疗病毒诱导的全身性休克和呼吸窘迫的方法。

2. 发明申请

WO0142291A3 POLYNUCLEOTIDES AND POLYPEPTIDES ENCODED THEREBY 审中-公开
标题翻译：多核苷酸和编码的多核苷酸
公开(公告)号：WO0142291A3
公开(公告)日：2002-06-13
申请号：PCT/US0033538
申请日：2000-12-11
申请人： CURAGEN CORP , BIOGEN INC , PEYMAN JOHN A , CARULLI JOHN , BROWNING JEFF , HESSION CATHERINE
发明人： PEYMAN JOHN A , CARULLI JOHN , BROWNING JEFF , HESSION CATHERINE
IPC分类号： A61K38/00 , C07K14/705 , C07K14/47 , A61K38/16 , A61K39/395 , A61K48/00 , C07K16/18 , C12N5/10 , C12N15/12 , C12Q1/68 , G01N33/53
CPC分类号： C07K14/705 , A61K38/00
摘要： The invention provides polypeptides, designated herein as TLMP polypeptides, as well as polynucleotides encoding TLMP polypeptides, and antibodies that immunospecifically-bind to TLMP polypeptide or polynucleotide, or derivatives, variants, mutants or fragments thereof. The invention additionally provides methods in which the TLMP polypeptide, polynucleotide, and antibody are used in the detection, prevention, and treatment of a broad range of pathological states.
摘要翻译：本发明提供了本文称为TLMP多肽的多肽，以及编码TLMP多肽的多核苷酸，以及免疫特异性结合TLMP多肽或多核苷酸或其衍生物，变体，突变体或其片段的抗体。本发明另外提供了用于检测，预防和治疗广泛病理状态的TLMP多肽，多核苷酸和抗体的方法。

3. 发明专利

CA2344049A1 REVERSAL OF VIRAL-INDUCED SYSTEMIC SHOCK AND RESPIRATORY DISTRESS BY BLOCKADE OF THE LYMPHOTOXIN BETA PATHWAY 未知
公开(公告)号：CA2344049A1
公开(公告)日：2000-04-20
申请号：CA2344049
申请日：1999-10-08
申请人： BIOGEN INC , UNIV EMORY
发明人： AHMED RAFI , PUGLIELLI MARYANN , BROWNING JEFF
IPC分类号： A61K45/00 , A61K38/00 , A61K38/17 , A61K38/19 , A61K38/22 , A61K39/395 , A61P31/12 , C07K16/24 , C07K16/28 , C07K14/715
摘要： This invention provides methods of inducing an antiviral response in an individual comprising administering to the individual an effective amount of a LT-B blocking agent and a pharmaceutically acceptable carrier. In particular this invention provides methods for treating viral-induced systemic shock an d respiratory distress.

4. 发明专利

CA2344049C REVERSAL OF VIRAL-INDUCED SYSTEMIC SHOCK AND RESPIRATORY DISTRESS BY BLOCKADE OF THE LYMPHOTOXIN BETA PATHWAY 未知
公开(公告)号：CA2344049C
公开(公告)日：2009-12-15
申请号：CA2344049
申请日：1999-10-08
申请人： BIOGEN INC , UNIV EMORY
发明人： BROWNING JEFF , AHMED RAFI , PUGLIELLI MARYANN
IPC分类号： A61K39/395 , A61K45/00 , A61K38/00 , A61K38/17 , A61K38/19 , A61K38/22 , A61P31/12 , C07K14/715 , C07K16/24 , C07K16/28
摘要： This invention provides methods of inducing an antiviral response in an individual comprising administering to the individual an effective amount of a LT-B blocking agent and a pharmaceutically acceptable carrier. In particular this invention provides methods for treating viral-induced systemic shock and respiratory distress.

5. 发明专利

AU777492B2 Reversal of viral-induced systemic shock and respiratory distress by blockade of the lymphotoxin beta pathway 未知
公开(公告)号：AU777492B2
公开(公告)日：2004-10-21
申请号：AU6296499
申请日：1999-10-08
申请人： BIOGEN INC , UNIV EMORY
发明人： BROWNING JEFF , PUGLIELLI MARYANN , AHMED RAFI
IPC分类号： A61K45/00 , A61K38/00 , A61K38/17 , A61K38/19 , A61K38/22 , A61K39/395 , A61P31/12 , C07K16/24 , C07K16/28 , C07K14/715
摘要： This invention provides methods of inducing an antiviral response in an individual comprising administering to the individual an effective amount of a LT-B blocking agent and a pharmaceutically acceptable carrier. In particular this invention provides methods for treating viral-induced systemic shock and respiratory distress.

6. 发明专利

SK4662001A3 REVERSAL OF VIRAL-INDUCED SYSTEMIC SHOCK AND RESPIRATORY DISTRESS BY BLOCKADE OF THE LYMPHOTOXIN BETA PATHWAY 未知
公开(公告)号：SK4662001A3
公开(公告)日：2001-11-06
申请号：SK4662001
申请日：1999-10-08
申请人： BIOGEN INC , UNIV EMORY
发明人： BROWNING JEFF , PUGLIELLI MARYANN , AHMED RAFI
IPC分类号： A61K45/00 , A61K38/00 , A61K38/17 , A61K38/19 , A61K38/22 , A61K39/395 , A61P31/12 , C07K16/24 , C07K16/28
摘要： This invention provides methods of inducing an antiviral response in an individual comprising administering to the individual an effective amount of a LT-B blocking agent and a pharmaceutically acceptable carrier. In particular this invention provides methods for treating viral-induced systemic shock and respiratory distress.

7. 发明专利

PL347177A1 REVERSAL OF VIRAL-INDUCED SYSTEMIC SHOCK AND RESPIRATORY DISTRESS BY BLOCKADE OF THE LYMPHOTOXIN BETA PATHWAY 未知
公开(公告)号：PL347177A1
公开(公告)日：2002-03-25
申请号：PL34717799
申请日：1999-10-08
申请人： BIOGEN INC , UNIV EMORY
发明人： BROWNING JEFF , PUGLIELLI MARYANN , AHMED RAFI
IPC分类号： A61K45/00 , A61K38/00 , A61K38/17 , A61K38/19 , A61K38/22 , A61K39/395 , A61P31/12 , C07K16/24 , C07K16/28 , A61P11/16
摘要： This invention provides methods of inducing an antiviral response in an individual comprising administering to the individual an effective amount of a LT-B blocking agent and a pharmaceutically acceptable carrier. In particular this invention provides methods for treating viral-induced systemic shock and respiratory distress.

8. 发明专利

BR9915025A 未知
公开(公告)号：BR9915025A
公开(公告)日：2001-08-14
申请号：BR9915025
申请日：1999-10-08
申请人： BIOGEN INC , UNIV EMORY
发明人： BROWNING JEFF , PUGLIELLI MARYANN , AHMED RAFI
IPC分类号： A61K45/00 , A61K38/00 , A61K38/17 , A61K38/19 , A61K38/22 , A61K39/395 , A61P31/12 , C07K16/24 , C07K16/28
摘要： This invention provides methods of inducing an antiviral response in an individual comprising administering to the individual an effective amount of a LT-B blocking agent and a pharmaceutically acceptable carrier. In particular this invention provides methods for treating viral-induced systemic shock and respiratory distress.

9. 发明专利

TR200100974T2 未知
公开(公告)号：TR200100974T2
公开(公告)日：2001-11-21
申请号：TR200100974
申请日：1999-10-08
申请人： BIOGEN INC , UNIV EMORY
发明人： BROWNING JEFF , PUGIELLI MARYANN , AHMED RAFI
IPC分类号： A61K45/00 , A61K38/00 , A61K38/17 , A61K38/19 , A61K38/22 , A61K39/395 , A61P31/12 , C07K16/24 , C07K16/28 , C07K16/02 , C07K14/715
摘要： This invention provides methods of inducing an antiviral response in an individual comprising administering to the individual an effective amount of a LT-B blocking agent and a pharmaceutically acceptable carrier. In particular this invention provides methods for treating viral-induced systemic shock and respiratory distress.

10. 发明申请

WO02059933A3 VERTICALLY TRANSLATABLE CHUCK ASSEMBLY AND METHOD FOR A PLASMA REACTOR SYSTEM 审中-公开
标题翻译：用于等离子体反应器系统的垂直可翻转组件和方法
公开(公告)号：WO02059933A3
公开(公告)日：2002-10-10
申请号：PCT/US0148851
申请日：2001-12-20
申请人： TOKYO ELECTRON LTD , JOHNSON WAYNE L , FINK STEVEN T , BROWNING JEFF , JEVTIC JOVAN
发明人： JOHNSON WAYNE L , FINK STEVEN T , BROWNING JEFF , JEVTIC JOVAN
IPC分类号： H01J37/32 , H01L21/00
CPC分类号： H01L21/67069 , H01J37/32082 , H01J37/32174
摘要： A chuck assembly (110) for supporting a workpiece (116) within a plasma reactor chamber (60) having sidewalls (64) surrounding an interior region (65) capable of supporting a plasma. The assembly includes a chuck base (130) and a plurality of support arms (150A-150C) extending outwardly from the chuck base perimeter to the chamber sidewalls. The support arms are adapted to support the chuck base within the interior region, while also being adapted to provide a path for mechanically, electrically, pneumatically and/or fluidly communicating with the chuck assembly from outside the chamber. The chuck assembly includes a workpiece support member (160) arranged above the chuck base, capable of supporting the workpiece and serving as a chuck electrode. The workpiece support member is supported by one or more vertical translation member (168) arranged between and operatively connected to the chuck base and the workpiece support member. The chuck assembly includes a match network (180MN), wherein at least a portion of the match network is mounted directly to the workpiece support member. The use of the support arms allows for the positioning of a vacuum pump system (250) directly beneath the chuck assembly.
摘要翻译：一种用于在具有围绕能够支撑等离子体的内部区域（65）的侧壁（64）的等离子体反应器室（60）内支撑工件（116）的卡盘组件（110）。组件包括卡盘基座（130）和从卡盘基部周边向外延伸到腔室侧壁的多个支撑臂（150A-150C）。所述支撑臂适于在所述内部区域内支撑所述卡盘基座，同时还适于提供用于从所述腔室外部与所述卡盘组件机械，电气，气动和/或流体连通的路径。卡盘组件包括布置在卡盘基座上方的能够支撑工件并用作卡盘电极的工件支撑构件（160）。工件支撑构件由一个或多个垂直平移构件（168）支撑，该垂直平移构件布置在卡盘基座和工件支撑构件之间并且可操作地连接到卡盘基座和工件支撑构件上。卡盘组件包括匹配网络（180MN），其中匹配网络的至少一部分直接安装到工件支撑构件。支撑臂的使用允许将真空泵系统（250）直接定位在卡盘组件的正下方。

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