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1. 发明申请

WO2012125132A1 MEDICAL INJECTOR WITH ROTATABLE RATCHETING PLUNGER 审中-公开
标题翻译：医用注射器与可旋转的冲击钻
公开(公告)号：WO2012125132A1
公开(公告)日：2012-09-20
申请号：PCT/US2011/000492
申请日：2011-03-17
申请人： BECTON, DICKINSON AND COMPANY , CRONENBERG, Richard , WU, Haiming
发明人： CRONENBERG, Richard , WU, Haiming
IPC分类号： A61M5/315
CPC分类号： A61M5/3158 , A61M5/1782 , A61M5/24 , A61M5/31553 , A61M5/31555 , A61M5/31581
摘要： A medical injector has a body with a displaceable plunger, which has a plurality of ratchet teeth along its length. An indexer is provided to engage the plunger, wherein the indexer is configured to allow the plunger to displace distally. The medical injector also includes an actuator having an engagement portion formed to engage the ratchet teeth. The.actuator is displaceable to a ready state, the engagement portion being displaced proximally relative to the plunger with the actuator being displaced to the ready state. The indexer prevents proximal movement of the plunger, thereby allowing the engagement portion to bypass one or more of the ratchet teeth with the actuator being displaced to the ready state. The plunger is slidably displaceable relative to the body, and rotatable relative to the body to selectively engage and disengage ratchet teeth engaged with the indexer and the actuator.
摘要翻译：医用注射器具有带有位移柱塞的主体，该主体沿其长度具有多个棘轮齿。提供分度器以接合柱塞，其中分度器构造成允许柱塞向远侧位移。医疗注射器还包括具有形成为接合棘轮齿的接合部的致动器。致动器可移动到就绪状态，接合部分相对于柱塞向近侧位移，致动器被移动到就绪状态。分度器防止柱塞的近端运动，从而允许接合部分绕过一个或多个棘轮齿，致动器被移动到就绪状态。柱塞相对于主体可滑动地移动，并且相对于主体可旋转，以选择性地接合和脱离与分度器和致动器啮合的棘齿。

2. 发明申请

WO2011068531A1 INJECTION PEN WITH DIAL BACK AND LAST DOSE CONTROL 审中-公开
标题翻译：注射笔与背部和最后的剂量控制
公开(公告)号：WO2011068531A1
公开(公告)日：2011-06-09
申请号：PCT/US2010/003059
申请日：2010-11-30
申请人： BECTON, DICKINSON AND COMPANY , CRONENBERG, Richard , QUINN, Michael , WU, Haiming
发明人： CRONENBERG, Richard , QUINN, Michael , WU, Haiming
IPC分类号： A61M5/00
CPC分类号： A61M5/31548 , A61M5/24 , A61M5/2466 , A61M5/31535 , A61M5/31541 , A61M5/31543 , A61M5/31551 , A61M5/3156 , A61M5/31563 , A61M5/3157 , A61M5/31573 , A61M5/31575 , A61M5/31585 , A61M5/31595 , A61M5/3202 , A61M5/347 , A61M2005/2407 , A61M2005/2488 , A61M2005/2492 , A61M2205/581
摘要： A medication injection pen is provided comprising a housing (218), for housing a dose set knob (220), a leadscrew (226), a driver (224), a setback member (222), and a dose stop member (228). The dose set knob (220) is rotatable with respect to said housing (218) to set a desired injection dose, and comprises at least one internal thread (291). The leadscrew (226) includes a thread element by which it is advanceable in a first direction via a corresponding thread engagement, said first direction being that which expels medication from a cartridge (36). The driver (224) is rotationally fixed to said leadscrew (226) for preventing relative rotation therebetween, said driver (224) being rotatable in a first direction to rotate and advance said leadscrew (226) in said first direction. The setback member (222) is rotationally fixed to said driver (224) for preventing relative rotation therebetween.
摘要翻译：提供了一种药物注射笔，其包括用于容纳剂量设定旋钮（220），丝杠（226），驱动器（224），挫折部件（222）和剂量停止部件（228）的壳体（218）。剂量设定旋钮220相对于所述壳体218可旋转以设定所需的注射剂量，并且包括至少一个内螺纹291。丝杠（226）包括螺纹元件，通过该螺纹元件可以通过相应的螺纹接合在第一方向上前进，所述第一方向是从药筒（36）排出药物的方向。驱动器（224）旋转地固定到所述丝杠（226）上以防止它们之间的相对旋转，所述驱动器（224）可沿第一方向旋转，并沿着所述第一方向推进所述丝杠（226）。遏制构件（222）旋转地固定到所述驱动器（224），以防止它们之间的相对旋转。

3. 发明申请

WO2013134614A2 DRUG RECONSTITUTION SYSTEM 审中-公开
标题翻译：药物重组系统
公开(公告)号：WO2013134614A2
公开(公告)日：2013-09-12
申请号：PCT/US2013/029807
申请日：2013-03-08
申请人： BECTON, DICKINSON AND COMPANY
发明人： CRONENBERG, Richard , WU, Haiming
IPC分类号： A61M5/19
CPC分类号： A61M5/31505 , A61J1/2048 , A61M5/19 , A61M5/24 , A61M5/2448 , A61M5/31596 , A61M2005/31508 , A61M2202/064
摘要： A system including an adapter for sequential engagement with a cartridge containing a first substance and a vial containing a second substance is disclosed. The adapter is configured to first engage with the vial and subsequently engage with the cartridge such that the cartridge is in fluid communication with the vial via the adapter. The system includes a latch member engageable with a portion of the cartridge. A plunger rod includes a protrusion and is adapted to communicate with the latch member, the plunger rod being transitionable from a disengaged position, in which the protrusion of the plunger rod is disengaged from the latch member and the latch member is locked to the cartridge, to an engaged position, in which the protrusion is engaged with the latch member and the latch member is unlocked from the cartridge and locked to the plunger rod.
摘要翻译：公开了包括用于与包含第一物质的药筒顺序接合的适配器和包含第二物质的小瓶的系统。适配器被配置为首先与小瓶接合并随后与盒接合，使得盒经由适配器与小瓶流体连通。该系统包括可与盒的一部分接合的闩锁构件。柱塞杆包括突起并且适于与闩锁构件连通，柱塞杆可从分离位置转换，其中柱塞杆的突起与闩锁构件脱离，并且闩锁构件锁定到盒，到接合位置，其中突起与闩锁构件接合，并且闩锁构件从盒中解锁并锁定到柱塞杆。

4. 发明申请

WO2014179776A1 FLOW PATHWAY SUBASSEMBLY 审中-公开
标题翻译：流动通道分组
公开(公告)号：WO2014179776A1
公开(公告)日：2014-11-06
申请号：PCT/US2014/036703
申请日：2014-05-02
申请人： BECTON, DICKINSON AND COMPANY
发明人： WU, Haiming , FERREIRA, Danial P.
IPC分类号： A61M5/20
CPC分类号： A61M5/1413 , A61M5/14248 , A61M5/145 , A61M5/1454 , A61M5/162 , A61M5/1626 , A61M5/16813 , A61M5/3134 , A61M39/20 , A61M39/22 , A61M2005/14252 , A61M2005/14256 , A61M2005/2073 , A61M2005/2474 , A61M2205/195 , A61M2205/70 , A61M2207/00 , B65B55/04
摘要： A flow pathway subassembly (264, 278) including medicament flow pathway components of a medical device, and a holder (270, 280) configured for holding the components so that a center of gravity of the subassembly is disposed substantially on a central longitudinal axis of the subassembly.
摘要翻译：包括医疗装置的药物流动路径部件的流动路径子组件（264,278）以及保持器（270,280），所述保持器（270,280）被配置为保持所述部件，使得所述子组件的重心是基本上设置在子组件的中心纵轴上。

5. 发明申请

WO2014179774A1 DRUG DELIVERY DEVICE 审中-公开
标题翻译：药物递送装置
公开(公告)号：WO2014179774A1
公开(公告)日：2014-11-06
申请号：PCT/US2014/036701
申请日：2014-05-02
申请人： BECTON, DICKINSON AND COMPANY
发明人： WU, Haiming , FERREIRA, Danial P.
IPC分类号： A61M5/32
CPC分类号： A61M5/1413 , A61M5/14248 , A61M5/145 , A61M5/1454 , A61M5/162 , A61M5/1626 , A61M5/16813 , A61M5/3134 , A61M39/20 , A61M39/22 , A61M2005/14252 , A61M2005/14256 , A61M2005/2073 , A61M2005/2474 , A61M2205/195 , A61M2205/70 , A61M2207/00 , B65B55/04
摘要： A drug delivery device for injecting medicament, the device including a main body having a surface for contacting a patient, an actuation button (110, 420, 436) movably disposed relative to the main body, and a reservoir disposed within the main body for containing a medicament. The device also includes a needle having a distal end for insertion into a patient, and a lumen extending proximally from the distal end, wherein said lumen is fluidly connectable with the reservoir. The device further includes a removable needle cover (114, 400) for selectively covering the distal end of the needle and selectively preventing movement of the actuation button relative to the main body that initiates activation of the device.
摘要翻译：一种用于注射药物的药物输送装置，所述装置包括具有用于接触患者的表面的主体，可移动地相对于主体布置的致动按钮（110,420,436），以及布置在主体内用于容纳药物的贮存器。该装置还包括具有用于插入患者体内的远端的针以及从远端向近端延伸的内腔，其中所述内腔可与储存器流体连接。该装置还包括用于选择性地覆盖针的远端的可移除针头盖（114,400），并且选择性地防止致动按钮相对于主体的移动，从而启动装置的激活。

6. 发明申请

WO2013134246A1 TRANSFER SET WITH FLOATING NEEDLE FOR DRUG RECONSTITUTION 审中-公开
标题翻译：带有用于药物重新配置的浮动针的转移装置
公开(公告)号：WO2013134246A1
公开(公告)日：2013-09-12
申请号：PCT/US2013/029088
申请日：2013-03-05
申请人： BECTON, DICKINSON AND COMPANY
发明人： WU, Haiming , CRONENBERG, Richard
IPC分类号： A61J1/20 , A61J1/06 , A61J1/14
CPC分类号： A61J1/2089 , A61J1/062 , A61J1/1406 , A61J1/1481 , A61J1/201 , A61J1/2013 , B65B3/003
摘要： An adapter assembly for establishing bidirectional fluid connection between a cartridge and a vial includes a housing having an open first end adapted to engage the cartridge and a second open end adapted to engage the vial. The adapter includes a needle assembly having a first tip and a second tip, with the needle assembly disposed within the housing and at least partially supported by a needle holder. The needle assembly is movable relative to the housing from an initial position in which the first and second tip are isolated from the cartridge and vial, to an end of use position, in which first tip is engaged with the vial and the second tip is engaged with the cartridge, establishing fluid communication therebetween. The needle assembly is maintained in the initial position by a locking structure which is released by rotationally advancing the needle holder relative to the housing.
摘要翻译：用于在盒和小瓶之间建立双向流体连接的适配器组件包括壳体，该壳体具有适于接合盒的敞开的第一端和适于接合小瓶的第二开口端。适配器包括具有第一尖端和第二末端的针组件，其中针组件设置在壳体内并且至少部分地由针保持器支撑。针组件可以从第一和第二尖端与药筒和小瓶隔离的初始位置相对于壳体移动到使用位置的终点，其中第一尖端与小瓶接合，并且第二末端接合与墨盒之间建立流体连通。针组件通过锁定结构保持在初始位置，锁定结构通过使针保持器相对于壳体旋转地前进而释放。

7. 发明授权

EP2991707B1 FLOW PATHWAY SUBASSEMBLY 有权转让
公开(公告)号：EP2991707B1
公开(公告)日：2020-12-02
申请号：EP14791686.0
申请日：2014-05-02
申请人： Becton, Dickinson and Company
发明人： WU, Haiming , FERREIRA, Danial P.
IPC分类号： A61M5/20 , A61M5/31 , A61M5/14 , A61M5/142 , A61M5/145 , A61M5/162 , A61M5/24 , A61M39/20 , A61M39/22 , A61M5/168

8. 发明授权

EP2686046B1 MEDICAL INJECTOR WITH ROTATABLE RATCHETING PLUNGER 有权转让
公开(公告)号：EP2686046B1
公开(公告)日：2019-05-01
申请号：EP11861021.1
申请日：2011-03-17
申请人： Becton, Dickinson and Company
发明人： CRONENBERG, Richard , WU, Haiming
IPC分类号： A61M5/315

9. 发明公开

EP2991707A1 FLOW PATHWAY SUBASSEMBLY 有权转让
标题翻译： FLUSSWEGBAUGRUPPE
公开(公告)号：EP2991707A1
公开(公告)日：2016-03-09
申请号：EP14791686.0
申请日：2014-05-02
申请人： Becton, Dickinson and Company
发明人： WU, Haiming , FERREIRA, Danial P.
IPC分类号： A61M5/20
CPC分类号： A61M5/1413 , A61M5/14248 , A61M5/145 , A61M5/1454 , A61M5/162 , A61M5/1626 , A61M5/16813 , A61M5/3134 , A61M39/20 , A61M39/22 , A61M2005/14252 , A61M2005/14256 , A61M2005/2073 , A61M2005/2474 , A61M2205/195 , A61M2205/70 , A61M2207/00 , B65B55/04
摘要： A flow pathway subassembly (264, 278) including medicament flow pathway components of a medical device, and a holder (270, 280) configured for holding the components so that a center of gravity of the subassembly is disposed substantially on a central longitudinal axis of the subassembly.
摘要翻译：一种用于注射药物的药物递送装置，该装置包括具有用于接触患者的表面的主体，相对于主体可移动地设置的致动按钮（110,420,436）和设置在主体内的容纳物药物。该装置还包括具有用于插入病人的远端的针和从远端向近端延伸的内腔，其中所述内腔可与储液器流体连接。该装置还包括用于选择性地覆盖针的远端的可移除的针盖（114,400），并且选择性地防止致动按钮相对于主体的移动，从而启动装置的启动。

10. 发明公开

EP4134116A1 DRUG DELIVERY DEVICE 有权
公开(公告)号：EP4134116A1
公开(公告)日：2023-02-15
申请号：EP22197787.9
申请日：2014-05-02
申请人： Becton, Dickinson and Company
发明人： WU, Haiming , FERREIRA, Danial P.
IPC分类号： A61M5/32 , A61M5/145 , A61M5/14 , A61M5/162 , A61M5/31 , A61M5/142 , A61M5/168 , A61M5/20 , A61M5/24 , A61M39/20 , A61M5/315 , A61M39/22
摘要： A drug delivery device for injecting medicament, the device including a main body having a surface for contacting a patient, an actuation button (110, 420, 436) movably disposed relative to the main body, and a reservoir disposed within the main body for containing a medicament. The device also includes a needle having a distal end for insertion into a patient, and a lumen extending proximally from the distal end, wherein said lumen is fluidly connectable with the reservoir. The device further includes a removable needle cover (114, 400) for selectively covering the distal end of the needle and selectively preventing movement of the actuation button relative to the main body that initiates activation of the device.

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