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    • 3. 发明申请
    • REVERSE-PHASE POLYMERISATION PROCESS INCORPORATING A MICROFLUIDIC DEVICE
    • 合并微流控器件的反相聚合工艺
    • WO2016120819A1
    • 2016-08-04
    • PCT/IB2016/050429
    • 2016-01-28
    • BASF SEBASF (CHINA) COMPANY LIMITED
    • HASCHICK, RobertJELICIC, AleksandraFONSECA ZEPEDA, Gabriela EugeniaRECKMANN, AnnaHOLTZE, ChristianSTRUBEL, Bernd
    • C08F2/32C08F20/56
    • C08F2/32B01J19/0093B01J2219/00833B01J2219/00894C08F20/34C08F120/34
    • A reverse-phase suspension polymerization process for the manufacture of polymer beads comprising forming aqueous monomer beads of an aqueous solution comprising water-soluble ethylenically unsaturated monomer or monomer blend, polymerizing the monomer or monomer blend to form polymer beads while suspended in a non-aqueous liquid, and recovering polymer beads, comprises providing a volume of non-aqueous liquid (2) in a vessel (1), where the volume of non-aqueous liquid extends between at least one polymer bead discharge point(3) and at least one monomer feed point (4), generating monomer micro-volumes in at least one microfluidic device (5), said monomer micro-volumes being separated by none-aqueous liquid in at least one first microfluidic channel (6), feeding the monomer micro-volumes through the at least one first microfluidic channel (6) towards the at least one monomer feed point (4) at which the monomer micro-volumes enter into or onto the volume (2) of non-aqueous liquid and form aqueous monomer droplet, allowing the aqueous monomer droplets to flow towards the polymer bead discharge point, initiating polymerization of the aqueous monomer droplets to form polymerizing beads.
    • 一种用于制备聚合物珠粒的反相悬浮聚合方法,其包括形成包含水溶性烯属不饱和单体或单体共混物的水溶液的含水单体珠粒,将单体或单体共混物聚合以形成聚合物珠粒,同时悬浮在非水性 液体和回收的聚合物珠粒包括在容器(1)中提供一定体积的非水性液体(2),其中非水性液体的体积在至少一个聚合物珠粒排出点(3)和至少一个 单体进料点(4),在至少一个微流体装置(5)中产生单体微量,所述单体微量体在至少一个第一微流体通道(6)中由非水性液体分离, 通过至少一个第一微流体通道(6)的体积朝向至少一个单体进料点(4),在该单体进料点处,单体微量体积进入非水性液体的体积(2)或其上 m含水单体液滴,使含水单体液滴流向聚合物珠粒排放点,引发含水单体液滴的聚合形成聚合珠粒。