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    • 4. 发明申请
    • DESATURASES AND METHODS FOR PRODUCING POLYUNSATURATED FATTY ACIDS IN TRANSGENIC ORGANISMS
    • 去饱和酶和过程在转基因生物生产多不饱和脂肪酸
    • WO2009016202A3
    • 2009-06-18
    • PCT/EP2008059999
    • 2008-07-30
    • BASF PLANT SCIENCE GMBHBAUER JOERGSENGER TORALF
    • BAUER JOERGSENGER TORALF
    • C12Q1/68C12N15/82
    • C12N15/8247C12N9/0083
    • The invention relates to polynucleotides from Helobdella robusta, Laccaria bicolor, Lottia gigantea, Microcoleus chthonoplastes, Monosiga brevicollis, Mycosphaerella fijiensis, Mycospaerella graminicola, Naegleria gruben, Nectria haematococca, Nematostella vectensis, Phycomyces blakesleeanus, Trichoderma resii, Physcomitrella patens, Postia placenta, Selaginella moellendorffii and Microdochium nivale that code desaturases and that can be used for the recombinant production of polyunsaturated fatty acids. The invention also relates to the vectors, host cells and transgenic non-human organisms that contain said inventive polynucleotides, and also the polypeptides coded by said polynucleotides. The invention further relates to antibodies against the inventive polypeptides. Finally, the invention relates to production methods for the polyunsaturated fatty acids and for oil, lipid and fatty acid compositions and to the use thereof as medicments, cosmetics, food, animal food, preferably fish food or food supplements.
    • 本发明涉及Helobdella罗布斯塔,双色蜡蘑,Lottia巨,Microcoleus chthonoplastes,Monosiga brevicollis,斐济球腔菌,Mycospaerella蛛,福氏耐格里坑,Nectria haematococca,Nematostella vectensis,须霉属blakesleeanus,木霉属resii,小立碗藓,Postia胎盘,江南卷柏的多核苷酸 和微结节nivale编码去饱和酶和可用于重组生产多不饱和脂肪酸。 此外,本发明涉及载体,宿主细胞和包含本发明的转基因非人生物的多核苷酸,以及由所述多核苷酸的多肽编码的蛋白质。 本发明还涉及抗体与本发明的多肽。 最后,本发明涉及一种制造方法,所述多不饱和脂肪酸和油,脂类和脂肪酸组合物和它们作为药物,化妆品,食品,饲料,优选鱼饲料或食品补充剂。