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    • 4. 发明申请
    • DICYANO ALKANOIC ACID AMIDES FOR COMBATING ANIMAL PESTS
    • DICYANO ALKANOIC ACIDES用于组合动物乳制品
    • WO2007014899A1
    • 2007-02-08
    • PCT/EP2006/064728
    • 2006-07-27
    • BASF AKTIENGESELLSCHAFTHOFMANN, MichaelBASTIAANS, Henricus, Maria, MartinusLANGEWALD, JürgenOLOUMI-SADEGHI, HassanCULBERTSON, Deborah, L.
    • HOFMANN, MichaelBASTIAANS, Henricus, Maria, MartinusLANGEWALD, JürgenOLOUMI-SADEGHI, HassanCULBERTSON, Deborah, L.
    • A01N37/34C07C255/19C07C253/30
    • A01N37/34C07C255/19C07C255/20C07C255/21C07C317/44
    • Dicyano alkanoic acid amides of formula (I), wherein R 1 is H, alkyl, haloalkyl, alkenyl, haloalkenyl, alkynyl, or haloalkynyl; R 2 is H, CN, alkyl, haloalkyl, alkenyl, haloalkenyl, alkynyl, haloalkynyl, cycloalkyl, halocycloalkyl, alkoxy, or haloalkoxy; R 3 and R 4 are H, alkyl, haloalkyl, alkenyl, haloalkenyl, alkynyl, haloalkynyl, cycloalkyl, halocycloalkyl, cycloalkenyl, halocycloalkenyl, or R 3 and R 4 together can be alkylene, haloalkylene, alkenylene or haloalkenylene; X is O or S; R 5 and R 6 are H, alkyl, optionally substituted with 1 to 3 groups CN, NO 2 , OH, NR 7 R 8 , alkoxy, haloalkoxy, alkylthio, haloalkylthio, cycloalkyl, halocycloalkyl and optionally substituted phenyl; or haloalkyl, cycloalkyl, halocycloalkyl, alkenyl, haloalkenyl, alkynyl, haloalkynyl, alkylsulfinyl, haloalkylsulfinyl, alkylsulfonyl, haloalkylsulfonyl, NR 7 R 8 , alkoxycarbonyl, haloalkoxycarbonyl, alkenyloxycarbonyl, haloalkenyloxycarbonyl, alkylcarbonyl, haloalkylcarbonyl, R 7 R 8 N-C(=O)-, phenylcarbonyl, benzylcarbonyl or phenyl wherein phenylcarbonyl, benzylcarbonyl and phenyl are optionally substituted; or R 5 and R 6 are a saturated, partially unsaturated or unsaturated 5- to 6-membered heterocyclic radical which may contain 1 to 4 heteroatoms selected from oxygen, nitrogen and sulfur and which radical may be bonded via a carbonyl (C(=O)) linkage, and which radical is optionally substituted; R 7 , R 8 are H, alkyl, haloalkyl, alkylcarbonyl, haloalkylcarbonyl, benzyl, phenyl, phenylcarbonyl, alkylsulfonyl, or haloalkylsulfonyl; or the enantiomers or diastereomers or salts thereof, processes for the preparation of compounds of formula (I), use of compounds of formula (I) for combating insects, acarids, or nematodes, and a method for treating, controlling, preventing or protecting animals against infestation or infection by parasites using compounds of formula (I).
    • 式(I)的二氰基链烷酸酰胺,其中R 1是H,烷基,卤代烷基,烯基,卤代烯基,炔基或卤代炔基; R 2是H,CN,烷基,卤代烷基,烯基,卤代烯基,炔基,卤代炔基,环烷基,卤代环烷基,烷氧基或卤代烷氧基。 R 3和R 4是H,烷基,卤代烷基,烯基,卤代烯基,炔基,卤代炔基,环烷基,卤代环烷基,环烯基,卤代环烯基或R 3, SO 2和R 4一起可以是亚烷基,卤代亚烷基,亚烯基或卤代亚烯基; X是O或S; R 5和R 6是H,烷基,任选被1至3个基团CN,NO 2,OH,NR 7取代 烷氧基,卤代烷氧基,烷硫基,卤代烷硫基,环烷基,卤代环烷基和任意取代的苯基; 或卤代烷基,环烷基,卤代环烷基,烯基,卤代烯基,炔基,卤代炔基,烷基亚磺酰基,卤代烷基亚磺酰基,烷基磺酰基,卤代烷基磺酰基,NR 8 R 8,烷氧基羰基,卤代烷氧基羰基,烯氧基羰基,卤代链烯氧基羰基, 烷基羰基,卤代烷基羰基,R 7 R 8 NC(= O) - ,苯基羰基,苄基羰基或苯基,其中苯基羰基,苄基羰基和苯基任选被取代; 或R 5和R 6是饱和的,部分不饱和的或不饱和的5至6元杂环基,其可以含有1至4个选自氧,氮和硫的杂原子 并且该基团可以通过羰基(C(= O))键键合,并且该基团任选被取代; R 7,R 8是H,烷基,卤代烷基,烷基羰基,卤代烷基羰基,苄基,苯基,苯基羰基,烷基磺酰基或卤代烷基磺酰基; 或其对映体或非对映异构体或其盐,式(I)化合物的制备方法,式(I)化合物用于防治昆虫,螨虫或线虫的用途,以及用于治疗,控制,预防或保护动物的方法 使用式(I)化合物对寄生虫的感染或感染。