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    • 2. 发明申请
    • O-CARBOXYMETHYL OXIME ETHER COMPOUNDS FOR COMBATING ARTHROPOD PESTS
    • 用于组合牙周病的O-羧甲氧基醚化合物
    • WO2007118896A1
    • 2007-10-25
    • PCT/EP2007/053803
    • 2007-04-18
    • BASF AKTIENGESELLSCHAFTHOFMANN, MichaelGROSS, SteffenLANGEWALD, JürgenCULBERTSON, Deborah L.BRAUN, Franz-JosefKUHN, David G.OLOUMI-SADEGHI, Hassan
    • HOFMANN, MichaelGROSS, SteffenLANGEWALD, JürgenCULBERTSON, Deborah L.BRAUN, Franz-JosefKUHN, David G.OLOUMI-SADEGHI, Hassan
    • A01N33/24C07D333/58A01N43/08A01N43/10C07C251/60C07D307/81
    • C07C251/60A01N37/26C07D307/81C07D333/58
    • The present invention relates to new O-carboxymethyl oxime ether compounds which are useful for combating arthropod pests, in particular insects or arachnids. This object is achieved by compounds of formula (I) as defined below and by the agriculturally or veterinably acceptable salts thereof. The invention also relates to a method for combating arthropod pests. In formula (I) ..... is absent or a covalent bond; k is 0, 1, 2, 3 or 4; Cy is a 5- or 6-membered carbocyclic radical or a heterocyclic radical with 1, 2, 3 or 4 heteroatoms which are selected, from O, N and S; R a is inter alia halogen, cyano, nitro, hydroxy, C 1 -C 10 -alkyl, C 1 -C 10 -haloalkyl, C 1 -C 10 -alkoxy, (C 1 -C 10 -alkyl)carbonyl, NR 7 R 8 , CO-NR 7 R 8 and phenoxy, which may be unsubstituted or may carry 1, 2, 3, 4 or 5 substituents, or two vicinal radicals R a together may also be a bivalent radical, thereby forming a 5- to 7-membered fused heterocycle; R 1 , R 2 and R 3 are inter alia hydrogen, C 1 -C 10 -alkyl, C 1 -C 10 -haloalkyl, C 3 -C 10 -cycloalkyl, C 2 -C 10 -alkenyl, cyano, nitro, hydroxy, C 1 -C 10 -alkoxy, phenyl and pyridyl, wherein the aromatic ring of the 2 last mentioned radicals may be unsubstituted or may carry 1, 2, 3, 4 or substituents; R 4 is inter alia hydrogen, halogen, cyano, nitro, hydroxy, C 1 -C 10 -alkyl, C 1 -C 10 -haloalkyl, C 3 -C 10 -cylcoalkyl, C 2 -C 10 -alkenyl, C 1 -C 10 -alkoxy, (C 1 -C 10 -alkyl)carbonyl, NR 17 R 18 , CO-NR 17 R 18 or phenoxy, which may be unsubstituted or may carry 1, 2, 3, 4 or 5 substituents R e ; or if Cy is phenyl, R 2 and R 4 together can also form a bivalent radical Z, which is selected inter alia from -O-, -S-, -N(R b1 )-, -O-C(O)-, -O-CH(R b2 )-, -C(O)-N(R b3 )-, -C(R b5 )=N-; R 5a is inter alia hydrogen, halogen, cyano, nitro, C 1 -C 10 - alkyl, C 1 -C 10 -haloalkyl, (C 1 -C 4 -alkoxy)-C 1 -C 4 -alkyl, C 3 -C 10 -cylcoalkyl, C 2 -C 10 -alkenyl, C 1 -C 10 - alkoxy, pyridyl, phenyl, benzyl and phenoxy, wherein the aromatic ring of the 6 last mentioned radicals may be unsubstituted or may carry 1, 2, 3, 4 or substituents R f ; R 5b is hydrogen, halogen, C 1 -C 4 -alkyl or C 1 -C 4 -alkoxy; or R 5a and R 5b together can also form a bivalent radical Y; R 6 is inter alia hydrogen, C 1 -C 10 -alkyl, C 1 -C 10 -haloalkyl, C 3 -C 10 -cycloalkyl, C 1 -C 4 -alkoxy-C 1 -C 10 -alkyl, benzyl and hetaryl-C 1 -C 4 -alkyl wherein the aromatic ring of the 2 last mentioned radicals may be unsubstituted or may carry 1, 2, 3, 4 or substituents R h .
    • 本发明涉及新的O-羧甲基肟醚化合物,其可用于防治节肢动物害虫,特别是昆虫或蛛形纲虫。 该目的通过如下定义的式(I)化合物和其农业上或可兽医学上可接受的盐来实现。 本发明还涉及一种防治节肢动物害虫的方法。 式(I)中不存在或共价键; k为0,1,2,3或4; Cy是选自O,N和S的5或6元碳环基或具有1,2,3或4个杂原子的杂环基; 卤素,氰基,硝基,羟基,C 1 -C 10 - 烷基,C 1〜 C 1 -C 10 - 卤代烷基,C 1 -C 10 - 烷氧基,(C 1 -C 3 - 亚烷基) C 10 -C 10 - 烷基)羰基,NR 7 R 8,CO-NR 7 R 8, 和苯氧基,其可以是未取代的或可以带有1,2,3,4或5个取代基,或两个连环基R a一起也可以是二价基团,从而形成5-至7- 元稠合杂环; R 1,R 2和R 3特别是氢,C 1 -C 10烷基, C 1 -C 10烷基,C 1 -C 10 - 卤代烷基,C 3 -C 10 - 环烷基,C 1 -C 10 - C 2 -C 10 - 烯基,氰基,硝基,羟基,C 1 -C 10 - 烷氧基,C 1 -C 10 - 苯基和吡啶基,其中最后提到的2个基团的芳环可以是未取代的或可以带有1,2,3,4或取代基; R 4尤其是氢,卤素,氰基,硝基,羟基,C 1 -C 10 - 烷基,C 1 - C 1 -C 10 - 卤代烷基,C 3 -C 10 - 环烷基,C 2 -C 3 - C 1 -C 10烷基,C 1 -C 10 - 烷氧基,(C 1 -C 10 - C 1-4烷基)羰基,NR 17 R 18,CO-NR 17 R 18或苯氧基,其中 可以是未取代的或可以携带1,2,3,4或5个取代基R e; 或者如果Cy是苯基,R 2和R 4一起也可以形成二价基团Z,其特别是从-O - , - S - , - N (R b1) - , - OC(O) - , - O-CH(R b2) - , - (O)-N(R b) ) - , - (R b5)= N-; R 5a尤其是氢,卤素,氰基,硝基,C 1 -C 10 - 烷基,C 1〜 C 1 -C 10 - 卤代烷基,(C 1 -C 4 -C 4 - 烷氧基)-C 1 -C C 1-4烷基,C 3 -C 10 - C 1 -C 10烷基,C 2 -C 10 - 烷基,C 3 -C 10 - → - 烯基,C 1 -C 10 - 烷氧基,吡啶基,苯基,苄基和苯氧基,其中最后提到的6个基团的芳环可以是未取代的或可以携带 1,2,3或4或取代基R f; R 5b是氢,卤素,C 1 -C 4 - 烷基或C 1 -C 3 - 4 - 烷氧基; 或R 5a和R 5b一起也可以形成二价基团Y; R 6尤其是氢,C 1 -C 10 - 烷基,C 1 -C 3 - 10个 - 卤代烷基,C 3 -C 10 - 环烷基,C 1 -C 4 - 烷氧基-C 1 -C 10 - 烷基,苄基和杂芳基-C 1 -C 4 - 烷基,其中 最后提到的2个基团的芳环可以是未取代的或可以携带1,2,3,4或取代基R h。
    • 6. 发明申请
    • RESORCINE DERIVATIVES AND THEIR USE AS PESTICIDES
    • WO2007054558A3
    • 2007-05-18
    • PCT/EP2006/068329
    • 2006-11-10
    • BASF AKTIENGESELLSCHAFTPUHL, MichaelKORDES, MarkusPOHLMAN, MatthiasGÖTZ, NorbertRACK, MichaelLANGEWALD, JürgenSCHNEIDER, FelixANSPAUGH, Douglas D.CULBERTSON, Deborah L.OLOUMI-SADEGHI, HassanKUHN, David G.
    • PUHL, MichaelKORDES, MarkusPOHLMAN, MatthiasGÖTZ, NorbertRACK, MichaelLANGEWALD, JürgenSCHNEIDER, FelixANSPAUGH, Douglas D.CULBERTSON, Deborah L.OLOUMI-SADEGHI, HassanKUHN, David G.
    • C07C43/29C07D213/16C07D213/26C07D277/22A01N29/10
    • This invention relates to resorcine derivatives of formula (I) wherein R 1 is phenyl or a 5- to 6-membered heteroaromatic ring which may contain 1 to 3 heteroatoms selected from oxygen, nitrogen and sulfur, wherein phenyl or the heteroaromatic ring may be fused to a ring selected from phenyl and a 5- to 6-membered saturated, partially unsaturated or aromatic heterocyclic ring which may contain 1 to 3 heteroatoms selected from oxygen, nitrogen and sulfur, wherein phenyl or the 5- to 6-membered heteroaromatic ring or the respective fused ring systems may be unsubstituted or substituted by any combination of 1 to 6 optionally substituted groups R 3 , wherein R 3 is halogen, cyano, nitro, hydroxy, mercapto, amino, alkyl, alkenyl, alkynyl, cycloalkyl, cycloalkenyl, haloalkyl, haloalkenyl, haloalkynyl, halocycloalkyl, halocycloalkenyl, alkoxy, alkenyloxy, alkynyloxy, haloalkoxy, haloalkenyloxy, haloalkynyloxy, alkylthio, alkenylthio, alkynylthio, haloalkylthio, haloalkenylthio, haloalkynylthio, alkylamino, alkenylamino, alkynylamino, dialkylamino, dialkenylamino, dialkynylamino, alkyl-alkenylamino, alkyl-alkynylamino, alkenyl- alkynylamino, trialkylsilyl, or phenyl or a 5-to 7-membered saturated or partially unsaturated heterocyclic ring which may contain 1 to 3 heteroatoms selected from oxygen, sulfur and nitrogen or a 5- to 6-membered heteraromatic ring system which may contain 1 to 4 heteroatoms selected from oxygen, nitrogen and sulfur, which phenyl and which heteroaromatic ring may be bonded via an oxygen or a sulfur atom, or -C(=G)R a , -C(=G)OR a , -C(=G)NR a 2 , -C(=G)[N=SR a 2 ], -C(=NOR a )R a , -C(=NOR a )NR a 2 , -C(=NNR a 2 )R a , -OC(=G)-OC(=G)OR a , N=SR a 2 , -NR a C(=G)R a , -N[C(=G)R a ] 2 , - NR a C(=G)OR a , -C(=G)NR a -NR a 2 , -C(=G)NR a -NR a [C(=G)R a ], -NR a -C(=G)NR a 2 , -NR a -NR a C(=G)R a , -NR a -N[C(=G)R a ] 2 , -N[(C=G)R a ]-NR a 2 , -NR a -NR a [(C=G)GR a ], -NR a [(C=G)NR a 2 , -NR a [C=NR a ]R a , -NR a (C=NR a )NR a 2 , -O-NR a 2 , -O-NR a (C=G)R a , - SO 2 NR a 2 , -NR a SO 2 R a , -S(=O)R a , -S(=O) 2 R a , -SO 2 OR a , or -OSO 2 R a , wherein G is oxygen or sulfur and Ra is as defined in the description, R 2 is hydrogen, halogen, cyano, alkyl, haloalkyl, alkenyl, haloalkenyl, alkynyl, haloalkynyl, alkoxy, or haloalkoxy, x is 2, 3, 4, 5, 6, or 7, or the diastereomers, enantiomers, salts or N-oxides thereof, with the proviso that R 1 is not 5-chloro-2,2,-dimethyl-2,3-dihydrobenzo[b]furan-7-yl when R 2 is hydrogen and x is 3 or 4, processes and intermediates for the preparation of compounds I, use of compounds I for combating insects, acarids, or nematodes, and a method for treating, controlling, preventing or protecting animals against infestation or infection by parasites using compounds I.
    • 9. 发明申请
    • DICYANO ALKANOIC ACID AMIDES FOR COMBATING ANIMAL PESTS
    • DICYANO ALKANOIC ACIDES用于组合动物乳制品
    • WO2007014899A1
    • 2007-02-08
    • PCT/EP2006/064728
    • 2006-07-27
    • BASF AKTIENGESELLSCHAFTHOFMANN, MichaelBASTIAANS, Henricus, Maria, MartinusLANGEWALD, JürgenOLOUMI-SADEGHI, HassanCULBERTSON, Deborah, L.
    • HOFMANN, MichaelBASTIAANS, Henricus, Maria, MartinusLANGEWALD, JürgenOLOUMI-SADEGHI, HassanCULBERTSON, Deborah, L.
    • A01N37/34C07C255/19C07C253/30
    • A01N37/34C07C255/19C07C255/20C07C255/21C07C317/44
    • Dicyano alkanoic acid amides of formula (I), wherein R 1 is H, alkyl, haloalkyl, alkenyl, haloalkenyl, alkynyl, or haloalkynyl; R 2 is H, CN, alkyl, haloalkyl, alkenyl, haloalkenyl, alkynyl, haloalkynyl, cycloalkyl, halocycloalkyl, alkoxy, or haloalkoxy; R 3 and R 4 are H, alkyl, haloalkyl, alkenyl, haloalkenyl, alkynyl, haloalkynyl, cycloalkyl, halocycloalkyl, cycloalkenyl, halocycloalkenyl, or R 3 and R 4 together can be alkylene, haloalkylene, alkenylene or haloalkenylene; X is O or S; R 5 and R 6 are H, alkyl, optionally substituted with 1 to 3 groups CN, NO 2 , OH, NR 7 R 8 , alkoxy, haloalkoxy, alkylthio, haloalkylthio, cycloalkyl, halocycloalkyl and optionally substituted phenyl; or haloalkyl, cycloalkyl, halocycloalkyl, alkenyl, haloalkenyl, alkynyl, haloalkynyl, alkylsulfinyl, haloalkylsulfinyl, alkylsulfonyl, haloalkylsulfonyl, NR 7 R 8 , alkoxycarbonyl, haloalkoxycarbonyl, alkenyloxycarbonyl, haloalkenyloxycarbonyl, alkylcarbonyl, haloalkylcarbonyl, R 7 R 8 N-C(=O)-, phenylcarbonyl, benzylcarbonyl or phenyl wherein phenylcarbonyl, benzylcarbonyl and phenyl are optionally substituted; or R 5 and R 6 are a saturated, partially unsaturated or unsaturated 5- to 6-membered heterocyclic radical which may contain 1 to 4 heteroatoms selected from oxygen, nitrogen and sulfur and which radical may be bonded via a carbonyl (C(=O)) linkage, and which radical is optionally substituted; R 7 , R 8 are H, alkyl, haloalkyl, alkylcarbonyl, haloalkylcarbonyl, benzyl, phenyl, phenylcarbonyl, alkylsulfonyl, or haloalkylsulfonyl; or the enantiomers or diastereomers or salts thereof, processes for the preparation of compounds of formula (I), use of compounds of formula (I) for combating insects, acarids, or nematodes, and a method for treating, controlling, preventing or protecting animals against infestation or infection by parasites using compounds of formula (I).
    • 式(I)的二氰基链烷酸酰胺,其中R 1是H,烷基,卤代烷基,烯基,卤代烯基,炔基或卤代炔基; R 2是H,CN,烷基,卤代烷基,烯基,卤代烯基,炔基,卤代炔基,环烷基,卤代环烷基,烷氧基或卤代烷氧基。 R 3和R 4是H,烷基,卤代烷基,烯基,卤代烯基,炔基,卤代炔基,环烷基,卤代环烷基,环烯基,卤代环烯基或R 3, SO 2和R 4一起可以是亚烷基,卤代亚烷基,亚烯基或卤代亚烯基; X是O或S; R 5和R 6是H,烷基,任选被1至3个基团CN,NO 2,OH,NR 7取代 烷氧基,卤代烷氧基,烷硫基,卤代烷硫基,环烷基,卤代环烷基和任意取代的苯基; 或卤代烷基,环烷基,卤代环烷基,烯基,卤代烯基,炔基,卤代炔基,烷基亚磺酰基,卤代烷基亚磺酰基,烷基磺酰基,卤代烷基磺酰基,NR 8 R 8,烷氧基羰基,卤代烷氧基羰基,烯氧基羰基,卤代链烯氧基羰基, 烷基羰基,卤代烷基羰基,R 7 R 8 NC(= O) - ,苯基羰基,苄基羰基或苯基,其中苯基羰基,苄基羰基和苯基任选被取代; 或R 5和R 6是饱和的,部分不饱和的或不饱和的5至6元杂环基,其可以含有1至4个选自氧,氮和硫的杂原子 并且该基团可以通过羰基(C(= O))键键合,并且该基团任选被取代; R 7,R 8是H,烷基,卤代烷基,烷基羰基,卤代烷基羰基,苄基,苯基,苯基羰基,烷基磺酰基或卤代烷基磺酰基; 或其对映体或非对映异构体或其盐,式(I)化合物的制备方法,式(I)化合物用于防治昆虫,螨虫或线虫的用途,以及用于治疗,控制,预防或保护动物的方法 使用式(I)化合物对寄生虫的感染或感染。