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1. 发明申请

WO2004108068A3 4-[4-(4-MORPHOLINO)ANILINO]PYRIMIDINE DERIVATIVES, METHOD FOR PREPARING THEREOF AND ANTIVIRAL PHARMACEUTICAL COMPOSITION COMPRISING THE SAME 审中-公开
标题翻译： 4- [4-（4-吗啉基）苯胺基]吡啶衍生物，其制备方法和包含其的抗病毒药物组合物
公开(公告)号：WO2004108068A3
公开(公告)日：2005-02-17
申请号：PCT/KR2004001297
申请日：2004-06-01
申请人： B & C BIOPHARM CO LTD , KIM JONG-WOO , LEE SANG-WOOK , LEE GEUN-HYUNG , HAN JAE-JIN , PARK SANG-JIN , PARK EUL-YONG , SHIN JOONG-CHUL
发明人： KIM JONG-WOO , LEE SANG-WOOK , LEE GEUN-HYUNG , HAN JAE-JIN , PARK SANG-JIN , PARK EUL-YONG , SHIN JOONG-CHUL
IPC分类号： C07D413/12 , A61K20060101
CPC分类号： C07D239/47
摘要： The present invention relates to 4-[4-(4-morpholino)anilino]pyrimidine derivatives useful as an antiviral agent, and more particularly novel 4-[4-(4-morpholino)anilino]pyrimidine derivatives having an excellent inhibitory effect on replication of Hepatitis C virus (HCV), represented by the following formula I: in which R1 represents C1-C4 straight or branched alkoxy group, -NR2R3 group or 4-(R4)-piperazin-l-yl group; R2 represents hydrogen or C1-C4 straight or branched alkyl group; R3 represents C1-C4 straight or branched alkyl group, C1-C4 straight or branched hydroxyalkyl group, C1-C4 straight or branched alkyl group substituted by C2-C6 straight or branched dialkylamino group or C1-C4 straight or branched alkyl group substituted by heterocyclic ring; R4 represents C1-C4 straight or branched alkoxycarbonylmethyl group, carboxymethyl group or -CH2-CO-NH-R5 group; and R5 represents C1-C4 straight or branched alkyl group, C1-C4 straight or branched hydroxyalkyl group, C3-C6 cycloalkyl group or C1-C4 straight or branched alkyl group substituted by heterocyclic ring; and pharmaceutically acceptable salts thereof, a preparation method thereof, and an antiviral pharmaceutical composition comprising the compound as an effective component. The 4-[4-(4-morpholino)anilino]pyrimidine derivatives according to the present invention have an excellent inhibitory effect on replication of Hepatitis C virus (HCV) and thus can be advantageously used as a therapeutic or prophylactic agent of hepatitis C.
摘要翻译：本发明涉及可用作抗病毒剂的4- [4-（4-吗啉代）苯胺基]嘧啶衍生物，更特别地涉及对复制具有优异抑制作用的更具体的新型4- [4-（4-吗啉代）苯胺基]嘧啶衍生物由下式I表示的丙型肝炎病毒（HCV）：其中R1表示C1-C4直链或支链烷氧基，-NR2R3基或4-（R4） - 哌嗪-1-基; R2表示氢或C1-C4直链或支链烷基; R3表示C1-C4直链或支链烷基，C1-C4直链或支链羟烷基，被C2-C6直链或支链二烷基氨基取代的C1-C4直链或支链烷基或被杂环取代的C1-C4直链或支链烷基环; R4表示C1-C4直链或支链烷氧基羰基甲基，羧甲基或-CH2-CO-NH-R5基团; R5表示C1-C4直链或支链烷基，C1-C4直链或支链羟烷基，C3-C6环烷基或被杂环取代的C1-C4直链或支链烷基; 及其药学上可接受的盐，其制备方法和包含该化合物作为有效成分的抗病毒药物组合物。根据本发明的4- [4-（4-吗啉代）苯胺基]嘧啶衍生物对丙型肝炎病毒（HCV）的复制具有优异的抑制作用，因此可有利地用作丙型肝炎的治疗或预防剂。

2. 发明申请

WO2004108719A9 2-[2-(4-MORPHOLINO)ETHYLAMINO]PYRIDINE DERIVATIVES, METHOD FOR PREPARING THEREOF AND ANTIVIRAL PHARMACEUTICAL COMPOSITION COMPRISING THE SAME 审中-公开
标题翻译： 2- [2-（4-吗啉基）乙基氨基]吡啶衍生物，其制备方法和包含其的抗病毒药物组合物
公开(公告)号：WO2004108719A9
公开(公告)日：2005-07-28
申请号：PCT/KR2004001298
申请日：2004-06-01
申请人： B & C BIOPHARM CO LTD , KIM JONG-WOO , LEE SANG-WOOK , LEE GEUN-HYUNG , HAN JAE-JIN , PARK SANG-JIN , PARK EUL-YONG , SHIN JOONG-CHUL
发明人： KIM JONG-WOO , LEE SANG-WOOK , LEE GEUN-HYUNG , HAN JAE-JIN , PARK SANG-JIN , PARK EUL-YONG , SHIN JOONG-CHUL
IPC分类号： C07D413/14 , C07D213/74
CPC分类号： C07D213/74
摘要： The present invention relates to 2-[2-(4-morpholino)ethylamino]pyridine derivatives useful as an antiviral agent, and more particularly novel 2-[2-(4-morpholino)ethylamino]pyridine derivatives having an excellent inhibitory effect on replication of Hepatitis C virus (HCV), represented by the following formula (I) in which R1 and R2 represent respectively C1-C4 straight or branched alkyl group, C1-C4 straight or branched alkoxy group, methylthio group, trifluoromethyl group, halogen atom, or hydrogen atom, and X represents oxygen atom or sulfur atom; and pharmaceutically acceptable salts thereof, a preparation method thereof, and an antiviral pharmaceutical composition comprising the compound as an effective component. The 2-[2-(4-morpholino)ethylamino]pyridine derivatives according to the present invention have an excellent inhibitory effect on replication of Hepatitis C virus (HCV) and thus can be advantageously used as a therapeutic or prophylactic agent of hepatitis C.
摘要翻译：本发明涉及可用作抗病毒剂的2- [2-（4-吗啉代）乙氨基]吡啶衍生物，更特别地涉及对复制具有优异抑制作用的更具体的新型2- [2-（4-吗啉代）乙氨基]吡啶衍生物由下式（I）表示的丙烯酸类病毒（HCV），其中R1和R2分别表示C1-C4直链或支链烷基，C1-C4直链或支链烷氧基，甲硫基，三氟甲基，卤素原子，或氢原子，X表示氧原子或硫原子; 及其药学上可接受的盐，其制备方法和包含该化合物作为有效成分的抗病毒药物组合物。根据本发明的2- [2-（4-吗啉代）乙氨基]吡啶衍生物对丙型肝炎病毒（HCV）的复制具有优异的抑制作用，因此可有利地用作丙型肝炎的治疗或预防剂。

3. 发明申请

WO0178648A3 6-METHYLNICOTINAMIDE DERIVATIVES AS ANTIVIRAL AGENTS 审中-公开
标题翻译： 6-甲基吗啉衍生物作为抗病毒剂
公开(公告)号：WO0178648A3
公开(公告)日：2003-12-18
申请号：PCT/KR0100613
申请日：2001-04-13
申请人： DONG WHA PHARM IND CO LTD , YOON SUNG-JUNE , LEE SANG-WOOK , LEE JIN-SOO , KIM NAM-DOO , LEE GEUN-HYUNG , LEE HAK-DONG , KIM JONG-WOO , PARK SANG-JIN , PARK HEE-JEONG
发明人： YOON SUNG-JUNE , LEE SANG-WOOK , LEE JIN-SOO , KIM NAM-DOO , LEE GEUN-HYUNG , LEE HAK-DONG , KIM JONG-WOO , PARK SANG-JIN , PARK HEE-JEONG
IPC分类号： A61P31/18 , C07D213/82 , C07D401/12 , C07D401/14 , C07D521/00
CPC分类号： C07D213/82 , C07D231/12 , C07D233/56 , C07D249/08 , C07D401/12 , C07D401/14
摘要： The present invention relates to novel 6-methylnicotinamide derivatives and their pharmaceutically acceptable salts, the process for preparing them, and the pharmaceutical compositions containing said compounds as active ingredients. The 6-methylnicotinamide derivatives of the present invention exhibit their inhibitory activity against the proliferation of human immunodeficiency virus (HIV) as well as hepatitis B virus (HBV) and Hepatitis C virus (HCV), such that they can be used for hepatitis B, hepatitis C and acquired immune deficiency syndrome (AIDS).
摘要翻译：本发明涉及新的6-甲基烟酰胺衍生物及其药学上可接受的盐，其制备方法和含有所述化合物作为活性成分的药物组合物。本发明的6-甲基烟酰胺衍生物对人类免疫缺陷病毒（HIV）以及乙型肝炎病毒（HBV）和丙型肝炎病毒（HCV）的增殖具有抑制活性，从而可用于乙型肝炎，丙型肝炎和获得性免疫缺陷综合征（AIDS）。

4. 发明申请

WO2004086215A8 LIGHT PEN 审中-公开
标题翻译：光笔
公开(公告)号：WO2004086215A8
公开(公告)日：2005-02-24
申请号：PCT/KR2004000639
申请日：2004-03-24
申请人： SAMSUNG ELECTRONICS CO LTD , CHO JONG-WHAN , PARK SANG-JIN , PARK WON-SANG , UH KEE-HAN , KIM HYUNG-GUEL , JUNG JAE-HOON
发明人： CHO JONG-WHAN , PARK SANG-JIN , PARK WON-SANG , UH KEE-HAN , KIM HYUNG-GUEL , JUNG JAE-HOON
IPC分类号： G06F3/0354 , G06F3/033 , G06K11/08 , G09F9/35 , G09G3/36
CPC分类号： G06F3/03545
摘要： A photo detective LCD device includes a light pen (100). The light pen includes a body (110), a driving pulse generating module (135) and a light generating module (140). The body has a pen shape, and an end of the body includes an opening (112) through which light exits. The driving pulse generating module is disposed in the body and generates first and second driving power pulses having first and second frequencies, respectively. The light generating module generates first and second light in response to the first and second driving power pulses, respectively. The first and second light flickers in a third frequency and a fourth frequency, respectively. The power consumption is reduced, and the brightness of sensing light is enhanced. The light pen generates light having at least two different frequencies, and the display device recognizes light generated from the light pen effectively. Therefore, the display device may operate without failure.
摘要翻译：照相检测LCD装置包括光笔（100）。光笔包括主体（110），驱动脉冲产生模块（135）和发光模块（140）。本体具有笔形，并且本体的端部包括光离开的开口（112）。驱动脉冲发生模块设置在主体中，分别产生具有第一和第二频率的第一和第二驱动功率脉冲。光产生模块分别响应于第一和第二驱动功率脉冲产生第一和第二光。第一和第二光分别以第三频率和第四频率闪烁。功耗降低，感光的亮度提高。光笔产生具有至少两个不同频率的光，并且显示装置有效地识别从光笔产生的光。因此，显示装置可以无故障地运行。

5. 发明申请

WO2004086215A3 LIGHT PEN 审中-公开
标题翻译：光笔
公开(公告)号：WO2004086215A3
公开(公告)日：2004-12-23
申请号：PCT/KR2004000639
申请日：2004-03-24
申请人： SAMSUNG ELECTRONICS CO LTD , CHO JONG-WHAN , PARK SANG-JIN , PARK WON-SANG , UH KEE-HAN , KIM HYUNG-GUEL , JUNG JAE-HOON
发明人： CHO JONG-WHAN , PARK SANG-JIN , PARK WON-SANG , UH KEE-HAN , KIM HYUNG-GUEL , JUNG JAE-HOON
IPC分类号： G06F3/0354 , G06F3/033 , G06K11/08 , G09F9/35 , G09G3/36
CPC分类号： G06F3/03545
摘要： A photo detective LCD device includes a light pen (100). The light pen includes a body (110), a driving pulse generating module (135) and a light generating module (140). The body has a pen shape, and an end of the body includes an opening (112) through which light exits. The driving pulse generating module is disposed in the body and generates first and second driving power pulses having first and second frequencies, respectively. The light generating module generates first and second light in response to the first and second driving power pulses, respectively. The first and second light flickers in a third frequency and a fourth frequency, respectively. The power consumption is reduced, and the brightness of sensing light is enhanced. The light pen generates light having at least two different frequencies, and the display device recognizes light generated from the light pen effectively. Therefore, the display device may operate without failure.
摘要翻译：照相检测LCD装置包括光笔（100）。光笔包括主体（110），驱动脉冲产生模块（135）和发光模块（140）。本体具有笔形，并且本体的端部包括光离开的开口（112）。驱动脉冲发生模块设置在主体中，分别产生具有第一和第二频率的第一和第二驱动功率脉冲。光产生模块分别响应于第一和第二驱动功率脉冲产生第一和第二光。第一和第二光分别以第三频率和第四频率闪烁。功耗降低，感光的亮度提高。光笔产生具有至少两个不同频率的光，并且显示装置有效地识别从光笔产生的光。因此，显示装置可以无故障地运行。

6. 实用新型

KR880001243Y1 자동세탁기의 기름자동 배출장치. 失效
公开(公告)号：KR880001243Y1
公开(公告)日：1988-04-02
申请号：KR850002270
申请日：1985-03-05
申请人： PARK SANG JIN
发明人： PARK SANG-JIN
IPC分类号： D06F43/00

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