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1. 发明授权

US06327493B1 Light scanning devices of a water-tight structure to be inserted into a body cavity to obtain optical information on inside of a biological tissue 有权
标题翻译：将要插入体腔的水密结构的光扫描装置获得生物组织内部的光学信息
公开(公告)号：US06327493B1
公开(公告)日：2001-12-04
申请号：US09141572
申请日：1998-08-27
申请人： Takeshi Ozawa , Mamoru Kaneko , Akihiro Horii , Atsushi Okawa , Hiroki Hibino , Hiroyuki Sangu , Hitoshi Ueno , Hitoshi Mizuno , Jun Hiroya , Katsuichi Imaizumi , Hidemichi Aoki , Masahiro Ohno , Eiji Yasuda , Yoshinao Oaki , Kenji Yoshino , Sakae Takehana , Isami Hirao , Takefumi Uesugi , Toshimasa Kawai
发明人： Takeshi Ozawa , Mamoru Kaneko , Akihiro Horii , Atsushi Okawa , Hiroki Hibino , Hiroyuki Sangu , Hitoshi Ueno , Hitoshi Mizuno , Jun Hiroya , Katsuichi Imaizumi , Hidemichi Aoki , Masahiro Ohno , Eiji Yasuda , Yoshinao Oaki , Kenji Yoshino , Sakae Takehana , Isami Hirao , Takefumi Uesugi , Toshimasa Kawai
IPC分类号： A61B600
CPC分类号： A61B5/0073 , A61B5/0066 , A61B5/0068
摘要： A light scanning device has a tip structure which includes a light scanning part connected to a light source, and which is insertable into a body cavity and is formed so as to be water-tight. A controlling part controls the light scan through the tip structure, and the tip structure and the controlling part are also connected to each other in a water-tight manner by a slender tube through which a plurality of electrical cables pass. An electric connector is fixed with the proximal end portion of the tube in a water-tight manner, and is electrically connectable so as to be water-tight with and removable from this controlling part.
摘要翻译：光扫描装置具有尖端结构，该尖端结构包括连接到光源的光扫描部分，并且其可插入体腔中并且被形成为防水的。控制部分通过尖端结构控制光扫描，并且尖端结构和控制部分也通过多根电缆通过的细长管以水密的方式彼此连接。电连接器以水密方式与管的近端部分固定，并且可电连接以便与该控制部件具有防水性和可拆卸性。

2. 发明授权

US07129472B1 Optical scanning probe system 有权
标题翻译：光学扫描探针系统
公开(公告)号：US07129472B1
公开(公告)日：2006-10-31
申请号：US09857614
申请日：2000-10-04
申请人： Atsushi Okawa , Hiroki Hibino , Hiroyuki Sangu
发明人： Atsushi Okawa , Hiroki Hibino , Hiroyuki Sangu
IPC分类号： H01J5/16 , G02B21/00 , G02B26/08
CPC分类号： A61B1/0008 , A61B1/00059 , A61B1/00165 , A61B1/00172 , A61B1/04 , A61B5/0062 , A61B5/0068 , A61B5/0084 , A61B2562/0242 , G02B6/32 , G02B6/4226 , G02B23/2423 , G02B26/0875 , G02B26/101 , G02B26/103 , H04N2005/2255
摘要： An identification circuit (131) recognizes optical probes (112A, 112B) of different scanning types that are connected to a light source unit (113) and a control device (114), the frequency of the drive signal of a control circuit (130) for driving a scanner inside the optical probe is varied by this recognition signal, corresponding drive signals are applied to the optical probes connected, the scanner of each probe is scanned, and two-dimensional optical information is imaged by an imaging device (115) and displayed on a monitor (116).
摘要翻译：识别电路（131）识别连接到光源单元（113）和控制装置（114）的不同扫描类型的光学探针（112A，112B），控制电路的驱动信号的频率通过该识别信号来改变用于驱动光学探头内的扫描仪的光学元件130），将相应的驱动信号施加到连接的光学探针，扫描每个探针的扫描器，并且通过成像装置（115）对二维光学信息进行成像）并显示在监视器（116）上。

3. 发明授权

US6069698A Optical imaging apparatus which radiates a low coherence light beam onto a test object, receives optical information from light scattered by the object, and constructs therefrom a cross-sectional image of the object 有权
标题翻译：将低相干光束照射到测试对象上的光学成像设备从由物体散射的光接收光学信息，并由其构造物体的横截面图像
公开(公告)号：US6069698A
公开(公告)日：2000-05-30
申请号：US141430
申请日：1998-08-27
申请人： Takeshi Ozawa , Mamoru Kaneko , Akihiro Horii , Hitoshi Ueno , Sakae Takehana , Hiroyuki Sangu , Isami Hirao , Hitoshi Mizuno , Toshimasa Kawai , Hiroki Hibino , Hideyuki Adachi , Hironobu Takizawa , Takefumi Uesugi , Masahiro Ohno , Hidemichi Aoki , Jun Hiroya , Katsuichi Imaizumi , Eiji Yasuda , Yoshinao Oaki , Kenji Yoshino
发明人： Takeshi Ozawa , Mamoru Kaneko , Akihiro Horii , Hitoshi Ueno , Sakae Takehana , Hiroyuki Sangu , Isami Hirao , Hitoshi Mizuno , Toshimasa Kawai , Hiroki Hibino , Hideyuki Adachi , Hironobu Takizawa , Takefumi Uesugi , Masahiro Ohno , Hidemichi Aoki , Jun Hiroya , Katsuichi Imaizumi , Eiji Yasuda , Yoshinao Oaki , Kenji Yoshino
IPC分类号： A61B5/00 , G01B9/02
CPC分类号： G01B9/02069 , A61B5/0062 , A61B5/0066 , A61B5/0084 , G01B9/0205 , G01B9/02064 , G01B9/02091 , A61B5/0086 , G01B2290/35 , G01B2290/65
摘要： A low coherence beam emitted by a low coherence light source is split into two portions. One portion is transmitted from the outward end of a first single mode fiber via a detachable connector to a beam scanning probe, and then to a biological tissue; and the other is transmitted from an optical coupler placed midway along the light path via a second single mode fiber to a light path modifier. The light path modifier includes a galvanometer mirror to modify the light path length in accordance with a scan range, and a uniaxial stage to adjust the light path length to absorb the variation in lengths of different beam scanning probes. The light path is adjusted by the uniaxial stage such that the beam interference is detected for the scan range, to ensure stable acquisition of tomographic images.
摘要翻译：由低相干光源发射的低相干光束被分成两部分。一部分从第一单模光纤的外端通过可拆卸连接器传输到光束扫描探针，然后传输到生物组织; 另一个从位于光路的中途的光耦合器经由第二单模光纤传输到光路修正器。光路修正器包括根据扫描范围修改光路长度的电流计镜，以及调整光路长度以吸收不同束扫描探针的长度变化的单轴阶段。通过单轴阶段调整光路，使得在扫描范围内检测光束干涉，以确保断层图像的稳定采集。

4. 发明申请

US20090181862A1 PROTEIN CHIP AND PRODUCTION METHOD THEREOF 有权
标题翻译：蛋白芯片及其生产方法
公开(公告)号：US20090181862A1
公开(公告)日：2009-07-16
申请号：US11972820
申请日：2008-01-11
申请人： Chandra Sekar Ramanujan , Koji Sumitomo , Maurits R.R. de Planque , Hiroki Hibino , John F. Ryan , Keiichi Torimitsu
发明人： Chandra Sekar Ramanujan , Koji Sumitomo , Maurits R.R. de Planque , Hiroki Hibino , John F. Ryan , Keiichi Torimitsu
IPC分类号： C40B40/10 , C40B50/18
CPC分类号： C40B60/12 , B01J2219/00527 , B01J2219/00576 , B01J2219/00596 , B01J2219/00605 , B01J2219/00612 , B01J2219/00617 , B01J2219/00626 , B01J2219/0063 , B01J2219/00632 , B01J2219/00648 , B01J2219/00659 , B01J2219/00664 , B01J2219/00677 , B82Y30/00 , C40B50/18 , C40B80/00
摘要： A protein chip including at least a substrate having a plurality of steps which are regularly arranged on one surface thereof; a plurality of metallic microstructures arranged in the steps; and a lipid vesicle in which an outer surface thereof is modified by a functional group and a protein is present in a lipid bilayer thereof. The metallic microstructures and the lipid vesicle are bound via the functional group to provide the protein on the substrate.
摘要翻译：一种蛋白质芯片，其至少包括具有规则地布置在其一个表面上的多个台阶的基板; 布置在所述台阶中的多个金属微结构; 脂质囊泡，其外表面被官能团修饰，蛋白质存在于脂质双层中。金属微结构和脂质囊泡通过官能团结合以在基底上提供蛋白质。

5. 发明授权

US5467911A Surgical device for stapling and fastening body tissues 失效
标题翻译：用于缝合和紧固身体组织的手术装置
公开(公告)号：US5467911A
公开(公告)日：1995-11-21
申请号：US231241
申请日：1994-04-22
申请人： Minoru Tsuruta , Toshihiko Suzuta , Akio Nakada , Seiji Kuramoto , Hiroki Hibino , Shiro Bito , Akito Mukaizawa
发明人： Minoru Tsuruta , Toshihiko Suzuta , Akio Nakada , Seiji Kuramoto , Hiroki Hibino , Shiro Bito , Akito Mukaizawa
IPC分类号： A61B17/00 , A61B17/068 , A61B17/072 , A61B17/115
CPC分类号： A61B17/115 , A61B17/0682 , A61B17/0684 , A61B17/07207 , A61B17/1285 , A61B17/1155 , A61B2017/00464 , A61B2017/00734
摘要： Disclosed herein is a surgical device for applying surgical fasteners to body tissues in order to fasten the body tissues together. The device comprises an operation section having a housing having an inner space completely sealed from the outside, drive elements electrically driven and arranged in the inner space of the operation section, an insertion section including a housing which has a first end portion containing the fasteners and having an opening through which the fasteners are to be applied, and a second end portion removably coupled to the housing of the operation section, fastener-applying elements located in the housing of the insertion section, for applying the fasteners from the opening to body tissues, and force-transmitting elements for transmitting drive force from the drive elements to the fastener-applying elements.
摘要翻译：本文公开了一种用于将外科紧固件应用于身体组织以便将身体组织紧固在一起的外科装置。该装置包括具有壳体的操作部分，其具有与外部完全密封的内部空间，电驱动并布置在操作部分的内部空间中的驱动元件，包括壳体的插入部分，该壳体具有容纳紧固件的第一端部，具有开口，紧固件将通过该开口，以及可移除地联接到操作部分的壳体的第二端部，位于插入部分的壳体中的紧固件施加元件，用于将紧固件从开口施加到身体组织以及用于将驱动力从驱动元件传递到紧固件施加元件的力传递元件。

6. 发明授权

US5065741A Extracoporeal ultrasonic lithotripter with a variable focus 失效
标题翻译：具有可变焦点的超声波碎石机
公开(公告)号：US5065741A
公开(公告)日：1991-11-19
申请号：US639922
申请日：1991-01-09
申请人： Naoki Uchiyama , Takashi Tsukaya , Kouichiro Ishihara , Sakae Takehana , Tetsumaru Kubota , Syuichi Takayama , Akira Taniguchi , Nobuhiko Watanabe , Naomi Sekino , Hiroki Hibino , Masaaki Hayashi
发明人： Naoki Uchiyama , Takashi Tsukaya , Kouichiro Ishihara , Sakae Takehana , Tetsumaru Kubota , Syuichi Takayama , Akira Taniguchi , Nobuhiko Watanabe , Naomi Sekino , Hiroki Hibino , Masaaki Hayashi
IPC分类号： A61B17/00 , A61B17/22
CPC分类号： A61B17/2255 , A61B17/2256 , A61B2017/00699
摘要： A therapeutical apparatus includes a measuring apparatus including a probe which generates an X-ray or ultrasonic wave in order to detect the location of a target to be treated such as calculi situated within the kidney, liver, biliary ducts. A therapeutical energy generator generates a shock wave of sufficient energy for purposes of therapy externally of the physical body and focuses it upon the target. Structure is provided for causing a displacement of the generator and the measuring apparatus around the surface of a patient. Structure is provided to activate the generator.
摘要翻译：治疗装置包括测量装置，其包括产生X射线或超声波的探针，以便检测待处理的靶的位置，例如位于肾，肝，胆管内的结石。治疗能量发生器产生足够能量的冲击波，用于在身体外部治疗的目的，并将其聚焦在目标上。提供了用于使发生器和测量装置围绕患者表面的位移的结构。提供结构来激活发电机。

7. 发明授权

US4982725A Endoscope apparatus 失效
标题翻译：内窥镜装置
公开(公告)号：US4982725A
公开(公告)日：1991-01-08
申请号：US535216
申请日：1990-06-08
申请人： Hiroki Hibino , Yoshikatsu Nagayama , Mutsumi Yoshikawa , Toshiyuki Takara , Masahito Goto , Akira Suzuki , Sakae Takehana , Yoshinao Oaki , Koichi Yoshimitsu , Yoshisada Aoki
发明人： Hiroki Hibino , Yoshikatsu Nagayama , Mutsumi Yoshikawa , Toshiyuki Takara , Masahito Goto , Akira Suzuki , Sakae Takehana , Yoshinao Oaki , Koichi Yoshimitsu , Yoshisada Aoki
IPC分类号： A61B1/005 , A61B1/12
CPC分类号： A61B1/12 , A61B1/00039 , A61B1/00055 , A61B1/0016 , A61B1/0052 , A61B5/6885
摘要： The endoscope apparatus comprises an endoscope having an elongate insertable part having a bendable part and a driving apparatus for bending and driving the bendable part, a first bending controlling apparatus for controlling the driving apparatus and a second bending controlling apparatus for controlling the driving apparatus independently of the first bending controlling apparatus when the first bending controlling apparatus is controllable.
摘要翻译：所述内窥镜装置具有内窥镜，具有具有弯曲部的细长可插入部和用于弯曲和驱动所述弯曲部的驱动装置，用于控制所述驱动装置的第一弯曲控制装置和用于独立于所述驱动装置的所述驱动装置的控制的第二弯曲控制装置当第一弯曲控制装置是可控的时，第一弯曲控制装置。

8. 发明授权

US4853773A Endoscope signal processing apparatus using sequential and synchronous imaging devices 失效
标题翻译：使用顺序和同步成像装置的内窥镜信号处理装置
公开(公告)号：US4853773A
公开(公告)日：1989-08-01
申请号：US150259
申请日：1988-01-29
申请人： Hiroki Hibino , Kenji Kimura , Teruo Eino
发明人： Hiroki Hibino , Kenji Kimura , Teruo Eino
IPC分类号： A61B1/04 , H04N5/225 , H04N7/18 , H04N9/04
CPC分类号： H04N9/045 , H04N5/2251 , H04N5/335 , H04N7/183 , H04N2005/2255
摘要： The endoscope signal processing apparatus is provided with a first signal processing device processing the signal for a field sequential type imaging device and a second signal processing device processing the signal for a synchronous type imaging device. One signal processing device has a circuit partly used in common with the other signal processing device. Both signal processing device have a common video signal output end from which video signals from both signal processing devices are output. This apparatus is further provided with a discriminating device discriminating the imaging system of the endoscope to be connected and an output switching device whereby the video signal transmitted through the video signal processing device corresponding to the imaging system discriminated by this discriminating device is led selectively to the common video signal output.
摘要翻译：内窥镜信号处理装置具有处理场顺序型成像装置的信号的第一信号处理装置和处理同步型成像装置的信号的第二信号处理装置。一个信号处理装置具有与其他信号处理装置共同部分使用的电路。两个信号处理装置具有公共的视频信号输出端，从该信号输出端输出来自两个信号处理装置的视频信号。该装置还具有区分待连接的内窥镜的摄像系统的鉴别装置和输出切换装置，由此通过与由该识别装置识别的成像系统相对应的视频信号处理装置发送的视频信号选择性地被引导到公共视频信号输出。

9. 发明授权

US4816909A Video endoscope system for use with different sizes of solid state devices 失效
标题翻译：视频内窥镜系统适用于不同尺寸的固态设备
公开(公告)号：US4816909A
公开(公告)日：1989-03-28
申请号：US134627
申请日：1987-12-16
申请人： Kenji Kimura , Masao Uehara , Hiroki Hibino , Akinobu Uchikubo , Jun Hasegawa , Masahide Kanno , Shinji Yamashita , Masahiko Sasaki , Katuyoshi Sasagawa
发明人： Kenji Kimura , Masao Uehara , Hiroki Hibino , Akinobu Uchikubo , Jun Hasegawa , Masahide Kanno , Shinji Yamashita , Masahiko Sasaki , Katuyoshi Sasagawa
IPC分类号： H04N5/225 , H04N9/04 , A61B1/04
CPC分类号： A61B1/045 , A61B1/00006 , H04N9/045 , H04N2005/2255
摘要： An endoscope contains or is externally fitted with a color imaging device using a solid state imaging device and a signal processing device processing a signal for the endoscope. The color imaging device and solid state imaging device are provided so that the number of pixels and the kind of spectral characteristic of the color imaging device of the endoscope to be connected may be discriminated to process the signal even for the endoscopes having number of pixels and the spectral characteristic.
摘要翻译：内窥镜包含或外部装有使用固态成像装置的彩色成像装置和处理内窥镜的信号的信号处理装置。提供了彩色成像装置和固态成像装置，使得即使对于具有像素数的内窥镜也可以区分要连接的内窥镜的彩色成像装置的像素数量和光谱特性的种类来处理该信号，光谱特征。

10. 发明授权

US08548598B2 Nerve stimulation apparatus 有权
标题翻译：神经刺激装置
公开(公告)号：US08548598B2
公开(公告)日：2013-10-01
申请号：US13417633
申请日：2012-03-12
申请人： Keiichiro Nakajima , Hiroki Hibino
发明人： Keiichiro Nakajima , Hiroki Hibino
IPC分类号： A61N1/00
CPC分类号： A61N1/36114 , A61N1/36135 , A61N1/36167
摘要： Provided is a nerve stimulation apparatus that is capable of performing effective nerve stimulation depending on a therapeutic purpose without adversely affecting a heart. Further provided is a nerve stimulation apparatus including: a stimulation-pulse output unit that outputs a stimulation pulse; a cardiac-event detector that detects a cardiac event; and a controller that controls the stimulation-signal output unit so as to output, during a cardiac refractory period, the nerve stimulation signal having an intensity that corresponds to the heart rate obtained on the basis of the cardiac event detected by the cardiac-event detector.
摘要翻译：本发明提供一种神经刺激装置，其能够根据治疗目的进行有效的神经刺激，而不会不利地影响心脏。进一步提供一种神经刺激装置，包括：刺激脉冲输出单元，其输出刺激脉冲; 检测心脏事件的心脏事件检测器; 以及控制器，其控制所述刺激信号输出单元，以便在心脏不应期期间输出所述神经刺激信号，所述神经刺激信号具有与基于由所述心脏事件检测器检测到的所述心脏事件获得的心率相对应的强度。

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