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1. 发明授权

US5932452A Process for the production of xylose by hydrolysis of hemicellulose by immobilized enzymes 失效
标题翻译：通过固定化酶水解半纤维素来生产木糖的方法
公开(公告)号：US5932452A
公开(公告)日：1999-08-03
申请号：US289803
申请日：1994-08-12
申请人： Annikka Mustranta , Kaisa Poutanen , Heikki Heikkila , Marja-Leena Sarkki
发明人： Annikka Mustranta , Kaisa Poutanen , Heikki Heikkila , Marja-Leena Sarkki
IPC分类号： C12N11/08 , C12N9/24 , C12N11/02 , C12P19/02 , C12P19/14
CPC分类号： C12Y302/01032 , C12N11/02 , C12N9/248 , C12P19/02 , C12Y302/01008 , C12Y302/01037 , C12Y302/01072
摘要： The invention relates to a process for the hydrolysis of a hemicellulose substrate containing xylo-oligomers with an immobilized enzyme by adjusting the pH of an aqueous solution containing hemicellulose oligosaccharides and optionally ionic components to a value within a weakly acidic range, and contacting the solution with a hemicellulolytic enzyme or mixture of enzymes immobilized on a regenerable weak cation exchange carrier without fixing additives, and recovering xylose from the solution. The invention also concerns an enzyme preparation to be used in the process, comprising a weak cation exchange carrier and a hemicellulolytic enzyme or mixture of enzymes immobilized on said carrier.
摘要翻译： PCT No.PCT / FI90 / 00206 Sec。 371日期：1992年3月27日 102（e）日期1992年3月27日PCT提交1990年9月21日PCT公布。出版物WO91 / 03566 日期1991年3月21日本发明涉及通过将含有半纤维素寡糖和任选的离子组分的水溶液的pH调节至弱酸性范围内的值来水解具有固定化酶的含有低聚木糖的半纤维素底物的方法，并将溶液与固定在可再生的弱阳离子交换载体上的半纤维素分解酶或酶的混合物接触而不固定添加剂，并从溶液中回收木糖。本发明还涉及在该方法中使用的酶制剂，其包含弱阳离子交换载体和半纤维素分解酶或固定在所述载体上的酶的混合物。

2. 发明申请

US20110123692A1 CRYSTALLIZATION OF POLYOL COMPOSITIONS, CRYSTALLINE POLYOL COMPOSITION PRODUCT AND USE THEREOF 有权
标题翻译：多元醇组合物的晶体结构，结晶聚合物组合物的制备及其用途
公开(公告)号：US20110123692A1
公开(公告)日：2011-05-26
申请号：US12914317
申请日：2010-10-28
申请人： Olli-Pekka Eroma , Johanna Nygren , Heikki Heikkila , Per Bo Sorensen , Marja-Leena Sarkki , Ian Fairs , Hakan Gros
发明人： Olli-Pekka Eroma , Johanna Nygren , Heikki Heikkila , Per Bo Sorensen , Marja-Leena Sarkki , Ian Fairs , Hakan Gros
IPC分类号： A23L1/00
CPC分类号： A23G1/40 , A21D2/181 , A23G3/38 , A23G3/42 , A23G4/10 , A23L27/34 , C07C31/18
摘要： The present invention relates to microcrystallized polyol comprising at least two polyols, wherein said polyols are selected from the group consisting of maltitol, xylitol and lactitol and wherein said composition contains at least 35% by weight of each of at least two of said polyols microcrystallized together into a solid microcrystalline product. The present invention also relates to a process for the microcrystallization of polyols into a polyol composition. The microcrystallized polyol composition can be used in confectionery, foodstuffs, oral hygiene products and pharmaceuticals and in dietetic products.
摘要翻译：本发明涉及包含至少两种多元醇的微晶多元醇，其中所述多元醇选自麦芽糖醇，木糖醇和乳糖醇，并且其中所述组合物含有至少35重量％的至少两种所述多元醇微晶化成为固体微晶产品。本发明还涉及将多元醇微晶化为多元醇组合物的方法。微晶多元醇组合物可用于糖果，食品，口腔卫生产品和药物以及饮食产品中。

3. 发明授权

US6146856A Process for the production of isomatulose and other products 失效
标题翻译：异麦芽酮糖等生产工艺
公开(公告)号：US6146856A
公开(公告)日：2000-11-14
申请号：US82555
申请日：1998-05-21
申请人： Heikki Heikkila , Marja-Leena Sarkki , Mirja Lindroos , Paivi Ojala , Vili Ravanko , Matti Tylli
发明人： Heikki Heikkila , Marja-Leena Sarkki , Mirja Lindroos , Paivi Ojala , Vili Ravanko , Matti Tylli
IPC分类号： C07H15/04 , C12N9/90 , C12P19/24 , C13K3/00 , C13K13/00 , C12P19/12
CPC分类号： C07H15/04 , C12N9/90 , C12P19/24 , C13K13/00 , C13K13/007 , C13K3/00
摘要： The present invention relates to a process for the simultaneous production of converted and non-converted sugar and/or non-sugar products. The process is especially adapted to the simultaneous production of isomaltulose and/or trehalulose, and betaine or invert sugar from plant derived juices. Sucrose in said juices are enzymatically converted into isomaltulose and trehalulose and the target products are separately recovered from the resulting solution. The isomaltulose may be further converted into isomalt.
摘要翻译：本发明涉及同时生产转化和未转化的糖和/或非糖产品的方法。该方法特别适用于从植物来源的果汁同时生产异麦芽酮糖和/或海藻糖，以及甜菜碱或转化糖。所述果汁中的蔗糖酶促转化成异麦芽酮糖和海藻糖，并从所得溶液中分别回收目标产物。异麦芽酮糖可进一步转化成异麦芽酮糖醇。

4. 发明授权

US07838055B2 Crystallization of polyol compositions, crystalline polyol composition product and use thereof 有权
标题翻译：多元醇组合物的结晶，结晶多元醇组合物产品及其用途
公开(公告)号：US07838055B2
公开(公告)日：2010-11-23
申请号：US10517692
申请日：2003-07-02
申请人： Olli-Pekka Eroma , Johanna Nygren , Heikki Heikkila , Per Bo Sorensen , Marja-Leena Sarkki , Ian Fairs , Hakan Gros
发明人： Olli-Pekka Eroma , Johanna Nygren , Heikki Heikkila , Per Bo Sorensen , Marja-Leena Sarkki , Ian Fairs , Hakan Gros
IPC分类号： A23C3/037 , A23L1/236 , A23G4/00 , C07H1/06 , C07H1/08
CPC分类号： A23G1/40 , A21D2/181 , A23G3/38 , A23G3/42 , A23G4/10 , A23L27/34 , C07C31/18
摘要： The present invention relates to a microcrystallized polyol comprising at least two polyols, wherein said polyols are selected from the group consisting of maltitol, xylitol and lactitol and wherein said composition contains at least 25% by weight of each of at least two of said polyols microcrystallized together into a solid microcrystalline product. The present invention also relates to a process for the microcrystallization of polyols into a polyol composition. The microcrystallized polyol composition can be used in confectionery, foodstuffs, oral hygiene products and pharmaceuticals and in dietetic products.
摘要翻译：本发明涉及包含至少两种多元醇的微晶多元醇，其中所述多元醇选自麦芽糖醇，木糖醇和乳糖醇，并且其中所述组合物含有至少25重量％的至少两种所述多元醇微晶化一起成为固体微晶产品。本发明还涉及将多元醇微晶化为多元醇组合物的方法。微晶多元醇组合物可用于糖果，食品，口腔卫生产品和药物以及饮食产品中。

5. 发明授权

US07482144B2 Method for the production of xylitol 失效
标题翻译：生产木糖醇的方法
公开(公告)号：US07482144B2
公开(公告)日：2009-01-27
申请号：US10341220
申请日：2003-01-13
申请人： Heikki Ojamo , Merja Penttila , Heikki Heikkila , Jaana Uusitalo , Marja Ilmen , Marja-Leena Sarkki , Maija-Leena Vehkomaki
发明人： Heikki Ojamo , Merja Penttila , Heikki Heikkila , Jaana Uusitalo , Marja Ilmen , Marja-Leena Sarkki , Maija-Leena Vehkomaki
IPC分类号： C12P7/18 , C12N7/16 , C12N1/18
CPC分类号： C12P7/18
摘要： The invention relates to a method for the production of xylitol, the method comprising (a1) providing (i) a microorganism having xylanolytic activity, and (ii) a microorganism capable of converting a pentose sugar to xylitol; or (a2) providing a microorganism having xylanolytic activity and being capable of converting a pentose sugar to xylitol, (b) culturing the microorganism of step (a1) (i) or the microorganism of step (a2) in a medium comprising polymer or oligomer materials containing pentose sugars in conditions sufficient for enabling hydrolysis of said polymers or oligomers by the microorganism; (c) producing xylitol in the microorganism of step (a1) (ii) or in the microorganism of step (a2) by bioconversion of the hydrolysis products obtained in step (b), and (d) recovering said xylitol produced. The invention also relates to a microorganism, which has xylanolytic activity and has been genetically modified (i) to enhance its xylanolytic activity, and (ii) to reduce its xylitol metabolism.
摘要翻译：本发明涉及一种生产木糖醇的方法，所述方法包括（a1）提供（i）具有木聚糖分解活性的微生物和（ii）能够将戊糖转化成木糖醇的微生物; 或（a2）提供具有木聚糖分解活性并能够将戊糖转化为木糖醇的微生物，（b）在包含聚合物或低聚物的培养基中培养步骤（a1）（i）的微生物或步骤（a2）的微生物）在足以使微生物水解所述聚合物或低聚物的条件下含有戊糖的材料; （c）通过步骤（b）中获得的水解产物的生物转化和（d）回收所生产的木糖醇，在步骤（a1）（ⅱ）的微生物中或在步骤（a2）的微生物中生产木糖醇。本发明还涉及一种具有木聚糖分解活性且经遗传修饰的微生物（i）增强其木聚糖分解活性，和（ii）降低其木糖醇代谢。

6. 发明授权

US5939294A Immobilization of microogranisms on weakly basic anion exchange substance for producing isomaltulose 失效
标题翻译：将微生物固定在用于转化蔗糖的阴离子交换物质上
公开(公告)号：US5939294A
公开(公告)日：1999-08-17
申请号：US857808
申请日：1997-05-16
申请人： Marja-Leena Sarkki , Heikki Heikkila , Tapio Viljava
发明人： Marja-Leena Sarkki , Heikki Heikkila , Tapio Viljava
IPC分类号： C12N9/90 , C12N11/12 , C12P19/24 , C12P19/12 , C12N11/02 , C12N11/08
CPC分类号： C12R1/01 , C12N11/12 , C12N9/90 , C12P19/24
摘要： Isomaltulose-forming microorganisms are immobilized on a carrier that is a weakly basic anion exchange substance in the form of a substantially non-compressible porous particulate solid material, and are used for isomerization of sucrose to isomaltulose. A preferred carrier contains microfibers or microparticles of diethylaminoethyl cellulose adherently bound by agglomeration with polystyrene. The isomerization may be a continuous conversion in one or more columns packed with the carrier. Isomaltulose may be hydrogenated to form isomalt for use in sweetening. Microorganisms can be immobilized on the carrier by feeding microorganisms to a column containing the carrier. After microorganism immobilization, the carrier may be treated with a crosslinking and/or flocculating compound. Regeneration of the carrier is carried out by removing microorganisms, washing and reloading with fresh microorganisms.
摘要翻译：异麦芽酮糖形成微生物固定在作为基本上不可压缩的多孔颗粒固体材料形式的弱碱性阴离子交换物质的载体上，并用于将蔗糖异构化成异麦芽酮糖。优选的载体包含通过与聚苯乙烯附聚粘附结合的二乙基氨基乙基纤维素的微纤维或微粒。异构化可以是在一个或多个填充有载体的柱中的连续转化。异麦芽酮糖可以被氢化以形成用于增甜的异麦芽酮糖醇。微生物可以通过将微生物送入含有载体的柱中而固定在载体上。微生物固定后，载体可以用交联和/或絮凝化合物处理。通过除去微生物，用新鲜的微生物清洗和重新装载来进行载体的再生。

7. 发明申请

US20060246563A1 Process for the simultaneous production of xylitol and ethanol 失效
公开(公告)号：US20060246563A1
公开(公告)日：2006-11-02
申请号：US11479654
申请日：2006-06-30
申请人： Olli-Pekka Eroma , Heikki Heikkila , Heikki Ojamo , Paivi Sarmala , Goran Hyoky , Leena Rahkila , Marja-Leena Sarkki , Tapio Viljava
发明人： Olli-Pekka Eroma , Heikki Heikkila , Heikki Ojamo , Paivi Sarmala , Goran Hyoky , Leena Rahkila , Marja-Leena Sarkki , Tapio Viljava
IPC分类号： C12P7/18 , C12P7/06
CPC分类号： C12P7/10 , B01D61/025 , C12P7/12 , C12P7/18 , Y02E50/16 , Y02E50/17 , Y10S435/911 , Y10S435/921 , Y10S435/924
摘要： Effective processes are provided for the production of xylitol and ethanol and other products from solutions derived from lignocellulose-containing material in biomass. The solutions can be hydrolyzed or partially hydrolyzed before being fermented with microbes. The fermented solution can be distilled and can be subsequently separated, such as, by chromatographic separation, membrane separation, etc. The recovered xylitol solution can be crystallized to provide pure xylitol crystals.

8. 发明申请

US20060025584A1 Crystallization of polyol compositions, crystalline polyol composition product and use thereof 有权
标题翻译：多元醇组合物的结晶，结晶多元醇组合物产品及其用途
公开(公告)号：US20060025584A1
公开(公告)日：2006-02-02
申请号：US10517692
申请日：2003-07-02
申请人： Olli-Pekka Eroma , Johanna Nygren , Heikki Heikkila , Per Bo Sorensen , Marja-Leena Sarkki , Ian Fairs , Hakan Gros
发明人： Olli-Pekka Eroma , Johanna Nygren , Heikki Heikkila , Per Bo Sorensen , Marja-Leena Sarkki , Ian Fairs , Hakan Gros
IPC分类号： C07H3/04 , C07C31/18
CPC分类号： A23G1/40 , A21D2/181 , A23G3/38 , A23G3/42 , A23G4/10 , A23L27/34 , C07C31/18
摘要： The present invention relates to a microcrystallized polyol comprising at least two polyols, wherein said polyols are selected from the group consisting of maltitol, xylitol and lactitol and wherein said composition contains at least 25% by weight of each of at least two of said polyols microcrystallized together into a solid microcrystalline product. The present invention also relates to a process for the microcrystallization of polyols into a polyol composition. The microcrystallized polyol composition can be used in confectionery, foodstuffs, oral hygiene products and pharmaceuticals and in dietetic products.
摘要翻译：本发明涉及包含至少两种多元醇的微晶多元醇，其中所述多元醇选自麦芽糖醇，木糖醇和乳糖醇，并且其中所述组合物含有至少25重量％的至少两种所述多元醇微晶化一起成为固体微晶产品。本发明还涉及将多元醇微晶化为多元醇组合物的方法。微晶多元醇组合物可用于糖果，食品，口腔卫生产品和药物以及饮食产品中。

9. 发明授权

US06512110B1 Process for the production of xylose from a paper-grade hardwood pulp 失效
标题翻译：用于从纸级硬木纸浆生产木糖的方法
公开(公告)号：US06512110B1
公开(公告)日：2003-01-28
申请号：US09456902
申请日：1999-12-08
申请人： Heikki Heikkila , Marja-Leena Sarkki , Vili Ravanko , Mirja Lindroos
发明人： Heikki Heikkila , Marja-Leena Sarkki , Vili Ravanko , Mirja Lindroos
IPC分类号： C07H106
CPC分类号： C12P19/14 , C12N9/248 , C13B20/02 , C13K13/002 , D21C5/005 , D21C9/00 , D21C9/002
摘要： The invention relates to a process for the production of xylose from a paper-grade hardwood pulp comprising the steps of extracting xylan contained in said pulp into a liquid phase, subjecting the xylan contained in the obtained liquid phase to conditions sufficient to hydrolyze xylan to xylose, and recovering the xylose, wherein the extracting step includes at least one treatment of an aqueous suspension of said pulp or an alkali-soluble material thereof with a xylanase enzyme.
摘要翻译：本发明涉及从纸级硬木浆生产木糖的方法，包括以下步骤：将所述纸浆中含有的木聚糖提取到液相中，使得到的液相中含有的木聚糖使足够水解木聚糖至木糖的条件并回收木糖，其中提取步骤包括至少一种处理所述纸浆的水性悬浮液或其碱溶性物质与木聚糖酶。

10. 发明授权

US08192775B2 Crystallization of polyol compositions, crystalline polyol composition product and use thereof 有权
标题翻译：多元醇组合物的结晶，结晶多元醇组合物产品及其用途
公开(公告)号：US08192775B2
公开(公告)日：2012-06-05
申请号：US12914317
申请日：2010-10-28
申请人： Olli-Pekka Eroma , Johanna Nygren , Heikki Heikkila , Per Bo Sorensen , Marja-Leena Sarkki , Ian Fairs , Hakan Gros
发明人： Olli-Pekka Eroma , Johanna Nygren , Heikki Heikkila , Per Bo Sorensen , Marja-Leena Sarkki , Ian Fairs , Hakan Gros
IPC分类号： A23C3/037 , A23L1/236 , A23G4/00 , C07H1/06 , C07H1/08
CPC分类号： A23G1/40 , A21D2/181 , A23G3/38 , A23G3/42 , A23G4/10 , A23L27/34 , C07C31/18
摘要： The present invention relates to microcrystallized polyol comprising at least two polyols, wherein said polyols are selected from the group consisting of maltitol, xylitol and lactitol and wherein said composition contains at least 35% by weight of each of at least two of said polyols microcrystallized together into a solid microcrystalline product. The present invention also relates to a process for the microcrystallization of polyols into a polyol composition. The microcrystallized polyol composition can be used in confectionery, foodstuffs, oral hygiene products and pharmaceuticals and in dietetic products.
摘要翻译：本发明涉及包含至少两种多元醇的微晶多元醇，其中所述多元醇选自麦芽糖醇，木糖醇和乳糖醇，并且其中所述组合物含有至少35重量％的至少两种所述多元醇微晶化成为固体微晶产品。本发明还涉及将多元醇微晶化为多元醇组合物的方法。微晶多元醇组合物可用于糖果，食品，口腔卫生产品和药物以及饮食产品中。

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