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1. 发明授权

US07909038B2 Tongue stabilization device and methods of using the same 有权
标题翻译：舌稳定装置及其使用方法
公开(公告)号：US07909038B2
公开(公告)日：2011-03-22
申请号：US11847271
申请日：2007-08-29
申请人： Anant V. Hegde , Kasey Kai-Chi Li , Nikhil D. Bhat , Christopher Bagley , Casidy Hallsten , George Y. Choi , Doyeon Kim
发明人： Anant V. Hegde , Kasey Kai-Chi Li , Nikhil D. Bhat , Christopher Bagley , Casidy Hallsten , George Y. Choi , Doyeon Kim
IPC分类号： A61F5/56 , F16F1/00 , F16F9/00 , A61J7/00 , A61M31/00 , A61M37/00 , A61M5/20
CPC分类号： A61F5/56 , A61B2017/248 , A61F5/566 , A61F2210/0038 , Y10S602/902
摘要： An airway implant device for maintaining and/or creating an opening in air passageways is disclosed. Methods of using the device are also disclosed. The implant is an implant for stabilizing the tongue, the implant having an anchoring portion for securing a first end of the implant with the mandibula; a control portion connected with the anchoring portion, configured for selectively activating the implant; a flexible portion connected at its proximal end with the control portion, where the flexible portion has three-dimensional flexibility in a first state and where the flexible portion has a lesser three-dimensional flexibility in a second state, and where the flexible portion is selectively switchable between the first and second state by the control portion; an anchoring portion for connecting the implant with the base of the tongue connected with the flexible portion, and a latch mechanism coupled with the control portion and configured to maintain the flexible portion in either of the first and second states. Methods of treating airway disorders such as sleep apnea and snoring with the airway implant device are disclosed herein.
摘要翻译：公开了一种用于在空气通道中保持和/或形成开口的气道植入装置。还公开了使用该装置的方法。植入物是用于稳定舌头的植入物，所述植入物具有用于固定植入物的第一端与下颌骨的锚定部分; 与所述锚定部分连接的控制部分，被配置为选择性地启动所述植入物; 其柔性部分在其近端连接有控制部分，其中柔性部分在第一状态下具有三维柔性，并且柔性部分在第二状态下具有较小的三维柔性，并且其中柔性部分是选择性的通过控制部在第一状态和第二状态之间切换; 用于将植入物与与柔性部分连接的舌片的基部连接的锚定部分，以及与控制部分联接并被配置为将柔性部分保持在第一状态和第二状态中的任一状态的闩锁机构。本文公开了用气道植入装置处理呼吸道疾病如睡眠呼吸暂停和打鼾的方法。

2. 发明申请

US20090173351A1 CONTROL SYSTEM FOR A TONGUE STABILIZATION DEVICE 审中-公开
标题翻译：用于稳定稳定装置的控制系统
公开(公告)号：US20090173351A1
公开(公告)日：2009-07-09
申请号：US12250398
申请日：2008-10-13
申请人： Koray Sahin , Anant V. Hegde , Kasey Kai-Chi Li , Nikhil D. Bhat , Christopher Bagley , Casidy Domingo , John M. Farbarik , George Y. Choi , Doyeon Kim
发明人： Koray Sahin , Anant V. Hegde , Kasey Kai-Chi Li , Nikhil D. Bhat , Christopher Bagley , Casidy Domingo , John M. Farbarik , George Y. Choi , Doyeon Kim
IPC分类号： A61F5/56 , G06F19/00
CPC分类号： A61F2/02 , A61B2017/248 , A61F5/56 , A61F5/566 , A61F2210/0038
摘要： A tongue implant control system and methods for stabilizing the tongue are disclosed. The tongue implant control system includes an implant device and a non-implanted control device in wireless communication. The control device provides an inductive power transfer for operating the implant device. The control device also sends commands for changing a state of the implant device. The implant device includes a flexible portion for attachment to the tongue and to one or more actuators. The one or more actuators may include shape memory material. The implant device detects a command from the control device and powers an actuator based on the command. Optionally, the implant device communicates its operating state to the control device and the control device displays information about the implant device at a user interface.
摘要翻译：公开了一种舌植入物控制系统和用于稳定舌头的方法。舌植入物控制系统包括无线通信中的植入装置和非植入式控制装置。控制装置提供用于操作植入装置的感应功率传递。控制装置还发送用于改变植入装置的状态的命令。植入装置包括用于附接到舌头和一个或多个致动器的柔性部分。一个或多个致动器可以包括形状记忆材料。植入装置根据该命令检测来自控制装置的命令并对致动器供电。可选地，植入装置将其操作状态传达到控制装置，并且控制装置在用户界面处显示关于植入装置的信息。

3. 发明授权

US07909037B2 Tethered airway implants and methods of using the same 有权
标题翻译：束缚气道植入物及其使用方法
公开(公告)号：US07909037B2
公开(公告)日：2011-03-22
申请号：US11737107
申请日：2007-04-18
申请人： Anant V. Hegde , Kasey Kai-Chi Li , Nikhil D. Bhat , Doyeon Kim , George Y. Choi
发明人： Anant V. Hegde , Kasey Kai-Chi Li , Nikhil D. Bhat , Doyeon Kim , George Y. Choi
IPC分类号： A61F5/56 , A61F13/00 , A61F5/04 , A61F2/30 , A61F2/00 , A61B19/00 , A61B17/56 , A61B17/58 , A61B17/70
CPC分类号： A61F5/56 , A61B2017/248 , A61F5/566 , G02B26/0841 , H02N1/008 , Y10S602/902
摘要： An airway implant device for maintaining and/or creating an opening in air passageways is disclosed. Methods of using the device are also disclosed. The airway implant device includes a deformable element to control the opening of an air passageway and a tether. Preferably the deformable element is an electroactive polymer element. Energizing of the electroactive polymer element provides support for the walls of an air passageway, when the walls collapse, and thus, completely or partially opens the air passageway. Also disclosed is an implant for stabilizing the tongue, the implant having an anchoring portion for securing a first end of the implant with the mandibula; a control portion connected with the anchoring portion, configured for selectively activating the implant; a flexible portion connected at its proximal end with the control portion, where the flexible portion has three-dimensional flexibility in a first state and where the flexible portion has a lesser three-dimensional flexibility in a second state, and where the flexible portion is selectively switchable between the first and second state by the control portion; and an anchoring portion for connecting the implant with the base of the tongue connected with the distal end of the flexible portion. Methods of treating airway disorders such as sleep apnea and snoring with the airway implant device are disclosed herein.
摘要翻译：公开了一种用于在空气通道中保持和/或形成开口的气道植入装置。还公开了使用该装置的方法。气道植入装置包括可变形元件以控制空气通道和系绳的开口。优选地，可变形元件是电活性聚合物元件。电活性聚合物元件的通电为空气通道的壁提供支撑，当壁崩溃时，从而完全或部分地打开空气通道。还公开了一种用于稳定舌头的植入物，植入物具有用于固定植入物的第一端与下颌骨的锚固部分; 与所述锚定部分连接的控制部分，被配置为选择性地启动所述植入物; 其柔性部分在其近端连接有控制部分，其中柔性部分在第一状态下具有三维柔性，并且柔性部分在第二状态下具有较小的三维柔性，并且其中柔性部分是选择性的通过控制部在第一状态和第二状态之间切换; 以及用于将植入物与与柔性部分的远端连接的舌头的基部连接的锚固部分。本文公开了用气道植入装置处理呼吸道疾病如睡眠呼吸暂停和打鼾的方法。

4. 发明申请

US20070246052A1 Tethered Airway Implants and Methods of Using the Same 有权
标题翻译：绑扎气道植入物及其使用方法
公开(公告)号：US20070246052A1
公开(公告)日：2007-10-25
申请号：US11737107
申请日：2007-04-18
申请人： Anant V. Hegde , Kasey Kai-Chi Li , Nikhil D. Bhat , Doyeon Kim , George Y. Choi
发明人： Anant V. Hegde , Kasey Kai-Chi Li , Nikhil D. Bhat , Doyeon Kim , George Y. Choi
IPC分类号： A61F5/56
CPC分类号： A61F5/56 , A61B2017/248 , A61F5/566 , G02B26/0841 , H02N1/008 , Y10S602/902
摘要： An airway implant device for maintaining and/or creating an opening in air passageways is disclosed. Methods of using the device are also disclosed. The airway implant device includes a deformable element to control the opening of an air passageway and a tether. Preferably the deformable element is an electroactive polymer element. Energizing of the electroactive polymer element provides support for the walls of an air passageway, when the walls collapse, and thus, completely or partially opens the air passageway. Also disclosed is an implant for stabilizing the tongue, the implant having an anchoring portion for securing a first end of the implant with the mandibula; a control portion connected with the anchoring portion, configured for selectively activating the implant; a flexible portion connected at its proximal end with the control portion, where the flexible portion has three-dimensional flexibility in a first state and where the flexible portion has a lesser three-dimensional flexibility in a second state, and where the flexible portion is selectively switchable between the first and second state by the control portion; and an anchoring portion for connecting the implant with the base of the tongue connected with the distal end of the flexible portion. Methods of treating airway disorders such as sleep apnea and snoring with the airway implant device are disclosed herein.
摘要翻译：公开了一种用于在空气通道中保持和/或形成开口的气道植入装置。还公开了使用该装置的方法。气道植入装置包括可变形元件以控制空气通道和系绳的开口。优选地，可变形元件是电活性聚合物元件。电活性聚合物元件的通电为空气通道的壁提供支撑，当壁崩溃时，从而完全或部分地打开空气通道。还公开了一种用于稳定舌头的植入物，植入物具有用于固定植入物的第一端与下颌骨的锚固部分; 与所述锚定部分连接的控制部分，被配置为选择性地启动所述植入物; 其柔性部分在其近端连接有控制部分，其中柔性部分在第一状态下具有三维柔性，并且柔性部分在第二状态下具有较小的三维柔性，并且其中柔性部分是选择性的通过控制部在第一状态和第二状态之间切换; 以及用于将植入物与与柔性部分的远端连接的舌头的基部连接的锚固部分。本文公开了用气道植入装置处理呼吸道疾病如睡眠呼吸暂停和打鼾的方法。

5. 发明授权

US08555891B2 Implant system for controlling airway passage 有权
标题翻译：用于控制气道通道的植入系统
公开(公告)号：US08555891B2
公开(公告)日：2013-10-15
申请号：US12785391
申请日：2010-05-21
申请人： Adam Sharkawy , Koray Sahin , Adrian McVicker , Jon F. Moss , Casidy Domingo , Nikhil D. Bhat , Christopher Bagley , Anant V. Hegde , John M. Farbarik , George Y. Choi , Kasey Kai-Chi Li
发明人： Adam Sharkawy , Koray Sahin , Adrian McVicker , Jon F. Moss , Casidy Domingo , Nikhil D. Bhat , Christopher Bagley , Anant V. Hegde , John M. Farbarik , George Y. Choi , Kasey Kai-Chi Li
IPC分类号： A61F5/56 , A61B1/32
CPC分类号： A61F5/566 , A61F5/56
摘要： Techniques for operating a subcutaneous implant device are disclosed. The implant device can be formed of a non-magnetic material that is compatible with diagnostics such as magnetic resonance imaging (MRI) and can include a rotor element that rotates under the influence of an external magnetic field. The implant device includes a tension relief mechanism for relieving excessive force applied between the implant device and a portion of a patient's tongue. A non-implanted device can include a stator and drive circuitry for generating the external magnetic field. The non-implanted device can receive a user command and can vary the external magnetic field based on the command. When activated by the magnetic field, the implant device can change its operating state to interact with the patient's body.
摘要翻译：公开了用于操作皮下植入装置的技术。植入装置可以由与诸如磁共振成像（MRI）的诊断相兼容的非磁性材料形成，并且可以包括在外部磁场的影响下旋转的转子元件。植入装置包括用于减轻施加在植入装置与患者舌头的一部分之间的过大力的张力释放机构。非植入装置可以包括用于产生外部磁场的定子和驱动电路。非植入装置可以接收用户命令并且可以基于命令改变外部磁场。当由磁场激活时，植入装置可以改变其操作状态以与患者的身体相互作用。

6. 发明申请

US20100319710A1 IMPLANT SYSTEM FOR CONTROLLING AIRWAY PASSAGE 有权
标题翻译：用于控制空中通行的植入系统
公开(公告)号：US20100319710A1
公开(公告)日：2010-12-23
申请号：US12785391
申请日：2010-05-21
申请人： Adam Sharkawy , Koray Sahin , Adrian McVicker , Jon F. Moss , Casidy Domingo , Nikhil D. Bhat , Christopher Bagley , Anant V. Hegde , John M. Farbarik , George Y. Choi , Kasey Kai-Chi Li
发明人： Adam Sharkawy , Koray Sahin , Adrian McVicker , Jon F. Moss , Casidy Domingo , Nikhil D. Bhat , Christopher Bagley , Anant V. Hegde , John M. Farbarik , George Y. Choi , Kasey Kai-Chi Li
IPC分类号： A61F5/56
CPC分类号： A61F5/566 , A61F5/56
摘要： Techniques for operating a subcutaneous implant device are disclosed. The implant device can be formed of a non-magnetic material that is compatible with diagnostics such as magnetic resonance imaging (MRI) and can include a rotor element that rotates under the influence of an external magnetic field. The implant device includes a tension relief mechanism for relieving excessive force applied between the implant device and a portion of a patient's tongue. A non-implanted device can include a stator and drive circuitry for generating the external magnetic field. The non-implanted device can receive a user command and can vary the external magnetic field based on the command. When activated by the magnetic field, the implant device can change its operating state to interact with the patient's body.
摘要翻译：公开了用于操作皮下植入装置的技术。植入装置可以由与诸如磁共振成像（MRI）的诊断相兼容的非磁性材料形成，并且可以包括在外部磁场的影响下旋转的转子元件。植入装置包括用于减轻施加在植入装置与患者舌头的一部分之间的过大力的张力释放机构。非植入装置可以包括用于产生外部磁场的定子和驱动电路。非植入装置可以接收用户命令并且可以基于命令改变外部磁场。当由磁场激活时，植入装置可以改变其操作状态以与患者的身体相互作用。

7. 发明申请

US20100049227A1 Delivery Tools for Sleep Disorders Treatment Implant and Methods of Implantation 失效
标题翻译：睡眠障碍治疗植入物和植入方法的交付工具
公开(公告)号：US20100049227A1
公开(公告)日：2010-02-25
申请号：US12168820
申请日：2008-07-07
申请人： Anant V. Hegde , Kasey Kai-Chi Li , Phil Houle , Casidy Hallsten , Chris D. Owen
发明人： Anant V. Hegde , Kasey Kai-Chi Li , Phil Houle , Casidy Hallsten , Chris D. Owen
IPC分类号： A61B17/3209 , A61F5/56 , A61B17/00
CPC分类号： A61F2/00 , A61B17/320016 , A61B17/3209 , A61B2017/248 , A61F5/56
摘要： Methods and tools are disclosed for inserting an implant device that treats snoring and apnea of a patient by altering the position of a soft palate. Methods and tools can make an incision in patient's soft and hard palate to create a cavity that can house the implant. The tools can have visually observable markings that can be aligned with the incision, thus controlling the depth of the cavity. A needle having an incision edge can be used to make an incision in patient's soft palate. The needle can be bent into a suitable longitudinal shape to allow easier access and visualization of the process. A blade that makes the cavity in the tissue can be housed inside a channel in the needle. The tools may have stoppers to prevent excessive extension and retraction of the blade thus preventing an excessive cavity depth. Some tools may also house the implant device, which may be implanted after the cavity is formed.
摘要翻译：公开了用于插入通过改变软腭的位置来治疗患者的打鼾和呼吸暂停的植入装置的方法和工具。方法和工具可以在病人的柔软和硬腭中形成切口，以创建可容纳植入物的腔体。工具可以具有可与切口对准的视觉上可观察到的标记，从而控制腔的深度。具有切口边缘的针可用于在患者的软腭中进行切口。针可以弯曲成适当的纵向形状，以允许更容易地进入和可视化过程。使得组织中的空腔可以容纳在针的通道内的刀片。工具可以具有止动件以防止叶片的过度的伸展和缩回，从而防止过大的腔深度。一些工具还可以容纳植入装置，其可以在腔形成之后植入。

8. 发明授权

US07980248B2 Delivery tools for sleep disorders treatment implant and methods of implantation 失效
标题翻译：用于睡眠障碍治疗植入物和植入方法的递送工具
公开(公告)号：US07980248B2
公开(公告)日：2011-07-19
申请号：US12168820
申请日：2008-07-07
申请人： Anant V. Hegde , Kasey Kai-Chi Li , Phil Houle , Casidy Hallsten , Chris D. Owen
发明人： Anant V. Hegde , Kasey Kai-Chi Li , Phil Houle , Casidy Hallsten , Chris D. Owen
IPC分类号： A61F5/56
CPC分类号： A61F2/00 , A61B17/320016 , A61B17/3209 , A61B2017/248 , A61F5/56
摘要： Methods and tools are disclosed for inserting an implant device that treats snoring and apnea of a patient by altering the position of a soft palate. Methods and tools can make an incision in patient's soft and hard palate to create a cavity that can house the implant. The tools can have visually observable markings that can be aligned with the incision, thus controlling the depth of the cavity. A needle having an incision edge can be used to make an incision in patient's soft palate. The needle can be bent into a suitable longitudinal shape to allow easier access and visualization of the process. A blade that makes the cavity in the tissue can be housed inside a channel in the needle. The tools may have stoppers to prevent excessive extension and retraction of the blade thus preventing an excessive cavity depth. Some tools may also house the implant device, which may be implanted after the cavity is formed.
摘要翻译：公开了用于插入通过改变软腭的位置来治疗患者的打鼾和呼吸暂停的植入装置的方法和工具。方法和工具可以在病人的柔软和硬腭中形成切口，以创建可容纳植入物的腔体。工具可以具有可与切口对准的视觉上可观察到的标记，从而控制腔的深度。具有切口边缘的针可用于在患者的软腭中进行切口。针可以弯曲成适当的纵向形状，以允许更容易地进入和可视化过程。使得组织中的空腔可以容纳在针的通道内的刀片。工具可以具有止动件以防止叶片的过度的伸展和缩回，从而防止过大的腔深度。一些工具还可以容纳植入装置，其可以在腔形成之后植入。

9. 发明申请

US20110240037A1 Delivery Tools for Sleep Disorders Treatment Implant and Methods of Implantation 审中-公开
标题翻译：睡眠障碍治疗植入物和植入方法的交付工具
公开(公告)号：US20110240037A1
公开(公告)日：2011-10-06
申请号：US13160469
申请日：2011-06-14
申请人： Anant V. Hegde , Kasey Kai-Chi Li , Phil Houle , Casidy Hallsten , Chris D. Owen
发明人： Anant V. Hegde , Kasey Kai-Chi Li , Phil Houle , Casidy Hallsten , Chris D. Owen
IPC分类号： A61F5/56
CPC分类号： A61F2/00 , A61B17/320016 , A61B17/3209 , A61B2017/248 , A61F5/56
摘要： Methods and tools are disclosed for inserting an implant device that treats snoring and apnea of a patient by altering the position of a soft palate. Methods and tools can make an incision in patient's soft and hard palate to create a cavity that can house the implant. The tools can have visually observable markings that can be aligned with the incision, thus controlling the depth of the cavity. A needle having an incision edge can be used to make an incision in patient's soft palate. The needle can be bent into a suitable longitudinal shape to allow easier access and visualization of the process. A blade that makes the cavity in the tissue can be housed inside a channel in the needle. The tools may have stoppers to prevent excessive extension and retraction of the blade thus preventing an excessive cavity depth. Some tools may also house the implant device, which may be implanted after the cavity is formed.
摘要翻译：公开了用于插入通过改变软腭的位置来治疗患者的打鼾和呼吸暂停的植入装置的方法和工具。方法和工具可以在病人的柔软和硬腭中形成切口，以创建可容纳植入物的腔体。工具可以具有可与切口对准的视觉上可观察到的标记，从而控制腔的深度。具有切口边缘的针可用于在患者的软腭中进行切口。针可以弯曲成适当的纵向形状，以允许更容易地进入和可视化过程。使得组织中的空腔可以容纳在针的通道内的刀片。工具可以具有止动件以防止叶片的过度的伸展和缩回，从而防止过大的腔深度。一些工具还可以容纳植入装置，其可以在腔形成之后植入。

10. 发明授权

US08578937B2 Smart mandibular repositioning system 有权
标题翻译：智能下颌骨重新定位系统
公开(公告)号：US08578937B2
公开(公告)日：2013-11-12
申请号：US12235531
申请日：2008-09-22
申请人： Nikhil D. Bhat , Anant V. Hegde , Charisse M. Yung , George Y. Choi
发明人： Nikhil D. Bhat , Anant V. Hegde , Charisse M. Yung , George Y. Choi
IPC分类号： A61F5/56 , A61F5/37
CPC分类号： A61B5/4818 , A61B5/0031 , A61B5/076 , A61B5/1076 , A61B5/682 , A61F2/02 , A61F5/566
摘要： Systems and methods for detecting an obstructive sleep apnea event are disclosed herein. The systems and methods may use an electrical output generating ionic polymer metal composite sensor attached to a region in an airway passage in an oral cavity. The electrical output may be wirelessly transmitted as a signal for indication of an obstructive sleep apnea event. The signal may be further processed by a smart mandibular repositioning system for treatment of the obstructive sleep apnea event.
摘要翻译：本文公开了用于检测阻塞性睡眠呼吸暂停事件的系统和方法。系统和方法可以使用附着在口腔中的气道通道中的区域的电输出产生离子聚合物金属复合传感器。电输出可以作为用于指示阻塞性睡眠呼吸暂停事件的信号被无线发送。该信号可以由用于治疗阻塞性睡眠呼吸暂停事件的智能下颌骨重新定位系统进一步处理。

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