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1. 发明授权

US09662209B2 Contractible annuloplasty structures 有权
公开(公告)号：US09662209B2
公开(公告)日：2017-05-30
申请号：US14128756
申请日：2012-06-21
申请人： Amir Gross , Tal Sheps , Tal Hammer , Tal Reich , Ehud Iflah
发明人： Amir Gross , Tal Sheps , Tal Hammer , Tal Reich , Ehud Iflah
IPC分类号： A61F2/24 , A61B17/072 , A61B17/068 , A61B17/00 , A61B17/064
CPC分类号： A61F2/2445 , A61B17/068 , A61B17/072 , A61B2017/00243 , A61B2017/003 , A61B2017/0649 , A61F2/2448 , A61F2/2466 , A61F2250/0004
摘要： A method is provided, including positioning an annuloplasty structure along an annulus of an atrioventricular valve of a subject, the annuloplasty structure including a sleeve having a lumen. The annuloplasty structure is fastened to the annulus. Thereafter, an elongate member is advanced into the lumen, such that an elongate contraction-restricting element of the elongate member occupies a longitudinal contraction-restricted portion of the sleeve. Thereafter, a contractible portion of the sleeve is contracted, while the contraction-restricting element restricts contraction of the contraction-restricted portion of the sleeve.

2. 发明授权

US08926697B2 Closed band for percutaneous annuloplasty 有权
标题翻译：用于经皮瓣环成形术的闭合带
公开(公告)号：US08926697B2
公开(公告)日：2015-01-06
申请号：US13167492
申请日：2011-06-23
申请人： Amir Gross , Tal Sheps , Tal Hammer , Tal Reich
发明人： Amir Gross , Tal Sheps , Tal Hammer , Tal Reich
IPC分类号： A61F2/24
CPC分类号： A61F2/2445 , A61F2/2466
摘要： An implantable structure includes a flexible sleeve, having first and second sleeve ends, and a contracting assembly, which is configured to longitudinally contract the sleeve, and includes a contracting mechanism, which is disposed longitudinally at a first site of the sleeve, and a longitudinal contracting member, having (a) a first member end, (b) a second member end, which is coupled to the sleeve longitudinally at a second site longitudinally between the first site and the second sleeve end, exclusive, and (c) a first member end portion, which is coupled to the contracting mechanism. The sleeve is arranged in a closed loop, such that first and second portions of the sleeve together define a longitudinally overlapping portion of the sleeve. The implantable structure is configured such that the contracting assembly longitudinally applies a longitudinal contracting force only between the first and the second sites, and not along the overlapping portion.
摘要翻译：可植入结构包括具有第一和第二套筒端部的柔性套筒和构造成纵向收缩套筒的收缩组件，并且包括纵向设置在套筒的第一部位处的收缩机构，纵向具有（a）第一构件端部，（b）第二构件端部，其在第一位置和第二套筒端部之间纵向地在第二位置处纵向联接到套筒，并且（c）第一构件端部构件端部，其连接到收缩机构。套筒被布置成闭合的环，使得套筒的第一和第二部分一起限定套筒的纵向重叠部分。可植入结构构造成使得收缩组件仅在第一和第二部位之间纵向施加纵向收缩力，而不是沿着重叠部分。

3. 发明申请

US20140142695A1 CONTRACTIBLE ANNULOPLASTY STRUCTURES 有权
标题翻译：可逆性鼻咽结构
公开(公告)号：US20140142695A1
公开(公告)日：2014-05-22
申请号：US14128756
申请日：2012-06-21
申请人： Amir Gross , Tal Sheps , Tal Hammer , Tal Reich , Ehud Iflah , Uriel Aba Pomerantz , Oz Cabiri , Yaron Herman
发明人： Amir Gross , Tal Sheps , Tal Hammer , Tal Reich , Ehud Iflah , Uriel Aba Pomerantz , Oz Cabiri , Yaron Herman
IPC分类号： A61F2/24
CPC分类号： A61F2/2445 , A61B17/068 , A61B17/072 , A61B2017/00243 , A61B2017/003 , A61B2017/0649 , A61F2/2448 , A61F2/2466 , A61F2250/0004
摘要： Apparatus is provided including an implantable structure (22), including a flexible sleeve (26), having first and second sleeve ends (49, 51), a contracting assembly (40), which is configured to longitudinally contract the sleeve (26). The contracting assembly (40) includes a contracting mechanism (28), which is at a first site of the sleeve (26); and a longitudinal contracting member (30), having (a) a first member end, (b) a second member end (53), coupled to the sleeve (26) at a second site longitudinally between the first site and the second sleeve end (49 or 51), exclusive. A force-distributing element (540) is couplable to the sleeve (26) in a vicinity of the second sleeve end (49 or 51), element (540) is configured to distribute a contraction force by the contracting member (30) between the second member end (53) and the second sleeve end (49 or 51). Other applications are also described.
摘要翻译：提供了包括可植入结构（22）的装置，其包括具有第一和第二套筒端部（49,51）的柔性套筒（26），收缩组件（40），其构造成纵向收缩套筒（26）。收缩组件（40）包括在套筒（26）的第一位置处的收缩机构（28）; 和纵向收缩构件（30），其具有（a）第一构件端部，（b）第二构件端部（53），其在第一位置和第二套筒端部之间的第二位置处连接到套筒（26）（49或51），独家。力分配元件（540）可在第二套筒端部（49或51）附近与套筒（26）连接，元件（540）构造成将收缩构件（30）的收缩力分配在第二构件端部（53）和第二套筒端部（49或51）。还描述了其它应用。

4. 发明授权

US08523881B2 Multiple anchor delivery tool 有权
标题翻译：多锚定传送工具
公开(公告)号：US08523881B2
公开(公告)日：2013-09-03
申请号：US12843412
申请日：2010-07-26
申请人： Oz Cabiri , Amir Gross , Tal Hammer , Tal Reich , Ehud Iflah
发明人： Oz Cabiri , Amir Gross , Tal Hammer , Tal Reich , Ehud Iflah
IPC分类号： A61B17/10
CPC分类号： A61B17/064 , A61B17/068 , A61B2017/0649 , A61F2/2445
摘要： An anchor deployment tool includes a flexible outer tube, within which is positioned a flexible inner shaft, and a rotating deployment element coupled to a distal end of the shaft. The tool is configured to provide an anchor storage area, which initially stores a plurality of tissue anchors, such that the inner shaft passes through channels of the anchors along entire longitudinal lengths of the anchors, and the anchors are within the outer tube. The rotating deployment element is configured to directly engage the anchors in the anchor storage area one at a time, advance each of the anchors while engaged in a distal direction, and deploy each of the anchors through the distal tube end and into tissue of a subject. Other embodiments are also described.
摘要翻译：锚定展开工具包括柔性外管，其中定位有柔性内轴，以及联接到轴的远端的旋转展开元件。该工具被配置成提供锚定储存区域，其最初存储多个组织锚固件，使得内部轴沿锚固件的整个纵向长度穿过锚定件的通道，并且锚定件在外部管中。旋转展开元件被构造成一次一个地直接接合锚定器存储区域中的锚固件，在远离方向接合时推进每个锚固件，并且将每个锚定件穿过远端管端部并且部署到主体的组织中。还描述了其它实施例。

5. 发明申请

US20120022557A1 MULTIPLE ANCHOR DELIVERY TOOL 有权
标题翻译：多个锚固器交付工具
公开(公告)号：US20120022557A1
公开(公告)日：2012-01-26
申请号：US12843412
申请日：2010-07-26
申请人： Oz CABIRI , Amir Gross , Tal Hammer , Tal Reich , Ehud Iflah
发明人： Oz CABIRI , Amir Gross , Tal Hammer , Tal Reich , Ehud Iflah
IPC分类号： A61B17/00
CPC分类号： A61B17/064 , A61B17/068 , A61B2017/0649 , A61F2/2445
摘要： An anchor deployment tool includes a flexible outer tube, within which is positioned a flexible inner shaft, and a rotating deployment element coupled to a distal end of the shaft. The tool is configured to provide an anchor storage area, which initially stores a plurality of tissue anchors, such that the inner shaft passes through channels of the anchors along entire longitudinal lengths of the anchors, and the anchors are within the outer tube. The rotating deployment element is configured to directly engage the anchors in the anchor storage area one at a time, advance each of the anchors while engaged in a distal direction, and deploy each of the anchors through the distal tube end and into tissue of a subject. Other embodiments are also described.
摘要翻译：锚定展开工具包括柔性外管，其中定位有柔性内轴，以及联接到轴的远端的旋转展开元件。该工具被配置成提供锚定储存区域，其最初存储多个组织锚固件，使得内部轴沿锚固件的整个纵向长度穿过锚定件的通道，并且锚定件在外部管中。旋转展开元件构造成一次一个地直接接合锚固储存区域中的锚固件，在远离方向接合时推进每个锚固件，并且将每个锚定件穿过远端管端部并且部署到受试者的组织中。还描述了其它实施例。

6. 发明申请

US20120136436A1 ADJUSTABLE ANNULOPLASTY DEVICES AND ADJUSTMENT MECHANISMS THEREFOR 有权
标题翻译：可调节的ANNULOPLASTY设备及其调整机制
公开(公告)号：US20120136436A1
公开(公告)日：2012-05-31
申请号：US13141606
申请日：2009-12-22
申请人： Oz Cabiri , Tal Sheps , Meir Kutzik , Amir Gross , Yossi Gross , Yuval Zipory
发明人： Oz Cabiri , Tal Sheps , Meir Kutzik , Amir Gross , Yossi Gross , Yuval Zipory
IPC分类号： A61F2/24
CPC分类号： A61F2/2445 , A61B17/0401 , A61B2017/00243 , A61B2017/0409 , A61B2017/0414 , A61B2017/0441 , A61B2017/0464 , A61B2017/0496 , A61B2017/0649 , A61B2017/12095 , A61F2/2442 , A61F2/2466 , A61F2250/0004 , A61F2250/001
摘要： Apparatus is provided including an implant structure (22, 122, 1122), a rotatable structure (2900) coupled to the implant structure (22, 122, 1122) in a vicinity of a first portion thereof, and a flexible member (30). At least a first portion of the 5 flexible member (30) is disposed in contact with the rotatable structure (2900), and at least one end portion of the flexible member (30) is not disposed in contact with the rotatable structure (30). In response to rotation of the rotatable structure (2900) in a first direction thereof, successive portions of the flexible member (30) contact the rotatable structure (2900) to pull the at least one end portion of the flexible member 0 (30) toward the first portion of the implant structure (22, 122, 1122), and responsively to draw the first and second portions of the implant structure (22, 122, 1122) toward each other. Other applications are also described.
摘要翻译：提供了包括植入结构（22,122,1122）的装置，在其第一部分附近与植入结构（22,122,1122）相连的可旋转结构（2900）和柔性构件（30）。所述柔性构件（30）的至少第一部分设置成与所述可旋转结构（2900）接触，并且所述柔性构件（30）的至少一个端部未设置成与所述可旋转结构（30）接触，。响应于可旋转结构（2900）沿其第一方向的旋转，柔性构件（30）的连续部分接触可旋转结构（2900）以将柔性构件0（30）的至少一个端部向着植入结构（22,122,1122）的第一部分，并且响应于将植入物结构（22,122,1122）的第一和第二部分彼此拉出。还描述了其它应用。

7. 发明授权

US08926696B2 Adjustable annuloplasty devices and adjustment mechanisms therefor 有权
标题翻译：可调式瓣环成形装置及其调节机构
公开(公告)号：US08926696B2
公开(公告)日：2015-01-06
申请号：US13141606
申请日：2009-12-22
申请人： Oz Cabiri , Tal Sheps , Meir Kutzik , Amir Gross , Yossi Gross , Yuval Zipory
发明人： Oz Cabiri , Tal Sheps , Meir Kutzik , Amir Gross , Yossi Gross , Yuval Zipory
IPC分类号： A61F2/24
CPC分类号： A61F2/2445 , A61B17/0401 , A61B2017/00243 , A61B2017/0409 , A61B2017/0414 , A61B2017/0441 , A61B2017/0464 , A61B2017/0496 , A61B2017/0649 , A61B2017/12095 , A61F2/2442 , A61F2/2466 , A61F2250/0004 , A61F2250/001
摘要： Apparatus is provided including an implant structure (22, 122, 1122), a rotatable structure (2900) coupled to the implant structure (22, 122, 1122) in a vicinity of a first portion thereof, and a flexible member (30). At least a first portion of the 5 flexible member (30) is disposed in contact with the rotatable structure (2900), and at least one end portion of the flexible member (30) is not disposed in contact with the rotatable structure (30). In response to rotation of the rotatable structure (2900) in a first direction thereof, successive portions of the flexible member (30) contact the rotatable structure (2900) to pull the at least one end portion of the flexible member 0 (30) toward the first portion of the implant structure (22, 122, 1122), and responsively to draw the first and second portions of the implant structure (22, 122, 1122) toward each other. Other applications are also described.
摘要翻译：提供了包括植入结构（22,122,1122）的装置，在其第一部分附近与植入结构（22,122,1122）相连的可旋转结构（2900）和柔性构件（30）。所述柔性构件（30）的至少第一部分设置成与所述可旋转结构（2900）接触，并且所述柔性构件（30）的至少一个端部未设置成与所述可旋转结构（30）接触，。响应于可旋转结构（2900）沿其第一方向的旋转，柔性构件（30）的连续部分接触可旋转结构（2900）以将柔性构件0（30）的至少一个端部向着植入结构（22,122,1122）的第一部分，并且响应于将植入物结构（22,122,1122）的第一和第二部分彼此拉出。还描述了其它应用。

8. 发明授权

US09277994B2 Implantation of repair chords in the heart 有权
标题翻译：在心脏植入修复和弦
公开(公告)号：US09277994B2
公开(公告)日：2016-03-08
申请号：US13319007
申请日：2010-05-04
申请人： Eran Miller , Oz Cabiri , Yossi Gross , Amir Gross , Tal Reich
发明人： Eran Miller , Oz Cabiri , Yossi Gross , Amir Gross , Tal Reich
IPC分类号： A61F2/24 , A61B17/04 , A61B17/00 , A61B17/064 , A61B17/12
CPC分类号： A61F2/2427 , A61B17/0401 , A61B2017/00243 , A61B2017/0409 , A61B2017/0414 , A61B2017/0441 , A61B2017/0464 , A61B2017/0496 , A61B2017/0649 , A61B2017/12095 , A61F2/2457 , A61F2/2466 , A61F2/2487
摘要： Apparatus is provided, including first and second longitudinal members coupled at respective first portions thereof to tissue surrounding the ventricle. The first portion of at least the first longitudinal member is coupled to a tissue anchor, and respective second portions of the first and second longitudinal members are coupled to respective first and second leaflets of a cardiac valve. The longitudinal members are arranged with respect to the tissue anchor and the portion of tissue surrounding the ventricle in a manner which facilitates adjustment of a degree of tension of the first and second longitudinal members to draw the first and second leaflets together. A longitudinal-member-coupling device is coupled to the first and second longitudinal members, and is advanceable toward a ventricular surface of the first and second leaflets, and responsively to draw together the first and second longitudinal members. Other applications are also described.
摘要翻译：提供了包括在其相应的第一部分处耦合到围绕心室的组织的第一和第二纵向构件的装置。至少第一纵向构件的第一部分联接到组织锚，并且第一和第二纵向构件的相应的第二部分联接到心脏瓣膜的相应的第一和第二小叶。纵向构件以便于调整第一和第二纵向构件的张力程度以将第一和第二传单牵引在一起的方式相对于组织锚和围绕心室的组织的部分布置。纵向构件联接装置联接到第一和第二纵向构件，并且可朝向第一和第二小叶的心室表面前进，并且响应地将第一和第二纵向构件汇合在一起。还描述了其它应用。

9. 发明申请

US20140094903A1 IMPLANTATION OF REPAIR CHORDS IN THE HEART 有权
标题翻译：在心脏植入修复术语
公开(公告)号：US20140094903A1
公开(公告)日：2014-04-03
申请号：US13319007
申请日：2010-05-04
申请人： Eran Miller , Oz Cabiri , Yossi Gross , Amir Gross , Tal Reich
发明人： Eran Miller , Oz Cabiri , Yossi Gross , Amir Gross , Tal Reich
IPC分类号： A61F2/24
CPC分类号： A61F2/2427 , A61B17/0401 , A61B2017/00243 , A61B2017/0409 , A61B2017/0414 , A61B2017/0441 , A61B2017/0464 , A61B2017/0496 , A61B2017/0649 , A61B2017/12095 , A61F2/2457 , A61F2/2466 , A61F2/2487
摘要： Apparatus is provided, including first and second longitudinal members coupled at respective first portions thereof to tissue surrounding the ventricle. The first portion of at least the first longitudinal member is coupled to a tissue anchor, and respective second portions of the first and second longitudinal members are coupled to respective first and second leaflets of a cardiac valve. The longitudinal members are arranged with respect to the tissue anchor and the portion of tissue surrounding the ventricle in a manner which facilitates adjustment of a degree of tension of the first and second longitudinal members to draw the first and second leaflets together. A longitudinal-member-coupling device is coupled to the first and second longitudinal members, and is advanceable toward a ventricular surface of the first and second leaflets, and responsively to draw together the first and second longitudinal members. Other applications are also described.
摘要翻译：提供了包括在其相应的第一部分处耦合到围绕心室的组织的第一和第二纵向构件的装置。至少第一纵向构件的第一部分联接到组织锚，并且第一和第二纵向构件的相应的第二部分联接到心脏瓣膜的相应的第一和第二小叶。纵向构件以便于调整第一和第二纵向构件的张力程度以将第一和第二传单牵引在一起的方式相对于组织锚和围绕心室的组织的部分布置。纵向构件联接装置联接到第一和第二纵向构件，并且可朝向第一和第二小叶的心室表面前进，并且响应地将第一和第二纵向构件汇合在一起。还描述了其它应用。

10. 发明授权

US08545553B2 Over-wire rotation tool 有权
标题翻译：过线旋转工具
公开(公告)号：US08545553B2
公开(公告)日：2013-10-01
申请号：US12689635
申请日：2010-01-19
申请人： Yuval Zipory , Tal Hammer , Yossi Gross , Amir Gross , Oz Cabiri , Francesco Maisano , Eran Miller
发明人： Yuval Zipory , Tal Hammer , Yossi Gross , Amir Gross , Oz Cabiri , Francesco Maisano , Eran Miller
IPC分类号： A61F2/24 , A61M5/32 , A61B17/10 , A61B17/08
CPC分类号： A61F2/2436 , A61B17/00234 , A61B17/0401 , A61B17/064 , A61B17/068 , A61B17/072 , A61B2017/00243 , A61B2017/0409 , A61B2017/0414 , A61B2017/0441 , A61B2017/0443 , A61B2017/0464 , A61B2017/0496 , A61B2017/0647 , A61B2017/0648 , A61B2017/0649 , A61B2017/12095 , A61B2017/2923 , A61F2/2409 , A61F2/2412 , A61F2/2445 , A61F2/2451 , A61F2/2457 , A61F2/2466 , A61F2002/30537 , A61F2220/0016 , A61F2250/0004
摘要： Apparatus is provided that includes an implant structure, which includes a contracting mechanism, which includes a rotatable structure, arranged such that rotation of the rotatable structure contracts the implant structure. A longitudinal member is coupled to the contracting mechanism. A tool for rotating the rotatable structure is configured to be guided along the longitudinal member, to engage the rotatable structure, and to rotate the rotatable structure in response to a rotational force applied to the tool. Other embodiments are also described.
摘要翻译：提供了包括植入物结构的装置，其包括收缩机构，该收缩机构包括可旋转结构，其布置成使得可旋转结构的旋转使植入物结构收缩。纵向构件联接到收缩机构。用于旋转可旋转结构的工具被配置为沿着纵向构件被引导以接合可旋转结构，并且响应于施加到工具的旋转力而旋转可旋转结构。还描述了其它实施例。

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