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1. 发明申请

US20140142695A1 CONTRACTIBLE ANNULOPLASTY STRUCTURES 有权
标题翻译：可逆性鼻咽结构
公开(公告)号：US20140142695A1
公开(公告)日：2014-05-22
申请号：US14128756
申请日：2012-06-21
申请人： Amir Gross , Tal Sheps , Tal Hammer , Tal Reich , Ehud Iflah , Uriel Aba Pomerantz , Oz Cabiri , Yaron Herman
发明人： Amir Gross , Tal Sheps , Tal Hammer , Tal Reich , Ehud Iflah , Uriel Aba Pomerantz , Oz Cabiri , Yaron Herman
IPC分类号： A61F2/24
CPC分类号： A61F2/2445 , A61B17/068 , A61B17/072 , A61B2017/00243 , A61B2017/003 , A61B2017/0649 , A61F2/2448 , A61F2/2466 , A61F2250/0004
摘要： Apparatus is provided including an implantable structure (22), including a flexible sleeve (26), having first and second sleeve ends (49, 51), a contracting assembly (40), which is configured to longitudinally contract the sleeve (26). The contracting assembly (40) includes a contracting mechanism (28), which is at a first site of the sleeve (26); and a longitudinal contracting member (30), having (a) a first member end, (b) a second member end (53), coupled to the sleeve (26) at a second site longitudinally between the first site and the second sleeve end (49 or 51), exclusive. A force-distributing element (540) is couplable to the sleeve (26) in a vicinity of the second sleeve end (49 or 51), element (540) is configured to distribute a contraction force by the contracting member (30) between the second member end (53) and the second sleeve end (49 or 51). Other applications are also described.
摘要翻译：提供了包括可植入结构（22）的装置，其包括具有第一和第二套筒端部（49,51）的柔性套筒（26），收缩组件（40），其构造成纵向收缩套筒（26）。收缩组件（40）包括在套筒（26）的第一位置处的收缩机构（28）; 和纵向收缩构件（30），其具有（a）第一构件端部，（b）第二构件端部（53），其在第一位置和第二套筒端部之间的第二位置处连接到套筒（26）（49或51），独家。力分配元件（540）可在第二套筒端部（49或51）附近与套筒（26）连接，元件（540）构造成将收缩构件（30）的收缩力分配在第二构件端部（53）和第二套筒端部（49或51）。还描述了其它应用。

2. 发明授权

US08523881B2 Multiple anchor delivery tool 有权
标题翻译：多锚定传送工具
公开(公告)号：US08523881B2
公开(公告)日：2013-09-03
申请号：US12843412
申请日：2010-07-26
申请人： Oz Cabiri , Amir Gross , Tal Hammer , Tal Reich , Ehud Iflah
发明人： Oz Cabiri , Amir Gross , Tal Hammer , Tal Reich , Ehud Iflah
IPC分类号： A61B17/10
CPC分类号： A61B17/064 , A61B17/068 , A61B2017/0649 , A61F2/2445
摘要： An anchor deployment tool includes a flexible outer tube, within which is positioned a flexible inner shaft, and a rotating deployment element coupled to a distal end of the shaft. The tool is configured to provide an anchor storage area, which initially stores a plurality of tissue anchors, such that the inner shaft passes through channels of the anchors along entire longitudinal lengths of the anchors, and the anchors are within the outer tube. The rotating deployment element is configured to directly engage the anchors in the anchor storage area one at a time, advance each of the anchors while engaged in a distal direction, and deploy each of the anchors through the distal tube end and into tissue of a subject. Other embodiments are also described.
摘要翻译：锚定展开工具包括柔性外管，其中定位有柔性内轴，以及联接到轴的远端的旋转展开元件。该工具被配置成提供锚定储存区域，其最初存储多个组织锚固件，使得内部轴沿锚固件的整个纵向长度穿过锚定件的通道，并且锚定件在外部管中。旋转展开元件被构造成一次一个地直接接合锚定器存储区域中的锚固件，在远离方向接合时推进每个锚固件，并且将每个锚定件穿过远端管端部并且部署到主体的组织中。还描述了其它实施例。

3. 发明授权

US09011530B2 Partially-adjustable annuloplasty structure 有权
标题翻译：部分可调环形成形术结构
公开(公告)号：US09011530B2
公开(公告)日：2015-04-21
申请号：US13167444
申请日：2011-06-23
申请人： Tal Reich , Tal Hammer , Uriel Aba Pomerantz , Oz Cabiri
发明人： Tal Reich , Tal Hammer , Uriel Aba Pomerantz , Oz Cabiri
IPC分类号： A61F2/24 , A61B17/072 , A61B17/068 , A61B17/00 , A61B17/064
CPC分类号： A61F2/2445 , A61B17/068 , A61B17/072 , A61B2017/00243 , A61B2017/003 , A61B2017/0649 , A61F2/2448 , A61F2/2466 , A61F2250/0004
摘要： Apparatus and methods are described including an annuloplasty structure configured for implantation along an annulus of an atrioventricular valve of a heart of a subject. The structure includes a coiled element comprising at least one first portion thereof which is flexible and longitudinally compressible, and at least one second portion thereof in series with the first portion, the second portion being flexible and less longitudinally compressible than the first portion. Other applications are also described.
摘要翻译：描述了包括瓣膜成形术结构的装置和方法，所述瓣膜成形术结构被构造用于沿着受试者心脏的房室瓣的环进行植入。该结构包括一个螺旋元件，其包括至少一个第一部分，该第一部分是柔性的并且纵向可压缩的，并且其至少一个第二部分与第一部分串联，第二部分是柔性的并且比第一部分更不易纵向压缩。还描述了其它应用。

4. 发明申请

US20120136436A1 ADJUSTABLE ANNULOPLASTY DEVICES AND ADJUSTMENT MECHANISMS THEREFOR 有权
标题翻译：可调节的ANNULOPLASTY设备及其调整机制
公开(公告)号：US20120136436A1
公开(公告)日：2012-05-31
申请号：US13141606
申请日：2009-12-22
申请人： Oz Cabiri , Tal Sheps , Meir Kutzik , Amir Gross , Yossi Gross , Yuval Zipory
发明人： Oz Cabiri , Tal Sheps , Meir Kutzik , Amir Gross , Yossi Gross , Yuval Zipory
IPC分类号： A61F2/24
CPC分类号： A61F2/2445 , A61B17/0401 , A61B2017/00243 , A61B2017/0409 , A61B2017/0414 , A61B2017/0441 , A61B2017/0464 , A61B2017/0496 , A61B2017/0649 , A61B2017/12095 , A61F2/2442 , A61F2/2466 , A61F2250/0004 , A61F2250/001
摘要： Apparatus is provided including an implant structure (22, 122, 1122), a rotatable structure (2900) coupled to the implant structure (22, 122, 1122) in a vicinity of a first portion thereof, and a flexible member (30). At least a first portion of the 5 flexible member (30) is disposed in contact with the rotatable structure (2900), and at least one end portion of the flexible member (30) is not disposed in contact with the rotatable structure (30). In response to rotation of the rotatable structure (2900) in a first direction thereof, successive portions of the flexible member (30) contact the rotatable structure (2900) to pull the at least one end portion of the flexible member 0 (30) toward the first portion of the implant structure (22, 122, 1122), and responsively to draw the first and second portions of the implant structure (22, 122, 1122) toward each other. Other applications are also described.
摘要翻译：提供了包括植入结构（22,122,1122）的装置，在其第一部分附近与植入结构（22,122,1122）相连的可旋转结构（2900）和柔性构件（30）。所述柔性构件（30）的至少第一部分设置成与所述可旋转结构（2900）接触，并且所述柔性构件（30）的至少一个端部未设置成与所述可旋转结构（30）接触，。响应于可旋转结构（2900）沿其第一方向的旋转，柔性构件（30）的连续部分接触可旋转结构（2900）以将柔性构件0（30）的至少一个端部向着植入结构（22,122,1122）的第一部分，并且响应于将植入物结构（22,122,1122）的第一和第二部分彼此拉出。还描述了其它应用。

5. 发明申请

US20100161043A1 IMPLANTATION OF REPAIR CHORDS IN THE HEART 有权
标题翻译：在心脏植入修复术语
公开(公告)号：US20100161043A1
公开(公告)日：2010-06-24
申请号：US12563952
申请日：2009-09-21
申请人： Francesco Maisano , Eran Miller , Oz Cabiri , Yaron Herman , Yoseph Weitzman , Yossi Gross , Tal Sheps
发明人： Francesco Maisano , Eran Miller , Oz Cabiri , Yaron Herman , Yoseph Weitzman , Yossi Gross , Tal Sheps
IPC分类号： A61F2/24
CPC分类号： A61F2/2466 , A61B17/0401 , A61B17/122 , A61B2017/00243 , A61B2017/0406 , A61B2017/0409 , A61B2017/0414 , A61B2017/0441 , A61B2017/0464 , A61B2017/0496 , A61F2/2457 , A61F2/2487 , A61F2250/0007
摘要： Apparatus is provided for adjusting at least one dimension of an implant, including a rotatable structure having first and second openings and a channel extending between the first and second openings. The channel allows passage therethrough of an elongate tool. The second end of the structure has a lower surface having one or more recesses along a circumference thereof. A mechanical element provides a protrusion that is disposed within one of the recesses of the rotatable structure during a resting state of the mechanical element, in a manner that restricts rotation of the rotatable structure. The mechanical clement comprises a depressible portion coupled to the protrusion disposed in communication with the second opening of the lower surface, and configured to dislodge the protrusion from within the recess in response to a force applied thereto by the elongate tool. Other applications are also described.
摘要翻译：提供了用于调节植入物的至少一个维度的装置，包括具有第一和第二开口的可旋转结构以及在第一和第二开口之间延伸的通道。通道允许细长工具通过。该结构的第二端具有沿其圆周具有一个或多个凹部的下表面。机械元件以限制可旋转结构的旋转的方式提供在机械元件的静止状态下设置在可旋转结构的一个凹部内的突起。机械部件包括联接到突起的可压下部分，所述突起设置成与下表面的第二开口连通，并且被构造成响应于由细长工具施加到其上的力而从凹部内移除突出部。还描述了其它应用。

6. 发明授权

US08252050B2 Implantation of repair chords in the heart 有权
标题翻译：在心脏植入修复和弦
公开(公告)号：US08252050B2
公开(公告)日：2012-08-28
申请号：US12563952
申请日：2009-09-21
申请人： Francesco Maisano , Eran Miller , Oz Cabiri , Yaron Herman , Yoseph Weitzman , Yossi Gross , Tal Sheps
发明人： Francesco Maisano , Eran Miller , Oz Cabiri , Yaron Herman , Yoseph Weitzman , Yossi Gross , Tal Sheps
IPC分类号： A61F2/24
CPC分类号： A61F2/2466 , A61B17/0401 , A61B17/122 , A61B2017/00243 , A61B2017/0406 , A61B2017/0409 , A61B2017/0414 , A61B2017/0441 , A61B2017/0464 , A61B2017/0496 , A61F2/2457 , A61F2/2487 , A61F2250/0007
摘要： Apparatus is provided for adjusting at least one dimension of an implant, including a rotatable structure having first and second openings and a channel extending between the first and second openings. The channel allows passage therethrough of an elongate tool. The second end of the structure has a lower surface having one or more recesses along a circumference thereof. A mechanical element provides a protrusion that is disposed within one of the recesses of the rotatable structure during a resting state of the mechanical element, in a manner that restricts rotation of the rotatable structure. The mechanical element includes a depressible portion coupled to the protrusion disposed in communication with the second opening of the lower surface, and configured to dislodge the protrusion from within the recess in response to a force applied thereto by the elongate tool. Other applications are also described.
摘要翻译：提供了用于调节植入物的至少一个维度的装置，包括具有第一和第二开口的可旋转结构以及在第一和第二开口之间延伸的通道。通道允许细长工具通过。该结构的第二端具有沿其圆周具有一个或多个凹部的下表面。机械元件以限制可旋转结构的旋转的方式提供在机械元件的静止状态下设置在可旋转结构的一个凹部内的突起。所述机械元件包括联接到所述突起的可压下部分，所述突起设置成与所述下表面的第二开口连通，并且被配置为响应于由所述细长工具施加到所述凹部的力而从所述凹部内移除所述突起。还描述了其它应用。

7. 发明授权

US08926696B2 Adjustable annuloplasty devices and adjustment mechanisms therefor 有权
标题翻译：可调式瓣环成形装置及其调节机构
公开(公告)号：US08926696B2
公开(公告)日：2015-01-06
申请号：US13141606
申请日：2009-12-22
申请人： Oz Cabiri , Tal Sheps , Meir Kutzik , Amir Gross , Yossi Gross , Yuval Zipory
发明人： Oz Cabiri , Tal Sheps , Meir Kutzik , Amir Gross , Yossi Gross , Yuval Zipory
IPC分类号： A61F2/24
CPC分类号： A61F2/2445 , A61B17/0401 , A61B2017/00243 , A61B2017/0409 , A61B2017/0414 , A61B2017/0441 , A61B2017/0464 , A61B2017/0496 , A61B2017/0649 , A61B2017/12095 , A61F2/2442 , A61F2/2466 , A61F2250/0004 , A61F2250/001
摘要： Apparatus is provided including an implant structure (22, 122, 1122), a rotatable structure (2900) coupled to the implant structure (22, 122, 1122) in a vicinity of a first portion thereof, and a flexible member (30). At least a first portion of the 5 flexible member (30) is disposed in contact with the rotatable structure (2900), and at least one end portion of the flexible member (30) is not disposed in contact with the rotatable structure (30). In response to rotation of the rotatable structure (2900) in a first direction thereof, successive portions of the flexible member (30) contact the rotatable structure (2900) to pull the at least one end portion of the flexible member 0 (30) toward the first portion of the implant structure (22, 122, 1122), and responsively to draw the first and second portions of the implant structure (22, 122, 1122) toward each other. Other applications are also described.
摘要翻译：提供了包括植入结构（22,122,1122）的装置，在其第一部分附近与植入结构（22,122,1122）相连的可旋转结构（2900）和柔性构件（30）。所述柔性构件（30）的至少第一部分设置成与所述可旋转结构（2900）接触，并且所述柔性构件（30）的至少一个端部未设置成与所述可旋转结构（30）接触，。响应于可旋转结构（2900）沿其第一方向的旋转，柔性构件（30）的连续部分接触可旋转结构（2900）以将柔性构件0（30）的至少一个端部向着植入结构（22,122,1122）的第一部分，并且响应于将植入物结构（22,122,1122）的第一和第二部分彼此拉出。还描述了其它应用。

8. 发明授权

US09277994B2 Implantation of repair chords in the heart 有权
标题翻译：在心脏植入修复和弦
公开(公告)号：US09277994B2
公开(公告)日：2016-03-08
申请号：US13319007
申请日：2010-05-04
申请人： Eran Miller , Oz Cabiri , Yossi Gross , Amir Gross , Tal Reich
发明人： Eran Miller , Oz Cabiri , Yossi Gross , Amir Gross , Tal Reich
IPC分类号： A61F2/24 , A61B17/04 , A61B17/00 , A61B17/064 , A61B17/12
CPC分类号： A61F2/2427 , A61B17/0401 , A61B2017/00243 , A61B2017/0409 , A61B2017/0414 , A61B2017/0441 , A61B2017/0464 , A61B2017/0496 , A61B2017/0649 , A61B2017/12095 , A61F2/2457 , A61F2/2466 , A61F2/2487
摘要： Apparatus is provided, including first and second longitudinal members coupled at respective first portions thereof to tissue surrounding the ventricle. The first portion of at least the first longitudinal member is coupled to a tissue anchor, and respective second portions of the first and second longitudinal members are coupled to respective first and second leaflets of a cardiac valve. The longitudinal members are arranged with respect to the tissue anchor and the portion of tissue surrounding the ventricle in a manner which facilitates adjustment of a degree of tension of the first and second longitudinal members to draw the first and second leaflets together. A longitudinal-member-coupling device is coupled to the first and second longitudinal members, and is advanceable toward a ventricular surface of the first and second leaflets, and responsively to draw together the first and second longitudinal members. Other applications are also described.
摘要翻译：提供了包括在其相应的第一部分处耦合到围绕心室的组织的第一和第二纵向构件的装置。至少第一纵向构件的第一部分联接到组织锚，并且第一和第二纵向构件的相应的第二部分联接到心脏瓣膜的相应的第一和第二小叶。纵向构件以便于调整第一和第二纵向构件的张力程度以将第一和第二传单牵引在一起的方式相对于组织锚和围绕心室的组织的部分布置。纵向构件联接装置联接到第一和第二纵向构件，并且可朝向第一和第二小叶的心室表面前进，并且响应地将第一和第二纵向构件汇合在一起。还描述了其它应用。

9. 发明申请

US20140094903A1 IMPLANTATION OF REPAIR CHORDS IN THE HEART 有权
标题翻译：在心脏植入修复术语
公开(公告)号：US20140094903A1
公开(公告)日：2014-04-03
申请号：US13319007
申请日：2010-05-04
申请人： Eran Miller , Oz Cabiri , Yossi Gross , Amir Gross , Tal Reich
发明人： Eran Miller , Oz Cabiri , Yossi Gross , Amir Gross , Tal Reich
IPC分类号： A61F2/24
CPC分类号： A61F2/2427 , A61B17/0401 , A61B2017/00243 , A61B2017/0409 , A61B2017/0414 , A61B2017/0441 , A61B2017/0464 , A61B2017/0496 , A61B2017/0649 , A61B2017/12095 , A61F2/2457 , A61F2/2466 , A61F2/2487
摘要： Apparatus is provided, including first and second longitudinal members coupled at respective first portions thereof to tissue surrounding the ventricle. The first portion of at least the first longitudinal member is coupled to a tissue anchor, and respective second portions of the first and second longitudinal members are coupled to respective first and second leaflets of a cardiac valve. The longitudinal members are arranged with respect to the tissue anchor and the portion of tissue surrounding the ventricle in a manner which facilitates adjustment of a degree of tension of the first and second longitudinal members to draw the first and second leaflets together. A longitudinal-member-coupling device is coupled to the first and second longitudinal members, and is advanceable toward a ventricular surface of the first and second leaflets, and responsively to draw together the first and second longitudinal members. Other applications are also described.
摘要翻译：提供了包括在其相应的第一部分处耦合到围绕心室的组织的第一和第二纵向构件的装置。至少第一纵向构件的第一部分联接到组织锚，并且第一和第二纵向构件的相应的第二部分联接到心脏瓣膜的相应的第一和第二小叶。纵向构件以便于调整第一和第二纵向构件的张力程度以将第一和第二传单牵引在一起的方式相对于组织锚和围绕心室的组织的部分布置。纵向构件联接装置联接到第一和第二纵向构件，并且可朝向第一和第二小叶的心室表面前进，并且响应地将第一和第二纵向构件汇合在一起。还描述了其它应用。

10. 发明授权

US08911494B2 Deployment techniques for annuloplasty ring 有权
标题翻译：瓣环成形术的部署技术
公开(公告)号：US08911494B2
公开(公告)日：2014-12-16
申请号：US12689693
申请日：2010-01-19
申请人： Tal Hammer , Yuval Zipory , Yoseph Weitzman , Amir Gross , Oz Cabiri , Aram Ayvazian
发明人： Tal Hammer , Yuval Zipory , Yoseph Weitzman , Amir Gross , Oz Cabiri , Aram Ayvazian
IPC分类号： A61F2/24 , A61B17/04 , A61B17/064 , A61B17/068 , A61B17/00 , A61B17/12 , A61B17/29 , A61F2/30
CPC分类号： A61F2/2436 , A61B17/00234 , A61B17/0401 , A61B17/064 , A61B17/068 , A61B17/072 , A61B2017/00243 , A61B2017/0409 , A61B2017/0414 , A61B2017/0441 , A61B2017/0443 , A61B2017/0464 , A61B2017/0496 , A61B2017/0647 , A61B2017/0648 , A61B2017/0649 , A61B2017/12095 , A61B2017/2923 , A61F2/2409 , A61F2/2412 , A61F2/2445 , A61F2/2451 , A61F2/2457 , A61F2/2466 , A61F2002/30537 , A61F2220/0016 , A61F2250/0004
摘要： An anchor driver is provided that includes a driver head having a flexible ring. An anchor is provided that includes a coupling head, which is shaped so as to define: (a) one or more mating elements that engage mechanical coupling elements of the driver head such that rotation of the mechanical coupling elements rotates the mating elements, which in turn rotate the coupling head, and (b) an outer coupling surface, sized to be inserted into and engage the flexible ring. The anchor also includes a tissue coupling element fixed to the coupling head. The rotation of the mechanical coupling elements causes the tissue coupling element of the anchor to screw itself into tissue, thereby causing separation of: (a) the outer coupling surface of the coupling head from the flexible ring, and (b) the mating elements of the coupling head from the corresponding mechanical coupling elements. Other embodiments are also described.
摘要翻译：提供一种锚驱动器，其包括具有柔性环的驱动头。提供了一种锚，其包括联接头，该联接头被成形为限定：（a）一个或多个匹配元件，其接合驾驶员头部的机械联接元件，使得机械联接元件的旋转使配合元件旋转，旋转联接头，和（b）外部联接表面，其尺寸被设计成插入并接合柔性环。锚固件还包括固定到联接头的组织连接元件。机械联接元件的旋转导致锚固件的组织连接元件将自身螺钉自身拧入组织中，从而分离出：（a）联接头的外部联接表面与柔性环的分离，以及（b）联接头从相应的机械耦合元件。还描述了其它实施例。

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