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1. 发明授权

US4706188A Method and apparatus for reading samples of a time-dependent signal in a data processing system 失效
标题翻译：用于在数据处理系统中读取时间相关信号的样本的方法和装置
公开(公告)号：US4706188A
公开(公告)日：1987-11-10
申请号：US698854
申请日：1985-02-06
申请人： Alois Rainer , Walter Ulbrich , Lajos Gazsi
发明人： Alois Rainer , Walter Ulbrich , Lajos Gazsi
IPC分类号： H03H15/00 , G06F3/05 , G06F17/10 , H03H17/02 , H03H21/00 , H04B3/04 , G06F12/02
CPC分类号： G06F3/05
摘要： A method and apparatus for preparing samples of a time-dependent signal (Se) in a data processing system which comprises an arithmetic unity (1), a control unit (2), a memory (3) and an address modification unit (13) wherein with a stored dataset of individual samples, for updating these step-by-step during every successive sampling period and respectively reading out the dated dataset and supplying it to the arithmetic unit (1), is achieved such that an address sequence which traverses a prescribed memory area is output via the address modification unit (13), so that a sequence of samples is written. Subsequently, the memory area is cyclically traversed with a plurality of address strings, whereby the stored samples are successively read out onto a bus line (4) and, when reaching an individual memory location within each of the address strings, the oldest sample stored there is overwritten by a further sample. The method is distinguished by a minimum of re-storing operations. The invention is used in signal processors, particularly those for filtering jobs.
摘要翻译：一种用于在包括算术单位（1），控制单元（2），存储器（3）和地址修改单元（13）的数据处理系统中准备时间相关信号（Se）的样本的方法和装置，其中利用存储的各个样本的数据集，用于在每个连续采样周期期间逐步更新这些数据集，并分别读出已注册的数据集并将其提供给算术单元（1），以使得经过通过地址修改单元（13）输出规定的存储区域，从而写入样本序列。随后，存储区域被循环地遍历多个地址串，由此存储的样本被连续地读出到总线（4）上，并且当到达每个地址串中的单个存储器位置时，存储在那里的最旧的样本被另一个样本覆盖。该方法通过最少的重新存储操作来区分。本发明用于信号处理器，特别是用于过滤作业的处理器。

2. 发明授权

US4675837A Digital arithmetic unit having shortened processing time and a simplified structure 失效
标题翻译：具有缩短处理时间和简化结构的数字运算单元
公开(公告)号：US4675837A
公开(公告)日：1987-06-23
申请号：US619185
申请日：1984-06-11
申请人： Walter Ulbrich , Alois Rainer , Tobias Noll
发明人： Walter Ulbrich , Alois Rainer , Tobias Noll
IPC分类号： G06F7/505 , G06F7/50 , G06F7/507 , G06F7/508 , G06F7/52
CPC分类号： G06F7/507
摘要： A digital arithmetic unit useful in data processing digital circuits comprises a plurality of stages each having two half-adders combined into a full adder and a carry logic element. An objective is to shorten the processing time for the addition and subtraction of binary numbers. For this purpose, the stages are divided into at least two groups and two separate carry paths are provided within each group. One of the carry paths is only switched on by means of selection logic elements. The activation occurs sequentially in group-wise fashion after simultaneous carry runs in all carry paths. The advantage particularly consists of the chronological coincidence of the carry runs in all groups.
摘要翻译：用于数据处理数字电路的数字运算单元包括多个级，每个级具有组合成全加器和进位逻辑元件的两个加法器。目的是缩短加法和减法二进制数的处理时间。为此，将这些阶段划分为至少两组，并在每组内提供两个单独的进位路径。其中一个进位路径仅通过选择逻辑元件接通。在所有携带路径中同时进行运行之后，以分组方式依次进行激活。这个优点特别包括所有组的进位运行的时间顺序。

3. 发明申请

US20060000712A1 Separation method and device for protein mixtures 失效
标题翻译：蛋白质混合物的分离方法和装置
公开(公告)号：US20060000712A1
公开(公告)日：2006-01-05
申请号：US11120098
申请日：2005-05-02
申请人： Hans-Joachim Hoeltke , Albert Roeder , Alois Rainer , Peter Berndt , Carlo Effenhauser , Hanno Langen , Remo Hochstrasser
发明人： Hans-Joachim Hoeltke , Albert Roeder , Alois Rainer , Peter Berndt , Carlo Effenhauser , Hanno Langen , Remo Hochstrasser
IPC分类号： B01D57/02 , C02F1/40
CPC分类号： G01N27/44773
摘要： A separation device and a separation method for biomolecular sample material and in particular protein mixtures. For this purpose a separation element 10 for the two-dimensional and preferable electrophoretic separation of components of the sample material is provided in area 30 of a separation plane. According to the invention it is proposed that the separation element 10 has a channel or transfer structure 14 for the locally resolved discharge of separated sample components in a transport direction that is at right angles to the separation plane onto a support surface 16 that is preferably suitable for mass spectroscopic analyses.
摘要翻译：用于生物分子样品材料，特别是蛋白质混合物的分离装置和分离方法。为此，在分离平面的区域30中提供用于样品材料的组分的二维和优选的电泳分离的分离元件10。根据本发明，提出了分离元件10具有通道或转移结构14，用于将分离的样品组分在与分离平面成直角的运输方向上局部分解排放到支撑表面16上，其优选地适合用于质谱分析。

4. 发明授权

US4679165A Multiplication unit and method for the operation thereof 失效
标题翻译：乘法单元及其操作方法
公开(公告)号：US4679165A
公开(公告)日：1987-07-07
申请号：US628585
申请日：1984-07-06
申请人： Alois Rainer
发明人： Alois Rainer
IPC分类号： G06F7/53 , G06F7/52 , G06F7/527 , G06F7/54
CPC分类号： G06F7/5338
摘要： A multiplication unit for n-place binary numbers has a first register containing the multiplicand, and accumulator, and an arithmetic unit having operand inputs connected to the first register and to the accumulator. The operation to be undertaken by the arithmetic unit is to find by the bits of a multiplier which is contained in a second register, the second register being connected to an operation instruction input of the arithmetic unit. A multiplexer having inputs connected to the outputs of the second register through-connects the bits of five adjacent multiplier places to the inputs of a logic circuit, which derives the operation instruction for the arithmetic unit. The logic circuit also supplies an instruction to a mulitple shift unit interconnected between the output of the arithmetic unit and the input of the accumulator.
摘要翻译：用于n位二进制数的乘法单元具有包含被乘数和累加器的第一寄存器，以及具有连接到第一寄存器和累加器的操作数输入的算术单元。由算术单元进行的操作是通过包含在第二寄存器中的乘法器的位来查找第二寄存器，其连接到运算单元的操作指令输入。具有连接到第二寄存器的输出的输入的多路复用器通过将五个相邻乘法器位的位连接到逻辑电路的输入，该逻辑电路的输入导出运算单元的操作指令。逻辑电路还向在运算单元的输出和累加器的输入之间互连的多个移位单元提供指令。

5. 外观设计

USD677400S1 Pipette tip plate 有权
标题翻译：移液器吸头板
公开(公告)号：USD677400S1
公开(公告)日：2013-03-05
申请号：US29368504
申请日：2010-08-25
申请人： Thomas Blaettler , Alois Rainer , Armin Bucher
设计人： Thomas Blaettler , Alois Rainer , Armin Bucher

6. 发明授权

US07645369B2 Separation method and device for protein mixtures 失效
标题翻译：蛋白质混合物的分离方法和装置
公开(公告)号：US07645369B2
公开(公告)日：2010-01-12
申请号：US11120098
申请日：2005-05-02
申请人： Hans-Joachim Hoeltke , Albert Roeder , Alois Rainer , Peter Berndt , Carlo Effenhauser , Hanno Langen , Remo Anton Hochstrasser
发明人： Hans-Joachim Hoeltke , Albert Roeder , Alois Rainer , Peter Berndt , Carlo Effenhauser , Hanno Langen , Remo Anton Hochstrasser
IPC分类号： G01N27/447 , G01N27/453
CPC分类号： G01N27/44773
摘要： A separation device and a separation method for biomolecular sample material and in particular protein mixtures. For this purpose a separation element 10 for the two-dimensional and preferable electrophoretic separation of components of the sample material is provided in area 30 of a separation plane. According to the invention it is proposed that the separation element 10 has a channel or transfer structure 14 for the locally resolved discharge of separated sample components in a transport direction that is at right angles to the separation plane onto a support surface 16 that is preferably suitable for mass spectroscopic analyses.
摘要翻译：用于生物分子样品材料，特别是蛋白质混合物的分离装置和分离方法。为此，在分离平面的区域30中提供用于样品材料的组分的二维和优选的电泳分离的分离元件10。根据本发明，提出了分离元件10具有通道或转移结构14，用于将分离的样品组分在与分离平面成直角的运输方向上局部分解排放到支撑表面16上，其优选地适合用于质谱分析。

7. 发明授权

US08951780B2 Method and device for purifying nucleic acids 有权
标题翻译：核酸纯化方法和装置
公开(公告)号：US08951780B2
公开(公告)日：2015-02-10
申请号：US12261476
申请日：2008-10-30
申请人： Maximilian Ruhstorfer , Bernd Buchberger , Horst Donner , Alois Rainer
发明人： Maximilian Ruhstorfer , Bernd Buchberger , Horst Donner , Alois Rainer
IPC分类号： C12M3/00 , B01L3/00 , B01D29/05
CPC分类号： B01L3/508 , B01D29/05 , B01L3/502 , B01L3/5021 , B01L2200/0631 , B01L2300/0681 , B01L2300/069
摘要： The invention concerns a method for isolating and purifying nucleic acids from large sample volumes and a device suitable for this. The device comprises a funnel, a separating column, and a tab which are detachable from each other. The method according to the invention in which the device according to the invention is used ensures a higher yield of nucleic acids.
摘要翻译：本发明涉及从大样品体积分离和纯化核酸的方法以及适用于此的装置。该装置包括可以彼此分离的漏斗，分离柱和突片。根据本发明的方法，其中使用根据本发明的装置确保较高的核酸产量。

8. 发明授权

US08157746B2 Device for cutting out tissue specimens 失效
标题翻译：切割组织标本的装置
公开(公告)号：US08157746B2
公开(公告)日：2012-04-17
申请号：US11272187
申请日：2005-11-10
申请人： Walter Eberle , Peter Hloch , Christoph Hundt , Alois Rainer
发明人： Walter Eberle , Peter Hloch , Christoph Hundt , Alois Rainer
IPC分类号： A61B10/00 , A61B17/32 , A61B17/14
CPC分类号： A61B17/32053 , A61B10/0233
摘要： The present invention relates to a device for separating a tissue part from brain material, the device comprising a circular blade which continues as the wall of a cylindrical or substantially cylindrical hollow body, at the end of which a grid is arranged perpendicular to the cylinder axis. The invention further relates to the use of the device in a method for separating a tissue part from brain material and to a kit containing one or more devices according to the invention.
摘要翻译：本发明涉及一种用于从脑材料中分离组织部分的装置，该装置包括圆形叶片，该圆形叶片作为圆柱形或基本上圆柱形的中空本体的壁继续，在其末端处格栅垂直于圆柱体轴线布置。本发明还涉及在根据本发明的用于将组织部分与脑材料分离的方法和包含一种或多种装置的试剂盒中的用途的用途。

9. 发明申请

US20070148035A1 Process for DNA decontamination 审中-公开
标题翻译： DNA去污工艺
公开(公告)号：US20070148035A1
公开(公告)日：2007-06-28
申请号：US11564441
申请日：2006-11-29
申请人： Armin Tgetgel , Joachim Siedel , Alois Rainer , Wolf-Dieter Engel
发明人： Armin Tgetgel , Joachim Siedel , Alois Rainer , Wolf-Dieter Engel
IPC分类号： C12M1/34 , A61L2/20
CPC分类号： A61L2/206
摘要： A method and a disposable to avoid false nucleic acid amplification results based on the alklylation of DNA present at surfaces of disposables. More particularly, the present invention is directed to an improved method and a disposable, whereby the alkylation of DNA is performed using ethylene oxide.
摘要翻译：基于存在于一次性物品表面的DNA的烷基化反应的方法和一次性以避免假核酸扩增结果。更具体地说，本发明涉及一种改进的方法和一次性物质，由此使用环氧乙烷进行DNA的烷基化。

10. 发明申请

US20100124779A1 Two-Step Moulded Capillary 审中-公开
标题翻译：两步成型毛细管
公开(公告)号：US20100124779A1
公开(公告)日：2010-05-20
申请号：US12616822
申请日：2009-11-12
申请人： Alois Rainer , Andre Stutz
发明人： Alois Rainer , Andre Stutz
IPC分类号： C12M1/00 , B29C45/22 , B29C45/13
CPC分类号： B01L3/5082 , B01L3/508 , B01L7/52 , B01L2200/12 , B01L2300/12 , B29C45/16
摘要： Reaction containers, such as plastic capillaries having an optimized volume-to-surface ratio that are suitable for real-time nucleic acid amplification (rtPCR) applications are disclosed as well as a method for the production of the reaction containers, in particularly the trtPCR plastic capillaries via a 2-step molding process. In the process, a capillary section is closed at one end, a tubular section is provided opened at both ends, and a linkage is provided between the capillary section and the tubular section, wherein the linkage is a fused joint designed to permanently link the open end of the capillary section to one of the open ends of the tubular section thus forming a reaction container having one opening, and in which the fused joint produces light scatter upon illumination.
摘要翻译：公开了具有适于实时核酸扩增（rtPCR）应用的具有优化的体积对表面比的塑料毛细管的反应容器以及用于生产反应容器的方法，特别是trtPCR塑料毛细管通过两步成型过程。在该过程中，毛细管部分在一端封闭，管状部分设置在两端开口，并且在毛细管部分和管状部分之间设置有连杆，其中连杆是设计成永久连接开口从而形成具有一个开口的反应容器，并且熔融接头在照射时产生光散射。

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