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1. 发明申请

US20060001683A1 Structure image generation 审中-公开
标题翻译：结构图像生成
公开(公告)号：US20060001683A1
公开(公告)日：2006-01-05
申请号：US11087423
申请日：2005-03-23
申请人： Alexander May , Jason Goldstein
发明人： Alexander May , Jason Goldstein
IPC分类号： G09G5/00
CPC分类号： H04L67/125 , H04L12/2816 , H04L67/12
摘要： Methods and apparatus, including computer program products, for structure image generation. A network includes a corporate server linked to a building server, devices linked to the building server, a first set of the devices selectively controlling room light emanating to an exterior of a structure from a plurality of rooms within the structure, and a second set of devices selectively controlling lighting fixtures within the plurality of rooms, the first set of devices integrated with the second set of devices.
摘要翻译：方法和设备，包括计算机程序产品，用于结构图像生成。网络包括链接到建筑物服务器的公司服务器，连接到建筑服务器的设备，第一组设备选择性地控制从结构内的多个房间发出到结构的外部的房间光，以及第二组选择性地控制多个房间内的照明设备的设备，与第二组设备集成的第一组设备。

2. 发明授权

US09428437B2 Method for dehydrating alpha-substituted carboxylic acids 有权
标题翻译：脱水α-取代羧酸的方法
公开(公告)号：US09428437B2
公开(公告)日：2016-08-30
申请号：US14891861
申请日：2014-04-28
申请人： Alexander May , Steffen Krill , Joerg Becker , Willi Ploesser , Marcel Treskow , Martin Koestner
发明人： Alexander May , Steffen Krill , Joerg Becker , Willi Ploesser , Marcel Treskow , Martin Koestner
IPC分类号： C07C51/44 , C07C51/47 , C07C51/48 , C07C51/377 , C07C51/43
CPC分类号： C07C51/377 , C07C51/43 , C07C51/44 , C07C51/47 , C07C51/48 , Y02P20/582 , C07C57/04
摘要： The present invention describes a process for preparing alpha-beta-unsaturated carboxylic acids by dehydration of hydroxycarboxylic or alkoxycarboxylic acids which are substituted in the alpha position, in particular 2-hydroxyisobutyric acid, while avoiding accumulation of by-products and additives.
摘要翻译：本发明描述了通过在α位被取代的羟基羧酸或烷氧基羧酸脱水制备α-β-不饱和羧酸的方法，特别是2-羟基异丁酸，同时避免了副产物和添加剂的积累。

3. 发明授权

US07999130B2 Methods for producing alkyl(meth)acrylates 有权
标题翻译：（甲基）丙烯酸烷基酯的制备方法
公开(公告)号：US07999130B2
公开(公告)日：2011-08-16
申请号：US11915042
申请日：2006-05-12
申请人： Jochen Ackermann , Alexander May , Udo Gropp , Hermann Siegert , Bernd Vogel , Soenke Broecker
发明人： Jochen Ackermann , Alexander May , Udo Gropp , Hermann Siegert , Bernd Vogel , Soenke Broecker
IPC分类号： C07C67/02
CPC分类号： C07C51/09 , C07C51/377 , C07C67/10 , C07C67/327 , C07C59/01 , C07C57/04 , C07C69/54
摘要： The present invention relates to processes for preparing alkyl (meth)acrylates, comprising the steps of transesterifying an alkyl α-hydroxycarboxylate with (meth)acrylic acid to obtain alkyl (meth)acrylates and α-hydroxycarboxylic acid, and dehydrating the α-hydroxycarboxylic acid to obtain (meth)acrylic acid.
摘要翻译：本发明涉及制备（甲基）丙烯酸烷基酯的方法，包括以下步骤：将α-羟基羧酸烷基酯与（甲基）丙烯酸酯交换得到（甲基）丙烯酸烷基酯和α-羟基羧酸，并将α-羟基羧酸得到（甲基）丙烯酸。

4. 发明申请

US20110034728A1 CATALYST FOR REACTING CARBOXYLIC ACID NITRILES 有权
标题翻译：用于反应羧酸硝酸酯的催化剂
公开(公告)号：US20110034728A1
公开(公告)日：2011-02-10
申请号：US12937659
申请日：2009-02-26
申请人： Alexander May , Bernd Vogel , Hermann Siegert , Kurt-Alfred Gaudschun , Thomas Quandt
发明人： Alexander May , Bernd Vogel , Hermann Siegert , Kurt-Alfred Gaudschun , Thomas Quandt
IPC分类号： C07C231/00 , B01J23/34 , B01J21/08 , B01J21/16
CPC分类号： B01J23/34 , B01J35/002 , B01J37/0009 , B01J37/0063 , C07C231/065 , C07C235/06
摘要： The present invention relates to a catalyst for reacting carbonitriles with water, wherein the catalyst comprises at least 60% by weight of manganese dioxide with an empirical formula MnOx where x is in the range from 1.7 to 2.0, and at least one plasticizer.The present invention further relates to a process for preparing the catalysts detailed above and to a process for preparing carboxamides by reacting carbonitriles with water in the presence of the present catalyst.
摘要翻译：本发明涉及一种用于使碳腈与水反应的催化剂，其中催化剂包含至少60重量％的经验式MnO x，其中x在1.7至2.0范围内的二氧化锰和至少一种增塑剂。本发明还涉及上述详细描述的催化剂的制备方法，以及在本催化剂存在下使碳腈与水反应制备羧酰胺的方法。

5. 发明申请

US20210228668A1 MICROVESICLES DERIVED FROM FERMENTED PLANT-BASED PRODUCTS, METHOD FOR THEIR PREPARATION AND USE 有权
公开(公告)号：US20210228668A1
公开(公告)日：2021-07-29
申请号：US15734019
申请日：2019-06-03
申请人： Alexander May , Kordula Niedermaier-May
发明人： Alexander May
IPC分类号： A61K36/48 , A61K36/52 , A61K36/60 , A61K36/752 , A61K36/889 , A61K36/8962 , A61K36/23 , A61K36/28 , A61K36/899 , C12P1/04 , A23L33/105 , A23L33/135 , A23L33/00
摘要： Provided are extracellular vesicles prepared from fermentation products of natural raw materials as well as methods for their production and enrichment. The extracellular vesicles are characterized by a unique size distribution and are particularly suitable for use in health-promoting products, food supplements and drugs.

6. 发明授权

US08975440B2 Method for producing a carboxylic acid amide from a carbonyl compound and hydrocyanic acid 有权
标题翻译：由羰基化合物和氢氰酸制备羧酸酰胺的方法
公开(公告)号：US08975440B2
公开(公告)日：2015-03-10
申请号：US13131462
申请日：2009-10-29
申请人： Alexander May , Martin Koestner , Joerg Becker , Joerg Schallenberg , Hermann Siegert , Bernd Vogel
发明人： Alexander May , Martin Koestner , Joerg Becker , Joerg Schallenberg , Hermann Siegert , Bernd Vogel
IPC分类号： C07C231/06 , C07C253/30 , C07C67/327 , C07C253/06 , C07C255/13 , C07C69/54 , C07C231/14 , C07C253/00
CPC分类号： C07C231/06 , C07C231/065 , C07C231/14 , C07C253/00 , C07C233/09 , C07C255/16
摘要： The invention relates to a method for producing a carboxylic acid amide from a carbonyl compound and hydrocyanic acid, comprising the steps of A) reacting a carbonyl compound with hydrocyanic acid to produce a hydroxycarboxylic acid nitrile, B) hydrolysis of the hydroxycarboxylic acid nitrile obtained in step A) in the presence of a catalyst comprising manganese dioxide, wherein a molar excess of carbonyl compound is used in relation to the hydrocyanic acid to react the carbonyl compound with hydrocyanic acid according to step A), and the reaction mixture obtained in step A) is not purified by distillation before the hydrolysis according to step B) is carried out. The invention furthermore relates to a method for producing alkyl(meth)acrylates from polymers, moulding compounds and moulded bodies, wherein a method for producing a carboxylic acid amide from a carbonyl compound and hydrocyanic acid is carried out in accordance with the method described above.
摘要翻译：本发明涉及一种由羰基化合物和氢氰酸制备羧酸酰胺的方法，包括以下步骤：a）使羰基化合物与氢氰酸反应生成羟基羧酸腈，B）水解得到的羟基羧酸腈步骤A）在包含二氧化锰的催化剂存在下，其中相对于氢氰酸使用摩尔过量的羰基化合物以使羰基化合物与氢氰酸根据步骤A）反应，并将步骤A中获得的反应混合物）在根据步骤B）进行水解之前未经蒸馏纯化。本发明还涉及从聚合物，成型化合物和成型体制备（甲基）丙烯酸烷基酯的方法，其中根据上述方法由羰基化合物和氢氰酸制备羧酸酰胺的方法。

7. 发明申请

US20140135521A1 METHOD FOR PRODUCING ALPHA-HYDROXYCARBOXYLIC ACID ESTERS 审中-公开
标题翻译：生产α-羟基羧基酸酯的方法
公开(公告)号：US20140135521A1
公开(公告)日：2014-05-15
申请号：US14129811
申请日：2012-07-03
申请人： Martin Koestner , Willi Ploesser , Alexander May
发明人： Martin Koestner , Willi Ploesser , Alexander May
IPC分类号： C07C51/06
CPC分类号： C07C51/06 , C07C67/20 , C07C69/675
摘要： The present invention relates to a continuous process for preparing alpha-hydroxycarboxylic esters by reacting at least one alpha-hydroxycarboxamide present in the liquid phase with an alcohol in the presence of a catalyst, which is characterized in that the resulting alpha-hydroxycarboxylic ester is at least partly separated from the reaction mixture via the gas phase.
摘要翻译：本发明涉及通过使存在于液相中的至少一种α-羟基羧酰胺与醇在催化剂存在下反应来制备α-羟基羧酸酯的方法，其特征在于所得的α-羟基羧酸酯在通过气相至少部分地与反应混合物分离。

8. 发明授权

US08334406B2 Process for preparing carboxamides by hydrolysis carboxylic acid nitriles in the presence of a catalyst comprising manganese dioxide 有权
标题翻译：在含有二氧化锰的催化剂存在下，通过羧酸腈水解制备羧酰胺的方法
公开(公告)号：US08334406B2
公开(公告)日：2012-12-18
申请号：US12515036
申请日：2007-08-30
申请人： Alexander May , Jochen Ackermann , Hermann Siegert , Bernd Vogel , Soenke Broecker
发明人： Alexander May , Jochen Ackermann , Hermann Siegert , Bernd Vogel , Soenke Broecker
IPC分类号： C07C231/00 , C07C67/20 , C07C67/22
CPC分类号： C07C67/10 , B01J23/34 , C07C51/09 , C07C51/377 , C07C67/20 , C07C231/065 , C07C59/01 , C07C59/08 , C07C57/04 , C07C69/54 , C07C69/68 , C07C235/06
摘要： The present invention relates to a process for preparing carboxamides by hydrolysing carbonitriles in the presence of a catalyst comprising manganese dioxide, wherein the reaction mixture added to the catalyst comprising manganese dioxide has a pH in the range of 6.0 to 11.0 and the hydrolysis is performed in the presence of an oxidizing agent. The present invention further relates to a process for preparing alkyl (meth)acrylates, the process having a hydrolysis step according to the process described above.
摘要翻译：本发明涉及通过在包含二氧化锰的催化剂存在下水解碳腈制备羧酰胺的方法，其中加入到包含二氧化锰的催化剂中的反应混合物的pH在6.0至11.0的范围内，水解在氧化剂的存在。本发明还涉及一种制备（甲基）丙烯酸烷基酯的方法，该方法具有根据上述方法的水解步骤。

9. 发明申请

US20100291644A1 PROCESS FOR PREPARING METHACRYLIC ACID OR METHACRYLIC ESTERS 有权
标题翻译：制备甲基丙烯酸或甲基丙烯酸酯的方法
公开(公告)号：US20100291644A1
公开(公告)日：2010-11-18
申请号：US12602593
申请日：2008-05-30
申请人： Achim Marx , Markus Poetter , Stefan Buchholz , Alexander May , Hermann Siegert , Birgit Alber , Georg Fuchs , Lothar Eggeling
发明人： Achim Marx , Markus Poetter , Stefan Buchholz , Alexander May , Hermann Siegert , Birgit Alber , Georg Fuchs , Lothar Eggeling
IPC分类号： C12P7/62 , C12P7/40 , C12P7/44
CPC分类号： C12P7/42 , C08F120/06 , C08F120/10 , C12N9/0008 , C12N9/001 , C12N9/1096 , C12N9/16 , C12N9/88 , C12P7/40 , C12P7/52 , C12P7/625 , C12Y102/04004 , C12Y103/99012 , C12Y206/01042 , C12Y301/02004 , C12Y402/01017
摘要： The present invention relates to a process for the preparation of methacrylic acid or methacrylic esters, comprising the process steps of IA) preparation of 3-hydroxyisobutyric acid by a process comprising the process step of bringing a cell which has been genetically modified in comparison with its wild type in such a way that it is capable of forming more 3-hydroxyisobutyric acid, or polyhydroxyalkanoates based on 3-hydroxyisobutyric acid in comparison with its wild type, into contact with a nutrient medium comprising, as carbon source, carbohydrates, glycerol, carbon dioxide, methanol, L-valine or L-glutamate under conditions under which 3-hydroxyisobutyric acid or polyhydroxyalkanoates based on 3-hydroxyisobutyric acid are formed from the carbon source, if appropriate, isolation of the 3-hydroxyisobutyric acid from the nutrient medium and also, if appropriate, neutralization of the 3-hydroxyisobutyric acid, IB) dehydration of the 3-hydroxyisobutyric acid with formation of methacrylic acid and also, where appropriate, esterification methacrylic acid. The invention also relates to a process for the preparation of polymethacrylic acid or polymethacrylic esters.
摘要翻译：本发明涉及一种制备甲基丙烯酸或甲基丙烯酸酯的方法，其包括以下工艺步骤：IA）通过包括以下步骤的方法制备3-羟基异丁酸，所述方法包括将经遗传修饰的细胞与其野生型，使得其能够形成更多的3-羟基异丁酸或与其野生型相比基于3-羟基异丁酸的聚羟基链烷酸酯与营养培养基接触，所述营养培养基包含作为碳源的碳水化合物，甘油，碳二氧化物，甲醇，L-缬氨酸或L-谷氨酸盐，其中3-羟基异丁酸或基于3-羟基异丁酸的聚羟基链烷酸酯由碳源形成的条件下，如果合适，则从营养培养基中分离出3-羟基异丁酸，如果适当，中和3-羟基异丁酸，IB）3-羟基异丁酸脱水形成甲基丙烯酸酸，并且在适当的情况下酯化甲基丙烯酸。本发明还涉及一种制备聚甲基丙烯酸或聚甲基丙烯酸酯的方法。

10. 发明申请

US20090209781A1 PROCESS FOR PREPARING ALPHA-HYDROXYCARBOXYLIC ACIDS 审中-公开
标题翻译：制备α-羟基羧酸的方法
公开(公告)号：US20090209781A1
公开(公告)日：2009-08-20
申请号：US12307773
申请日：2007-05-25
申请人： Jochen Ackermann , Alexander May , Udo Gropp , Hermann Siegert , Bernd Vogel , Sönke Bröcker
发明人： Jochen Ackermann , Alexander May , Udo Gropp , Hermann Siegert , Bernd Vogel , Sönke Bröcker
IPC分类号： C07C67/20
CPC分类号： C07C67/20 , C07C67/54 , C07C69/675
摘要： Continuous process for preparing alpha-hydroxycarboxylic esters, in which the reactants reacted are alpha-hydroxycarboxamide with an alcohol in the presence of a catalyst to obtain a product mixture which comprises alpha-hydroxycarboxylic ester, ammonia, unconverted alpha-hydroxycarboxamide and alcohol, and catalyst; wherein a′) reactant streams comprising, as reactants, an alpha-hydroxycarboxamide, an alcohol and a catalyst are fed into a pressure reactor; b′) the reactant streams are reacted with one another in the pressure reactor at a pressure in the range of 1 bar to 100 bar; c′) the product mixture which results from step b) and comprises alpha-hydroxycarboxylic ester, unconverted alpha-hydroxycarboxamide and catalyst, and also ammonia and alcohol, is discharged from the pressure reactor; and d′) the product mixture is depleted in alcohol and ammonia by distilling off ammonia at a pressure which is constantly kept greater than 1 bar without the aid of additional stripping media. The continuous process can be employed particularly advantageously on the industrial scale.
摘要翻译：制备α-羟基羧酸酯的连续方法，其中反应物在催化剂存在下与醇反应为α-羟基甲酰胺，得到包含α-羟基羧酸酯，氨，未转化的α-羟基甲酰胺和醇的产物混合物，以及催化剂 ; 其中包含作为反应物的α-羟基甲酰胺，醇和催化剂的'）反应物料流进入压力反应器; b'），反应物流在压力反应器中在1巴至100巴范围内的压力下彼此反应; c'）由步骤b）得到的包含α-羟基羧酸酯，未转化的α-羟基甲酰胺和催化剂以及氨和醇的产物混合物从压力反应器中排出; 和d'），产物混合物通过在不经额外的汽提介质的帮助下恒定地保持大于1巴的压力下蒸馏出氨而蒸出醇和氨。该连续方法可以在工业规模上特别有利地使用。

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