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1. 发明申请

US20060271032A1 Ablation instruments and methods for performing abalation 审中-公开
标题翻译：消融仪器和方法进行衰减
公开(公告)号：US20060271032A1
公开(公告)日：2006-11-30
申请号：US11137987
申请日：2005-05-26
申请人： Albert Chin , Peter Callas , Shuji Uemura , Geoffrey Willis
发明人： Albert Chin , Peter Callas , Shuji Uemura , Geoffrey Willis
IPC分类号： A61B18/14
CPC分类号： A61B18/1482 , A61B2018/0022 , A61B2018/00351 , A61B2018/00375
摘要： Methods, devices and instruments provided for performing ablation transmurally across the wall of an organ. Devices may directly access tissue to be ablated through direct access openings formed in the patient and, optionally, an organ where the ablation is to be performed. Instruments facilitating making openings, dissecting, and delivery of ablation instruments are also described.
摘要翻译：提供用于跨器官壁穿透消融的方法，装置和仪器。装置可以直接通过形成在患者中的直接进入开口和任选地进行消融的器官进入烧蚀组织。还描述了促进消融器械的开口，解剖和输送的仪器。

2. 发明申请

US20060270900A1 Apparatus and methods for performing ablation 审中-公开
标题翻译：用于进行消融的装置和方法
公开(公告)号：US20060270900A1
公开(公告)日：2006-11-30
申请号：US11138950
申请日：2005-05-26
申请人： Albert Chin , Geoffrey Willis , Shuji Uemura , Alfredo Cantu , Manuel Javier , Theodore Johnson , Amit Agarwal
发明人： Albert Chin , Geoffrey Willis , Shuji Uemura , Alfredo Cantu , Manuel Javier , Theodore Johnson , Amit Agarwal
IPC分类号： A61B1/00 , A61B18/18 , A61M29/00
CPC分类号： A61B1/313 , A61B1/00096 , A61B1/00101 , A61B18/18 , A61B2017/00243
摘要： Apparatus and methods for performing endoscopic surgical procedures where only a minimal number of (or even one) openings are required to perform the procedures. Ablation procedures, including epicardial ablation procedures and apparatus for performing such procedures. Epicardial atrial ablation may be performed epicardially with access through only one side of a patient's chest required to perform all procedures.
摘要翻译：用于执行内窥镜外科手术的装置和方法，其中只需要最少数量（或甚至一个）开口来执行手术。消融手术，包括心外膜消融手术和执行此类手术的装置。心外膜心房消融可以进行心外膜，仅通过患者胸部的一侧进行，以执行所有手术。

3. 发明申请

US20060270909A1 Surgical instruments and methods for use in reduced-access surgical sites 审中-公开
标题翻译：用于减少手术部位的手术器械和方法
公开(公告)号：US20060270909A1
公开(公告)日：2006-11-30
申请号：US11137255
申请日：2005-05-25
申请人： John Davis , Geoffrey Willis , Eric Willis , Charles Gresl , Peter Callas , Thomas Vassiliades
发明人： John Davis , Geoffrey Willis , Eric Willis , Charles Gresl , Peter Callas , Thomas Vassiliades
IPC分类号： A61B1/32
CPC分类号： A61B17/0218 , A61B90/50 , A61B90/57 , A61B2017/0243 , A61B2017/306
摘要： Devices and methods for stabilizing a portion of an organ or tissue in a closed or restricted space surgical site. Devices and methods for manipulating an organ or tissue in a closed or restricted space surgical site. Devices and methods for positioning and orienting stabilizers and manipulators I a closed or restricted space surgical site.
摘要翻译：用于稳定封闭或受限空间手术部位的器官或组织的一部分的装置和方法。用于操纵封闭或受限空间外科手术部位的器官或组织的装置和方法。用于定位和定向稳定器和操纵器的装置和方法I是封闭或受限的空间外科手术部位。

4. 发明申请

US20060217706A1 Tissue welding and cutting apparatus and method 有权
标题翻译：组织焊接和切割设备及方法
公开(公告)号：US20060217706A1
公开(公告)日：2006-09-28
申请号：US11090750
申请日：2005-03-25
申请人： Liming Lau , Arnold Escano , Jerry Jarrard , Sam Ho , Ryan Abbott , Arthur Lin , Jesse McQuiston , Peter Callas , Geoffrey Willis , Michael Stewart , Kimberly Barkman , Joseph Lamberti , Kenny Dang
发明人： Liming Lau , Arnold Escano , Jerry Jarrard , Sam Ho , Ryan Abbott , Arthur Lin , Jesse McQuiston , Peter Callas , Geoffrey Willis , Michael Stewart , Kimberly Barkman , Joseph Lamberti , Kenny Dang
IPC分类号： A61B18/18
CPC分类号： A61B18/085 , A61B17/29 , A61B18/1445 , A61B90/03 , A61B2017/00084 , A61B2017/00353 , A61B2017/00504 , A61B2017/2912 , A61B2017/2936 , A61B2017/2945 , A61B2017/3445 , A61B2018/1432
摘要： A surgical apparatus and methods for severing and welding tissue, in particular blood vessels. The apparatus includes an elongated shaft having a pair of relatively movable jaws at a distal end thereof. A first heating element on one of the jaws is adapted to heat up to a first temperature and form a welded region within the tissue, while a second heating element on one of the jaws is adapted to heat up to a second temperature and sever the tissue within the welded region. The first and second heating elements may be provided on the same or opposite jaws. A control handle provided on the proximal end of the elongated shaft includes controls for opening and closing the jaws, and may include an actuator for sending current through the first and second heating elements. The first and second heating elements may be electrically connected in series, and the first heating element may be bifurcated such that it conducts about one half of the current as the second heating element. A force-limiting mechanism provided either within the control handle, in the elongated shaft, or at the jaws limits the pressure applied to the tissue by the jaws to ensure that the tissue is severed and the ends effectively welded within a short amount of time.
摘要翻译：用于切断和焊接组织，特别是血管的手术设备和方法。该装置包括细长轴，其在其远端具有一对相对可动的钳口。其中一个钳口上的第一加热元件适于加热至第一温度并在组织内形成焊接区域，而其中一个钳口上的第二加热元件适于加热至第二温度并切断组织在焊接区域内。第一和第二加热元件可以设置在相同或相对的夹爪上。设置在细长轴的近端的控制手柄包括用于打开和关闭钳口的控制器，并且可以包括用于通过第一和第二加热元件发送电流的致动器。第一和第二加热元件可以串联电连接，并且第一加热元件可以分叉，使得其作为第二加热元件传导大约电流的一半。设置在控制手柄，细长轴或钳口内的力限制机构限制由钳口施加到组织上的压力，以确保组织被切断并且端部在短时间内有效地焊接。

5. 发明申请

US20060079915A1 Temporary anastomotic seal and method 失效
标题翻译：临时吻合口腔和方法
公开(公告)号：US20060079915A1
公开(公告)日：2006-04-13
申请号：US10123470
申请日：2002-04-15
申请人： Albert Chin , Dwight Morejohn , Charles Taylor , Steven Choi , Eugene Reis , John Davis , Geoffrey Willis , Edward Pineda , Kushal Vepa
发明人： Albert Chin , Dwight Morejohn , Charles Taylor , Steven Choi , Eugene Reis , John Davis , Geoffrey Willis , Edward Pineda , Kushal Vepa
IPC分类号： A61B17/08
CPC分类号： A61B17/0057 , A61B17/12022 , A61B17/12027 , A61B17/12031 , A61B17/12036 , A61B17/1204 , A61B17/12045 , A61B17/32053 , A61B2017/00362 , A61B2017/00575 , A61B2017/0061 , A61B2017/00632 , A61B2017/00637 , A61B2017/00641 , A61B2017/00659 , A61B2017/1107
摘要： Forming a proximal anastomosis on an aortic wall includes method and instrumentation and apparatus for forming an aortic puncture and inserting into the vessel through the puncture a fluid-impervious sealing element with a protruding retainer. An anastomosis of a graft vessel over the puncture is partially completed with the retainer of the sealing element protruding through the partial anastomosis. The retainer facilitates removal of the sealing element from the partial anastomosis prior to completion of the procedure.
摘要翻译：在主动脉壁上形成近端吻合包括用于形成主动脉穿刺的方法和仪器和装置，并且通过穿刺插入具有突出保持器的不透液体的密封元件的容器中。通过部分吻合突出的密封元件的保持器部分地完成了在穿刺上的移植血管的吻合。保持器有助于在完成手术之前从部分吻合中去除密封元件。

6. 发明申请

US20070167964A1 Tubular anastomosis ring having alternating flexible and rigid sections 审中-公开
标题翻译：管状吻合环具有交替的柔性和刚性部分
公开(公告)号：US20070167964A1
公开(公告)日：2007-07-19
申请号：US11726567
申请日：2007-03-21
申请人： Geoffrey Willis
发明人： Geoffrey Willis
IPC分类号： A61B17/08
CPC分类号： A61B17/115 , A61B2017/1107 , A61B2017/1135
摘要： A ring for use in preparing a first organ for anastomosis with a second organ, wherein the first organ has an orifice, and the ring has a central ring portion sized to extend around the orifice and malleable tines that extend from the ring portion. The ring portion is configured to dilate and contract radially relative to the central axis. Malleable tines may extend out from the ring portion. The tubular shape of the ring provides rigidity parallel to the central axis thereof and flexibility in directions perpendicular to the central axis. In another class of embodiments, the central ring portion is a tubular member, which is preferably but not necessarily capable of dilating and contracting radially relative to the central axis. In some embodiments, the central ring portion includes rigid sections alternating with bowed sections, each of the bowed sections functioning as a spring capable of flexing to allow the rigid sections adjacent thereto to move radially inward and outward. In other embodiments, the central ring portion includes rigid sections, which can be made of metal, alternating with elastic sections, which can be made of elastomeric material such as silicone rubber or superelastic material or memory metal. Installation tools are also provided.
摘要翻译：一种用于制备用于与第二器官吻合的第一器官的环，其中所述第一器官具有孔口，并且所述环具有尺寸设置成围绕所述孔延伸的中心环部分和从所述环部分延伸的可延展的齿。环部分构造成相对于中心轴径向膨胀和收缩。可延展的齿可以从环部分延伸出来。环的管状提供了平行于其中心轴线的刚性和垂直于中心轴线的方向的柔性。在另一类实施例中，中心环部分是管状构件，其优选地但不一定能够相对于中心轴径向膨胀和收缩。在一些实施例中，中心环部分包括与弓形部分交替的刚性部分，每个弯曲部分用作弹簧，弹簧能够弯曲以允许与其相邻的刚性部分径向向内和向外移动。在其它实施例中，中心环部分包括刚性部分，其可由金属制成，与弹性部分交替，弹性部分可以由诸如硅橡胶或超弹性材料或记忆金属的弹性体材料制成。还提供安装工具。

7. 发明授权

US07931590B2 Tissue stabilizer and methods of using the same 有权
标题翻译：组织稳定剂及其使用方法
公开(公告)号：US07931590B2
公开(公告)日：2011-04-26
申请号：US10283784
申请日：2002-10-29
申请人： Geoffrey Willis
发明人： Geoffrey Willis
IPC分类号： A61B1/32
CPC分类号： A61B17/0218 , A61B2017/00243 , A61B2017/0243
摘要： Devices and methods are provided for stabilizing tissue, e.g., a beating heart, within a patient's body. In certain embodiments, the subject devices are characterized by having a shaft and at least two contacting members operatively associated with the shaft where the contacting members are capable of assuming a substantial coaxial alignment when in a low profile configuration and also capable of assuming an open, working configuration. In other embodiments, the devices are characterized by having a shaft and at least one tissue contacting member associated with the shaft using a ball and socket mechanism, wherein the at least one tissue contacting member may be caused to pitch and/or roll and/or yaw. In the subject methods, a subject device is advanced to the target site and stabilizes the target tissue using compression, negative pressure or both. The subject invention also includes kits for use in practicing the subject methods.
摘要翻译：提供了用于在患者体内稳定组织，例如跳动心脏的装置和方法。在某些实施例中，本发明装置的特征在于具有轴和至少两个与轴可操作地相关联的接触构件，其中当处于低轮廓构造时，接触构件能够基本上同轴对准，并且还能够承受开放，工作配置。在其它实施例中，装置的特征在于具有轴和使用球窝机构与轴相关联的至少一个组织接触构件，其中可以使至少一个组织接触构件俯仰和/或滚动和/或偏航。在本发明方法中，将目标装置推进到目标部位，并使用压缩，负压或两者稳定目标组织。本发明还包括用于实践本发明方法的试剂盒。

8. 发明申请

US20060293740A1 Epicardial lead fixation system 审中-公开
标题翻译：心外膜固定系统
公开(公告)号：US20060293740A1
公开(公告)日：2006-12-28
申请号：US11168048
申请日：2005-06-28
申请人： Ronald Heil , Geoffrey Willis
发明人： Ronald Heil , Geoffrey Willis
IPC分类号： A61N1/00
CPC分类号： A61N1/0587
摘要： A cardiac pacing lead for electrically communicating with a human heart is attached to the heart using an adhesive. The lead includes a flexible, elongated lead body having a proximal end and a distal end, a pad having an interface surface coupled to the lead body at the distal end. An electrode is coupled to the pad. The lead further includes an adhesive for bonding the pad to the heart such that the electrode is electrically coupled to the heart. The adhesive is delivered to the interface surface after the lead has been inserted into a subject. In one embodiment, the lead system includes an anchor having an interface surface adapted for adhesive coupling to the heart. In this embodiment, the anchor is coupled to a tether and the lead includes a lumen adapted to accept the tether and to allow advancement of the lead over the tether.
摘要翻译：使用粘合剂将与人心脏电连通的心脏起搏引线附接到心脏。引线包括具有近端和远端的柔性细长的引线主体，具有在远端处与引线主体耦合的接口表面的焊盘。电极耦合到焊盘。引线还包括用于将焊盘接合到心脏的粘合剂，使得电极电耦合到心脏。在铅被插入到受试者之后，粘合剂被传送到界面表面。在一个实施例中，引导系统包括具有适于粘附到心脏的界面的锚固件。在该实施例中，锚固件连接到系绳，并且引线包括适于接纳系绳并允许引线前进到系绳的内腔。

9. 发明申请

US20050027308A1 Methods for performing anastomosis 审中-公开
标题翻译：进行吻合的方法
公开(公告)号：US20050027308A1
公开(公告)日：2005-02-03
申请号：US10897523
申请日：2004-07-23
申请人： John Davis , Geoffrey Willis
发明人： John Davis , Geoffrey Willis
IPC分类号： A61B17/064 , A61B17/11 , A61B17/08
CPC分类号： A61B17/0644 , A61B17/11 , A61B2017/00477 , A61B2017/0641 , A61B2017/1107 , A61B2017/1135 , A61B2017/1139
摘要： Methods of performing an anastomosis. A ring is installed at an incision or other orifice in a vessel or other organ, for use in performing an anastomosis. To install the ring, tines are advanced against an anvil to cause them to grab tissue around the orifice and curl radially. The anvil is then retracted to fold the tines so their curled ends move radially outward. A sleeve may be advanced to fold or bend the tines as their curled ends move further radially outward. The folding, curling, and further bending of the tines evert tissue near the orifice edges to expose the vessel's or organs' intima.
摘要翻译：进行吻合的方法将环安装在容器或其他器官中的切口或其他孔口上，用于进行吻合。为了安装环，尖针先进抵靠砧座，使它们抓住孔周围的组织并且径向卷曲。然后将砧座缩回以折叠尖齿，使得它们的卷曲端部径向向外移动。当其卷曲的端部进一步径向向外移动时，套筒可以被推进以折叠或弯曲尖齿。齿的折叠，卷曲和进一步的弯曲使得在孔边缘附近的组织转移以暴露血管或器官的内膜。

10. 发明申请

US20100249946A1 TRANSCUTANEOUSLY ADJUSTABLE FLUID-FILLED IMPLANTS 审中-公开
标题翻译：经过可调节的流体填充的植入物
公开(公告)号：US20100249946A1
公开(公告)日：2010-09-30
申请号：US12412830
申请日：2009-03-27
申请人： Michael D. Lesh , Stewart Kume , Randy J. Kesten , Geoffrey Willis , Leo Centeno , Jeff Christian
发明人： Michael D. Lesh , Stewart Kume , Randy J. Kesten , Geoffrey Willis , Leo Centeno , Jeff Christian
IPC分类号： A61F2/02
CPC分类号： A61F2/0059 , A61F2250/0003
摘要： Disclosed are implantable tissue augmentation devices, methods, and associated tools. The devices include an inflatable body, having a self-sealing membrane operably attached to a wall of the implant. The self-sealing membrane provides access for filling the device, and includes a first layer comprising a fabric. The fabric has a first plurality of yarn strands positioned in a first direction, and a second plurality of yarn strands positioned in a second direction. The first and second plurality of yarn strands intersect to form a matrix pattern with cells defined by free spaces between yarn strands. The membrane also includes a first elastomeric material configured to fill the cells as well as form a coating over the first and second plurality of yarn strand, and a second layer comprising a second elastomeric material. The second elastomeric material has a lower durometer than the first elastomeric material. Kits and systems are also disclosed.
摘要翻译：公开了可植入组织增强装置，方法和相关联的工具。所述装置包括可充气体，其具有可操作地附接到所述植入物的壁的自密封膜。自密封膜提供用于填充装置的通路，并且包括包括织物的第一层。织物具有沿第一方向定位的第一多根纱线和位于第二方向上的第二多根纱线。第一和第二多根纱线相交以形成具有由纱线之间的自由空间限定的细胞的矩阵图案。膜还包括构造成填充细胞并且在第一和第二多根纱线上形成涂层的第一弹性体材料，以及包含第二弹性体材料的第二层。第二弹性体材料具有比第一弹性体材料低的硬度。还披露了套件和系统。

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