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1. 发明申请

WO2006126979A2 SYSTEM AND METHOD FOR DELIVERING A LEFT ATRIAL APPENDAGE CONTAINMENT DEVICE 审中-公开
标题翻译：用于提供左心室附件容纳装置的系统和方法
公开(公告)号：WO2006126979A2
公开(公告)日：2006-11-30
申请号：PCT/US2004040642
申请日：2004-12-03
申请人： EV3 INC , VAN DE BURG ERIK J , STEWART KUME M
发明人： VAN DE BURG ERIK J , STEWART KUME M
IPC分类号： A61B17/00 , A61B17/08 , A61B17/12
CPC分类号： A61F2/01 , A61B17/0057 , A61B17/12022 , A61B17/12122 , A61B17/12172 , A61B2017/003 , A61B2017/00575 , A61B2017/00579 , A61B2017/00592 , A61B2017/00597 , A61B2017/00615 , A61B2017/00623 , A61B2017/00632 , A61B2017/12054 , A61B2017/12095 , A61F2/013 , A61F2002/018 , A61F2230/0006 , A61F2230/0071 , A61F2230/008
摘要： A method of delivering and deploying the device for containing the emboli during a surgical procedure proximate to the heart. Access is gained to the heart and the left atrium such that a distal end of the delivery sheath can be located near the left atrial appendage. A distal end of a delivery catheter can be loaded with the device in a collapsed position and passed through the delivery sheath thereby delivering the device within the left atrial appendage. The device is expanded to contain emboli in the left atrium appendage.
摘要翻译：在靠近心脏的外科手术过程中递送和展开用于容纳栓塞的装置的方法。获得进入心脏和左心房，使得输送鞘的远端可以位于左心耳附近。输送导管的远端可以装载在折叠位置并且穿过输送护套，从而将装置输送到左心耳内。该装置扩展为在左心房附属物中含有栓塞。

2. 发明申请

WO2006126979A3 SYSTEM AND METHOD FOR DELIVERING A LEFT ATRIAL APPENDAGE CONTAINMENT DEVICE 审中-公开
公开(公告)号：WO2006126979A3
公开(公告)日：2006-11-30
申请号：PCT/US2004/040642
申请日：2004-12-03
申请人： EV3, INC. , VAN DE BURG, Erik, J. , STEWART, Kume, M.
发明人： VAN DE BURG, Erik, J. , STEWART, Kume, M.
IPC分类号： A61F2/01
摘要： A method of delivering and deploying the device for containing the emboli during a surgical procedure proximate to the heart. Access is gained to the heart and the left atrium such that a distal end of the delivery sheath can be located near the left atrial appendage. A distal end of a delivery catheter can be loaded with the device in a collapsed position and passed through the delivery sheath thereby delivering the device within the left atrial appendage. The device is expanded to contain emboli in the left atrium appendage.

3. 发明申请

US20120209273A1 TISSUE REMOVAL SYSTEM WITH RETENTION MECHANISM 有权
标题翻译：组织拆卸系统与保持机制
公开(公告)号：US20120209273A1
公开(公告)日：2012-08-16
申请号：US13297260
申请日：2011-11-15
申请人： Gary D. Zaretzka , Myra I. L. Fabro , Stewart Kume , John To
发明人： Gary D. Zaretzka , Myra I. L. Fabro , Stewart Kume , John To
IPC分类号： A61B17/16
CPC分类号： A61B17/32002 , A61B17/320725 , A61B17/320783 , A61B2017/00261 , A61B2017/00398 , A61B2017/22038 , A61B2017/22079 , A61B2017/320733 , A61B2017/320775
摘要： Systems and methods for minimally invasive discectomy procedures are described herein. In some variations, a tissue removal system may comprise a handheld housing, an outer shaft comprising a distal portion and a proximal portion coupled to the handheld housing, a distal sheath coupled to the distal portion of the outer shaft, a motor, an inner shaft coupled to the motor, where the inner shaft is located partially within the outer shaft and partially within the distal sheath, a tip portion coupled to a distal portion of the inner shaft, and an elongate member distally extending through a distal opening of the inner shaft, the elongate member having a retracted configuration and an extended configuration, where the distal sheath comprises at least one element (e.g. at least one protrusion) that engages the tip portion to couple the tip portion to the distal sheath.
摘要翻译：本文描述了用于微创椎间盘切除术的系统和方法。在一些变型中，组织去除系统可以包括手持式外壳，外轴包括远端部分和联接到手持式外壳的近端部分，与外轴的远端部分联接的远端护套，电动机，内轴耦合到所述电动机，其中所述内轴部分地位于所述外轴内部并且部分地位于所述远侧护套内，与所述内轴的远端部分联接的末端部分和远离所述内轴的远端开口的细长构件所述细长构件具有缩回构型和延伸构型，其中所述远侧护套包括接合所述尖端部分以将所述尖端部分连接到所述远侧护套的至少一个元件（例如至少一个突出部）。

4. 发明申请

US20100249947A1 POROUS IMPLANT WITH EFFECTIVE EXTENSIBILITY AND METHODS OF FORMING AN IMPLANT 审中-公开
标题翻译：具有有效扩展性的多孔植入物和形成植入物的方法
公开(公告)号：US20100249947A1
公开(公告)日：2010-09-30
申请号：US12413240
申请日：2009-03-27
申请人： Michael D. Lesh , Stewart Kume , Randy J. Kesten , Leo Centeno , Jeff Zalewski
发明人： Michael D. Lesh , Stewart Kume , Randy J. Kesten , Leo Centeno , Jeff Zalewski
IPC分类号： A61F2/02 , B32B37/00
CPC分类号： B32B37/00 , A61L27/16 , A61L27/56 , A61L31/048 , A61L31/146 , C08L27/18
摘要： The implant includes an outer layer of ePTFE which exhibits extensibility normally not associated with ePTFE. The ePTFE is reduced in length by deforming the fibrils between the nodes while maintaining the nodes in a substantially flat configuration. Various implant configurations that can include the outer layer described are also disclosed.
摘要翻译：植入物包括ePTFE的外层，其表现出通常不与ePTFE相关的延展性。通过使节点之间的原纤维变形，同时将节点保持在基本平坦的构型中，ePTFE的长度减小。还公开了可以包括所描述的外层的各种植入物构造。

5. 发明申请

US20100249946A1 TRANSCUTANEOUSLY ADJUSTABLE FLUID-FILLED IMPLANTS 审中-公开
标题翻译：经过可调节的流体填充的植入物
公开(公告)号：US20100249946A1
公开(公告)日：2010-09-30
申请号：US12412830
申请日：2009-03-27
申请人： Michael D. Lesh , Stewart Kume , Randy J. Kesten , Geoffrey Willis , Leo Centeno , Jeff Christian
发明人： Michael D. Lesh , Stewart Kume , Randy J. Kesten , Geoffrey Willis , Leo Centeno , Jeff Christian
IPC分类号： A61F2/02
CPC分类号： A61F2/0059 , A61F2250/0003
摘要： Disclosed are implantable tissue augmentation devices, methods, and associated tools. The devices include an inflatable body, having a self-sealing membrane operably attached to a wall of the implant. The self-sealing membrane provides access for filling the device, and includes a first layer comprising a fabric. The fabric has a first plurality of yarn strands positioned in a first direction, and a second plurality of yarn strands positioned in a second direction. The first and second plurality of yarn strands intersect to form a matrix pattern with cells defined by free spaces between yarn strands. The membrane also includes a first elastomeric material configured to fill the cells as well as form a coating over the first and second plurality of yarn strand, and a second layer comprising a second elastomeric material. The second elastomeric material has a lower durometer than the first elastomeric material. Kits and systems are also disclosed.
摘要翻译：公开了可植入组织增强装置，方法和相关联的工具。所述装置包括可充气体，其具有可操作地附接到所述植入物的壁的自密封膜。自密封膜提供用于填充装置的通路，并且包括包括织物的第一层。织物具有沿第一方向定位的第一多根纱线和位于第二方向上的第二多根纱线。第一和第二多根纱线相交以形成具有由纱线之间的自由空间限定的细胞的矩阵图案。膜还包括构造成填充细胞并且在第一和第二多根纱线上形成涂层的第一弹性体材料，以及包含第二弹性体材料的第二层。第二弹性体材料具有比第一弹性体材料低的硬度。还披露了套件和系统。

6. 发明申请

US20060206148A1 Method of implanting an adjustable occlusion device 有权
标题翻译：植入可调闭塞装置的方法
公开(公告)号：US20060206148A1
公开(公告)日：2006-09-14
申请号：US11434012
申请日：2006-05-15
申请人： Alexander Khairkhahan , Andrew Frazier , Alan Klenk , Marc Kreidler , Stewart Kume , Darrell Ogi , Chad Roue , Erik van der Burg
发明人： Alexander Khairkhahan , Andrew Frazier , Alan Klenk , Marc Kreidler , Stewart Kume , Darrell Ogi , Chad Roue , Erik van der Burg
IPC分类号： A61B17/08
CPC分类号： A61B17/0057 , A61B17/12022 , A61B17/12122 , A61B17/12172 , A61B17/122 , A61B2017/00243 , A61B2017/00557 , A61B2017/00575 , A61B2017/00579 , A61B2017/00592 , A61B2017/00597 , A61B2017/00615 , A61B2017/00619 , A61B2017/00623 , A61B2017/081 , A61B2017/1205 , A61B2017/12095 , A61F2/01 , A61F2002/011 , A61F2002/018 , A61F2230/0006 , A61F2230/0071 , A61F2230/008 , A61M25/10 , A61M2025/1054 , A61M2210/125
摘要： Disclosed is an adjustable occlusion device for use in a body lumen such as the left atrial appendage. The occlusion device is removably carried by a deployment catheter. The device may be enlarged or reduced to facilitate optimal placement or removal. Methods are also disclosed.
摘要翻译：公开了一种用于体腔内的可调闭塞装置，例如左心耳。闭塞装置可移除地由展开导管携带。该装置可以被放大或缩小，以便于最佳的放置或移除。还公开了方法。

7. 发明申请

US20060058892A1 Valved tissue augmentation implant 审中-公开
标题翻译：瓣膜增生植入物
公开(公告)号：US20060058892A1
公开(公告)日：2006-03-16
申请号：US10942317
申请日：2004-09-16
申请人： Michael Lesh , Stewart Kume
发明人： Michael Lesh , Stewart Kume
IPC分类号： A61F2/10 , A61F2/02
CPC分类号： A61B17/3468 , A61B2017/00747 , A61B2017/00792 , A61F2/0059
摘要： A medical device and methods for filling tissue are disclosed. The device has a first configuration wherein the device can pass through a small catheter or needle placed in the tissue to be filled and a second configuration in which the device is expanded within the tissue to be filled. The exterior profile of the expanded device may be customized along its length, to achieve a desired cosmetic or therapeutic result. In one embodiment, the device comprises an outer sleeve for containing filler and a valve on the sleeve for retaining the filler therein. The device is adapted to be placed through a needle in the skin to reduce facial wrinkles or augment facial features such as the lips.
摘要翻译：公开了用于填充组织的医疗装置和方法。该装置具有第一配置，其中该装置可以通过放置在待填充的组织中的小导管或针和第二构型，其中该装置在待填充的组织内扩张。扩展装置的外部轮廓可以沿其长度定制，以实现期望的化妆品或治疗结果。在一个实施例中，该装置包括用于容纳填充物的外套筒和用于将填料保持在其上的套筒上的阀。该装置适于通过皮肤中的针放置以减少面部皱纹或增加诸如嘴唇的面部特征。

8. 发明申请

US20130023882A1 DISCECTOMY DEVICES AND RELATED METHODS 审中-公开
标题翻译：分离装置及相关方法
公开(公告)号：US20130023882A1
公开(公告)日：2013-01-24
申请号：US13396438
申请日：2012-02-14
申请人： Myra I. L. Fabro , Gary D. Zaretzka , Stewart Kume , John Davis , Sam Boong Park
发明人： Myra I. L. Fabro , Gary D. Zaretzka , Stewart Kume , John Davis , Sam Boong Park
IPC分类号： A61B17/16
CPC分类号： A61B17/32002 , A61B17/1615 , A61B17/162 , A61B17/1622 , A61B17/1633 , A61B17/1671 , A61B17/295 , A61B2017/320024 , A61B2217/005 , A61B2217/007
摘要： A tissue removal device may comprise a handheld housing, a motor, and a tissue removal mechanism coupled to the handheld housing. The tissue removal mechanism may comprise a tissue collection chamber coupled to a distal portion of the handheld housing, a jaw member comprising first and second jaw portions, where the first jaw portion is coupled to a first elongated member and the second jaw portion is coupled to a second elongated member configured to actuate the second jaw portion, a rotatable shaft disposed within a lumen of the first elongated member, a helical member disposed around at least a portion of the rotatable shaft, and an impeller coupled to at least one of a distal end of the helical member and a distal end of the rotatable shaft. Rotation of the rotatable shaft may effect rotation of the helical member and the impeller.
摘要翻译：组织去除装置可以包括手持壳体，马达和联接到手持壳体的组织去除机构。组织移除机构可以包括联接到手持式壳体的远端部分的组织收集腔，包括第一和第二钳口部分的钳口构件，其中第一钳口部分联接到第一细长构件，并且第二钳口部分联接到构造成致动所述第二钳口部分的第二细长构件，设置在所述第一细长构件的内腔内的可旋转轴，围绕所述可旋转轴的至少一部分设置的螺旋构件，以及联接到远端螺旋构件的端部和可旋转轴的远端。旋转轴的旋转可能影响螺旋构件和叶轮的旋转。

9. 发明申请

US20050177182A1 System and method for delivering a left atrial appendage containment device 审中-公开
标题翻译：用于递送左心耳遏制装置的系统和方法
公开(公告)号：US20050177182A1
公开(公告)日：2005-08-11
申请号：US11003696
申请日：2004-12-03
申请人： Erik van der Burg , Stewart Kume
发明人： Erik van der Burg , Stewart Kume
IPC分类号： A61B17/00 , A61B17/08 , A61B17/12
CPC分类号： A61F2/01 , A61B17/0057 , A61B17/12022 , A61B17/12122 , A61B17/12172 , A61B2017/003 , A61B2017/00575 , A61B2017/00579 , A61B2017/00592 , A61B2017/00597 , A61B2017/00615 , A61B2017/00623 , A61B2017/00632 , A61B2017/12054 , A61B2017/12095 , A61F2/013 , A61F2/243 , A61F2/2439 , A61F2/966 , A61F2002/018 , A61F2002/9505 , A61F2002/9511 , A61F2002/9665 , A61F2230/0006 , A61F2230/0071 , A61F2230/008
摘要： A method of delivering and deploying the device for containing the emboli during a surgical procedure proximate to the heart. Access is gained to the heart and the left atrium such that a distal end of the delivery sheath can be located near the left atrial appendage. A distal end of a delivery catheter can be loaded with the device in a collapsed position and passed through the delivery sheath thereby delivering the device within the left atrial appendage. The device is expanded to contain emboli in the left atrium appendage.
摘要翻译：在靠近心脏的外科手术过程中递送和展开用于容纳栓塞的装置的方法。获得进入心脏和左心房，使得输送鞘的远端可以位于左心耳附近。输送导管的远端可以装载在折叠位置并且穿过输送护套，从而将装置输送到左心耳内。该装置扩展为在左心房附属物中含有栓塞。

10. 发明授权

US06322548B1 Delivery catheter system for heart chamber 失效
标题翻译：心室输送导管系统
公开(公告)号：US06322548B1
公开(公告)日：2001-11-27
申请号：US09052971
申请日：1998-03-31
申请人： Sam G. Payne , Randy J. Kesten , Michael Aita , Stewart Kume , Stephen B. Pearce , Manuel A. Javier, Jr. , Michael H. Rosenthal
发明人： Sam G. Payne , Randy J. Kesten , Michael Aita , Stewart Kume , Stephen B. Pearce , Manuel A. Javier, Jr. , Michael H. Rosenthal
IPC分类号： A61M3100
CPC分类号： A61B18/24 , A61B17/0218 , A61B17/32002 , A61B17/3203 , A61B17/3478 , A61B18/12 , A61B90/39 , A61B2017/00243 , A61B2017/00247 , A61B2017/003 , A61B2017/22082 , A61B2017/2905 , A61B2017/2927 , A61B2017/320004 , A61B2017/3488 , A61B2018/00392 , A61B2090/036 , A61M25/0041 , A61M25/0084 , A61M25/0662 , A61M2025/0089 , A61M2210/125
摘要： A delivery catheter system for delivering a substance delivery member into a patient's left ventricle which includes a first delivery catheter with a shaped distal extremity configured to be aligned with or parallel to a longitudinal axis or long dimension of the patient's left ventricle and a second delivery catheter slidably and rotatably disposed within an inner lumen of the first delivery catheter which has a shaped distal shaft section and an inner lumen configured to slidably receive a substance delivery member such as an elongated cannula slidably disposed within a polymer sheath. The shaped distal section of the first delivery catheter is shaped or is shapeable within the patient's heart chamber. The second delivery catheter is advanced out of the inner lumen of the first delivery catheter until the distal end extends out of the port in the distal end of the first delivery catheter and provides a passageway for substance delivery member to engage the endocardial surface at a perpendicular or near perpendicular orientation.
摘要翻译：一种输送导管系统，用于将物质递送部件输送到患者的左心室中，该输送导管系统包括具有成形远端的第一输送导管，该第一输送导管被构造为与患者的左心室的纵向轴线或长度尺寸对准或平行，可滑动地和可旋转地设置在第一输送导管的内腔内，该第一输送导管具有成形的远端轴部分和内腔，其构造成可滑动地容纳诸如可滑动地设置在聚合物护套内的细长插管的物质输送构件。第一输送导管的形状的远端部分在患者的心室内成形或可成形。第二输送导管从第一输送导管的内腔推出，直到远端从第一输送导管的远端中的端口延伸出来，并且提供用于物质输送构件在垂直方向上接合心内膜表面的通道或近垂直取向。

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