专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明授权

US5064840A Anti-psychotic piperidylbenzimidazole compounds 失效
标题翻译：抗精神病性哌啶基苯并咪唑化合物
公开(公告)号：US5064840A
公开(公告)日：1991-11-12
申请号：US511893
申请日：1990-04-10
申请人： Albert A. Carr , Francis P. Miller , John M. Kane
发明人： Albert A. Carr , Francis P. Miller , John M. Kane
IPC分类号： C07D401/06
CPC分类号： C07D401/06
摘要： The present invention is directed to a new class of therapeutic agent which are useful as anti-psychotic agents and as analgesics.
摘要翻译：本发明涉及可用作抗精神病药和镇痛剂的新类治疗剂。

2. 发明授权

US5292752A Antithrombotic compounds 失效
标题翻译：抗血栓化合物
公开(公告)号：US5292752A
公开(公告)日：1994-03-08
申请号：US847971
申请日：1992-03-05
申请人： Albert A. Carr , Richard C. Dage , John E. Koerner , Tung Li , Francis P. Miller , Thaddeus R. Nieduzak
发明人： Albert A. Carr , Richard C. Dage , John E. Koerner , Tung Li , Francis P. Miller , Thaddeus R. Nieduzak
IPC分类号： C07D211/32 , A61K31/445
CPC分类号： C07D211/32 , Y10S514/81 , Y10S514/811 , Y10S514/812 , Y10S514/813 , Y10S514/821 , Y10S514/822
摘要： The present invention is directed to a new class of piperidinyl medicinal agents which are useful as antithrombotic agents and as serotonin 5HT.sub.2 antagonists.
摘要翻译：本发明涉及可用作抗血栓形成剂和5-羟色胺5HT 2拮抗剂的新一类哌啶基药物。

3. 发明授权

US4870083A 1,4-Disubstituted-piperidinyl compounds useful as analgesics and muscle relaxants 失效
标题翻译：可用作镇痛药和肌肉松弛剂的1,4-二取代哌啶基化合物
公开(公告)号：US4870083A
公开(公告)日：1989-09-26
申请号：US254208
申请日：1988-10-11
申请人： Albert A. Carr , Thaddeus R. Nieduzak , Francis P. Miller , Stephen M. Sorensen
发明人： Albert A. Carr , Thaddeus R. Nieduzak , Francis P. Miller , Stephen M. Sorensen
IPC分类号： A61K31/445 , A61K31/4465 , A61P25/04 , C07D211/22
CPC分类号： C07D211/22
摘要： The present invention relates to 1,4-disubstituted-piperidinyl compounds and their use as analgesic agents and as muscle relaxants.

4. 发明授权

US5500433A Method of treating drug abuse 失效
标题翻译：治疗药物滥用的方法
公开(公告)号：US5500433A
公开(公告)日：1996-03-19
申请号：US371063
申请日：1995-01-10
申请人： Albert A. Carr , Richard C. Dage , John E. Koerner , Tung Li , Francis P. Miller , Thaddeus R. Nieduzak , Mark W. Dudley , . Christopher J. Schmidt , Robert A. Frank
发明人： Albert A. Carr , Richard C. Dage , John E. Koerner , Tung Li , Francis P. Miller , Thaddeus R. Nieduzak , Mark W. Dudley , . Christopher J. Schmidt , Robert A. Frank
IPC分类号： C07D211/32 , A61K31/445
CPC分类号： C07D211/32 , Y10S514/81 , Y10S514/811 , Y10S514/812 , Y10S514/813 , Y10S514/821 , Y10S514/822
摘要： The present invention is directed to a new class of piperidinyl medicinal agents which are useful for treating drug abuse.
摘要翻译：本发明涉及可用于治疗药物滥用的新一类哌啶基药物。

5. 发明授权

US5166211A Method of using 1,4-disubstituted piperidinyl compounds in the treatment of coronary vasospasons and variant angina 失效
标题翻译：使用1,4-二取代哌啶基化合物治疗冠状动脉血管痉挛和变异型心绞痛的方法
公开(公告)号：US5166211A
公开(公告)日：1992-11-24
申请号：US797643
申请日：1991-12-16
申请人： Albert A. Carr , Richard C. Dage , John E. Koerner , Tung Li , Francis P. Miller
发明人： Albert A. Carr , Richard C. Dage , John E. Koerner , Tung Li , Francis P. Miller
IPC分类号： C07D211/22 , C07D211/28 , C07D211/32
CPC分类号： C07D211/28 , C07D211/22 , C07D211/32 , Y10S514/929
摘要： The present invention pertains to a new class of compounds which can be characterized as 1,4-disubstituted piperidinyl compounds useful as antiarrhythmics, analgesics, and serotonin 5HT.sub.2 antagonists.
摘要翻译：本发明涉及一类新的化合物，其可以表征为用作抗心律失常药，止痛剂和5-羟色胺5HT2拮抗剂的1,4-二取代哌啶基化合物。

6. 发明授权

US5093341A N-aralkyl piperidine derivatives useful as antithrombolytic agents 失效
标题翻译：用作抗凝剂的N-阿拉基哌啶衍生物
公开(公告)号：US5093341A
公开(公告)日：1992-03-03
申请号：US237600
申请日：1988-08-26
申请人： Albert A. Carr , John E. Koerner , Richard C. Dage , Tung Li , Francis P. Miller
发明人： Albert A. Carr , John E. Koerner , Richard C. Dage , Tung Li , Francis P. Miller
IPC分类号： C07C62/38 , A61K31/445 , A61K31/451 , A61P9/00 , C07C51/00 , C07C51/353 , C07C67/00 , C07C69/757 , C07C69/94 , C07C69/95 , C07C201/00 , C07C205/37 , C07C205/59 , C07C205/61 , C07D20060101 , C07D211/22 , C07D211/26 , C07D211/28 , C07D211/32 , C07D307/00 , C07D307/70 , C07D307/92 , C07D317/44 , C07D317/48 , C07D317/70 , C07D493/04 , C07D493/06 , C07D493/08 , C07F7/18
CPC分类号： C07D211/22 , C07D211/28 , C07D211/32 , C07D317/70 , C07D493/04 , C07D493/08 , C07F7/1856
摘要： The present invention is directed to a new class of compounds useful as antiarrhythmics, analgesics and serotonin 5HT.sub.2 antagonists, which compounds have the following formula: ##STR1## wherein; Y is represented by H, CO(CH.sub.2).sub.n CH.sub.3 in which n is an integer from 0-3, or SO.sub.2 (CH.sub.2).sub.n CH.sub.3 in which n is an integer from 0--3; X is represented CO, CHOH, or C.dbd.N--O--A, wherein A is represented by hydrogen or a C.sub.1-4 alkyl; R is either selected from the group consisting of halogens, lower alkyl groups, lower alkoxy groups, and hydrogen or R is a divalent substituent and is represented by a 3,4-methylenedioxy or a 3,4-ethylenedioxy substituent; m is an integer from 1-5; and the pharmaceutically acceptable acid addition salts thereof.

7. 发明授权

US5650416A Piperidinyl thiacyclic derivatives 失效
公开(公告)号：US5650416A
公开(公告)日：1997-07-22
申请号：US449615
申请日：1995-05-24
申请人： Albert A. Carr , John M. Kane , George D. Maynard , Hsien C. Cheng , Mark W. Dudley
发明人： Albert A. Carr , John M. Kane , George D. Maynard , Hsien C. Cheng , Mark W. Dudley
IPC分类号： A61K31/4433 , A61K31/445 , A61K31/454 , A61P37/08 , C07D409/06 , C07D409/14 , C07D417/06 , C07D417/14 , C07D417/02
CPC分类号： C07D409/06 , C07D409/14 , C07D417/06 , C07D417/14
摘要： Piperidinyl thiacyclic derivatives of the formula ##STR1## wherein X, Y, R.sub.1, R.sub.2, R.sub.3 and R.sub.4 are defined in the specification, are useful in the treatment of allergic diseases and diseases responding to antagonism of 5HT.sub.2 receptors. Pharmaceutical compositions and methods of treatment using these compounds are also disclosed.

8. 发明授权

US5631268A Piperidinyl thiacyclic derivatives 失效
标题翻译：哌啶基硫辛酸衍生物
公开(公告)号：US5631268A
公开(公告)日：1997-05-20
申请号：US449034
申请日：1995-05-24
申请人： Albert A. Carr , John M. Kane , George D. Maynard , Hsien C. Cheng , Mark W. Dudley
发明人： Albert A. Carr , John M. Kane , George D. Maynard , Hsien C. Cheng , Mark W. Dudley
IPC分类号： A61K31/4433 , A61K31/445 , A61K31/454 , A61P37/08 , C07D409/06 , C07D409/14 , C07D417/06 , C07D417/14 , C07D417/02
CPC分类号： C07D409/06 , C07D409/14 , C07D417/06 , C07D417/14
摘要： Piperidinyl thiacyclic derivatives of the formula ##STR1## wherein X, Y, R.sub.1, R.sub.2, R.sub.3 and R.sub.4 are defined in the specification, are useful in the treatment of allergic diseases and diseases responding to antagonism of 5HT.sub.2 receptors. Pharmaceutical compositions and methods of treatment using these compounds are also disclosed.
摘要翻译：其中X，Y，R 1，R 2，R 3和R 4在本说明书中定义的式IMA图形的哌啶基thiacyclic衍生物可用于治疗对5HT2受体拮抗作用的过敏性疾病和疾病。还公开了使用这些化合物的药物组合物和治疗方法。

9. 发明授权

US4341698A Enkaphalin derivatives 失效
标题翻译：恩考芬素衍生物
公开(公告)号：US4341698A
公开(公告)日：1982-07-27
申请号：US130431
申请日：1980-03-14
申请人： Albert A. Carr , Robert A. Farr , John M. Kane
发明人： Albert A. Carr , Robert A. Farr , John M. Kane
IPC分类号： A61K38/00 , C07D241/08 , C07K5/078 , C07K5/117 , C07C103/52
CPC分类号： C07K5/06139 , C07D241/08 , C07K5/1024 , A61K38/00
摘要： Novel analgesic and antipsychotic agents having the formula ##STR1## wherein Q is ##STR2## in which R.sub.1 is hydrogen, hydroxy or halogen and R.sub.4 is hydrogen or, R.sub.1 and R.sub.4 are both hydroxy; Z is hydrogen or straight chain lower alkyl having from 1 to 4 carbon atoms and X is methylene, carbonyl, hydroxymethylene, thio, sulfinyl or sulfonyl, or Z and X, taken together, are methylidenyl, with the proviso that when X is sulfonyl or sulfinyl, Z is other than hydrogen; R.sub.5 is hydrogen or halogen, and R.sub.2 is H, a straight or branched lower alkyl group having from 1 to 4 carbon atoms, the group ##STR3## or the group ##STR4## wherein R.sub.3 is hydroxy, amino, alkylamino or dialkylamino wherein the alkyl moiety is straight or branched and has from 1 to 4 carbon atoms, diastereomers, enantiomers and pharmaceutically acceptable salts thereof.
摘要翻译：其中Q为的新型止痛剂和抗精神病药，其中R1为氢，羟基或卤素，R4为氢或R1和R4均为羟基; Z是氢或具有1至4个碳原子的直链低级烷基，X是亚甲基，羰基，羟基亚甲基，硫代，亚磺酰基或磺酰基，或Z和X一起是亚甲基，条件是当X是磺酰基或亚磺酰基，Z不是氢; R 5是氢或卤素，R 2是H，具有1至4个碳原子的直链或支链低级烷基，基团“IMAGE”或基团“IMAGE”，其中R 3是羟基，氨基，烷基氨基或二烷基氨基，其中烷基部分是直链或支链的并且具有1至4个碳原子，非对映异构体，对映异构体和药学上可接受的盐。

10. 发明授权

US5162342A Use of 1,4-disubstituted-piperidinyl compounds for analgesia and muscle relaxation 失效
标题翻译：用于麻醉和松弛放松的1,4-二异丁基哌啶化合物的应用
公开(公告)号：US5162342A
公开(公告)日：1992-11-10
申请号：US725704
申请日：1991-07-03
申请人： Albert A. Carr , Francis P. Miller , Thaddeus R. Nieduzak , Stephen M. Sorensen
发明人： Albert A. Carr , Francis P. Miller , Thaddeus R. Nieduzak , Stephen M. Sorensen
IPC分类号： C07D211/22 , C07D211/32
CPC分类号： C07D211/22 , C07D211/32 , Y10S514/906
摘要： The present invention relates to 1,4-disubstituted-piperidinyl compounds that have utility as analgesics and as muscle relaxants.
摘要翻译：本发明涉及作为止痛剂和肌肉松弛剂有用的1,4-二取代哌啶基化合物。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式