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1. 发明授权

US5876367A Cerebral protection during carotid endarterectomy and downstream vascular protection during other surgeries 失效
公开(公告)号：US5876367A
公开(公告)日：1999-03-02
申请号：US759591
申请日：1996-12-05
申请人： Alan L. Kaganov , Jonathan D. Root , John McKenzie
发明人： Alan L. Kaganov , Jonathan D. Root , John McKenzie
IPC分类号： A61B17/22 , A61F2/01 , A61M25/00 , A61M29/02 , A61M5/00
CPC分类号： A61F2/013 , A61B17/22 , A61F2/01 , A61F2002/011 , A61F2002/018 , A61F2230/0006 , A61F2230/0067 , A61F2230/0093 , A61M2025/0079 , A61M2025/1097 , A61M25/0097
摘要： A shunt and method of use for maintaining distal blood flow during an arteriotomy procedure is disclosed. The shunt includes a first tubular member having a proximal end, a distal end, and a lumen therebetween. The proximal end has an opening in communication with the lumen, and the proximal opening is adapted to receive blood from a first region of an artery. The distal end has an opening in communication with the lumen, and the distal opening is adapted to release blood into a second region of the artery. The shunt includes a second tubular member having a proximal end, a distal end, and a lumen therebetween which either merges and communicates at its distal end with the lumen of the first tubular member, or rides separate and parallel to it. The shunt also includes a hemostatic valve attached to the proximal end of the second tubular member, the valve acting to prevent loss of blood from the lumen of the second tubular member and to permit the introduction of a medical device into the lumen of the second tubular member and into the artery. In use, the distal opening of the shunt is inserted into the second region of an artery and secured to the lumen of the artery. A blood filter device is deployed within the artery. The proximal opening of the shunt is inserted into the first region of the artery and secured to the lumen of the artery. Endarterectomy is performed on the region of the artery which lies between the proximal opening and the distal opening of the shunt, and embolic material dislodged during the procedure is captured by the filter.

2. 发明授权

US06689084B2 Cerebral protection during carotid endarterectomy and downstream vascular protection during other surgeries 有权
标题翻译：颈动脉内膜切除术期间的脑保护及其他手术中的下游血管保护
公开(公告)号：US06689084B2
公开(公告)日：2004-02-10
申请号：US10366117
申请日：2003-02-12
申请人： Alan L. Kaganov , Jonathan D. Root , John McKenzie
发明人： Alan L. Kaganov , Jonathan D. Root , John McKenzie
IPC分类号： A61M500
CPC分类号： A61F2/013 , A61B17/22 , A61F2/01 , A61F2002/011 , A61F2002/018 , A61F2230/0006 , A61F2230/0067 , A61F2230/0093 , A61M25/0097 , A61M2025/0079 , A61M2025/1097
摘要： A method for carotid endarterectomy. A blood filter is positioned within a carotid artery downstream of an atheromatous plaque. The filter is expanded. The carotid artery is clamped upstream and downstream of the atheromatous plaque while the filter is expanded. An endarterectomy procedure is performed on the region of the carotid artery having the atheromatous plaque. The carotid artery is unclamped while the filter is expanded. In certain cases a shunt is positioned in a region of the carotid artery having the atheromatous plaque and secured to the shunt by clamping, the shunt comprising a tubular member having a proximal opening, a distal opening, and a lumen therebetween.
摘要翻译：颈动脉内膜切除术的一种方法。血液过滤器位于动脉粥样硬化斑块下游的颈动脉内。过滤器扩展。当过滤器膨胀时，颈动脉夹在动脉粥样硬化斑块的上游和下游。在具有动脉粥样硬化斑块的颈动脉的区域进行内膜切除术。当过滤器膨胀时，颈动脉松开。在某些情况下，分流器位于具有动脉粥样硬化斑块的颈动脉的区域中，并通过夹紧固定到分流器，分流器包括具有近端开口，远端开口和其间的内腔的管状构件。

3. 发明授权

US6074357A Cerebral protection during carotid endarterectomy and downstream vascular protection during other surgeries 有权
公开(公告)号：US6074357A
公开(公告)日：2000-06-13
申请号：US176145
申请日：1998-10-21
申请人： Alan L. Kaganov , Jonathan D. Root , John McKenzie
发明人： Alan L. Kaganov , Jonathan D. Root , John McKenzie
IPC分类号： A61B17/22 , A61F2/01 , A61M25/00 , A61M29/02 , A61M5/00
CPC分类号： A61F2/013 , A61B17/22 , A61F2/01 , A61F2002/011 , A61F2002/018 , A61F2230/0006 , A61F2230/0067 , A61F2230/0093 , A61M2025/0079 , A61M2025/1097 , A61M25/0097
摘要： A shunt and method of use for maintaining distal blood flow during an arteriotomy procedure is disclosed. The shunt includes a first tubular member having a proximal end, a distal end, and a lumen therebetween. The proximal end has an opening in communication with the lumen, and the proximal opening is adapted to receive blood from a first region of an artery. The distal end has an opening in communication with the lumen, and the distal opening is adapted to release blood into a second region of the artery. The shunt includes a second tubular member having a proximal end, a distal end, and a lumen therebetween which either merges and communicates at its distal end with the lumen of the first tubular member, or rides separate and parallel to it. The shunt also includes a hemostatic valve attached to the proximal end of the second tubular member, the valve acting to prevent loss of blood from the lumen of the second tubular member and to permit the introduction of a medical device into the lumen of the second tubular member and into the artery. In use, the distal opening of the shunt is inserted into the second region of an artery and secured to the lumen of the artery. A blood filter device is deployed within the artery. The proximal opening of the shunt is inserted into the first region of the artery and secured to the lumen of the artery. Endarterectomy is performed on the region of the artery which lies between the proximal opening and the distal opening of the shunt, and embolic material dislodged during the procedure is captured by the filter.

4. 发明授权

US06551268B1 Cerebral protection during carotid endarterectomy and downstream vascular protection during other surgeries 有权
标题翻译：颈动脉内膜切除术期间的脑保护及其他手术中的下游血管保护
公开(公告)号：US06551268B1
公开(公告)日：2003-04-22
申请号：US09550356
申请日：2000-04-14
申请人： Alan L. Kaganov , Jonathan D. Root , John McKenzie
发明人： Alan L. Kaganov , Jonathan D. Root , John McKenzie
IPC分类号： A61M500
CPC分类号： A61F2/013 , A61B17/22 , A61F2/01 , A61F2002/011 , A61F2002/018 , A61F2230/0006 , A61F2230/0067 , A61F2230/0093 , A61M25/0097 , A61M2025/0079 , A61M2025/1097
摘要： A shunt and method of use for maintaining distal blood flow during an arteriotomy procedure is disclosed. The shunt includes a first tubular member having a proximal end, a distal end, and a lumen therebetween. The proximal end has an opening in communication with the lumen, and the proximal opening is adapted to receive blood from a first region of an artery. The distal end has an opening in communication with the lumen, and the distal opening is adapted to release blood into a second region of the artery. The shunt includes a second tubular member having a proximal end, a distal end, and a lumen therebetween which either merges and communicates at its distal end with the lumen of the first tubular member, or rides separate and parallel to it. The shunt also includes a hemostatic valve attached to the proximal end of the second tubular member, the valve acting to prevent loss of blood from the lumen of the second tubular member and to permit the introduction of a medical device into the lumen of the second tubular member and into the artery. In use, the distal opening of the shunt is inserted into the second region of an artery and secured to the lumen of the artery. A blood filter device is deployed within the artery. The proximal opening of the shunt is inserted into the first region of the artery and secured to the lumen of the artery. Endarterectomy is performed on the region of the artery which lies between the proximal opening and the distal opening of the shunt, and embolic material dislodged during the procedure is captured by the filter.
摘要翻译：公开了一种用于在动脉切开术过程中维持远端血流的分流和使用方法。分流器包括具有近端，远端和其间的内腔的第一管状构件。近端具有与内腔连通的开口，并且近端开口适于从动脉的第一区域接收血液。远端具有与内腔连通的开口，并且远侧开口适于将血液释放到动脉的第二区域中。分流器包括具有近端，远端和其间的腔的第二管状构件，其在其远端处与第一管状构件的内腔合并并连通，或者与其分开并平行。所述分流器还包括附接到所述第二管状构件的近端的止血阀，所述止血阀用于防止来自所述第二管状构件的内腔的血液的损失并且允许将医疗装置引入到所述第二管状构件的内腔中成员进入动脉。在使用中，分流器的远端开口插入动脉的第二区域并固定到动脉的内腔。血液过滤装置部署在动脉内。分流器的近侧开口插入动脉的第一区域并固定到动脉的内腔。在位于分流器的近端开口和远端开口之间的动脉区域进行内膜切除术，并且在手术过程中被移除的栓塞物质被过滤器捕获。

5. 发明授权

US5895399A Atherectomy device having trapping and excising means for removal of plaque from the aorta and other arteries 失效
公开(公告)号：US5895399A
公开(公告)日：1999-04-20
申请号：US728035
申请日：1996-10-09
申请人： Denise Barbut , Jonathan D Root , Robert Rizzari , James M Sellers , Giovanni Pastrone , John McKenzie
发明人： Denise Barbut , Jonathan D Root , Robert Rizzari , James M Sellers , Giovanni Pastrone , John McKenzie
IPC分类号： A61B10/00 , A61B10/02 , A61B10/06 , A61B17/00 , A61B17/22 , A61B17/30 , A61B17/32 , A61F2/01 , A61M25/00
CPC分类号： A61B17/320783 , A61B17/22031 , A61B17/221 , A61B17/3207 , A61F2/01 , A61F2/013 , A61B10/06 , A61B17/32056 , A61B17/32075 , A61B2010/0225 , A61B2017/00287 , A61B2017/22068 , A61B2017/22069 , A61B2017/2215 , A61B2017/306 , A61B2017/32004 , A61B2017/320064 , A61B8/0808 , A61F2002/018 , A61F2230/0006 , A61F2230/0067 , A61F2230/0071 , A61F2230/008 , A61M2210/127 , A61M25/00
摘要： An arterial catheter system for removing plaque from the aorta and other arteries is disclosed. The system typically includes an elongate catheter member, a filtration apparatus disposed within the distal region, and an atherectomy assembly which includes a mechanism for trapping and holding mobile or fixed plaque and an excising mechanism for removing the plaque. In use, the catheter is positioned so that the atherectomy assembly lies within a region of interest, the filtration apparatus is deployed downstream of the region of interest, the plaque is trapped and held by a snare, vacuum, or other trapping means, and then the excising mechanism is activated to remove the plaque. Methods are also disclosed for removing plaque from the aorta and other arteries.

6. 发明授权

US6010522A Atherectomy device having trapping and excising means for removal of plaque from the aorta and other arteries 失效
标题翻译：动脉粥样硬化切除装置具有用于从主动脉和其他动脉移除斑块的捕获和切除装置
公开(公告)号：US6010522A
公开(公告)日：2000-01-04
申请号：US685577
申请日：1996-07-24
申请人： Denise Barbut , Jonathan D Root , Robert Rizzari , James M Sellers , Giovanni Pastrone , John McKenzie
发明人： Denise Barbut , Jonathan D Root , Robert Rizzari , James M Sellers , Giovanni Pastrone , John McKenzie
IPC分类号： A61B10/00 , A61B10/02 , A61B10/06 , A61B17/00 , A61B17/22 , A61B17/30 , A61B17/32 , A61F2/01 , A61M25/00 , A61M29/00
CPC分类号： A61B17/320783 , A61B17/22031 , A61B17/221 , A61B17/3207 , A61F2/01 , A61F2/013 , A61B10/06 , A61B17/32056 , A61B17/32075 , A61B2010/0225 , A61B2017/00287 , A61B2017/22068 , A61B2017/22069 , A61B2017/2215 , A61B2017/306 , A61B2017/32004 , A61B2017/320064 , A61B8/0808 , A61F2002/018 , A61F2230/0006 , A61F2230/0067 , A61F2230/0071 , A61F2230/008 , A61M2210/127 , A61M25/00
摘要： An arterial catheter system for removing plaque from the aorta and other arteries is disclosed. The system typically includes an elongate catheter member, a filtration apparatus disposed within the distal region, and an atherectomy assembly which includes a mechanism for trapping and holding mobile or fixed plaque and an excising mechanism for removing the plaque. In use, the catheter is positioned so that the atherectomy assembly lies within a region of interest, the filtration apparatus is deployed downstream of the region of interest, the plaque is trapped and held by a snare, vacuum, or other trapping means, and then the excising mechanism is activated to remove the plaque. Methods are also disclosed for removing plaque from the aorta and other arteries.
摘要翻译：公开了用于从主动脉和其它动脉移除斑块的动脉导管系统。该系统通常包括细长导管构件，设置在远侧区域内的过滤装置，以及动脉粥样组织切除组件，其包括用于捕获和保持移动或固定噬菌斑的机构和用于去除斑块的切除机构。在使用中，定位导管，使得动脉切除术组件位于感兴趣的区域内，过滤装置部署在感兴趣区域的下游，斑块被圈套，真空或其它捕获装置捕获并保持，然后激活切除机制以去除斑块。还公开了从主动脉和其他动脉中除去斑块的方法。

7. 发明授权

US5997557A Methods for aortic atherectomy 失效
标题翻译：主动脉粥样斑块切除术的方法
公开(公告)号：US5997557A
公开(公告)日：1999-12-07
申请号：US22179
申请日：1998-02-11
申请人： Denise Barbut , Jonathan D. Root , Robert Rizzari , James M. Sellers , Giovanni Pastrone , John McKenzie
发明人： Denise Barbut , Jonathan D. Root , Robert Rizzari , James M. Sellers , Giovanni Pastrone , John McKenzie
IPC分类号： A61B10/00 , A61B10/02 , A61B10/06 , A61B17/00 , A61B17/22 , A61B17/30 , A61B17/32 , A61F2/01 , A61M25/00
CPC分类号： A61B17/320783 , A61B17/22031 , A61B17/221 , A61B17/3207 , A61F2/01 , A61F2/013 , A61B10/06 , A61B17/32056 , A61B17/32075 , A61B2010/0225 , A61B2017/00287 , A61B2017/22068 , A61B2017/22069 , A61B2017/2215 , A61B2017/306 , A61B2017/32004 , A61B2017/320064 , A61B8/0808 , A61F2002/018 , A61F2230/0006 , A61F2230/0067 , A61F2230/0071 , A61F2230/008 , A61M2210/127 , A61M25/00
摘要： An arterial catheter system for removing plaque from the aorta and other arteries is disclosed. The system typically includes an elongate catheter member, a filtration apparatus disposed within the distal region, and an atherectomy assembly which includes a mechanism for trapping and holding mobile or fixed plaque and an excising mechanism for removing the plaque. In use, the catheter is positioned so that the atherectomy assembly lies within a region of interest, the filtration apparatus is deployed downstream of the region of interest, the plaque is trapped and held by a snare, vacuum, or other trapping means, and then the excising mechanism is activated to remove the plaque. Methods are also disclosed for removing plaque from the aorta and other arteries.
摘要翻译：公开了用于从主动脉和其它动脉移除斑块的动脉导管系统。该系统通常包括细长导管构件，设置在远侧区域内的过滤装置，以及动脉粥样组织切除组件，其包括用于捕获和保持移动或固定噬菌斑的机构和用于去除斑块的切除机构。在使用中，定位导管，使得动脉切除术组件位于感兴趣的区域内，过滤装置部署在感兴趣区域的下游，斑块被圈套，真空或其它捕获装置捕获并保持，然后激活切除机制以去除斑块。还公开了从主动脉和其他动脉中除去斑块的方法。

8. 发明授权

US5662671A Atherectomy device having trapping and excising means for removal of plaque from the aorta and other arteries 失效
标题翻译：动脉粥样硬化切除装置具有用于从主动脉和其他动脉移除斑块的捕获和切除装置
公开(公告)号：US5662671A
公开(公告)日：1997-09-02
申请号：US683503
申请日：1996-07-17
申请人： Denise Barbut , Jonathan D. Root , Robert Rizzari , James M. Sellers , Giovanni Pastrone , John McKenzie
发明人： Denise Barbut , Jonathan D. Root , Robert Rizzari , James M. Sellers , Giovanni Pastrone , John McKenzie
IPC分类号： A61B10/00 , A61B10/02 , A61B10/06 , A61B17/00 , A61B17/22 , A61B17/30 , A61B17/32 , A61F2/01 , A61M25/00
CPC分类号： A61B17/320783 , A61B17/22031 , A61B17/221 , A61B17/3207 , A61F2/01 , A61F2/013 , A61B10/06 , A61B17/32056 , A61B17/32075 , A61B2010/0225 , A61B2017/00287 , A61B2017/22068 , A61B2017/22069 , A61B2017/2215 , A61B2017/306 , A61B2017/32004 , A61B2017/320064 , A61B8/0808 , A61F2002/018 , A61F2230/0006 , A61F2230/0067 , A61F2230/0071 , A61F2230/008 , A61M2210/127 , A61M25/00
摘要： An arterial catheter system for removing plaque from the aorta and other arteries is disclosed. The system typically includes an elongate catheter member, a filtration apparatus disposed within the distal region, and an atherectomy assembly which includes a mechanism for trapping and holding mobile or fixed plaque and an excising mechanism for removing the plaque. In use, the catheter is positioned so that the atherectomy assembly lies within a region of interest, the filtration apparatus is deployed downstream of the region of interest, the plaque is trapped and held by a snare, vacuum, or other trapping means, and then the excising mechanism is activated to remove the plaque. Methods are also disclosed for removing plaque from the aorta and other arteries.
摘要翻译：公开了用于从主动脉和其它动脉移除斑块的动脉导管系统。该系统通常包括细长导管构件，设置在远侧区域内的过滤装置，以及动脉粥样组织切除组件，其包括用于捕获和保持移动或固定噬菌斑的机构和用于去除斑块的切除机构。在使用中，定位导管，使得动脉切除术组件位于感兴趣的区域内，过滤装置部署在感兴趣区域的下游，斑块被圈套，真空或其它捕获装置捕获并保持，然后激活切除机制以去除斑块。还公开了从主动脉和其他动脉中除去斑块的方法。

9. 发明授权

US08034105B2 Ophthalmic implant for treatment of glaucoma 失效
标题翻译：用于治疗青光眼的眼科植入物
公开(公告)号：US08034105B2
公开(公告)日：2011-10-11
申请号：US11305306
申请日：2005-12-16
申请人： Robert Stegmann , Stanley R. Conston , David J. Kupiecki , John McKenzie , Candice D. Pinson , Ronald K. Yamamoto
发明人： Robert Stegmann , Stanley R. Conston , David J. Kupiecki , John McKenzie , Candice D. Pinson , Ronald K. Yamamoto
IPC分类号： A61F2/14 , A61M5/00
CPC分类号： A61F9/00781
摘要： A method is provided for increasing the outflow of fluid through Schlemm's canal that is useful for treatment of glaucoma. The implant is placed in Schlemm's canal by use of a flexible delivery instrument attached to the implant. The instrument and implant are positioned within the canal, the implant is released and the distal and proximal ends of the implant are connected to apply sufficient axial tensioning force on the inner wall of the canal to increase fluid permeability. In another embodiment a delivery instrument attached to the implant is positioned in the canal securing one of the distal or proximal ends of the implant within the canal. The implant provides sufficient axial tensioning force on the inner wall of the canal to increase fluid permeability of the inner wall of the canal. The other of the distal or proximal ends may be secured to maintain the tensioning force on the inner wall of the canal.
摘要翻译：提供了一种增加流体穿过施莱姆氏管的流出方法，可用于治疗青光眼。通过使用附着在植入物上的柔性递送器械将植入物置于施莱姆氏管中。仪器和植入物定位在管内，植入物被释放，并且植入物的远端和近端被连接以在管的内壁上施加足够的轴向张力以增加流体渗透性。在另一个实施例中，附接到植入物的递送器械定位在将移植物的远端或近端中的一端固定在管内的运河中。植入物在管道的内壁上提供足够的轴向张力，以增加管道内壁的流体渗透性。远端或近端中的另一个可以被固定以保持在管的内壁上的张紧力。

10. 发明申请

US20050127122A1 Universal Feature Attachment System 审中-公开
标题翻译：通用功能附件系统
公开(公告)号：US20050127122A1
公开(公告)日：2005-06-16
申请号：US10707432
申请日：2003-12-12
申请人： John McKenzie , Alan Sturt , Thomas Hicks , Jeff Kempf
发明人： John McKenzie , Alan Sturt , Thomas Hicks , Jeff Kempf
IPC分类号： B60R11/00 , B60R11/02 , B60R7/00 , B60R9/00
CPC分类号： B60R11/02 , B60R11/00 , B60R2011/0061 , B60R2011/0073 , B60R2011/0082
摘要： Disclosed is a universal, in-vehicle attachment system comprising open slots whereby a similarly shaped storage unit with complimentary prongs is inserted, providing a secure and easy fastening attachment device designed to secure devices and items in place within the vehicle such as, for example, cellular phones, CDs or DVDs, bottles, mugs, cups, coolers, bike racks, and PDAs. This in-vehicle storage or securing attachment system can be molded to conform directly to the size and shape of the particular object or, alternatively, a more generic type receptacle can be used to secure such items. Further, the in-vehicle attachment system is incorporated into the vehicle, with multiple locations, including the seat back panel, instrument panel, door panel, quarter panel, floor panel, or other interior surfaces.
摘要翻译：公开了一种通用的车载附件系统，其包括开口槽，由此插入具有互补叉的类似形状的存储单元，提供安全且容易的紧固附接装置，其被设计成将设备和物品固定在车辆内的适当位置，手机，CD或DVD，瓶子，杯子，杯子，冷却器，自行车架和PDA。该车载存储或固定附接系统可以被模制成直接符合特定物体的尺寸和形状，或者替代地，可以使用更通用的类型的容器来固定这些物品。此外，车载附件系统结合到车辆中，具有多个位置，包括座椅后面板，仪表板，门板，四分之一面板，地板镶板或其它内表面。

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