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1. 发明授权

US5739132A Pyridazinone derivatives and processes for preparing the same 失效
标题翻译：哒嗪酮衍生物及其制备方法
公开(公告)号：US5739132A
公开(公告)日：1998-04-14
申请号：US767444
申请日：1996-12-16
申请人： Akihiko Ishida , Koichi Homma , Harumichi Kono , Koji Tamura , Yasuhiko Sasaki
发明人： Akihiko Ishida , Koichi Homma , Harumichi Kono , Koji Tamura , Yasuhiko Sasaki
IPC分类号： C07D237/04 , A61K31/50
CPC分类号： C07D237/04
摘要： Disclosed are a pyridazinone compound represented by the formula: ##STR1## wherein (1) R.sup.1 is a substituted or unsubstituted C.sub.1-10 alkyl, a C.sub.3-6 cycloalkyl, a lower alkenyl, a heterocyclic group having N, O or S atom or camphor-10-yl; R.sup.3 is hydrogen, a substituted or unsubstituted lower alkyl or a lower alkenyl; or R.sup.1 and R.sup.3 are bonded at terminal ends thereof to form a lower alkylene; and Z is a group represented by the formula: ##STR2## where n is 1 or 2; and D is hydrogen or a halogen; or (2) R.sup.1 is a substituted or unsubstituted C.sub.1-10 alkyl, a substituted or unsubstituted phenyl, a C.sub.3-6 cycloalkyl, a lower alkenyl, a heterocyclic group having N, O or S atom or camphor-10-yl; R.sup.3 is hydrogen, a substituted or unsubstituted lower alkyl or a lower alkenyl; or R.sup.1 and R.sup.3 are bonded at terminal ends thereof to form a lower alkylene; and Z is a group represented by the formula: ##STR3## and R.sup.2 is hydrogen, a substituted or unsubstituted lower alkyl, an aryl or a lower alkenyl; and --A--B-- is an ethylene or vinylene each of which may be substituted by 1 or 2 groups selected from the group consisting of a lower alkyl and phenyl group, or a pharmaceutically acceptable salt thereof, and processes for preparing the same.
摘要翻译：公开了由下式表示的哒嗪酮化合物：其中（1）R1是取代或未取代的C1-10烷基，C3-6环烷基，低级烯基，具有N，O或S的杂环基原子或樟脑-10-基; R3是氢，取代或未取代的低级烷基或低级烯基; 或者R 1和R 3在其末端键合形成低级亚烷基; Z为由下式表示的基团：其中n为1或2; D为氢或卤素; 或（2）R1是取代或未取代的C1-10烷基，取代或未取代的苯基，C3-6环烷基，低级链烯基，具有N，O或S原子的杂环基或樟脑-10-基; R3是氢，取代或未取代的低级烷基或低级烯基; 或者R 1和R 3在其末端键合形成低级亚烷基; Z是由下式表示的基团：＆lt; IMAGE＆gt; R2是氢，取代或未取代的低级烷基，芳基或低级烯基; 并且-A-B-是各自可以被选自低级烷基和苯基的1或2个基团取代的乙烯或亚乙烯基，或其药学上可接受的盐及其制备方法。

2. 发明授权

US08049049B2 Method of upgrading biomass, upgraded biomass, biomass water slurry and method of producing same, upgraded biomass gas, and method of gasifying biomass 有权
标题翻译：升级生物质，升级生物质，生物质水泥浆及其生产方法，升级生物质气体和气化生物质的方法
公开(公告)号：US08049049B2
公开(公告)日：2011-11-01
申请号：US12264169
申请日：2008-11-03
申请人： Chiaki Suyama , Shinichi Tokuda , Masao Tsurui , Yoshinori Suto , Koji Tamura , Tsutomu Katagiri , Teruo Nagai , Jin Ogawa , Takeshi Yamaguchi
发明人： Chiaki Suyama , Shinichi Tokuda , Masao Tsurui , Yoshinori Suto , Koji Tamura , Tsutomu Katagiri , Teruo Nagai , Jin Ogawa , Takeshi Yamaguchi
IPC分类号： C07C1/00 , C10L5/00 , C10B53/08
CPC分类号： C10L1/326 , C10G31/08 , C10J3/00 , C10J2300/0916 , C10J2300/092 , C10J2300/0973 , C10J2300/1846 , C10L5/44 , C10L9/086 , C10L2250/06 , C10L2290/04 , C10L2290/24 , C10L2290/28 , Y02E50/10 , Y02E50/30
摘要： This method of upgrading a biomass comprises: an upgrading step for performing upgrading treatment of a cellulose based biomass with an oxygen/carbon atomic ratio of at least 0.5, in presence of water and under a pressure of at least saturated water vapor pressure, and reducing said oxygen/carbon atomic ratio of said biomass to no more than 0.38, and a separation step for separating an upgraded reactant obtained from said upgrading step into a solid component and a liquid component.
摘要翻译：这种升级生物质的方法包括：在水和至少饱和水蒸汽压的压力下，在氧/碳原子比为至少0.5的纤维素基生物质的基础上进行升级处理的升级步骤，并且还原所述生物质的氧/碳原子比不大于0.38，以及将从所述升级步骤获得的升级反应物分离成固体组分和液体组分的分离步骤。

3. 发明申请

US20060112638A1 Method of modifying biomass, modified biomass aqueous biomass sluryy and method of producing the same, modified biomass gas and method of gasifying biomass 失效
标题翻译：改良生物质，改性生物质含水生物质泥沙的方法及其生产方法，改良生物质气体和气化生物质的方法
公开(公告)号：US20060112638A1
公开(公告)日：2006-06-01
申请号：US10523749
申请日：2003-04-25
申请人： Chiaki Suyama , Shinichi Tokuda , Masao Tsurui , Yoshimori Suto , Koji Tamura , Tsutomu Katagiri , Teruo Nagai , Jin Ogawa , Takeshi Yamaguchi
发明人： Chiaki Suyama , Shinichi Tokuda , Masao Tsurui , Yoshimori Suto , Koji Tamura , Tsutomu Katagiri , Teruo Nagai , Jin Ogawa , Takeshi Yamaguchi
IPC分类号： C10J3/46
CPC分类号： C10L1/326 , C10G31/08 , C10J3/00 , C10J2300/0916 , C10J2300/092 , C10J2300/0973 , C10J2300/1846 , C10L5/44 , C10L9/086 , C10L2250/06 , C10L2290/04 , C10L2290/24 , C10L2290/28 , Y02E50/10 , Y02E50/30
摘要： This method of upgrading a biomass comprises: an upgrading step for performing upgrading treatment of a cellulose based biomass with an oxygen/carbon atomic ratio of at least 0.5, in presence of water and under a pressure of at least saturated water vapor pressure, and reducing said oxygen/carbon atomic ratio of said biomass to no more than 0.38, and a separation step for separating an upgraded reactant obtained from said upgrading step into a solid component and a liquid component.
摘要翻译：这种升级生物质的方法包括：在水和至少饱和水蒸汽压的压力下，在氧/碳原子比为至少0.5的纤维素基生物质的基础上进行升级处理的升级步骤，并且还原所述生物质的氧/碳原子比不大于0.38，以及将从所述升级步骤获得的升级反应物分离成固体组分和液体组分的分离步骤。

4. 发明授权

US5705382A Method for preserving nitrile hydratase or nitrilase activity of microbial cells with inorganic salts 失效
标题翻译：用无机盐保存微生物细胞的腈水合酶或腈水解酶活性的方法
公开(公告)号：US5705382A
公开(公告)日：1998-01-06
申请号：US542291
申请日：1995-10-12
申请人： Takakazu Endo , Toshiaki Doi , Koji Tamura , Yuji Hirata , Kouzo Murao
发明人： Takakazu Endo , Toshiaki Doi , Koji Tamura , Yuji Hirata , Kouzo Murao
IPC分类号： C12N11/00 , C12N1/04 , C12N11/14 , C12R1/01 , C12N1/12 , C12N9/96 , C12N11/04
CPC分类号： C12N1/04 , C12N11/14
摘要： Cells having enzyme activity, and the enzyme activity thereof, are preserved for a prolonged period of time, as a suspension of microbial cells or as a suspension of immobilized cells in particles, in an aqueous medium that is a neutral or weakly basic aqueous solution of inorganic salts, having a molarity ranging from 100 mM to the saturation concentration of the inorganic salts. Preferably, the microbial cells are cells containing the enzyme, nitrile hydratase or nitrilase, such as Gordona terrae or Rhodococcus rhodochrous, and the inorganic salts are phosphates, borates, sulfates, sulfites or hydrochlorides. The present invention provides an industrially useful method for preserving a large quantity of cells or immobilized cells in particles having nitrile hydratase or nitrilase enzyme activity for a prolonged period of time (e.g., 300 days) without cell lysis or enzyme deterioration even at room temperature. The present invention also renders possible a sharp reduction in labor and cooling cost, which are necessary in the conventional preservation process.
摘要翻译：具有酶活性的细胞及其酶活性在水性培养基中作为微生物细胞的悬浮液或作为固定化细胞的悬浮液在水性培养基中保持较长时间，其为中性或弱碱性水溶液无机盐，其摩尔浓度范围为100mM至无机盐的饱和浓度。优选地，微生物细胞是含有酶，腈水合酶或腈水解酶的细胞，例如戈多纳土壤或玫瑰色红玫瑰色，无机盐是磷酸盐，硼酸盐，硫酸盐，亚硫酸盐或盐酸盐。本发明提供一种工业上有用的方法，即使在室温下，即使在室温下，也不会在细胞裂解或酶劣化的情况下长时间（例如，300天），在具有腈水合酶或腈水解酶活性的颗粒中保存大量细胞或固定化细胞。本发明还使得在常规保存过程中必需的劳动和冷却成本急剧下降。

5. 发明授权

US5223416A Process for producing R(-)-mandelic acid and derivatives thereof 失效
标题翻译：制备R（ - ） - 马来酸及其衍生物的方法
公开(公告)号：US5223416A
公开(公告)日：1993-06-29
申请号：US677175
申请日：1991-03-29
申请人： Takakazu Endo , Koji Tamura
发明人： Takakazu Endo , Koji Tamura
IPC分类号： C12P7/42 , C12P41/00
CPC分类号： C12P41/006 , C12P7/42 , Y10S435/822 , Y10S435/829 , Y10S435/839 , Y10S435/84 , Y10S435/872 , Y10S435/874
摘要： A process for the predominantly producing R(-)-mandelic acid or a derivative thereof which comprises subjecting (i) R,S-mandelonitrile or a derivative thereof, or (ii) a mixture of prussic acid and benzaldehyde or a derivative of benzaldehyde to the action of a microorganism selected from the group consisting of the genus Aureobacterium, Pseudomonas, Caseobacter, Alcaligenes, Acinetobacter, Brevibacterium, Nocardia, and Bacillus or treated cells thereof, which the microorganism is capable of stereospecifically hydrolyzing a nitrile group of the R,S-mandelonitrile or a derivative thereof, in a neutral or basic aqueous reaction system to produce the R(-)-mandelic acid.

6. 发明授权

US5216679A Solid-state tunable laser resonator 失效
标题翻译：固态可调激光谐振器
公开(公告)号：US5216679A
公开(公告)日：1993-06-01
申请号：US688262
申请日：1991-04-22
申请人： Koji Tamura , Takashi Arisawa , Toku Shimizu
发明人： Koji Tamura , Takashi Arisawa , Toku Shimizu
IPC分类号： B01D59/34 , G01N3/00 , G02F1/35 , G02F1/37 , H01S3/094 , H01S3/1055 , H01S3/109 , H01S3/16
CPC分类号： H01S3/1055 , G02F1/3534 , G02F1/37 , H01S3/094 , H01S3/1625 , H01S3/1636
摘要： A solid state tunable laser resonator having a laser element, an excitation light source for outputting a pumping light, and elements for selecting a wavelength of the pumping light and directing the wavelength of the pumping light onto the laser element at a first point thereof on a first axis substantially parallel to an axis of oscillation light emitted by the laser element. The laser resonator may also include elements for directing the pumping light onto the laser element at a second additional point thereof. The laser resonator can be used as a laser light source having a wide tunable range with a narrow line width.
摘要翻译：一种具有激光元件的固体可调激光谐振器，用于输出泵浦光的激发光源，以及用于选择泵浦光的波长并将泵浦光的波长在其第一点上引导到激光元件上的元件，第一轴基本上平行于由激光元件发射的振荡光轴。激光谐振器还可以包括用于在其第二附加点处将泵浦光引导到激光元件上的元件。激光谐振器可以用作具有窄线宽宽的可调范围的激光光源。

7. 发明授权

US5035823A Refrigerant compositions of 1,11-trifluoroethane 失效
标题翻译： 1,11-三氟乙烷的制冷剂组合物
公开(公告)号：US5035823A
公开(公告)日：1991-07-30
申请号：US362385
申请日：1989-05-19
申请人： Koji Tamura , Hiroshi Kashiwagi , Masahiro Noguchi
发明人： Koji Tamura , Hiroshi Kashiwagi , Masahiro Noguchi
IPC分类号： F25B1/00 , C07K5/00 , C09K5/04
CPC分类号： C09K5/045 , C09K2205/122 , C09K2205/22
摘要： The present invention provides a refrigerant comprising 1,1,1-trifluoroethane and either chlorotetrafluoroethane or tetrafluoroethane.

8. 发明授权

US4983312A Refrigerants 失效
标题翻译：制冷剂
公开(公告)号：US4983312A
公开(公告)日：1991-01-08
申请号：US358364
申请日：1989-05-19
申请人： Koji Tamura , Hiroshi Kashiwagi , Masahiro Noguchi
发明人： Koji Tamura , Hiroshi Kashiwagi , Masahiro Noguchi
IPC分类号： C09K5/00 , C09K5/04 , C09K5/08 , F25B1/00
CPC分类号： C09K5/045 , C09K2205/122
摘要： The present invention provides a refrigerant comprising tetrafluoroethane and either chlorodifluoromethane or chlorodifluoroethane.

9. 发明授权

US08250898B2 Brake disk producing method and brake disk 有权
标题翻译：制动盘制作方法及制动盘
公开(公告)号：US08250898B2
公开(公告)日：2012-08-28
申请号：US12923587
申请日：2010-09-29
申请人： Tadashi Takenaka , Koji Tamura
发明人： Tadashi Takenaka , Koji Tamura
IPC分类号： B21D22/00 , B21D28/00
CPC分类号： F16D65/12 , F16D2065/026 , F16D2065/1316 , F16D2065/1392 , F16D2069/004 , F16D2200/0017 , F16D2200/003 , F16D2250/0023
摘要： A brake disk producing method, comprising a periphery pressing step for forming an outer peripheral shape (5) of a rotor plate (2) into a peripheral shape having recesses and ridges (5a, 5b) repeated in a radial direction, and a chamfering step for forming a chamfered surface (6) by pressing, against a corner portion (2d) on an outer peripheral edge of the rotor plate (2), a die (7), and a brake disk made by the method. Accordingly, it is possible to improve heat radiation capability, reduce the weight and moment of inertia, improve safety in handling, and suppress increase in production costs. Furthermore, by forming the chamfered surface (6), the amount of wear of a brake pad pressed by the brake disk (1) can be reduced, and durability of braking performance can be maintained or improved.
摘要翻译： 1.一种制动盘的制造方法，其特征在于，包括：外周加压工序，用于将转子板（2）的外周形状（5）形成为具有沿径向重复的凹部（5a，5b）的周向形状，以及倒角工序用于通过压在转子板（2）的外周边缘上的角部（2d）上形成倒角表面（6），模具（7）和由该方法制成的制动盘。因此，能够提高散热能力，减轻重量和转动惯量，提高搬运安全性，抑制生产成本的增加。此外，通过形成倒角表面（6），可以减少由制动盘（1）按压的制动衬块的磨损量，并且可以保持或改善制动性能的耐久性。

10. 发明授权

US07163879B2 Hard mask etch for gate polyetch 有权
标题翻译：门掩模蚀刻硬掩模
公开(公告)号：US07163879B2
公开(公告)日：2007-01-16
申请号：US10157192
申请日：2002-05-30
申请人： Koji Tamura
发明人： Koji Tamura
IPC分类号： H01L21/3205 , H01L21/302 , H01L21/31
CPC分类号： H01L21/32139 , H01L21/28035 , H01L21/31116 , H01L21/32137 , Y10S438/952
摘要： A transistor gate structure that is free from notches is formed by using a hard mask. The hard mask has a bilayer structure of a BARC (bottom antireflective coating) over a silicon dioxide layer. A photoresist layer is formed over a portion corresponding to the gates. A first etch forms the gate structure. Following removal of the photoresist, a second etch completely removes the BARC. The silicon dioxide layer can be removed by a subsequent wet etch with HF.
摘要翻译：通过使用硬掩模形成没有缺口的晶体管栅极结构。硬掩模具有在二氧化硅层上的BARC（底部抗反射涂层）的双层结构。在对应于栅极的部分上形成光致抗蚀剂层。第一蚀刻形成栅极结构。除去光致抗蚀剂后，第二次蚀刻完全去除了BARC。二氧化硅层可以用HF随后的湿法蚀刻除去。

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