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1. 发明申请

WO2007055388A3 CALCIUM RECEPTOR ACTIVATOR 审中-公开
标题翻译：钙受体激活剂
公开(公告)号：WO2007055388A3
公开(公告)日：2007-09-27
申请号：PCT/JP2006322684
申请日：2006-11-08
申请人： AJINOMOTO KK , OHSU TAKEAKI , TAKESHITA SEN , ETO YUZURU , AMINO YUSUKE
发明人： OHSU TAKEAKI , TAKESHITA SEN , ETO YUZURU , AMINO YUSUKE
IPC分类号： A61K31/198 , A61K38/05 , A61K38/06 , C07K5/06 , C07K5/08 , G01N33/566
CPC分类号： A61K38/06 , A61K38/05
摘要： A calcium receptor activator containing one or more kinds of substances selected from Á-Glu-Cys-Gly, Á-Glu-Cys(SNO)-Gly, Á-Glu-Ala, Á-Glu-Gly, Á-Glu-Cys, Á-Glu-Met, Á-Glu-Thr, Á-Glu-Val, Á-Glu-Orn, Asp-Gly, Cys-Gly, Cys-Met, Glu-Cys, Gly-Cys, Leu-Asp, D-Cys, Á-Glu-Met(O), Á-Glu-Val-Val, Á-Glu-Val-Glu, Á-Glu-Val-Lys, Á-Glu- Á-Glu-Val, Á-Glu-Val-NH2, Á-Glu-Val-ol, Á-Glu-Ser, Á-Glu-Tau, Á-Glu-Cys(S-Me)(O), Á-Glu-Leu, Á-Glu-Ile, Á-Glu-t-Leu, Á-Glu-Cys(S-allyl)-Gly, Á-Glu-Gly-Gly, Á-Glu-Val-Phe, Á-Glu-Val-Ser, Á-Glu-Val-Pro, Á-Glu-Val-Arg, Á-Glu-Val-Asp, Á-Glu-Val-Met, Á-Glu-Val-Thr, Á-Glu-Val-His, Á-Glu-Val-Asn,Á-Glu-Val-Gln, Á-Glu-Val-Cys, Á-Glu-Val-Orn, Á-Glu-Ser-Gly, Á-Glu-Cys(S-Me), Á-Glu-Abu-Gly, Á-Glu-Cys(S-Me)-Gly, and Á-Glu-Val-Gly.
摘要翻译：含有一种或多种选自Á-Glu-Cys-Gly，Á-Glu-Cys（SNO）-Gly，Á-Glu-Ala，Á-Glu-Gly，Á-Glu-Cys， Á-Glu-Met，Á-Glu-Thr，Á-Glu-Val，Á-Glu-Orn，Asp-Gly，Cys-Gly，Cys-Met，Glu-Cys，Gly-Cys，Leu-Asp， Cys，Á-Glu-Met（O），Á-Glu-Val-Val，Á-Glu-Val-Glu，Á-Glu-Val-Lys，Á-Glu-Á-Glu-Val， -NH 2，-Gal-Val-ol，-Glu-Ser，-Glu-Tau，-Glu-Cys（S-Me）（O），-Gly-Leu，-Glu-Ile， -Glu-t-Leu，Glu-Cys（S-烯丙基）-Gly，-Gly-Gly-Gly，-Glu-Val-Phe，-Gly-Val-Ser，-Gly-Val- Pro-Ala-Glu-Val-Arg，Glu-Val-Asp，-Glu-Val-Met，-Glu-Val-Thr，-Gly-Val-His， Á-Glu-Val-Gln，Á-Glu-Val-Cys，Á-Glu-Val-Orn，-Glu-Ser-Gly，-Gly-Cys（S-Me），Á-Glu-Abu-Gly ，Á-Glu-Cys（S-Me）-Gly和Á-Glu-Val-Gly。

2. 发明公开

EP2524925A4 LANTHIONINE DERIVATIVE 有权
标题翻译： LANTHIONINDERIVATE
公开(公告)号：EP2524925A4
公开(公告)日：2015-08-26
申请号：EP10841039
申请日：2010-12-28
申请人： AJINOMOTO KK
发明人： SATO SEIICHI , FUTAKI FUMIE , YASUDA REIKO , ETO SACHISE , SUZUKI YUMIKO , TAJIMA TAKAHO , ETO YUZURU , TAHARA YUKI
IPC分类号： C07K5/02 , A23C9/156 , A23L1/226 , C07D281/06
CPC分类号： A23C9/156 , A23L27/204 , C07D281/06 , C07K5/0215

3. 发明公开

EP2520180A4 FLAVOR-ENRICHING AGENT 审中-公开
标题翻译： DUFTANREICHERUNGSMITTEL
公开(公告)号：EP2520180A4
公开(公告)日：2014-12-17
申请号：EP10841040
申请日：2010-12-28
申请人： AJINOMOTO KK
发明人： MIYAKI TAKASHI , MIYAMURA NAOHIRO , KANEKO MEGUMI , AMINO YUSUKE , YASUDA REIKO , ETO YUZURU , TAJIMA TAKAHO
IPC分类号： A23L1/228 , A23L1/22 , A23L1/24 , C07K5/02 , C07K5/06 , C07K5/08
CPC分类号： C07K5/0215 , A23L27/22 , A23L27/63 , A23L27/88

4. 发明公开

EP2345636A4 CASR AGONIST 有权
标题翻译： CASR激动剂
公开(公告)号：EP2345636A4
公开(公告)日：2012-07-25
申请号：EP09817922
申请日：2009-10-05
申请人： AJINOMOTO KK
发明人： SUGIKI MASAYUKI , OKAMATSU TORU , ASARI SAYAKA , KAWATO YAYOI , HATANAKA TOSHIHIRO , YANO TETSUO , SEKI YUKIE , MIYAMURA NAOHIRO , NAGASAKI HIROAKI , ETO YUZURU , YASUDA REIKO
IPC分类号： C07F9/38 , A23L1/228 , A61K31/198 , A61K31/662 , A61P1/12 , A61P43/00 , C07C237/04 , C07C309/51 , C07F9/40
CPC分类号： C07C237/04 , A23L27/204 , A23L27/22 , A23L33/175 , C07C309/51 , C07F9/3834 , C07F9/4018 , C07F9/4021

5. 发明公开

EP2286836A4 IMMUNOSTIMULATING AGENT 审中-公开
标题翻译：免疫刺激培养基
公开(公告)号：EP2286836A4
公开(公告)日：2011-10-12
申请号：EP09733522
申请日：2009-04-17
申请人： AJINOMOTO KK
发明人： KODERA TOMOHIRO , ETO YUZURU , MINE YOSHINORI
IPC分类号： A61K45/00 , A23L1/30 , A23L2/52 , A61K31/132 , A61K31/135 , A61K38/00 , A61K38/16 , A61P1/04 , A61P1/12 , A61P31/00 , A61P35/00 , A61P37/04 , A61P37/08
CPC分类号： A61K31/132 , A23L33/10 , A23L33/18 , A61K31/135 , A61K38/03 , A61K38/17
摘要： Disclosed is an immunostimulating agent which can stimulate immunity effectively. The immunostimulating agent comprises, as an active ingredient, a calcium receptor activator such as ³-Glu-X-Gly [wherein X represents an amino acid or a derivative thereof other than Cys], ³-Glu-Val-Y [wherein Y represents an amino acid or a derivative thereof], ³-Glu-Ala, ³-Glu-Gly, ³-Glu-Met, ³-Glu-Thr, ³-Glu-Val, ³-Glu-Orn, Asp-Gly, Cys-Gly, Cys-Met, Glu-Cys, Gly-Cys, Leu-Asp, ³-Glu-Met(O), ³-Glu-y-Glu-Val, ³-Glu-Val-NH2, ³-Glu-Val-ol, ³-Glu-Ser, ³-Glu-Tau, ³-Glu-Cys(S-Me)(O), ³-Glu-Leu, ³-Glu-Ile, ³-Glu-t-Leu, ³-Glu-Cys(S-Me), a cation having a valency of 2 or more, protamine, polylysine, spermine, spermidine, putrescine, cinacalcet, a cinacalcet analogue compound, and a salt of any one of the aforementioned components.

6. 发明公开

EP1167522A4 METHOD FOR SCREENING BIOMOLECULE ACTIVITY REGULATOR 审中-公开
标题翻译：一种筛选活性生物分子稳定器的
公开(公告)号：EP1167522A4
公开(公告)日：2002-05-15
申请号：EP00908008
申请日：2000-03-10
申请人： AJINOMOTO KK
发明人： OKAMOTO SATORU , MIWA KIYOSHI , ETO YUZURU
IPC分类号： C07K1/04 , C07K7/06 , C07K7/08 , C07K14/00 , C12N9/04 , C12N15/10 , C12P7/60 , C12Q1/02 , C40B40/02 , G01N33/50 , C12N15/09 , C07K4/00 , C12Q1/00 , C12Q1/70 , G01N33/68
CPC分类号： C40B40/02 , C07K1/047 , C07K7/06 , C07K7/08 , C07K14/00 , C12N9/0006 , C12N15/1037 , C12P7/60 , C12Q1/025 , G01N33/50
摘要： A method for screening a low molecular weight substance which binds to a specific site of a biomolecule and thus may be usable as a starting material in developing drugs. This method comprises screening a substance which undergoes an interaction with a specific area of a biomolecule having an activity to thereby regulate the activity through the following steps: (a) the step of selecting a recombinant undergoing an interaction with the above-described biomolecule from a peptide library consisting of recombinants each presenting at least one of various peptides on the surface; and (b) the step of selecting a substance inhibiting the interaction between the recombinant thus selected or the peptide presented by this recombinant and the above biomolecule.

7. 发明公开

EP0598133A4 REMEDY FOR WOUND. 失效
标题翻译： WUNDHEILMITTEL。
公开(公告)号：EP0598133A4
公开(公告)日：1996-03-06
申请号：EP93908110
申请日：1993-04-19
申请人： AJINOMOTO KK
发明人： KITAHARA YOSHIRO , OHSUMI TSUYOSHI , ETO YUZURU , TAKANO SATOSHI
IPC分类号： A61K38/45 , A61K37/52
CPC分类号： A61K38/45
摘要： A novel, excellent remedy for wound which contains transglutaminase as the active ingredient and which can readily perform cicatricial contracture inhibition, wound covering and hemostasis.
摘要翻译：一种新颖的伤口治疗方法，其中含有转谷氨酰胺酶作为活性成分，可以方便地进行瘢痕性挛缩抑制，伤口覆盖和止血。

8. 发明公开

EP2622970A4 SALTY TASTE ENHANCER 审中-公开
标题翻译：咸味放大器
公开(公告)号：EP2622970A4
公开(公告)日：2014-04-16
申请号：EP10857834
申请日：2010-09-29
申请人： AJINOMOTO KK
发明人： AMINO YUSUKE , MAEKAWA TAKAMI , ETO YUZURU , KANEKO MEGUMI , TAHARA YUKI , MIYAKI TAKASHI , SAIKAWA WAKANA , KAI YUKO , ISHIWATARI YUTAKA
IPC分类号： A23L27/00 , A23L27/10 , A23L27/40 , C07C233/29 , C07C233/51 , C07C233/87 , C07C309/46 , C07D209/14 , C07D209/18 , C07D209/20 , C07D317/48 , C07D487/04
CPC分类号： C07D209/14 , A23L27/204 , A23L27/2054 , A23L27/88 , C07C233/51 , C07C235/38 , C07C235/60 , C07C237/20 , C07C309/51 , C07D209/16 , C07D209/18 , C07D209/20 , C07D317/48 , C07D317/60 , C07D487/04

9. 发明公开

EP2156846A4 PROPHYLACTIC OR THERAPEUTIC AGENT FOR DIARRHEA 失效
标题翻译：预防或治疗剂止泻
公开(公告)号：EP2156846A4
公开(公告)日：2012-03-07
申请号：EP08752258
申请日：2008-05-01
申请人： AJINOMOTO KK
发明人： YONEDA JUNYA , YANO TETSUO , SEKI YUKIE , ETO YUZURU , AMINO YUSUKE
IPC分类号： A61K45/00 , A61K31/137 , A61K38/00 , A61P1/12 , C07K5/027
CPC分类号： A61K31/137 , A61K38/00 , C07K5/0215 , C07K5/06026 , C07K5/06043 , C07K5/0606 , C07K5/06104 , C07K5/06113

10. 发明公开

EP1908492A4 METABOTROPIC GLUTAMATE RECEPTOR ACTIVATOR 审中-公开
标题翻译：代谢型谷氨酸受体激活剂
公开(公告)号：EP1908492A4
公开(公告)日：2008-12-10
申请号：EP06767132
申请日：2006-06-22
申请人： AJINOMOTO KK
发明人： TAKESHITA SEN , OHSU TAKEAKI , ETO YUZURU , TAKAHASHI MITSUO
IPC分类号： A61K31/198 , A61K31/401 , A61K31/405 , A61K31/4172 , A61K31/7076 , A61K31/708 , A61K33/06 , A61P1/00 , A61P1/02 , A61P1/14 , A61P1/16 , A61P3/04
CPC分类号： A61K31/708 , A61K31/185 , A61K31/198 , A61K31/401 , A61K31/403 , A61K31/405 , A61K31/4164 , A61K31/4172 , A61K31/7076 , A61K33/06 , G01N2333/70571 , A61K2300/00
摘要： A amino acid other than glutamic acid is used as a metabotropic glutamate receptor activator. More preferably, aspartic acid, valine or cysteine is used as a group I metabotropic glutamate receptor activator; alanine, arginine, asparagine, aspartic acid, cysteine, glutamine, glycine, histidine, isoleucine, leucine, lysine, methionine, phenylalanine, proline, serine, threonine, tryptophan, tyrosine, valine, ornithine, taurine or hydroxyproline is used as a group II metabotropic glutamate receptor activator; and cysteine is used as a group III metabotropic glutamate receptor activator.

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