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1. 发明申请

WO2005114169A1 PARALLEL PROCESSING MICROFLUID CHIP 审中-公开
标题翻译：并行处理微流控芯片
公开(公告)号：WO2005114169A1
公开(公告)日：2005-12-01
申请号：PCT/EP2004/050893
申请日：2004-05-22
申请人： AGILENT TECHNOLOGIES, INC. , GLATZ, Bernd , ANDERER, Herbert , BÄUERLE, Martin , KRAICZEK, Karsten , EICKHOFF, Jan , MÜLLER, Patrick
发明人： GLATZ, Bernd , ANDERER, Herbert , BÄUERLE, Martin , KRAICZEK, Karsten , EICKHOFF, Jan , MÜLLER, Patrick
IPC分类号： G01N30/60
CPC分类号： G01N30/466 , B01L3/5025 , B01L3/502738 , B01L2400/0622 , G01N30/20 , G01N30/6095 , G01N30/724 , G01N2030/085 , G01N2030/201 , G01N2030/202 , H01J41/04 , H01J49/04
摘要： A microfluidic chip (1; 87; 93; 149; 159; 201) with at least one inlet port, with at least one microfluidic flow path (249) coupled to the inlet port, and with at least one analytical element adapted for analyzing and/or separating components of a liquid within the flow path (249) which is arranged within or adjacent to, and/or is coupled to the microfluidic flow path (249). The microfluldic chip (1; 87; 93; 149; 159; 201) is adapted to execute at least two processes (45,47) in parallel.
摘要翻译：具有至少一个入口端口的微流体芯片（1; 87; 93; 149; 159; 201），其具有耦合到所述入口端口的至少一个微流体流动路径（249），以及适于分析和 /或分离布置在微流体流动路径（249）内或附近的流路（249）内和/或耦合到微流体流动路径（249）的流动路径（249）内的液体的组分。微型芯片（1; 87; 93; 149; 159; 201）适于并行执行至少两个过程（45,47）。

2. 发明申请

WO2005114168A1 COMBI COLUMN 审中-公开
公开(公告)号：WO2005114168A1
公开(公告)日：2005-12-01
申请号：PCT/EP2004/051079
申请日：2004-06-09
申请人： AGILENT TECHNOLOGIES, INC. , KRAICZEK, Karsten , GLATZ, Bernd
发明人： KRAICZEK, Karsten , GLATZ, Bernd
IPC分类号： G01N30/08
CPC分类号： G01N30/08 , G01N30/6095 , G01N30/7266 , G01N30/74 , G01N2030/085 , G01N2030/201 , G01N2030/382 , G01N2030/202 , G01N21/6408
摘要： A microfluidic device for sample analysis is described. The microfluidic device comprises one or more inlets (6, 7) adapted for supplying fluid sample and mobile phase to the microfluidic device, a column (2) adapted for trapping a fluid sample during a sample loading phase, and for separating components of the fluid sample during a sample analysis phase, a waste outlet (8), and a detection unit adapted for detecting the components of the fluid sample. The microfluidic device further comprises a flow path switching facility (3), said flow path switching facility being operable to couple an outlet of the column with the waste outlet during the sample loading phase, and said flow path switching facility being operable to couple the outlet of the column with the detection unit during the sample analysis phase.
摘要翻译：描述了用于样品分析的微流体装置。所述微流体装置包括一个或多个适于向所述微流体装置供应流体样品和流动相的入口（6,7），适于在样品加载阶段期间捕集流体样品的柱（2）和用于分离流体的组分在样品分析阶段期间的样品，废物出口（8）和适于检测流体样品的组分的检测单元。所述微流体装置还包括流路切换装置（3），所述流路切换装置可操作以在所述样品加载阶段期间将所述塔的出口与所述废物出口耦合，并且所述流路切换装置可操作以将所述出口在样品分析阶段使用检测单元的色谱柱。

3. 发明申请

WO2010139359A1 SAMPLE INJECTOR WITH METERING DEVICE BALANCING PRESSURE DIFFERENCES IN AN INTERMEDIATE VALVE STATE 审中-公开
标题翻译：具有计量装置的样品注射器在中间阀状态下平衡压力差
公开(公告)号：WO2010139359A1
公开(公告)日：2010-12-09
申请号：PCT/EP2009/056795
申请日：2009-06-03
申请人： AGILENT TECHNOLOGIES, INC. , KRETZ, Wolfgang , GLATZ, Bernd
发明人： KRETZ, Wolfgang , GLATZ, Bernd
IPC分类号： G01N30/32 , G01N30/20 , G01N30/36
CPC分类号： G01N30/20 , G01N30/32 , G01N30/36 , G01N2030/027 , G01N2030/207
摘要： A sample injector (200) for use in a fluid separation system (10) for separating compounds of a fluidic sample in a mobile phase, the sample injector (200) comprising a switchable valve (202), a sample loop (204) in fluid communication with the valve (202) and configured for receiving the fluidic sample, a metering device (206) in fluid communication with the sample loop (204) and configured for introducing a metered amount of the fluidic sample on the sample loop (204), and a control unit (208) configured forcontrolling switching of the valve (202) to transfer the sample loop (204) between a low pressure state and a high pressure state via an intermediate state and for controlling the metering device (206) during the intermediate state to at least partially equilibrate a pressure difference in the sample loop (204) between the low pressure state and the high pressure state.
摘要翻译：一种用于流体分离系统（10）的样品注射器（200），用于分离流动相中的流体样品的化合物，样品注射器（200）包括可切换阀（202），流体中的样品环（204）与所述阀（202）的连通并且被配置为接收流体样品;计量装置（206），其与所述样品环（204）流体连通并且被配置用于将计量量的所述流体样品引入所述样品环（204）上，以及控制单元（208），其被配置为用于控制所述阀（202）的切换以经由中间状态在低压状态和高压状态之间传送所述样品回路（204），并且用于在所述中间状态期间控制所述计量装置（206）状态以至少部分平衡在低压状态和高压状态之间的样品回路（204）中的压力差。

4. 发明授权

EP2438435B1 SAMPLE INJECTOR WITH METERING DEVICE BALANCING PRESSURE DIFFERENCES IN AN INTERMEDIATE VALVE STATE 有权
标题翻译：与测量装置中的压力波动的一个中间阀门状态补偿进样器
公开(公告)号：EP2438435B1
公开(公告)日：2014-08-20
申请号：EP09779619.7
申请日：2009-06-03
申请人： Agilent Technologies, Inc.
发明人： KRETZ, Wolfgang , GLATZ, Bernd
IPC分类号： G01N30/32 , G01N30/20 , G01N30/36
CPC分类号： G01N30/20 , G01N30/32 , G01N30/36 , G01N2030/027 , G01N2030/207
摘要： A sample injector (200) for use in a fluid separation system (10) for separating compounds of a fluidic sample in a mobile phase, the sample injector (200) comprising a switchable valve (202), a sample loop (204) in fluid communication with the valve (202) and configured for receiving the fluidic sample, a metering device (206) in fluid communication with the sample loop (204) and configured for introducing a metered amount of the fluidic sample on the sample loop (204), and a control unit (208) configured for controlling switching of the valve (202) to transfer the sample loop (204) between a low pressure state and a high pressure state via an intermediate state and for controlling the metering device (206) during the intermediate state to at least partially equilibrate a pressure difference in the sample loop (204) between the low pressure state and the high pressure state.

5. 发明公开

EP2438435A1 SAMPLE INJECTOR WITH METERING DEVICE BALANCING PRESSURE DIFFERENCES IN AN INTERMEDIATE VALVE STATE 有权
标题翻译：与测量装置中的压力波动的一个中间阀门状态补偿进样器
公开(公告)号：EP2438435A1
公开(公告)日：2012-04-11
申请号：EP09779619.7
申请日：2009-06-03
申请人： Agilent Technologies, Inc.
发明人： KRETZ, Wolfgang , GLATZ, Bernd
IPC分类号： G01N30/32 , G01N30/20 , G01N30/36
CPC分类号： G01N30/20 , G01N30/32 , G01N30/36 , G01N2030/027 , G01N2030/207
摘要： A sample injector (200) for use in a fluid separation system (10) for separating compounds of a fluidic sample in a mobile phase, the sample injector (200) comprising a switchable valve (202), a sample loop (204) in fluid communication with the valve (202) and configured for receiving the fluidic sample, a metering device (206) in fluid communication with the sample loop (204) and configured for introducing a metered amount of the fluidic sample on the sample loop (204), and a control unit (208) configured for controlling switching of the valve (202) to transfer the sample loop (204) between a low pressure state and a high pressure state via an intermediate state and for controlling the metering device (206) during the intermediate state to at least partially equilibrate a pressure difference in the sample loop (204) between the low pressure state and the high pressure state.

6. 发明授权

EP1751538B1 PARALLEL PROCESSING MICROFLUID CHIP 有权
标题翻译：微流体芯片并行处理
公开(公告)号：EP1751538B1
公开(公告)日：2009-11-18
申请号：EP04741632.6
申请日：2004-05-22
申请人： Agilent Technologies, Inc.
发明人： GLATZ, Bernd , ANDERER, Herbert , BÄUERLE, Martin , KRAICZEK, Karsten , EICKHOFF, Jan , MÜLLER, Patrick
IPC分类号： G01N30/60 , B01L3/00
CPC分类号： G01N30/466 , B01L3/5025 , B01L3/502738 , B01L2400/0622 , G01N30/20 , G01N30/6095 , G01N30/724 , G01N2030/085 , G01N2030/201 , G01N2030/202 , H01J41/04 , H01J49/04
摘要： A microfluidic chip (1; 87; 93; 149; 159; 201) with at least one inlet port, with at least one microfluidic flow path (249) coupled to the inlet port, and with at least one analytical element adapted for analyzing and/or separating components of a liquid within the flow path (249) which is arranged within or adjacent to, and/or is coupled to the microfluidic flow path (249). The microfluldic chip (1; 87; 93; 149; 159; 201) is adapted to execute at least two processes (45,47) in parallel.

7. 发明公开

EP1751538A1 PARALLEL PROCESSING MICROFLUID CHIP 有权
标题翻译：微流体芯片并行处理
公开(公告)号：EP1751538A1
公开(公告)日：2007-02-14
申请号：EP04741632.6
申请日：2004-05-22
申请人： Agilent Technologies, Inc.
发明人： GLATZ, Bernd , ANDERER, Herbert , BÄUERLE, Martin , KRAICZEK, Karsten , EICKHOFF, Jan , MÜLLER, Patrick
IPC分类号： G01N30/60 , B01L3/00
CPC分类号： G01N30/466 , B01L3/5025 , B01L3/502738 , B01L2400/0622 , G01N30/20 , G01N30/6095 , G01N30/724 , G01N2030/085 , G01N2030/201 , G01N2030/202 , H01J41/04 , H01J49/04
摘要： A microfluidic chip (1; 87; 93; 149; 159; 201) with at least one inlet port, with at least one microfluidic flow path (249) coupled to the inlet port, and with at least one analytical element adapted for analyzing and/or separating components of a liquid within the flow path (249) which is arranged within or adjacent to, and/or is coupled to the microfluidic flow path (249). The microfluldic chip (1; 87; 93; 149; 159; 201) is adapted to execute at least two processes (45,47) in parallel.

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