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1. 发明申请

WO2010030762A1 SPECTRAL TILT OPTIMIZATION FOR COCHLEAR IMPLANT PATIENTS 审中-公开
标题翻译：脊髓移植患者的光谱倾斜优化
公开(公告)号：WO2010030762A1
公开(公告)日：2010-03-18
申请号：PCT/US2009/056488
申请日：2009-09-10
申请人： ADVANCED BIONICS, LLC , SAOJI, Aniket , LITVAK, Leonid M.
发明人： SAOJI, Aniket , LITVAK, Leonid M.
IPC分类号： A61N1/36
CPC分类号： A61N1/36036 , A61B5/121 , A61N1/37247
摘要： An exemplary method of spectral tilt optimization for a cochlear implant patient includes applying electrical stimulation representative of an audio signal to the cochlear implant patient in accordance with a plurality of spectral tilt values, recording a recognition score achieved by the patient for each of the spectral tilt values, the recognition score corresponding to an ability of the patient to recognize at least one attribute of the audio signal applied in accordance with each of the spectral tilt values, and selecting one of the spectral tilt values as an optimal spectral tilt value for the patient based on the recorded recognition scores. Corresponding methods and systems are also disclosed.
摘要翻译：用于耳蜗植入患者的光谱倾斜优化的示例性方法包括根据多个光谱倾斜值将表示音频信号的电刺激应用于耳蜗植入患者，记录患者对于每个频谱倾斜度获得的识别分数值，所述识别分数对应于患者识别根据每个频谱倾斜值应用的音频信号的至少一个属性的能力，并且选择一个频谱倾斜值作为患者的最佳频谱倾斜值基于记录的识别分数。还公开了相应的方法和系统。

2. 发明申请

WO2010075370A1 COMPENSATION CURRENT OPTIMIZATION FOR COCHLEAR IMPLANT SYSTEMS 审中-公开
标题翻译： COCHLEAR植物系统的补偿电流优化
公开(公告)号：WO2010075370A1
公开(公告)日：2010-07-01
申请号：PCT/US2009/069168
申请日：2009-12-22
申请人： ADVANCED BIONICS, LLC , LITVAK, Leonid M. , SAOJI, Aniket
发明人： LITVAK, Leonid M. , SAOJI, Aniket
IPC分类号： A61N1/00
CPC分类号： A61N1/36032 , A61N1/0541 , A61N1/36036
摘要： An exemplary cochlear stimulation method includes applying a main current to a first electrode associated with a first pitch and disposed within a cochlea of a patient, concurrently applying a compensation current to a second electrode disposed within the cochlea and associated with a second pitch during the application of the main current, the compensation current being out-of-phase with the main current, and optimizing an amount of the compensation current to result in a target pitch being presented to the patient that is distanced from the first pitch in a pitch direction opposite a pitch direction of the second pitch in relation to the first pitch. Corresponding methods and systems are also disclosed.
摘要翻译：示例性的人工耳蜗刺激方法包括将主电流施加到与第一间距相关并设置在患者的耳蜗内的第一电极，同时向施加在耳蜗内的第二电极施加补偿电流并在施加期间与第二间距相关联的主电流，补偿电流与主电流异相，并且优化补偿电流的量以导致目标音调被呈现给相对于俯仰方向与第一音调远离第一音调的患者相对于第一间距的第二间距的俯仰方向。还公开了相应的方法和系统。

3. 发明申请

WO2011041156A2 METHODS AND SYSTEMS FOR REPRESENTING DIFFERENT SPECTRAL COMPONENTS OF AN AUDIO SIGNAL PRESENTED TO A COCHLEAR IMPLANT PATIENT 审中-公开
标题翻译：用于表示呈现给耳蜗植入患者的音频信号的不同光谱分量的方法和系统
公开(公告)号：WO2011041156A2
公开(公告)日：2011-04-07
申请号：PCT/US2010/049548
申请日：2010-09-20
申请人： ADVANCED BIONICS, LLC , SAOJI, Aniket , LITVAK, Leonid M.
发明人： SAOJI, Aniket , LITVAK, Leonid M.
IPC分类号： A61N1/36
CPC分类号： A61N1/36032 , A61N1/36036
摘要： An exemplary method of representing different spectral components of an audio signal presented to a cochlear implant patient includes identifying one or more spectral peaks of an audio signal presented to a cochlear implant patient, applying electrical stimulation representative of the one or more spectral peaks to at least one stimulation site within the cochlear implant patient using a partial multipolar stimulation configuration, and applying electrical stimulation representative of one or more other spectral components of the audio signal to at least one other stimulation site within the cochlear implant patient using a monopolar stimulation configuration. Corresponding methods and systems are also disclosed.
摘要翻译：表示呈现给耳蜗植入患者的音频信号的不同频谱分量的示例性方法包括：标识呈现给耳蜗植入患者的音频信号的一个或多个频谱峰值;施加代表使用部分多极刺激配置向耳蜗植入患者内的至少一个刺激位点施加一个或多个光谱峰值，并且将代表音频信号的一个或多个其他光谱分量的电刺激施加到耳蜗植入物内的至少一个其他刺激位点患者使用单极刺激配置。也公开了相应的方法和系统。

4. 发明申请

WO2013074085A1 INTERFACE SYSTEM FOR SYNCHRONIZING THE OPERATION OF A MIDDLE EAR ANALYZER AND A COCHLEAR IMPLANT SYSTEM 审中-公开
标题翻译：用于同步中间分析仪和COCHLEAR植入系统的操作的界面系统
公开(公告)号：WO2013074085A1
公开(公告)日：2013-05-23
申请号：PCT/US2011/060728
申请日：2011-11-15
申请人： ADVANCED BIONICS AG , MASAKI, Kinuko , KULKARNI, Abhijit , SAOJI, Aniket , LITVAK, Leonid M.
发明人： MASAKI, Kinuko , KULKARNI, Abhijit , SAOJI, Aniket , LITVAK, Leonid M.
IPC分类号： A61N1/36
CPC分类号： A61N1/36032 , A61B5/125 , A61N1/36036 , A61N1/37235
摘要： An exemplary system (104) for synchronizing an operation of a middle ear analyzer (102) and a cochlear implant system (106) includes 1) a mapping facility configured to maintain mapping data representative of an association between a plurality of sound levels and a plurality of current levels and between a plurality of frequencies and a plurality of electrodes, 2) a detection facility configured to receive an acoustic signal transmitted by the middle ear analyzer and detect a sound level and a frequency of the acoustic signal, and 3) a processing facility configured to identify, based on the mapping data, a current level associated with the detected sound level and one or more electrodes associated with the detected frequency and direct the cochlear implant system to apply electrical stimulation having the identified current level to one or more stimulation sites within a patient by way of the identified one or more electrodes.
摘要翻译：用于同步中耳分析仪（102）和耳蜗植入物系统（106）的操作的示例性系统（104）包括：1）配置成维持表示多个声级与多个声级之间的关联的映射数据的映射设备 2）检测设备，被配置为接收由中耳分析仪发送的声信号并检测声信号的声级和频率，以及3）处理设备，被配置为基于所述映射数据识别与所述检测到的声级相关联的当前级别和与所述检测到的频率相关联的一个或多个电极，并且引导所述人工耳蜗植入系统以将具有所识别的当前水平的电刺激施加到一个或多个刺激通过所识别的一个或多个电极在患者体内的部位。

5. 发明申请

WO2010088549A1 MODULAR COCHLEAR IMPLANT SYSTEMS INCLUDING IMPLANTABLE SOUND PROCESSORS 审中-公开
标题翻译：模块化COCHLEAR植入系统，包括可植入的声处理器
公开(公告)号：WO2010088549A1
公开(公告)日：2010-08-05
申请号：PCT/US2010/022634
申请日：2010-01-29
申请人： ADVANCED BIONICS, LLC , HALLER, Matthew I. , LITVAK, Leonid M. , KULKARNI, Abhijit
发明人： HALLER, Matthew I. , LITVAK, Leonid M. , KULKARNI, Abhijit
IPC分类号： A61N1/36
CPC分类号： A61N1/36032 , A61N1/36036 , A61N1/372 , A61N1/37229 , A61N1/3787
摘要： Exemplary cochlear implant systems (400) include an implantable head module (402) configured to be implanted within a head of a patient. The implantable head module includes a cochlear stimulator (110) configured to be coupled to an electrode lead (114), the electrode lead including one or more electrodes configured to be in communication with one or more stimulation sites within the patient. The implantable head module also includes a signal receiver (408) configured to receive a telemetry signal representative of an audio signal from a signal transmitter (420) located external to the patient, a sound processor (106) configured to process the telemetry signal and direct the cochlear stimulator to generate and apply electrical stimulation representative of the audio signal to the one or more stimulation sites via the electrode lead, and a power receiver (410) configured to receive power for operating the implantable head module from a power transmitter (422) located external to the patient.
摘要翻译：示例性的耳蜗植入物系统（400）包括构造成植入患者头部的可植入头模块（402）。可植入头模块包括被配置为耦合到电极引线（114）的耳蜗刺激器（110），所述电极引线包括被配置为与患者内的一个或多个刺激部位连通的一个或多个电极。可植入头模块还包括信号接收器（408），其被配置为从位于患者外部的信号发射器（420）接收代表音频信号的遥测信号;声音处理器（106），被配置为处理遥测信号并直接所述耳蜗刺激器通过所述电极引线产生并将代表所述音频信号的电刺激施加到所述一个或多个刺激部位;以及功率接收器（410），被配置为从功率发射器（422）接收用于操作所述可植入头模块的功率，位于患者外部。

6. 发明申请

WO2011050315A1 REMOTE AUDIO PROCESSOR MODULE FOR AUDITORY PROSTHESIS SYSTEMS 审中-公开
标题翻译：用于审计预测系统的远程音频处理器模块
公开(公告)号：WO2011050315A1
公开(公告)日：2011-04-28
申请号：PCT/US2010/053836
申请日：2010-10-22
申请人： ADVANCED BIONICS, LLC , MISHRA, Lakshmi N. , KULKARNI, Abhijit , LITVAK, Leonid M.
发明人： MISHRA, Lakshmi N. , KULKARNI, Abhijit , LITVAK, Leonid M.
IPC分类号： H04R25/00 , A61N1/36 , A61N1/372
CPC分类号： A61N1/36032 , A61N1/36036 , A61N1/37211 , H04R25/554 , H04R25/558 , H04R2225/39
摘要： An exemplary auditory prosthesis system includes an auditory prosthesis configured to be implanted within a head of a patient and to apply electrical stimulation representative of an audio signal to one or more stimulation sites within the patient in accordance with one or more stimulation parameters, a behind-the-ear sound processing unit configured to be secured to an ear of the patient and to transmit the one or more stimulation parameters to the auditory prosthesis, and a remote audio processor module separate from the behind-the-ear sound processing unit and communicatively coupled to the behind-the-ear sound processing unit via a communication link, the remote audio processor module configured to perform at least a portion of a signal processing heuristic on the audio signal in order to facilitate generation of the one or more stimulation parameters. Corresponding systems and methods are also disclosed.
摘要翻译：示例性听觉假体系统包括被配置为植入患者头部内的听觉假体，并且根据一个或多个刺激参数将代表音频信号的电刺激施加到患者体内的一个或多个刺激部位，耳声音处理单元被配置为固定到患者的耳朵并且将一个或多个刺激参数传送到听觉假体，以及远程音频处理器模块，与耳后声音处理单元分离并且通信耦合经由通信链路传送到耳后声音处理单元，所述远程音频处理器模块被配置为对音频信号执行信号处理启发式的至少一部分，以便于产生一个或多个刺激参数。还公开了相应的系统和方法。

7. 发明申请

WO2017065809A1 SYSTEMS AND METHODS FOR INTRA-SURGICAL MONITORING OF EVOKED RESPONSES THAT OCCUR DURING AN ELECTRODE LEAD INSERTION PROCEDURE 审中-公开
标题翻译：用于在电极导线插入程序期间进行诱发反应的手术中监测的系统和方法
公开(公告)号：WO2017065809A1
公开(公告)日：2017-04-20
申请号：PCT/US2015/058879
申请日：2015-11-03
申请人： ADVANCED BIONICS AG , KOKA, Kanthaiah , LITVAK, Leonid M.
发明人： KOKA, Kanthaiah , LITVAK, Leonid M.
IPC分类号： A61N1/05 , A61N1/36
CPC分类号： A61N1/0541 , A61N1/36036
摘要： An exemplary monitoring system 1) receives a user input command to begin monitoring evoked responses that occur in response to acoustic stimulation during an insertion procedure in which a lead that is communicatively coupled to a cochlear implant is inserted into a cochlea of a patient, the lead having an array of intracochlear electrodes and an extracochlear electrode, the extracochlear electrode physically and communicatively coupled to a probe that is also communicatively coupled to the monitoring system, 2) directs, in response to the user input command, the cochlear implant to short an intracochlear electrode with the extracochlear electrode, 3) presents the acoustic stimulation to the patient, and 4) records the evoked responses that occur in response to the acoustic stimulation by using the intracochlear electrode to detect signals representative of the evoked responses and receiving the detected signals by way of the extracochlear electrode and the probe.
摘要翻译：示例性监视系统1）接收用户输入命令以开始监视在插入过程期间响应于声刺激而发生的诱发响应，其中通信地耦合到耳蜗植入物的引线被插入患者的耳蜗，所述引线具有耳蜗内电极阵列和耳蜗外电极，所述耳蜗外电极在物理上并且通信地耦合到也通信地耦合到所述监测系统的探头，2）响应于所述用户输入命令，耳蜗植入物用耳蜗外电极使耳蜗内电极短路，3）向患者呈现声刺激，以及4）通过使用耳蜗内电极来检测响应于声刺激而发生的诱发响应，以检测代表诱发反应，并通过耳蜗外电极和探头接收检测信号。

8. 发明申请

WO2012161717A1 SYSTEMS AND METHODS FOR IMPROVING REPRESENTATION BY AN AUDITORY PROSTHESIS SYSTEM OF AUDIO SIGNALS HAVING INTERMEDIATE SOUND LEVELS 审中-公开
标题翻译：通过具有中级声级的音频信号的审计预测系统来改进表示的系统和方法
公开(公告)号：WO2012161717A1
公开(公告)日：2012-11-29
申请号：PCT/US2011/038169
申请日：2011-05-26
申请人： ADVANCED BIONICS AG , LITVAK, Leonid M. , OKUYAMA, Nobutaka , KULKARNI, Abhijit
发明人： LITVAK, Leonid M. , OKUYAMA, Nobutaka , KULKARNI, Abhijit
IPC分类号： A61N1/05
CPC分类号： H04R25/50 , A61N1/0541 , A61N1/36036 , H03G3/20
摘要： An exemplary system includes a detection facility configured to detect an input sound level of an audio signal presented to an auditory prosthesis patient; and an adaptive gain control (AGC) facility configured to 1) determine whether the detected input sound level is in a quiet region, an intermediate region, or a loud region, and 2) apply a gain to the audio signal in accordance with an AGC gain function that specifies the gain to be substantially equal to or less than a first gain threshold if the detected input sound level is in the quiet region, substantially equal to or less than a second gain threshold if the detected input sound level is in the loud region, and greater than the first and second gain thresholds if the detected input sound level is in the intermediate region. Corresponding systems and methods are also disclosed.
摘要翻译：示例性系统包括被配置为检测呈现给听觉假体患者的音频信号的输入声级的检测设备; 以及自适应增益控制（AGC）设备，其被配置为：1）确定检测到的输入声级是否在安静区域，中间区域或大声区域中，以及2）根据AGC来对音频信号应用增益增益函数，如果检测到的输入声级在安静区域中，如果检测到的输入声音水平大致等于或小于第二增益阈值，则将增益指定为基本上等于或小于第一增益阈值并且如果检测到的输入声音电平处于中间区域，则大于第一和第二增益阈值。还公开了相应的系统和方法。

9. 发明申请

WO2012150928A1 SYSTEMS FOR OPTIMIZING A COMPLIANCE VOLTAGE OF AN AUDITORY PROSTHESIS 审中-公开
标题翻译：用于优化审计报告合规电压的系统
公开(公告)号：WO2012150928A1
公开(公告)日：2012-11-08
申请号：PCT/US2011/034860
申请日：2011-05-02
申请人： ADVANCED BIONICS AG , LITVAK, Leonid M.
发明人： LITVAK, Leonid M.
IPC分类号： A61N1/36 , H04R25/00
CPC分类号： A61N1/36 , A61N1/025 , A61N1/0541 , A61N1/36036
摘要： Exemplary systems and methods for optimizing a compliance voltage of an auditory prosthesis are disclosed. Each stimulation channel formed by electrodes that are coupled to an auditory prosthesis may have an adjustable current steering range associated therewith. Each adjustable current steering range is centered about the midpoint of its respective stimulation channel and defines a range of current steering that may be used within its respective stimulation channel. A compliance voltage of an auditory prosthesis may be optimized by setting a current steering range for one or more stimulation channels to a value that results in an optimum balance between power conservation and performance of the auditory prosthesis.
摘要翻译：公开了用于优化听觉假体的顺应性电压的示例性系统和方法。由耦合到听觉假体的电极形成的每个刺激通道可以具有与之相关联的可调节的电流操舵范围。每个可调整的电流转向范围围绕其各自的刺激通道的中点居中，并且限定可在其各自的刺激通道内使用的电流转向的范围。可以通过将一个或多个刺激通道的当前转向范围设置为导致功率保持和听觉假体的性能之间的最佳平衡的值来优化听觉假体的顺应性电压。

10. 发明申请

WO2019045747A1 ELECTRODE LOCATING SYSTEMS AND METHODS FOR USE WITHIN A COCHLEAR IMPLANT PATIENT 审中-公开
公开(公告)号：WO2019045747A1
公开(公告)日：2019-03-07
申请号：PCT/US2017/049792
申请日：2017-08-31
申请人： ADVANCED BIONICS AG , KOKA, Kanthaiah , LITVAK, Leonid M.
发明人： KOKA, Kanthaiah , LITVAK, Leonid M.
IPC分类号： A61N1/36 , A61N1/05 , A61B5/06
摘要： An exemplary electrode locating system performs an excitation spread measurement by directing a first electrode to generate an electrical pulse and, in response to the generation of the electrical pulse, detecting a voltage between a second electrode and a reference that are both distinct from the first electrode. The first and second electrodes are included in a plurality of electrodes disposed on an electrode lead included within a cochlear implant system and that comprises a proximal portion configured to be coupled with a cochlear implant and a distal portion configured to be inserted into a cochlea of a patient by way of an insertion procedure. Based on the excitation spread measurement, the electrode locating system determines whether at least one of the first electrode and the second electrode is located within the cochlea. Corresponding methods are also described.

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